Cell state · L2
FIB.suburothelial.urothelial_interface
607 cells in the full atlas (not the displayed sample).
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Marker genes
CXCL14, ENPP2, F3, KRT18, NELL2, PLPPR4, RASD1, RBFOX1, SLC14A1, SOSTDC1, STMN1, THBS2
Annotation genes
CXCL14, ENPP2, SLC14A1, THBS2
Annotation rationales
Edge fibroblasts produce CXCL14 to recruit DCs; ENPP2 (autotaxin) generates LPA that stimulates epithelial closure; SLC14A1 (UT-B) reflects adjacency to urothelial water/urea flux; THBS2 coordinates epithelial–matrix adhesion.
Functional implications
Mediates stromal–urothelial dialogue for barrier restitution and sensation; provides LPA/chemokine cues to reseal the surface and calibrate immune presence at the lumen interface.
Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.