Cell state · L2
FIB.perivascular_interface.lipid_shuttle
332 cells in the full atlas (not the displayed sample).
These are the cell-population annotations shown in the SCREATE Cell Browser.
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Marker genes
APOE, IGFBP4, PRDX1
Annotation genes
APOE, IGFBP4, PRDX1
Annotation rationales
Perivascular fibroblasts manage lipid and growth-factor flux around microvessels. APOE handles cholesterol efflux; IGFBP4 maintains endothelial quiescence; PRDX1 reduces H₂O₂, protecting the glycocalyx.
Functional implications
Maintains clean vessel walls and controlled IGF tone to prevent leak/neoangiogenesis; shields endothelium from oxidative stress in reflux-exposed esophageal mucosa.
Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.