Cell subtype · L1S
EPI.ileal_goblet
1,565 cells in the full atlas (not the displayed sample).
These are the cell-population annotations shown in the SCREATE Cell Browser.
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Marker genes
MUC2, CLCA1, SPINK4, FCGBP, AGR2, SPDEF
Annotation genes
MUC2, CLCA1, SPDEF, AGR2
Annotation rationales
Ileal goblet cells are secretory epithelial cells devoted to producing and packaging gel-forming mucin. SPDEF and AGR2 support goblet differentiation and the high secretory load.
Functional implications
They build the intestinal mucus layer, trap microbes and deliver protective factors that separate luminal contents from the epithelial surface.
More specific populations
Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.