Cell state · L2
T.CD4_Th17.baseline
2,545 cells in the full atlas (not the displayed sample).
These are the cell-population annotations shown in the SCREATE Cell Browser.
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Marker genes
AQP3, BATF, CCR6, FUT7, KLRB1, RORC, STAT3, USP10
Annotation genes
BATF, CCR6, RORC, STAT3
Annotation rationales
RORC/STAT3/BATF define the Th17 lineage and IL-17A/F competence; CCR6 (with KLRB1 in markers) ensures migration to CCL20⁺ mucosa; AQP3/USP10 support redox and survival in barrier tissues.
Functional implications
Provide homeostatic IL-17/IL-22 to maintain epithelial integrity, induce antimicrobial peptides, and recruit neutrophils at barriers.
Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.