Cell state · L2
T.CD4_naive.Treg_like
735 cells in the full atlas (not the displayed sample).
These are the cell-population annotations shown in the SCREATE Cell Browser.
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Marker genes
CEACAM4, EGR1, FCRL3, FOXP3, FXYD2, IL2RB, LAIR2, RTKN2, TIGIT
Annotation genes
EGR1, FOXP3, IL2RB, LAIR2, TIGIT
Annotation rationales
FOXP3 (low) with TIGIT/LAIR2/IL2RB marks a naïve-like regulatory tone (not full eTreg). EGR1 indicates recent tonic signaling exposure.
Functional implications
Provide mild systemic suppression (IL-2 consumption, ITIM-mediated brakes) while retaining naïve trafficking and expansion potential.
Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.