Cell state · L2
FIB.skin_papillary.baseline
149 cells in the full atlas (not the displayed sample).
These are the cell-population annotations shown in the SCREATE Cell Browser.
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Marker genes
AQP1, BGN, COMP, CRABP2, CXCL14, DKK3, LRRC15
Annotation genes
AQP1, BGN, COMP, CRABP2, CXCL14, DKK3, LRRC15
Annotation rationales
Papillary fibroblasts neighbor epidermis. CRABP2 channels retinoids to direct keratinocyte differentiation; DKK3 modulates Wnt cues for hair/appendage patterning; CXCL14 recruits dendritic cells. BGN/COMP build fine, compliant ECM; AQP1 supports interstitial fluid flux; LRRC15 marks activated matrix interactors.
Functional implications
Sustains epidermal fitness and appendage patterning; presents chemokine signals for immune surveillance; maintains a hydrated, compliant papillary bed that enables rapid re-epithelialization after micro-injury.
Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.