Cell state · L2
EPI.ileal_goblet.baseline
627 cells in the full atlas (not the displayed sample).
These are the cell-population annotations shown in the SCREATE Cell Browser.
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Marker genes
ATOH1, CCL24, CLCA1, GALNT8, REG4, REP15, RETNLB, SPINK4, TPSG1, ZG16
Annotation genes
CLCA1, REG4, SPINK4, ZG16
Annotation rationales
Canonical goblet program with CLCA1 (mucus hydration), ZG16 (lectin-mediated bacterial agglutination), SPINK4 (protease inhibition), and REG4 (trophic/repair). ATOH1 locks secretory fate.
Functional implications
Produces a continuous mucus barrier, hydrates and structures the gel, agglutinates bacteria, and supplies protease inhibitors—maintaining host–microbe homeostasis along the ileal axis.
Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.