SCREATE

Cell state · L2

MAC.LAM.antimicrobial

2,027 cells in the full atlas (not the displayed sample).

These are the cell-population annotations shown in the SCREATE Cell Browser.

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Marker genes

IFI6, IL2RG, LGALS2, LYZ, SDS, SPARC

Annotation genes

IFI6, IL2RG, LYZ

Annotation rationales

IFI6 (ISG) and LYZ (antibacterial enzyme) denote antimicrobial vigilance; IL2RG ensures responsiveness to γ-chain cytokines (IL-2/4/7/9/15/21). Annotation genes support anti-pathogen activity in adipose depots.

Functional implications

Detect and curb microbial/viral incursions within fat, shaping local immunity via γ-chain cytokines (IL2RG) while degrading bacteria (LYZ).

Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.