Cell state · L2
FIB.lung_alveolar.stress_interacting
112 cells in the full atlas (not the displayed sample).
These are the cell-population annotations shown in the SCREATE Cell Browser.
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Marker genes
ABCA6, COL3A1, DPYD, EFCAB7, EPM2AIP1, ETNK1, GAB1, JAK2, LIMA1, NEAT1, NEBL, NFKBIZ, PGAP1, PRKAA2, PTBP2, RBM39, RIC1, SLC38A2, WSB1
Annotation genes
ABCA6, COL3A1, JAK2, NFKBIZ, PRKAA2
Annotation rationales
JAK2/NFKBIZ indicate sensitivity to cytokines; AMPK (PRKAA2) reprograms energetics during hypoxia/inflammation. COL3A1 adds flexible collagen to injured septa; NEAT1/PTBP2/RBM39 point to RNA-level plasticity in stress.
Functional implications
Senses alveolitis and adjusts both metabolism and ECM deposition to preserve barrier function; communicates with epithelium/immune cells and can pivot toward early fibrotic reinforcement if injury persists.
Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.