Cell state · L2
EPI.lung_multiciliated.baseline
319 cells in the full atlas (not the displayed sample).
These are the cell-population annotations shown in the SCREATE Cell Browser.
Read trait, study and gene evidence reports for this population →
Explore this population in Cell Browser →
Marker genes
CCDC78, CFAP126, CFAP157, CFAP45, CFAP53, CFAP73, DNAH12, DNAI2, DRC1, DYNLRB2, ENKUR, RSPH1, RSPH9, SPAG6, TEKT1, TEKT2, TPPP3, TTC29, TUBA4B
Annotation genes
DNAH12, DNAI2, DRC1, RSPH1, TEKT1
Annotation rationales
Dominant axoneme-building program: dynein arms (DNAH12, DNAI2, DYNLRB2), radial spokes (RSPH1/9), tektins (TEKT1/2), nexin–dynein–regulatory complex (DRC1), microtubules (TUBA4B), and many CFAP scaffolds. Expanded: these components specify 9+2 axoneme integrity and beat coordination; ENKUR/TPPP3 aid microtubule dynamics essential for waveform stability.
Functional implications
Active ciliogenesis/repair: elongate and stabilize microtubule doublets, assemble dynein arms/spokes, tune beat mechanics—typical of ciliated cells regenerating after injury or differentiating from club/basal precursors. Restores mucociliary transport capacity in the airway.
Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.