Cell state · L2
FIB.skin_tenogenic.baseline
280 cells in the full atlas (not the displayed sample).
These are the cell-population annotations shown in the SCREATE Cell Browser.
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Marker genes
CNN2, COL11A1, COL1A1, EDNRA, MEF2C, MYL4, POSTN, SPARC, TNMD
Annotation genes
CNN2, COL11A1, COL1A1, EDNRA, POSTN, SPARC, TNMD
Annotation rationales
Tenomodulin (TNMD) and fibrillar collagens define tendon/enthesis-like fibroblasts. POSTN/SPARC orchestrate fibril cross-linking; CNN2/MYL4/MEF2C enable mechano-responsive cytoskeleton; EDNRA couples endothelin to contractile/ECM programs.
Functional implications
Builds high-tension collagen arrays in reticular dermis/appendage insertions; senses load and adapts fiber thickness/spacing; stabilizes hair unit anchorage and provides a tensioned scaffold for efficient wound contraction without scarring.
Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.