SCREATE

Cell subtype · L1S

MAC.resident_cardiac

8,086 cells in the full atlas (not the displayed sample).

These are the cell-population annotations shown in the SCREATE Cell Browser.

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Marker genes

C1QC, LYVE1, FOLR2, MRC1, CD163

Annotation genes

FOLR2, LYVE1, C1QC

Annotation rationales

Resident cardiac macrophages are long-lived heart phagocytes adapted to myocardial, vascular and conduction-system niches.

Functional implications

They clear debris, support vessels and cardiomyocytes, regulate electrical and structural homeostasis and coordinate inflammation and repair after cardiac injury.

More specific populations

Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.