Cell state · L2
FIB.perivascular_interface.vascular_BM_remodelling
289 cells in the full atlas (not the displayed sample).
These are the cell-population annotations shown in the SCREATE Cell Browser.
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Marker genes
ABCA10, ABCA8, APOD, DDIT4, GADD45G, KATNBL1, LAMA2, NME3, PIK3R3, SLC2A3, TRIM4
Annotation genes
ABCA10, ABCA8, APOD, DDIT4, LAMA2
Annotation rationales
Builds and services the vascular basement membrane (LAMA2) while managing sterol traffic (ABCA8/10, APOD). DDIT4 restrains mTOR under hypoxia; SLC2A3 ensures glucose import for high-demand zones.
Functional implications
Reinforces BM to resist shear and inflammation; adjusts metabolism to hypoxic perivascular niches; preserves barrier integrity and allows adaptive thickening/thinning during repair.
Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.