SCREATE

Cell subtype · L1S

MAC.proliferating

1,228 cells in the full atlas (not the displayed sample).

These are the cell-population annotations shown in the SCREATE Cell Browser.

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Marker genes

MKI67, TOP2A, TYMS, CD68, CSF1R

Annotation genes

MKI67, TOP2A, CD68

Annotation rationales

Proliferating macrophages are macrophage-lineage cells actively traversing the cell cycle while retaining phagocyte identity.

Functional implications

Local expansion replenishes macrophage compartments during development, homeostasis or sustained tissue demand without relying solely on monocyte recruitment.

More specific populations

Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.