Cell state · L2
T.CD4_Th17.migratory
1,241 cells in the full atlas (not the displayed sample).
These are the cell-population annotations shown in the SCREATE Cell Browser.
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Marker genes
AQP3, CCR6, CCR7, LIMS1, PIM2, RNASET2, USP10
Annotation genes
AQP3, CCR6, CCR7, USP10
Annotation rationales
CCR6 ensures mucosal homing; CCR7 confers LN recirculation; AQP3/USP10 sustain oxidative stress control—together a shuttling Th17 pool.
Functional implications
Patrol between LNs and mucosa to provide rapid IL-17/IL-22 upon early inflammation, scaling up neutrophil recruitment when needed.
Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.