Cell state · L2
T.CD4_naive.gut_prone
801 cells in the full atlas (not the displayed sample).
These are the cell-population annotations shown in the SCREATE Cell Browser.
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Marker genes
CCR9, SOX4, TOX2
Annotation genes
CCR9, SOX4, TOX2
Annotation rationales
CCR9 imprints small-intestine homing to CCL25⁺ epithelium; SOX4 and TOX2 align with recent-thymic-emigrant-like maturation and chromatin poising for lineage choice. The trio (CCR9, SOX4, TOX2) suggests a gut-tropic naïve source pool.
Functional implications
Seed GALT and epithelium-proximal niches, providing precursors that rapidly polarize to Th17/Th22/Th2 according to mucosal cues.
Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.