Cell state · L2
IPSC.proliferative
12,587 cells in the full atlas (not the displayed sample).
These are the cell-population annotations shown in the SCREATE Cell Browser.
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Marker genes
AURKB, CDC25C, CDCA3, CDCA5, CENPK, CENPW, CKS1B, DIAPH3, DTL, E2F7, FEN1, MELK, NDC80, ORC6, PCLAF, RANBP1, RRM2, SPC25, UBE2T, ZWINT
Annotation genes
AURKB, CDCA3, E2F7, MELK, RRM2
Annotation rationales
Mitotic regulators AURKB, CDCA3, DNA synthesis RRM2, and G1/S TF E2F7 (with MELK) identify a high-fraction S/G2/M iPSC subpopulation that fuels expansion. These Annotation genes collectively capture the cycling engine needed for scalable culture.
Functional implications
Provides high self-renewal output for banking/expansion; ideal inoculum for synchronous induction, giving tight developmental timing and improved batch-to-batch reproducibility in differentiation pipelines.
Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.