Cell state · L2
FIB.reticular.immune_interface
333 cells in the full atlas (not the displayed sample).
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Marker genes
BIRC3, BST2, CD59, CD74, CHN1, CLU, HLA-DRB1, IFI27, IFI30, IL32, TNC, UBD, VCAM1
Annotation genes
CD74, HLA-DRB1, IFI30, IL32, VCAM1
Annotation rationales
Antigen-presenting capacity (CD74/HLA-DR) with interferon-stimulated genes (IFI27/IFI30/BST2) and VCAM1 implies direct lymphocyte docking and education in inflamed dermis; TNC stiffens matrix to organize immune foci.
Functional implications
Serves as an immune platform that captures antigen, presents to T cells, and anchors leukocytes, orchestrating immune architecture during dermatitis while preserving matrix order.
Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.