Cell state · L2
T.CD4_Tfh.precursor_migratory
1,736 cells in the full atlas (not the displayed sample).
These are the cell-population annotations shown in the SCREATE Cell Browser.
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Marker genes
CCR7, CHMP1B, CMTM8, CXCR4, DNAJB1, FAM177A1, FOS, FOSB, GPR183, IFRD1, IL7R, KLF6, MAL, MORF4L2, PER1, SF1, SNHG8, SOCS3, SPRY1, SRSF7, WDR74, YPEL5, ZFAS1
Annotation genes
CCR7, CXCR4, GPR183, IL7R
Annotation rationales
CCR7/IL7R mark circulating memory precursors; GPR183 targets the T–B border; CXCR4 biases toward GC dark zone interactions; IEGs (FOS/FOSB in markers) indicate recent priming.
Functional implications
Home to T–B borders and differentiate into GC Tfh on antigen encounter, seeding GC reactions with appropriate spatial programming.
Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.