Cell type · L1
induced_pluripotent_stem_cell
65,844 cells in the full atlas (not the displayed sample).
These are the cell-population annotations shown in the SCREATE Cell Browser.
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Marker genes
POU5F1, SOX2, NANOG, LIN28A, DPPA4
Annotation genes
POU5F1, SOX2, NANOG
Annotation rationales
Induced pluripotent stem cells are reprogrammed cells maintained by the core OCT4–SOX2–NANOG pluripotency network and capable of generating derivatives of all three germ layers.
Functional implications
They provide a self-renewing platform for developmental modelling, disease studies and directed production of differentiated cell types.
More specific populations
Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.