Cell state · L2

IPSC.neural_primed

4,947 cells in the full atlas (not the displayed sample).

These are the cell-population annotations shown in the SCREATE Cell Browser.

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Marker genes

ANGPT1, APLNR, BTBD17, CRABP1, EGR2, EPHA7, FABP7, FAM107A, GLUD2, KLHDC8B, LRRC7, MAGEL2, NRGN, PTX3, RFX4, TSPAN7

Annotation genes

CRABP1, EGR2, EPHA7, FABP7, NRGN

Annotation rationales

FABP7 (radial glia/NSC), CRABP1 (retinoid shuttling), EPHA7 (axon guidance), EGR2 (neurulation/segmental identity), and synaptic NRGN reflect a retinoid-responsive neural progenitor state. Inclusion of these Annotation genes highlights competence for neuroectoderm without losing proliferative potential.

Functional implications

Efficiently differentiates into cortical/forebrain-like NPCs and early neurons under dual-SMAD inhibition ± RA; provides a uniform starting population for neuronal subtype patterning and organoid formation.

Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.