Cell subtype · L1S
MAC.resident_iron
3,391 cells in the full atlas (not the displayed sample).
These are the cell-population annotations shown in the SCREATE Cell Browser.
Read trait, study and gene evidence reports for this population →
Explore this population in Cell Browser →
Marker genes
CD163, HMOX1, FTH1, FTL, SLC40A1
Annotation genes
CD163, HMOX1, SLC40A1
Annotation rationales
Resident iron-handling macrophages are tissue phagocytes specialized for haemoglobin uptake, haem catabolism and iron storage or export.
Functional implications
They recycle iron from aged or damaged erythrocytes, protect tissues from haem toxicity and help maintain systemic iron availability.
More specific populations
Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.