Association counts use unique genes with 01-High Priority evidence and unique cells in the authored Specific tier (not the IC-score significance threshold). Reverse counts list meta traits and individual traits separately; these are overlapping levels of evidence, not independent totals. Counts cover the full available catalogue, not the displayed rows or sampled UMAP. Unavailable profiles are excluded from reverse counts; a dash means unavailable or an ambiguous identity, not zero. The browser initially shows 50 rows; choose Rows to change this. Complete rows remain in the HTML, and ordinary page links expose any continuation pages for AI readers and crawlers.

GCST90475673 · All tissues

Type 2 diabetes with ophthalmic manifestations (PheCode 250.23): evidence report

How association tiers are defined — cell–trait and gene–trait

SCREATE tier definitions supplied by the atlas curator. This methods note explains the prepared classifications; it does not recompute or change any report scores or tiers.

Cell–trait tiers

Cell–trait links: Identify cell types whose regulatory activity is associated with a trait’s genetic signal.
Required for Specific or Relevant: The ICE-CREAM score derived from the mean metacell Z score must be ≥ 5.39, with BOTH nominal and adjusted ICE-CREAM P values ≤ 0.05.
Specific (Tier 1): Also meets all cell-set enrichment analysis (CSEA) criteria in at least one tested comparison: nominal P ≤ 0.05 AND adjusted P ≤ 0.05 AND normalized enrichment score (NES) ≥ 1, all in that comparison. This indicates that trait-associated activity is concentrated in this cell type relative to the tested background.
Relevant (Tier 2): Meets the ICE-CREAM requirements but not the additional CSEA criteria. The cell type may share trait-associated activity with other cell types.
Interpretation and report values: CSEA is cell-set enrichment analysis, analogous to gene-set enrichment analysis but using sets of cells along a ranked list of ICE-CREAM scores. The eligibility score derived from the mean metacell Z score is not the displayed mean IC score. Do not infer a tier from the displayed mean, its descriptive Significance column, or a single CSEA summary value. Reports preserve prepared tiers; Other means an available association outside Specific/Relevant, and unavailable is not zero or proof of biological irrelevance.
Meta traits and individual traits: Use the prepared tier for the exact meta trait or individual trait. A meta trait’s Best child CSEA FDR is the lowest available child FDR, not a combined or meta-trait significance test. Its displayed mean child NES is descriptive, not a new CSEA test. These summaries must not be used to reconstruct or override the meta-trait tier.

Gene–trait priorities (variant–tCRE–gene evidence)

Variant–tCRE–gene links: Candidate variants connect to genes through overlapping promoters or distal transcribed cis-regulatory elements (tCREs) linked to gene promoters by the Activity-by-Contact (ABC) model.
Required genetic support: The variant belongs to a purity-passing SuSiE credible set OR qualifies for Borzoi rescue. Borzoi rescue requires BOTH a variant-causality score ≥ 0.3 AND linkage disequilibrium with the lead variant of r² ≥ 0.2.
Required cellular support: The overlapping promoter has positive tCRE activity OR the distal element has a passing cell-specific ABC link to the gene, in a Specific or Relevant cell subtype (L1S) or fine-grained state (L2). BOTH genetic and cellular support are required for High or Medium priority.
High priority: Among records meeting both minimum requirements, High requires a genetic score ≥ 0.5 AND a Layer 1 correlation > 0.3 between tCRE activity and the trait’s cellular profile across cell subtypes.
Medium priority: Meets both minimum requirements but not one or both additional High thresholds. The genetic score is the higher of the SuSiE posterior inclusion probability (PIP) and the Borzoi variant-causality score.
Same-record evidence and aggregation: Each priority requires genetic and cellular evidence supporting the SAME variant–tCRE–gene record. Do not combine thresholds or evidence from different records to create a qualifying link. A gene receives the highest priority observed among its supporting records. A tCRE summary uses supporting records for that exact tCRE, not every trait of its linked genes. Separately displayed aggregate scores do not relax the same-record rule.
Limits of interpretation: A priority is candidate-association evidence, not proof of a causal variant, causal gene, causal cell type or treatment efficacy. Missing evidence is unavailable, not zero. MAGMA −log10(P), displayed credibility scores, cellular-context scores and G/C tier codes must not be substituted for these eligibility tests; use the provided records and their documented fields.

ICE-CREAM (IC) is −log10(P) from a permutation test. An IC score of 3 corresponds to an unadjusted P value of 0.001; 5.5 is the multiple-testing-corrected significance threshold across all metacells. The Significance categories are Significant for IC > 5.5, Nominal for 3 ≤ IC ≤ 5.5, and Nonsignificant for IC < 3. These reports display mean IC scores across full-atlas populations, not the UMAP sample. The categories apply to the displayed scores: a cell-group mean or an average across individual traits is descriptive and is not itself a newly tested P value or a new multiple-testing correction. All scores are retained. Enrichment is not proof of causality or treatment efficacy.

Open this trait in Cell Browser →

Meta trait: Diabetes, type 2 with complication

Interpret only the requested hierarchy level (L1, L1S or L2) and the exact cell identities listed for that level on the permanent reference page for the requested scope. Cell names link to their shared scope memberships. Membership is trait-independent and based on positive full-population overlap, not sampled points. A population can overlap several scopes. Cell-identity scopes include only the population itself and its ancestors, never its descendants: an L1 type does not list child L1S subtypes or L2 states. Tissue, system, lineage and theme scopes retain their full-population overlap memberships. These IC scores and cell counts remain full-atlas values: selecting a scope restricts which populations are interpreted; it does not recalculate tissue-specific averages. Do not interpret other levels or out-of-scope populations.

Scope reference: eligible cells by level · Cell-to-scope memberships

Complete annotation marker lists · Complete markers and scope-aware enriched-gene evidence for all cell types, subtypes and states. Co-interpret eligible cell rankings with the associated-gene table below using both annotation-marker overlap and scope-pooled enriched-gene overlap, kept separate. Read each relevant cell's complete marker and enrichment lists through the linked reference. These support biological interpretation, not marker recaps, causal proof or a replacement for interpreting the ranking.

Type rankings — L1 (34)

Types ranked by mean IC score
#	Cell population	Mean IC score	Significance	CSEA FDR	CSEA NES	Tier	Meta traits (Specific)	Individual traits (Specific)
1	induced_pluripotent_stem_cell	89.55	Significant	3.30e-49	1.23	Relevant	0	0
2	adipocyte	31.30	Significant	1.00	1.14	Relevant	33	111
3	hepatocyte	10.57	Significant	1.00	1.02	Specific	1,515	3,822
4	neuron	8.70	Significant	1.00	0.98	Specific	330	1,328
5	monocyte	4.74	Nominal	1.00	1.00	Other	2,176	3,871
6	epithelial_cell	4.49	Nominal	1.00	0.96	Other	24	47
7	granulosa_cell	4.25	Nominal	1.00	0.88	Other	293	670
8	haematopoietic_progenitor_cell	3.01	Nominal	1.00	0.82	Other	262	502
9	platelet	2.94	Nonsignificant	—	0.84	Other	85	104
10	melanocyte	2.62	Nonsignificant	1.00	0.88	Other	97	309
11	astrocyte	2.42	Nonsignificant	1.00	0.88	Other	256	1,203
12	oligodendrocyte_precursor_cell	1.26	Nonsignificant	1.00	0.84	Other	461	1,454
13	endothelial_cell	0.94	Nonsignificant	1.00	0.77	Other	373	974
14	smooth_muscle_cell	0.83	Nonsignificant	1.00	0.74	Other	27	139
15	dendritic_cell	0.69	Nonsignificant	1.00	0.80	Other	496	724
16	innate_lymphoid_cell_2	0.40	Nonsignificant	1.00	0.98	Other	3	8
17	granulocyte	0.26	Nonsignificant	1.00	0.69	Other	5	6
18	macrophage	0.26	Nonsignificant	1.00	0.67	Other	813	1,732
19	thymocyte	0.26	Nonsignificant	1.00	0.78	Other	168	512
20	B_cell	0.25	Nonsignificant	1.00	0.68	Other	356	694
21	plasma_cell	0.23	Nonsignificant	1.00	0.63	Other	17	24
22	fibroblast	0.20	Nonsignificant	1.00	0.65	Other	184	826
23	pericyte	0.09	Nonsignificant	1.00	0.61	Other	128	517
24	mesothelial_cell	0.09	Nonsignificant	1.00	0.58	Other	6	36
25	microglia	0.08	Nonsignificant	1.00	0.55	Other	61	129
26	adipose_stem_and_progenitor_cell	0.07	Nonsignificant	1.00	0.57	Other	327	954
27	cardiomyocyte	0.02	Nonsignificant	1.00	0.75	Other	533	2,045
28	oligodendrocyte	0.02	Nonsignificant	1.00	0.49	Other	385	1,507
29	chondrocyte	0.01	Nonsignificant	1.00	0.51	Other	548	1,069
30	schwann_cell	6.46e-03	Nonsignificant	1.00	0.46	Other	10	57
31	muscle_stem_cell	5.94e-03	Nonsignificant	1.00	0.46	Other	7	27
32	natural_killer_cell	5.56e-03	Nonsignificant	1.00	0.54	Other	1,204	2,052
33	T_cell	1.97e-03	Nonsignificant	1.00	0.26	Other	470	959
34	skeletal_muscle_cell	9.04e-06	Nonsignificant	1.00	0.28	Other	944	2,600

Subtype rankings — L1S (152)

Subtypes ranked by mean IC score
#	Cell population	Mean IC score	Significance	CSEA FDR	CSEA NES	Tier	Meta traits (Specific)	Individual traits (Specific)
1	IPSC.induced_pluripotent_stem_cell	89.55	Significant	—	—	Relevant	0	0
2	EPI.pancreatic_acinar	38.46	Significant	1.82e-15	1.26	Specific	429	1,475
3	ADIPO.adipocyte	31.30	Significant	—	—	Relevant	20	62
4	EPI.pancreatic_ductal_progenitor	22.93	Significant	0.28	1.18	Specific	234	873
5	HEP.periportal_metabolic	20.33	Significant	3.00e-50	2.42	Specific	1,750	4,427
6	EPI.pancreatic_ductal_perivascular	12.13	Significant	1.00	1.12	Relevant	4	30
7	NEU.INH_PVALB	11.85	Significant	0.25	1.44	—	193	183
8	NEU.EXC_CT	9.46	Significant	0.34	1.31	—	362	384
9	EPI.pancreatic_islet	9.21	Significant	1.00	1.11	Relevant	52	132
10	NEU.EXC_IT	9.07	Significant	0.60	1.07	—	411	192
11	NEU.EXC_SYT2	8.25	Significant	—	0.22	—	40	77
12	NEU.EXC_NTNG1	7.95	Significant	—	0.00	—	0	0
13	NEU.INH_VIP	7.33	Significant	0.67	0.98	—	241	366
14	HEP.acute_phase	5.97	Significant	1.00	0.56	Specific	1,441	3,641
15	MONO.CD14	5.13	Nominal	5.71e-21	2.37	Other	2,294	4,139
16	GRNLSA.granulosa_cell	4.25	Nominal	—	—	Other	257	0
17	HEP.canalicular_transport	4.11	Nominal	1.00	0.08	Other	1,290	3,434
18	EPI.pancreatic_ductal_mucinous	4.09	Nominal	1.00	1.05	Other	219	430
19	EPI.intrahepatic_cholangiocyte_transport	4.04	Nominal	—	0.76	Other	12	42
20	EPI.pancreatic_ductal_bicarbonate	3.82	Nominal	1.00	1.04	Other	131	548
21	HPC.haematopoietic_progenitor_cell	3.01	Nominal	—	—	Other	211	370
22	EC.liver_sinusoidal	2.99	Nonsignificant	4.77e-04	1.43	Other	1,083	1,925
23	PLAT.platelet	2.94	Nonsignificant	—	0.00	Other	38	53
24	MONO.CD16	2.69	Nonsignificant	1.00	0.18	Other	1,304	1,835
25	MEL.melanocyte	2.62	Nonsignificant	—	—	Other	79	242
26	HEP.pericentral_lipoprotein	2.44	Nonsignificant	—	0.00	Other	0	0
27	ASTRO.astrocyte	2.42	Nonsignificant	—	—	Other	228	1,111
28	NEU.INH_LAMP5	2.23	Nonsignificant	1.00	0.15	Other	263	532
29	EC.heart_remodeling	2.15	Nonsignificant	3.00e-03	1.21	Other	569	1,594
30	EC.lymphatic	2.02	Nonsignificant	7.72e-04	1.36	Other	630	998
31	DC.pDC	1.95	Nonsignificant	0.39	1.09	Other	496	1,028
32	EPI.renal_principal_cell	1.86	Nonsignificant	1.00	0.84	Other	207	403
33	EPI.colonic_enteroendocrine	1.63	Nonsignificant	—	0.77	Other	1	1
34	EPI.renal_distal_tubule	1.53	Nonsignificant	1.00	0.83	Other	133	361
35	EPI.skin_hair_follicle_companion	1.26	Nonsignificant	—	0.38	Other	8	12
36	OPC.oligodendrocyte_precursor_cell	1.26	Nonsignificant	—	—	Other	413	1,269
37	MAC.alveolar	1.22	Nonsignificant	7.06e-04	1.27	Other	1,432	3,122
38	EPI.ileal_goblet	1.15	Nonsignificant	1.00	0.84	Other	181	432
39	EPI.extrahepatic_cholangiocyte	1.14	Nonsignificant	—	0.56	Other	37	71
40	EPI.esophageal_suprabasal	1.11	Nonsignificant	1.00	0.79	Other	158	404
41	EPI.salivary_serous_acinar	1.10	Nonsignificant	1.00	0.91	Other	233	531
42	MAC.proliferating	1.02	Nonsignificant	0.85	1.10	Other	87	253
43	EC.arterial	0.87	Nonsignificant	0.37	1.04	Other	356	885
44	EPI.tracheal_basal	0.87	Nonsignificant	1.00	0.77	Other	398	1,120
45	SMC.smooth_muscle_cell	0.83	Nonsignificant	—	—	Other	20	101
46	EPI.colonocyte	0.83	Nonsignificant	1.00	0.70	Other	294	815
47	EPI.colonic_tuft	0.82	Nonsignificant	—	0.46	Other	7	24
48	MAC.kupffer	0.81	Nonsignificant	0.85	1.06	Other	189	530
49	EPI.gastric_foveolar	0.77	Nonsignificant	—	0.43	Other	0	0
50	FIB.neurolectin_mucosa	0.77	Nonsignificant	0.03	1.29	Other	133	394
51	EC.capillary	0.73	Nonsignificant	1.00	0.76	Other	514	1,635
52	EPI.ileal_enterocyte_absorptive	0.73	Nonsignificant	1.00	0.73	Other	118	338
53	FIB.suburothelial	0.71	Nonsignificant	9.13e-04	1.45	Other	122	432
54	FIB.skin_neurosecretory	0.69	Nonsignificant	—	1.39	Other	0	0
55	GRANU.neutrophil	0.63	Nonsignificant	1.90e-03	1.59	Other	1,235	2,649
56	EPI.esophageal_basal	0.63	Nonsignificant	1.00	0.75	Other	4	10
57	EPI.hepatic_ductular_cholangiocyte	0.60	Nonsignificant	1.00	0.64	Other	83	243
58	EPI.lung_club_secretory	0.55	Nonsignificant	1.00	0.82	Other	5	14
59	EPI.renal_thick_ascending_limb	0.53	Nonsignificant	1.00	0.64	Other	453	1,153
60	EPI.skin_keratinocyte_proliferating	0.52	Nonsignificant	1.00	0.84	Other	47	76
61	DC.cDC2	0.50	Nonsignificant	1.00	0.74	Other	1,189	1,793
62	T.CD4_Th2	0.47	Nonsignificant	—	2.78	Other	1	2
63	EPI.tracheal_submucosal_gland	0.46	Nonsignificant	—	0.18	Other	0	0
64	PC.IgG_systemic	0.45	Nonsignificant	0.02	1.35	Other	41	60
65	EPI.renal_intercalated_cell_type_A	0.45	Nonsignificant	1.00	0.52	Other	67	142
66	EPI.alveolar_type_1	0.42	Nonsignificant	1.00	0.69	Other	26	101
67	ILC2.innate_lymphoid_cell_2	0.40	Nonsignificant	—	—	Other	2	0
68	EPI.ileal_enterocyte_crypt	0.38	Nonsignificant	1.00	0.51	Other	67	113
69	B.germinal_center	0.37	Nonsignificant	6.79e-04	2.00	Other	233	655
70	EPI.salivary_mucous_acinar	0.37	Nonsignificant	1.00	0.60	Other	639	1,189
71	B.memory	0.29	Nonsignificant	6.79e-04	1.43	Other	442	882
72	EPI.tracheal_suprabasal	0.28	Nonsignificant	1.00	0.51	Other	29	56
73	FIB.adventitial	0.27	Nonsignificant	1.13e-04	1.24	Other	268	1,447
74	EC.venous	0.26	Nonsignificant	1.00	0.58	Other	516	1,387
75	EPI.lung_multiciliated	0.26	Nonsignificant	1.00	0.53	Other	16	49
76	THYMO.thymocyte	0.26	Nonsignificant	—	—	Other	163	495
77	EPI.skin_sweat_duct_keratinocyte	0.26	Nonsignificant	1.00	0.88	Other	146	301
78	MAC.LAM	0.24	Nonsignificant	1.00	1.01	Other	914	2,064
79	FIB.perivascular_interface	0.24	Nonsignificant	1.00	0.91	Other	0	0
80	EPI.renal_intercalated_cell_type_B	0.21	Nonsignificant	—	0.00	Other	6	7
81	B.naive	0.21	Nonsignificant	1.00	0.57	Other	307	595
82	EPI.intrahepatic_cholangiocyte_defense	0.21	Nonsignificant	—	0.00	Other	8	13
83	PC.IgA_muocsal	0.21	Nonsignificant	1.00	0.59	Other	18	31
84	EPI.skin_appendage_keratinocyte	0.20	Nonsignificant	1.00	0.43	Other	87	222
85	FIB.skin_sheath	0.20	Nonsignificant	1.00	0.83	Other	49	118
86	FIB.barrier_purinergic	0.16	Nonsignificant	—	0.39	Other	1	3
87	FIB.skin_papillary	0.14	Nonsignificant	—	0.30	Other	0	0
88	B.age_associated	0.14	Nonsignificant	1.00	0.35	Other	207	350
89	FIB.barrier_secretory	0.12	Nonsignificant	0.25	1.27	Other	81	228
90	MAC.resident_iron	0.11	Nonsignificant	1.00	0.81	Other	16	21
91	EPI.endocervical_secretory	0.10	Nonsignificant	—	0.00	Other	0	0
92	FIB.skin_tenogenic	0.10	Nonsignificant	—	0.13	Other	108	227
93	PERI.pericyte	0.09	Nonsignificant	—	—	Other	117	0
94	MESO.mesothelial_cell	0.09	Nonsignificant	—	—	Other	2	18
95	MG.microglia	0.08	Nonsignificant	—	—	Other	49	0
96	EPI.ectocervical_granular	0.08	Nonsignificant	—	0.00	Other	11	23
97	EPI.skin_hair_follicle_bulge	0.08	Nonsignificant	1.00	0.48	Other	51	178
98	ASPC.adipose_stem_and_progenitor_cell	0.07	Nonsignificant	—	—	Other	324	930
99	MAC.MDM	0.07	Nonsignificant	1.00	0.86	Other	623	986
100	EPI.renal_immature_ureteric_bud	0.07	Nonsignificant	1.00	0.33	Other	217	569
101	EPI.bile_duct_cholangiocyte	0.05	Nonsignificant	1.00	0.37	Other	37	60
102	GRANU.MAST	0.05	Nonsignificant	1.00	0.00	Other	5	6
103	FIB.tracheal_subepithelial	0.05	Nonsignificant	—	0.00	Other	0	0
104	FIB.interstitial	0.03	Nonsignificant	1.00	0.31	Other	288	940
105	EPI.salivary_myoepithelial	0.03	Nonsignificant	1.00	0.31	Other	191	714
106	CM.cardiomyocyte	0.02	Nonsignificant	—	—	Other	524	2,032
107	EPI.skin_follicular_keratinizing	0.02	Nonsignificant	1.00	0.32	Other	30	81
108	OLG.oligodendrocyte	0.02	Nonsignificant	—	—	Other	384	1,397
109	FIB.reticular	0.02	Nonsignificant	1.00	0.43	Other	19	87
110	FIB.lung_alveolar	0.01	Nonsignificant	—	0.00	Other	6	15
111	EPI.salivary_duct_ion_transport	0.01	Nonsignificant	1.00	0.36	Other	5	11
112	MAC.resident_cardiac	0.01	Nonsignificant	1.00	0.45	Other	485	1,074
113	MAC.resident_repair	0.01	Nonsignificant	1.00	0.58	Other	796	1,426
114	CHOND.chondrocyte	0.01	Nonsignificant	—	—	Other	519	730
115	EPI.skin_keratinocyte_progenitor	0.01	Nonsignificant	—	0.00	Other	0	3
116	FIB.transitioning	0.01	Nonsignificant	1.00	0.35	Other	172	497
117	DC.cDC1	9.57e-03	Nonsignificant	1.00	0.58	Other	55	112
118	EPI.salivary_intercalated_defense	6.62e-03	Nonsignificant	1.00	0.20	Other	81	161
119	T.CD4_transitional	6.60e-03	Nonsignificant	1.00	1.01	Other	48	110
120	SCHWN.schwann_cell	6.46e-03	Nonsignificant	—	—	Other	7	33
121	MAC.microglia_like	6.13e-03	Nonsignificant	1.00	0.51	Other	124	179
122	T.CD4_Treg	5.99e-03	Nonsignificant	1.00	1.02	Other	244	511
123	MUSC.muscle_stem_cell	5.94e-03	Nonsignificant	—	—	Other	4	18
124	NK.natural_killer_cell	5.56e-03	Nonsignificant	—	—	Other	1,204	2,045
125	EPI.ileal_bile_transport	5.55e-03	Nonsignificant	1.00	0.26	Other	61	93
126	FIB.hepatic_stellate_cell	5.22e-03	Nonsignificant	—	0.00	Other	64	252
127	T.CD8_transitional	3.64e-03	Nonsignificant	0.79	1.02	Other	497	932
128	T.CD8_Trm	3.10e-03	Nonsignificant	1.00	1.00	Other	211	346
129	EPI.skin_keratinocyte_basal	2.93e-03	Nonsignificant	—	0.00	Other	13	26
130	T.CD4_Tem	2.84e-03	Nonsignificant	0.79	1.04	Other	365	697
131	T.CD4_Trm	2.82e-03	Nonsignificant	1.00	1.00	Other	176	363
132	EPI.salivary_duct_excretory	1.73e-03	Nonsignificant	1.00	0.17	Other	85	180
133	T.CD4_Th17	1.63e-03	Nonsignificant	1.00	1.00	Other	421	794
134	EPI.renal_proximal_tubule	1.38e-03	Nonsignificant	1.00	0.20	Other	525	806
135	T.CD4_Tcm	9.93e-04	Nonsignificant	1.00	0.97	Other	494	988
136	DC.mig	8.17e-04	Nonsignificant	—	0.00	Other	89	156
137	T.CD4_Tfh	7.76e-04	Nonsignificant	1.00	0.98	Other	47	45
138	T.CD8_Tem	6.10e-04	Nonsignificant	0.79	1.02	Other	1,083	1,857
139	T.MAIT	6.01e-04	Nonsignificant	1.00	0.94	Other	469	855
140	EPI.skin_sebaceous_duct_luminal	5.95e-04	Nonsignificant	1.00	0.16	Other	100	249
141	EPI.cervical_suprabasal	4.41e-04	Nonsignificant	—	0.00	Other	14	50
142	T.CD4_naive	4.07e-04	Nonsignificant	1.00	0.96	Other	399	866
143	T.CD8_naive	3.26e-04	Nonsignificant	1.00	0.97	Other	317	708
144	T.CD8_Tcm	2.88e-04	Nonsignificant	1.00	0.92	Other	460	926
145	T.gamma_delta	2.86e-04	Nonsignificant	1.00	0.89	Other	588	1,078
146	EPI.thymic_medullary	1.88e-04	Nonsignificant	1.00	0.11	Other	26	133
147	EPI.thymic_cortical	1.55e-04	Nonsignificant	1.00	0.13	Other	442	824
148	EPI.skin_interfollicular_spinous	1.07e-04	Nonsignificant	1.00	0.11	Other	260	563
149	T.CD4_cytotoxic	6.88e-05	Nonsignificant	1.00	0.94	Other	855	1,493
150	EPI.alveolar_type_2	1.78e-05	Nonsignificant	1.00	0.03	Other	813	1,853
151	SKM.type_1_slow	1.16e-05	Nonsignificant	0.26	1.05	Other	923	2,478
152	SKM.type_2_fast	7.18e-06	Nonsignificant	0.47	1.01	Other	972	2,639

State rankings — L2 (688)

States ranked by mean IC score
#	Cell population	Mean IC score	Significance	CSEA FDR	CSEA NES	Tier	Meta traits (Specific)	Individual traits (Specific)
1	IPSC.mesendo_primed	134.98	Significant	2.46e-19	2.61	—	0	0
2	IPSC.stromal_primed	128.69	Significant	1.56e-08	2.21	—	0	0
3	IPSC.axial_identity_primed	97.39	Significant	0.23	1.29	—	0	0
4	IPSC.mesenchymal_primed	88.87	Significant	0.30	1.22	—	0	0
5	IPSC.proliferative	88.12	Significant	1.00	0.94	—	0	0
6	IPSC.neural_primed	62.20	Significant	1.00	0.38	—	0	0
7	IPSC.midbrain_primed	55.74	Significant	1.00	0.24	Relevant	0	0
8	EPI.pancreatic_acinar.quiet_dedifferentiation	52.64	Significant	6.29e-04	2.37	—	142	171
9	IPSC.stress	50.16	Significant	1.00	0.16	Relevant	0	0
10	EPI.pancreatic_acinar.baseline	49.27	Significant	7.24e-06	2.68	—	274	163
11	IPSC.canonical_pluripotent	41.95	Significant	1.00	0.07	—	0	0
12	ADIPO.inflammatory	41.46	Significant	—	0.59	Relevant	0	0
13	ADIPO.immature	40.32	Significant	—	0.44	—	24	40
14	EPI.pancreatic_acinar.metabolic_onecarbon	34.24	Significant	0.99	0.73	—	287	328
15	IPSC.endoderm_primed	33.05	Significant	1.00	0.03	Relevant	0	0
16	EPI.pancreatic_acinar.adhesion_remodeling	32.38	Significant	0.99	0.49	Relevant	210	784
17	ADIPO.hypoxia_remodelling	31.43	Significant	—	0.22	Relevant	29	105
18	HEP.periportal_metabolic.xenobiotic_detox	28.14	Significant	1.27e-03	1.98	—	1,440	139
19	HEP.periportal_metabolic.canonical_urea_cycle	25.94	Significant	8.01e-04	2.06	—	1,464	269
20	EPI.pancreatic_ductal_progenitor.ciliated_transport	25.41	Significant	—	0.53	Relevant	105	368
21	EPI.pancreatic_acinar.stress	24.94	Significant	0.99	0.19	—	28	28
22	EPI.pancreatic_ductal_progenitor.baseline	24.16	Significant	0.15	1.51	Relevant	179	702
23	HEP.periportal_metabolic.urea_onecarbon_secretory	20.56	Significant	1.00	0.93	Specific	1,332	3,053
24	IPSC.neuroendocrine_primed	20.38	Significant	—	0.00	—	0	0
25	EPI.pancreatic_ductal_progenitor.ADM_like	20.20	Significant	—	0.00	—	0	0
26	NEU.EXC_CT.Ca2_sensor	20.05	Significant	—	1.44	—	0	0
27	EPI.pancreatic_acinar.inflammatory_regenerative	19.92	Significant	0.99	0.56	Relevant	25	113
28	NEU.INH_PVALB.neuromodulatory	18.50	Significant	—	1.94	—	0	0
29	HEP.periportal_metabolic.inflammatory_activated	18.26	Significant	1.00	0.62	Specific	712	1,610
30	EPI.pancreatic_ductal_perivascular.protective_antioxidant	16.17	Significant	—	0.85	Relevant	11	69
31	HEP.periportal_metabolic.apolipoprotein_secretory	15.88	Significant	1.00	0.91	Relevant	43	110
32	NEU.INH_PVALB.nuclear_reg	14.02	Significant	0.12	1.76	—	25	12
33	NEU.INH_VIP.canonical_disinhibitory	13.60	Significant	0.08	1.44	—	59	38
34	NEU.EXC_IT.adhesion	13.56	Significant	8.56e-03	1.88	—	252	108
35	NEU.INH_PVALB.fastspike	13.21	Significant	—	0.38	—	24	22
36	HEP.periportal_metabolic.stress_chaperone	13.18	Significant	—	0.00	Relevant	66	128
37	ADIPO.thermogenic	13.05	Significant	—	0.00	—	0	0
38	EPI.pancreatic_islet.delta	12.95	Significant	—	0.67	Relevant	0	0
39	HEP.periportal_metabolic.acute_phase_barrier	12.85	Significant	1.00	0.15	—	533	138
40	NEU.EXC_SYT2.synaptic	12.59	Significant	—	0.48	—	0	0
41	NEU.INH_PVALB.serotonergic	12.54	Significant	—	0.21	—	0	0
42	EPI.pancreatic_ductal_progenitor.biliary_like_xenobiotic	12.33	Significant	—	0.00	—	0	0
43	IPSC.mesodermal_primed	12.28	Significant	1.00	5.09e-03	—	0	0
44	NEU.EXC_CT.remodeling	11.15	Significant	—	0.27	—	23	1
45	NEU.EXC_IT.transitional	11.11	Significant	0.32	1.43	—	237	142
46	NEU.INH_VIP.serotonergic	10.91	Significant	—	0.56	—	9	2
47	NEU.INH_VIP.opioid	10.52	Significant	—	0.58	—	50	9
48	EPI.salivary_serous_acinar.seromucous_like	9.97	Significant	—	1.75	Relevant	0	0
49	EPI.salivary_serous_acinar.quiescent	9.96	Significant	4.38e-04	1.52	Specific	178	493
50	EPI.pancreatic_islet.beta	9.60	Significant	0.38	1.21	—	42	57
51	NEU.INH_VIP.excitatory_coupled	9.57	Significant	—	0.41	—	13	0
52	EPI.pancreatic_ductal_perivascular.baseline	9.57	Significant	1.00	0.00	Relevant	1	5
53	NEU.INH_VIP.regulatory_remodeling	9.30	Significant	—	0.36	—	6	1
54	NEU.EXC_IT.guidance	9.26	Significant	0.71	1.13	—	274	63
55	NEU.EXC_NTNG1.nuclear_reg	8.84	Significant	—	0.67	—	0	0
56	NEU.EXC_IT.structural	8.45	Significant	0.76	0.98	—	171	41
57	NEU.INH_PVALB.chandelier	8.22	Significant	1.00	0.00	—	19	16
58	HEP.acute_phase.complement_metabolic	8.07	Significant	5.22e-07	2.63	Specific	1,423	3,464
59	EPI.pancreatic_islet.alpha	7.85	Significant	—	0.00	—	152	330
60	NEU.INH_PVALB.metabotropic	7.66	Significant	—	0.00	—	0	0
61	NEU.EXC_IT.callosal	7.54	Significant	1.00	0.52	—	286	119
62	GRNLSA.EMT_insulin_signaling	7.44	Significant	0.30	1.52	Relevant	47	84
63	NEU.EXC_CT.projector	6.98	Significant	0.92	0.41	—	87	26
64	NEU.EXC_NTNG1.synaptic	6.93	Significant	—	0.00	—	0	0
65	GRNLSA.p53_damage	6.83	Significant	—	0.62	Relevant	13	10
66	HPC.MEP	6.81	Significant	0.23	1.37	Other	599	1,195
67	EPI.intrahepatic_cholangiocyte_transport.protease_shield_hippo	6.65	Significant	—	0.73	Relevant	0	0
68	MONO.CD14.remodeling	6.59	Significant	7.75e-07	1.83	Specific	2,373	295
69	HEP.acute_phase.proliferative	6.32	Significant	—	0.34	Relevant	4	6
70	EPI.pancreatic_ductal_bicarbonate.renewal_ion_pump	6.17	Significant	0.18	1.68	Relevant	40	191
71	MONO.CD14.cord_tolerance	6.06	Significant	0.79	1.10	Relevant	864	753
72	GRNLSA.angiocrine_mechanosensory	5.80	Significant	—	0.46	Relevant	0	0
73	EPI.pancreatic_ductal_mucinous.proliferative_gastric_like	5.78	Significant	—	0.81	Relevant	0	0
74	NEU.EXC_CT.Ca2_signaling	5.64	Significant	—	0.00	—	68	17
75	GRNLSA.cholesterol_mevalonate	5.47	Nominal	0.56	1.29	Other	9	4
76	HEP.canalicular_transport.secretory_ERAD_UPR	5.45	Nominal	1.97e-05	2.78	Other	232	28
77	HEP.periportal_metabolic.stress_checkpoint	5.41	Nominal	1.00	0.00	Other	234	786
78	EPI.pancreatic_ductal_mucinous.remodeling_channel_rich	5.35	Nominal	—	0.55	Other	0	0
79	HEP.acute_phase.complement_antiviral	5.28	Nominal	1.00	0.86	Other	377	751
80	HEP.acute_phase.baseline	5.20	Nominal	1.00	0.22	Other	946	19
81	MONO.CD14.platelet_bound	5.19	Nominal	0.15	1.47	Other	964	176
82	MONO.CD14.baseline	5.01	Nominal	1.00	0.75	Other	2,268	76
83	GRNLSA.lipid_hypoxia	4.94	Nominal	0.81	0.88	Other	28	0
84	EC.heart_remodeling.remodeling_secretory	4.78	Nominal	1.87e-04	1.64	Other	605	1,341
85	HEP.canalicular_transport.baseline	4.71	Nominal	0.07	1.88	Other	199	477
86	MONO.CD16.inflammatory	4.69	Nominal	8.43e-06	1.71	Other	1,640	168
87	MONO.CD14.APC_like	4.54	Nominal	1.00	0.50	Other	1,686	2,493
88	HEP.canalicular_transport.ductular_like_transition	4.52	Nominal	0.07	1.86	Other	400	87
89	MEL.mature_oxidative_traffic	4.46	Nominal	9.09e-07	2.30	Other	247	285
90	HEP.acute_phase.inflammatory	4.38	Nominal	1.00	0.17	Other	382	649
91	NEU.INH_VIP.nuclear_reg	4.36	Nominal	—	0.00	Other	20	4
92	EPI.pancreatic_ductal_bicarbonate.baseline	4.31	Nominal	0.44	1.13	Other	11	42
93	EPI.pancreatic_ductal_mucinous.mucin_rich_barrier	4.30	Nominal	0.64	0.84	Other	449	1,034
94	HEP.canalicular_transport.sterol_lipid_biosynthesis	4.20	Nominal	—	0.24	Other	10	20
95	EPI.intrahepatic_cholangiocyte_transport.mucin_secretory	4.17	Nominal	—	0.00	Other	0	0
96	HEP.acute_phase.stress_secretory	4.09	Nominal	1.00	0.18	Other	26	3
97	NEU.EXC_IT.neuromodulated	4.07	Nominal	1.00	0.04	Other	176	116
98	GRNLSA.stress_metabolic	4.05	Nominal	—	0.00	Other	1	2
99	EPI.pancreatic_ductal_bicarbonate.activated	4.03	Nominal	0.44	1.09	Other	10	7
100	EC.liver_sinusoidal.remodeling_lipotoxicity	4.00	Nominal	—	0.95	Other	90	58
101	HEP.canalicular_transport.injury_stress	3.86	Nominal	0.97	0.80	Other	289	24
102	GRNLSA.secretory_remodeling	3.80	Nominal	0.69	1.11	Other	90	25
103	HEP.canalicular_transport.inflammatory	3.79	Nominal	0.97	0.44	Other	1,335	194
104	EC.liver_sinusoidal.hypoxia_metabolic	3.79	Nominal	0.03	1.94	Other	183	107
105	HEP.acute_phase.hypoxia_lipid	3.74	Nominal	—	0.00	Other	0	0
106	HEP.canalicular_transport.pericentral_like_hypoxia	3.58	Nominal	0.97	0.34	Other	326	8
107	EPI.pancreatic_ductal_bicarbonate.barrier_mucin	3.54	Nominal	0.44	1.05	Other	219	533
108	ASTRO.neuromodulatory	3.51	Nominal	3.63e-03	2.01	Other	34	172
109	EC.liver_sinusoidal.stress	3.40	Nominal	—	0.26	Other	413	158
110	EPI.pancreatic_ductal_bicarbonate.junctional_remodel	3.30	Nominal	—	0.00	Other	49	237
111	EPI.renal_distal_tubule.ion_transport	3.19	Nominal	—	0.86	Other	0	0
112	ASTRO.stress_acute	3.15	Nominal	0.31	1.46	Other	60	56
113	PLAT.adhesion	3.10	Nominal	—	0.48	Other	0	0
114	MONO.CD16.hepatic_mac_like	3.04	Nominal	0.09	1.33	Other	803	117
115	EPI.renal_principal_cell.injury_repair	3.03	Nominal	0.12	1.71	Other	26	9
116	MONO.CD16.platelet_bound	2.99	Nonsignificant	0.36	1.24	Other	372	508
117	EPI.esophageal_suprabasal.proliferative_G2M	2.90	Nonsignificant	—	2.10	Other	0	0
118	HPC.GMP_granulocytic	2.87	Nonsignificant	—	0.25	Other	3	3
119	MEL.dedifferentiated_migratory	2.85	Nonsignificant	—	0.26	Other	0	0
120	NEU.INH_LAMP5.exc_inh_balance	2.84	Nonsignificant	—	0.94	Other	46	2
121	MONO.CD16.baseline	2.78	Nonsignificant	0.57	1.03	Other	50	1
122	EC.arterial.angiogenic_tip	2.70	Nonsignificant	—	1.56	Other	30	37
123	PLAT.megakaryocytic	2.66	Nonsignificant	—	0.00	Other	0	0
124	HPC.LMPP	2.65	Nonsignificant	0.75	1.12	Other	65	31
125	ASTRO.homeostatic	2.63	Nonsignificant	0.50	1.16	Other	200	431
126	EPI.skin_hair_follicle_companion.gap_junction_contractile	2.60	Nonsignificant	—	0.97	Other	0	0
127	ASTRO.stress_mito	2.59	Nonsignificant	0.78	0.90	Other	47	110
128	ASTRO.immature_lipid	2.58	Nonsignificant	0.64	1.06	Other	23	113
129	EPI.renal_distal_tubule.repair	2.57	Nonsignificant	—	0.55	Other	34	102
130	GRNLSA.chemokine_mechanosensory	2.57	Nonsignificant	0.85	0.67	Other	1	0
131	ASTRO.A1_reactive	2.56	Nonsignificant	0.50	1.19	Other	433	394
132	EC.heart_remodeling.remodeling_stalk	2.52	Nonsignificant	1.00	0.97	Other	33	111
133	DC.pDC.baseline	2.50	Nonsignificant	0.78	0.99	Other	88	123
134	HEP.pericentral_lipoprotein.UPR_redox	2.48	Nonsignificant	—	0.67	Other	0	0
135	EC.liver_sinusoidal.inflammatory	2.44	Nonsignificant	—	0.00	Other	223	154
136	HEP.pericentral_lipoprotein.ApoB_coagulation	2.41	Nonsignificant	—	0.00	Other	0	0
137	EPI.pancreatic_ductal_bicarbonate.repair_actin_junction	2.41	Nonsignificant	—	0.00	Other	0	0
138	EPI.pancreatic_ductal_bicarbonate.stress	2.41	Nonsignificant	—	0.00	Other	12	33
139	THYMO.proliferative_S	2.35	Nonsignificant	0.40	1.12	Other	163	418
140	DC.pDC.immature_metabolic	2.32	Nonsignificant	0.29	1.35	Other	78	124
141	EPI.renal_principal_cell.intercalated_like	2.30	Nonsignificant	0.57	1.32	Other	63	66
142	EC.lymphatic.scavenger	2.28	Nonsignificant	0.14	1.96	Other	203	257
143	NEU.INH_VIP.enkephalinergic	2.26	Nonsignificant	—	0.00	Other	0	0
144	EC.capillary.angiogenic_tip	2.18	Nonsignificant	9.94e-03	1.61	Other	186	218
145	EC.liver_sinusoidal.secretory_lipoprotein	2.09	Nonsignificant	0.97	0.26	Other	120	70
146	EPI.colonic_enteroendocrine.enterochromaffin_serotonin	2.07	Nonsignificant	—	0.97	Other	0	0
147	EC.liver_sinusoidal.prostanoid	2.07	Nonsignificant	—	0.00	Other	11	64
148	EC.lymphatic.baseline	2.04	Nonsignificant	0.85	0.74	Other	38	72
149	EC.lymphatic.tip_migratory	2.02	Nonsignificant	0.85	0.58	Other	23	37
150	NEU.INH_LAMP5.glial_interface	2.00	Nonsignificant	—	0.00	Other	0	0
151	DC.cDC2.monocyte_like	1.97	Nonsignificant	0.31	1.14	Other	1,285	791
152	NEU.INH_LAMP5.rosehip	1.97	Nonsignificant	—	0.00	Other	0	0
153	EC.heart_remodeling.perivascular	1.94	Nonsignificant	1.00	1.00	Other	124	408
154	EC.lymphatic.activated	1.80	Nonsignificant	0.85	0.52	Other	47	73
155	MAC.alveolar.biosynthetic_sterol_heme	1.79	Nonsignificant	0.59	1.33	Other	347	40
156	ASTRO.hypoxia_angiogenic	1.79	Nonsignificant	0.50	1.30	Other	5	18
157	EPI.skin_sweat_duct_keratinocyte.proliferative_G2M	1.78	Nonsignificant	—	1.52	Other	0	0
158	MAC.kupffer.monocyte_like	1.77	Nonsignificant	—	0.70	Other	0	0
159	MEL.stress_glucocorticoid	1.76	Nonsignificant	1.00	0.24	Other	11	34
160	EPI.hepatic_ductular_cholangiocyte.acute_phase_complement	1.75	Nonsignificant	—	1.22	Other	0	0
161	EPI.esophageal_suprabasal.proliferative_S	1.75	Nonsignificant	—	1.16	Other	26	41
162	EPI.renal_thick_ascending_limb.salt_sensing	1.68	Nonsignificant	0.05	1.49	Other	73	103
163	SMC.contractile	1.68	Nonsignificant	2.84e-03	1.45	Other	80	588
164	HPC.MPP_activated	1.64	Nonsignificant	—	0.22	Other	0	0
165	OPC.homeostatic	1.61	Nonsignificant	6.16e-04	2.22	Other	394	160
166	MEL.secretory_quiescent	1.60	Nonsignificant	1.00	0.13	Other	19	13
167	EC.arterial.arteriole_gas_exchange	1.56	Nonsignificant	1.44e-03	1.42	Other	238	131
168	EPI.pancreatic_ductal_bicarbonate.inflammatory	1.55	Nonsignificant	0.44	1.21	Other	14	32
169	EC.lymphatic.valve	1.53	Nonsignificant	—	0.00	Other	0	0
170	EPI.skin_keratinocyte_proliferating.detox_repair	1.52	Nonsignificant	—	0.55	Other	0	0
171	EC.arterial.ion_pump	1.51	Nonsignificant	0.55	1.18	Other	3	2
172	EPI.extrahepatic_cholangiocyte.mucin_secretory	1.51	Nonsignificant	—	0.42	Other	0	0
173	EPI.renal_principal_cell.activated_acute	1.50	Nonsignificant	0.82	0.81	Other	29	59
174	NEU.INH_VIP.cannabinoid	1.49	Nonsignificant	—	0.00	Other	0	0
175	ASTRO.A2_reactive	1.47	Nonsignificant	1.00	0.12	Other	10	37
176	MAC.alveolar.scavenging_endocytic	1.47	Nonsignificant	—	0.15	Other	140	283
177	NEU.INH_LAMP5.projecting	1.47	Nonsignificant	—	0.00	Other	0	0
178	ASTRO.synaptic_interaction	1.45	Nonsignificant	1.00	0.05	Other	76	334
179	EPI.colonic_enteroendocrine.Lcell_peptide	1.45	Nonsignificant	—	0.00	Other	0	0
180	EPI.renal_principal_cell.canonical_vasopressin	1.45	Nonsignificant	0.82	0.85	Other	2	0
181	MAC.alveolar.stress_metabolic	1.45	Nonsignificant	1.00	0.89	Other	116	148
182	EC.venous.remodeling_stalk	1.40	Nonsignificant	0.03	1.38	Other	559	566
183	GRNLSA.proliferative_migratory	1.38	Nonsignificant	0.81	0.90	Other	248	292
184	MAC.alveolar.lipid_autophagy	1.37	Nonsignificant	—	0.29	Other	35	44
185	EPI.colonic_enteroendocrine.progenitor	1.37	Nonsignificant	—	0.00	Other	0	0
186	EPI.ileal_enterocyte_absorptive.brush_border	1.35	Nonsignificant	7.16e-07	1.72	Other	580	1,717
187	HPC.GMP_inflammatory	1.35	Nonsignificant	0.93	0.55	Other	20	10
188	EPI.ileal_goblet.baseline	1.31	Nonsignificant	0.22	1.63	Other	16	2
189	EPI.ileal_goblet.stress_metallothionein	1.29	Nonsignificant	—	0.10	Other	4	11
190	EC.arterial.mito_contact	1.29	Nonsignificant	0.24	1.28	Other	14	5
191	NEU.EXC_SYT2.nuclear_reg	1.29	Nonsignificant	—	0.00	Other	0	0
192	EPI.renal_intercalated_cell_type_A.PC_transitional	1.25	Nonsignificant	—	0.64	Other	203	407
193	NEU.INH_VIP.matrix	1.24	Nonsignificant	—	0.00	Other	24	77
194	OPC.proliferative_immune_interact	1.23	Nonsignificant	0.98	0.80	Other	180	373
195	THYMO.proliferative_G2M	1.22	Nonsignificant	—	1.46	Other	164	413
196	EC.capillary.inflammatory	1.17	Nonsignificant	0.67	1.14	Other	27	51
197	EC.venous.quiescent_homeostatic	1.13	Nonsignificant	0.16	1.24	Other	456	360
198	EPI.esophageal_suprabasal.basal_transitional	1.12	Nonsignificant	0.52	1.32	Other	44	67
199	EPI.ileal_enterocyte_crypt.proliferative_G2M	1.11	Nonsignificant	—	1.23	Other	19	54
200	EPI.lung_club_secretory.ciliogenesis_primed	1.10	Nonsignificant	—	1.47	Other	0	0
201	MAC.kupffer.stress	1.10	Nonsignificant	0.14	1.40	Other	9	3
202	ILC2.quiescent	1.10	Nonsignificant	—	0.35	Other	0	0
203	T.CD4_Th2.tissue_adapted	1.08	Nonsignificant	—	0.97	Other	0	0
204	EPI.colonocyte.junction_remodeling	1.07	Nonsignificant	0.02	1.92	Other	218	305
205	MONO.CD16.patrolling	1.05	Nonsignificant	1.00	0.15	Other	797	216
206	EPI.skin_hair_follicle_companion.bulge_anchor_signaling	1.05	Nonsignificant	—	0.00	Other	0	0
207	EPI.hepatic_ductular_cholangiocyte.secretory_transport	1.05	Nonsignificant	—	1.16	Other	0	0
208	HPC.MPP_IEG	1.05	Nonsignificant	0.93	0.47	Other	45	46
209	MAC.proliferating.DNA_replication	1.05	Nonsignificant	0.47	1.08	Other	3	6
210	EPI.ileal_goblet.inflammatory_mucin	1.03	Nonsignificant	0.58	0.88	Other	6	9
211	EC.arterial.arteriole_interface	1.03	Nonsignificant	0.75	1.05	Other	31	12
212	MEL.neurotrophic_migratory	1.02	Nonsignificant	—	0.00	Other	0	0
213	MAC.alveolar.inflammatory	0.98	Nonsignificant	1.00	0.76	Other	208	312
214	MAC.proliferating.stress	0.97	Nonsignificant	—	0.00	Other	87	136
215	EPI.colonic_tuft.activated	0.97	Nonsignificant	—	0.42	Other	0	0
216	EPI.tracheal_basal.homeostatic_progenitor	0.96	Nonsignificant	0.26	1.55	Other	285	74
217	EPI.colonocyte.ionocyte_BEST4	0.96	Nonsignificant	0.35	1.45	Other	103	188
218	EC.heart_remodeling.capillary_metabolic	0.95	Nonsignificant	1.00	0.46	Other	54	414
219	EPI.renal_distal_tubule.ciliated_remodelling	0.92	Nonsignificant	—	0.00	Other	0	0
220	DC.pDC.poised_migratory	0.92	Nonsignificant	0.97	0.44	Other	54	95
221	OPC.premyelinating	0.90	Nonsignificant	0.98	0.20	Other	185	12
222	EPI.esophageal_suprabasal.differentiating_keratin	0.90	Nonsignificant	0.99	0.10	Other	131	61
223	EPI.colonocyte.secretory_boost	0.89	Nonsignificant	0.73	0.92	Other	98	91
224	EPI.colonocyte.goblet_interface	0.88	Nonsignificant	—	0.27	Other	11	21
225	FIB.neurolectin_mucosa.axon_responsive	0.86	Nonsignificant	0.61	1.19	Other	10	10
226	MAC.kupffer.fibrogenic	0.85	Nonsignificant	—	0.37	Other	0	0
227	FIB.neurolectin_mucosa.inflammatory	0.82	Nonsignificant	0.61	0.89	Other	52	110
228	FIB.suburothelial.homeostasis_matrix	0.81	Nonsignificant	0.07	2.03	Other	258	921
229	EPI.colonocyte.crypt_progenitor	0.81	Nonsignificant	0.73	0.98	Other	115	265
230	ASPC.mesothelial_like	0.79	Nonsignificant	0.08	1.47	Other	143	486
231	EC.heart_remodeling.activated_acute	0.79	Nonsignificant	1.00	0.47	Other	102	186
232	CM.contractile_oxphos	0.78	Nonsignificant	0.40	1.13	Other	6	19
233	DC.cDC2.migratory	0.78	Nonsignificant	0.69	1.07	Other	185	39
234	EPI.gastric_foveolar.baseline	0.77	Nonsignificant	—	0.00	Other	0	0
235	GRANU.neutrophil.antiviral_endotoxin	0.77	Nonsignificant	—	0.90	Other	0	0
236	EPI.esophageal_suprabasal.proliferative_exit	0.77	Nonsignificant	—	0.00	Other	0	0
237	EPI.hepatic_ductular_cholangiocyte.polarity	0.77	Nonsignificant	—	0.43	Other	0	0
238	FIB.suburothelial.inflammatory_prostanoid	0.76	Nonsignificant	—	0.54	Other	0	0
239	EPI.renal_thick_ascending_limb.canonical_salt_transporter	0.75	Nonsignificant	0.32	1.20	Other	322	317
240	EC.capillary.baseline	0.75	Nonsignificant	0.67	1.07	Other	246	560
241	EPI.extrahepatic_cholangiocyte.barrier_interface	0.75	Nonsignificant	—	0.00	Other	0	0
242	EPI.tracheal_basal.activated_stress	0.73	Nonsignificant	1.00	0.00	Other	32	0
243	MAC.kupffer.tolerogenic	0.73	Nonsignificant	—	0.22	Other	45	49
244	PC.IgG_systemic.metabolic	0.72	Nonsignificant	0.19	1.47	Other	46	63
245	FIB.suburothelial.contractile_myofibroblast	0.71	Nonsignificant	—	0.08	Other	9	0
246	EPI.renal_principal_cell.inflammatory	0.71	Nonsignificant	1.00	0.04	Other	74	157
247	FIB.neurolectin_mucosa.nerve_interface	0.70	Nonsignificant	—	0.00	Other	4	0
248	EPI.lung_club_secretory.canonical_surfactant	0.70	Nonsignificant	—	0.26	Other	74	104
249	ASPC.signal_integrator	0.69	Nonsignificant	—	1.60	Other	0	0
250	FIB.skin_neurosecretory.baseline	0.69	Nonsignificant	—	0.00	Other	0	0
251	FIB.neurolectin_mucosa.remodeling_repair	0.67	Nonsignificant	—	0.00	Other	4	2
252	EC.venous.cardiac_structural	0.67	Nonsignificant	0.26	1.28	Other	102	229
253	EPI.colonic_tuft.homeostatic	0.67	Nonsignificant	—	0.00	Other	0	0
254	EPI.esophageal_basal.activated_progenitor	0.65	Nonsignificant	0.61	0.96	Other	1	0
255	FIB.adventitial.mechano_chemo_sensing	0.64	Nonsignificant	3.21e-03	1.50	Other	135	524
256	EPI.tracheal_submucosal_gland.ductal_luminal	0.63	Nonsignificant	—	0.73	Other	0	0
257	EPI.hepatic_ductular_cholangiocyte.stress	0.63	Nonsignificant	—	0.40	Other	0	0
258	FIB.suburothelial.urothelial_interface	0.62	Nonsignificant	1.00	0.00	Other	9	8
259	EPI.renal_distal_tubule.immune_modulatory	0.62	Nonsignificant	—	0.00	Other	0	0
260	B.germinal_center.LZ_selection	0.62	Nonsignificant	—	0.73	Other	0	0
261	EC.arterial.inflammatory	0.59	Nonsignificant	1.00	0.87	Other	63	50
262	EPI.colonocyte.proximal_transport	0.58	Nonsignificant	0.94	0.47	Other	24	12
263	EC.heart_remodeling.angiocrine	0.58	Nonsignificant	1.00	0.05	Other	182	525
264	GRANU.neutrophil.tissue_patrolling	0.57	Nonsignificant	—	0.00	Other	0	0
265	PC.IgA_muocsal.plasmablast	0.57	Nonsignificant	0.08	1.42	Other	5	4
266	PC.IgG_systemic.interacting	0.56	Nonsignificant	0.34	1.30	Other	0	0
267	EPI.esophageal_basal.junctional_barrier	0.56	Nonsignificant	—	0.00	Other	0	0
268	EC.heart_remodeling.translation_boost	0.55	Nonsignificant	—	0.00	Other	0	0
269	B.germinal_center.LZ_survival	0.54	Nonsignificant	—	0.79	Other	0	0
270	B.germinal_center.LZ_memory_precursor	0.54	Nonsignificant	—	0.37	Other	0	0
271	EPI.ileal_goblet.immature	0.54	Nonsignificant	—	0.00	Other	0	0
272	EPI.skin_appendage_keratinocyte.sebaceous_apocrine	0.53	Nonsignificant	—	0.89	Other	39	82
273	GRANU.neutrophil.primed_degranulation	0.53	Nonsignificant	—	0.00	Other	0	0
274	EC.capillary.migratory	0.52	Nonsignificant	1.00	0.74	Other	181	509
275	EPI.pancreatic_ductal_mucinous.xenobiotic_ERexit	0.52	Nonsignificant	—	0.00	Other	0	0
276	EPI.ectocervical_granular.inflammatory	0.51	Nonsignificant	—	1.15	Other	0	0
277	EPI.renal_thick_ascending_limb.cation_flux	0.50	Nonsignificant	1.00	0.90	Other	57	95
278	EC.capillary.stress	0.50	Nonsignificant	1.00	0.80	Other	44	36
279	EC.capillary.activated	0.47	Nonsignificant	0.67	1.17	Other	2	5
280	PC.IgG_systemic.stress	0.44	Nonsignificant	—	0.07	Other	1	5
281	MAC.LAM.antimicrobial	0.44	Nonsignificant	0.22	1.19	Other	389	93
282	EPI.alveolar_type_1.baseline	0.43	Nonsignificant	0.10	1.84	Other	8	0
283	EPI.lung_multiciliated.mature_motile_cilia	0.43	Nonsignificant	—	1.53	Other	0	0
284	EPI.ileal_enterocyte_crypt.secretory_precursor	0.42	Nonsignificant	—	0.31	Other	0	0
285	EC.capillary.angiocrine	0.42	Nonsignificant	1.00	0.61	Other	250	630
286	EPI.colonocyte.distal_absorptive	0.42	Nonsignificant	—	0.00	Other	0	0
287	EPI.tracheal_suprabasal.transitional_wound	0.39	Nonsignificant	—	0.43	Other	16	1
288	EPI.lung_club_secretory.ciliogenesis_axoneme	0.39	Nonsignificant	—	0.00	Other	0	0
289	FIB.adventitial.mito_secretory	0.39	Nonsignificant	1.00	1.03	Other	21	7
290	NEU.INH_VIP.LAMP5_hybrid	0.37	Nonsignificant	—	0.00	Other	1	9
291	EPI.hepatic_ductular_cholangiocyte.mechanosense_adhesion	0.37	Nonsignificant	—	0.00	Other	5	3
292	SMC.activated	0.37	Nonsignificant	0.99	0.58	Other	2	5
293	EPI.salivary_mucous_acinar.baseline	0.37	Nonsignificant	—	—	Other	394	683
294	MAC.alveolar.capillary_interacting	0.36	Nonsignificant	1.00	0.24	Other	113	181
295	B.memory.migratory	0.36	Nonsignificant	0.32	1.28	Other	123	208
296	EPI.ileal_enterocyte_crypt.proliferative_S	0.36	Nonsignificant	0.79	1.13	Other	4	2
297	SMC.metabolic	0.35	Nonsignificant	0.99	0.58	Other	14	40
298	EPI.ileal_enterocyte_crypt.baseline	0.35	Nonsignificant	0.79	1.01	Other	11	6
299	EC.arterial.metabolic	0.35	Nonsignificant	1.00	0.54	Other	195	159
300	HPC.CLP_B_primed	0.34	Nonsignificant	—	0.00	Other	0	0
301	FIB.skin_sheath.neuro_vascular_interface	0.34	Nonsignificant	—	1.03	Other	0	0
302	FIB.adventitial.complement_angiocrine	0.33	Nonsignificant	1.00	1.08	Other	153	684
303	FIB.perivascular_interface.vascular_BM_remodelling	0.33	Nonsignificant	—	0.64	Other	0	0
304	EPI.hepatic_ductular_cholangiocyte.barrier_chemokine	0.33	Nonsignificant	—	0.00	Other	6	9
305	MONO.CD14.repair_M2_like	0.32	Nonsignificant	1.00	0.01	Other	550	1,495
306	B.memory.pDC_imprint	0.32	Nonsignificant	0.53	1.18	Other	157	103
307	EPI.alveolar_type_1.activated	0.32	Nonsignificant	—	0.00	Other	0	0
308	EPI.skin_hair_follicle_bulge.niche_crosstalk	0.32	Nonsignificant	—	1.32	Other	29	88
309	B.memory.baseline	0.32	Nonsignificant	0.19	1.39	Other	472	99
310	EC.capillary.postcap_venule	0.31	Nonsignificant	1.00	0.46	Other	355	261
311	EPI.intrahepatic_cholangiocyte_defense.secretory_barrier	0.31	Nonsignificant	—	0.73	Other	0	0
312	B.naive.remodeling	0.30	Nonsignificant	0.12	1.51	Other	135	230
313	DC.cDC2.adhesion_signaling	0.29	Nonsignificant	0.99	0.97	Other	35	9
314	EPI.lung_multiciliated.stress	0.28	Nonsignificant	—	0.16	Other	67	165
315	EPI.tracheal_submucosal_gland.acinar_serous	0.28	Nonsignificant	—	0.00	Other	0	0
316	MAC.LAM.inflammatory_APC	0.27	Nonsignificant	0.21	1.19	Other	872	165
317	MESO.activated_migratory	0.27	Nonsignificant	—	0.56	Other	0	0
318	PERI.baseline	0.26	Nonsignificant	2.99e-03	1.30	Other	39	66
319	ASPC.proliferative	0.26	Nonsignificant	0.31	1.35	Other	33	85
320	B.naive.receptor_recycle	0.25	Nonsignificant	0.73	1.12	Other	51	0
321	B.naive.proteostasis	0.25	Nonsignificant	0.69	1.25	Other	49	69
322	DC.cDC2.proliferative	0.25	Nonsignificant	—	0.34	Other	39	71
323	FIB.perivascular_interface.vasomotor_tone	0.25	Nonsignificant	—	0.00	Other	0	0
324	EC.arterial.homeostatic	0.25	Nonsignificant	1.00	0.26	Other	24	3
325	EPI.skin_appendage_keratinocyte.transit_amplifying	0.24	Nonsignificant	—	0.69	Other	109	358
326	B.naive.antigen_presenting_ready	0.24	Nonsignificant	0.73	1.17	Other	48	73
327	PC.IgA_muocsal.migratory	0.24	Nonsignificant	0.32	1.10	Other	4	1
328	MAC.resident_iron.redox_metabolic	0.24	Nonsignificant	0.30	1.32	Other	4	4
329	EPI.renal_distal_tubule.stress	0.23	Nonsignificant	—	0.00	Other	0	0
330	MAC.kupffer.metabolic	0.23	Nonsignificant	—	0.00	Other	25	36
331	MAC.kupffer.inflammatory	0.23	Nonsignificant	—	0.00	Other	7	4
332	FIB.adventitial.baseline	0.23	Nonsignificant	1.00	0.97	Other	157	278
333	MAC.LAM.lipid_opsonization	0.23	Nonsignificant	1.00	0.78	Other	45	14
334	FIB.barrier_purinergic.lipid_secretory	0.22	Nonsignificant	—	0.48	Other	0	0
335	EPI.renal_intercalated_cell_type_A.acid_secretion	0.22	Nonsignificant	0.97	0.38	Other	12	6
336	B.naive.purinergic	0.22	Nonsignificant	0.92	0.89	Other	384	820
337	EPI.renal_intercalated_cell_type_B.baseline	0.21	Nonsignificant	—	0.00	Other	3	1
338	B.memory.activated	0.21	Nonsignificant	1.00	0.34	Other	105	29
339	EPI.skin_keratinocyte_proliferating.anchor_remodel	0.21	Nonsignificant	—	0.18	Other	0	0
340	EC.arterial.elastic	0.21	Nonsignificant	1.00	0.37	Other	22	45
341	B.naive.metabolic	0.21	Nonsignificant	0.92	0.94	Other	50	79
342	EPI.skin_keratinocyte_proliferating.early_spinous_transition	0.20	Nonsignificant	—	0.00	Other	135	290
343	PC.IgA_muocsal.activated	0.20	Nonsignificant	0.22	1.17	Other	17	8
344	MAC.resident_iron.heme_catabolism	0.19	Nonsignificant	0.83	1.00	Other	30	51
345	FIB.barrier_secretory.homeostasis	0.19	Nonsignificant	—	0.00	Other	0	0
346	EPI.skin_appendage_keratinocyte.ductal_immune_interacting	0.19	Nonsignificant	1.00	0.88	Other	7	16
347	MONO.CD14.inflammatory	0.19	Nonsignificant	1.00	0.11	Other	92	134
348	MAC.LAM.perivascular_angiocrine	0.18	Nonsignificant	—	0.27	Other	53	138
349	EPI.lung_multiciliated.baseline	0.18	Nonsignificant	—	0.00	Other	0	7
350	EPI.salivary_serous_acinar.secretory_active	0.18	Nonsignificant	1.00	0.00	Other	242	69
351	FIB.adventitial.PI16_matrix	0.17	Nonsignificant	1.00	0.56	Other	70	90
352	B.memory.preactivated	0.17	Nonsignificant	1.00	0.27	Other	173	174
353	B.naive.restrained	0.17	Nonsignificant	0.92	0.92	Other	183	353
354	MAC.MDM.inflammatory_phagocytic	0.16	Nonsignificant	0.07	1.15	Other	199	52
355	B.naive.baseline	0.16	Nonsignificant	0.92	0.75	Other	10	13
356	FIB.skin_sheath.stress_chaperone	0.16	Nonsignificant	—	6.94e-17	Other	0	0
357	PC.IgG_systemic.secretory	0.15	Nonsignificant	1.00	0.00	Other	0	0
358	B.age_associated.activated	0.15	Nonsignificant	—	0.12	Other	18	22
359	FIB.skin_papillary.baseline	0.14	Nonsignificant	—	0.00	Other	0	0
360	EPI.endocervical_secretory.secretory_translocon	0.14	Nonsignificant	—	0.67	Other	0	0
361	FIB.perivascular_interface.lipid_shuttle	0.14	Nonsignificant	—	0.00	Other	51	170
362	MG.baseline	0.14	Nonsignificant	0.13	1.25	Other	16	5
363	EPI.intrahepatic_cholangiocyte_transport.mechanosensing_remodelling	0.14	Nonsignificant	—	0.00	Other	0	0
364	EPI.ectocervical_granular.secretory_apocrine	0.14	Nonsignificant	—	0.32	Other	0	0
365	B.age_associated.migratory	0.14	Nonsignificant	0.66	0.84	Other	2	2
366	EPI.tracheal_suprabasal.secretory_immune	0.13	Nonsignificant	—	0.00	Other	0	0
367	MESO.activated_stress	0.13	Nonsignificant	—	0.00	Other	0	0
368	PERI.angiocrine	0.13	Nonsignificant	0.75	0.98	Other	93	102
369	THYMO.DN_preTCR	0.12	Nonsignificant	1.00	1.00	Other	41	71
370	B.naive.activated	0.12	Nonsignificant	1.00	0.22	Other	77	127
371	ASPC.secretory	0.12	Nonsignificant	0.32	1.11	Other	76	5
372	B.age_associated.naive_transitional	0.12	Nonsignificant	—	0.00	Other	0	0
373	EC.venous.baseline	0.11	Nonsignificant	1.00	0.78	Other	346	807
374	EPI.ileal_enterocyte_crypt.bile_transport	0.11	Nonsignificant	0.99	0.41	Other	2	0
375	EPI.renal_thick_ascending_limb.remodeling	0.11	Nonsignificant	1.00	0.34	Other	152	92
376	PERI.inflammatory	0.10	Nonsignificant	0.75	0.99	Other	40	77
377	EPI.hepatic_ductular_cholangiocyte.ion_transport	0.10	Nonsignificant	—	0.00	Other	0	0
378	EPI.ileal_enterocyte_absorptive.villus_tip	0.10	Nonsignificant	1.00	0.00	Other	4	3
379	EPI.bile_duct_cholangiocyte.inflammatory_APC	0.10	Nonsignificant	—	0.76	Other	2	0
380	EPI.salivary_myoepithelial.contractile_repair	0.10	Nonsignificant	—	1.47	Other	3	9
381	EPI.skin_appendage_keratinocyte.ductal_barrier_detox	0.10	Nonsignificant	1.00	0.05	Other	33	34
382	EPI.skin_sweat_duct_keratinocyte.barrier	0.10	Nonsignificant	—	0.80	Other	0	0
383	FIB.adventitial.inflammatory_activated	0.10	Nonsignificant	1.00	0.47	Other	100	473
384	EPI.hepatic_ductular_cholangiocyte.lipid_mevalonate	0.10	Nonsignificant	—	0.00	Other	0	0
385	FIB.skin_tenogenic.baseline	0.10	Nonsignificant	—	0.00	Other	0	2
386	FIB.skin_sheath.ECM_immune	0.10	Nonsignificant	—	0.00	Other	0	0
387	EPI.intrahepatic_cholangiocyte_defense.raft_maturation	0.09	Nonsignificant	—	0.00	Other	0	0
388	B.germinal_center.DZ_S_phase	0.09	Nonsignificant	—	0.00	Other	0	0
389	PC.IgA_muocsal.baseline	0.09	Nonsignificant	0.99	0.58	Other	3	5
390	FIB.barrier_purinergic.stress_GF_binding	0.08	Nonsignificant	—	0.00	Other	0	0
391	FIB.adventitial.adhesion_lipid	0.08	Nonsignificant	1.00	0.81	Other	58	209
392	ASPC.activated	0.08	Nonsignificant	1.00	0.95	Other	164	162
393	ASPC.preadipocyte_lipid_primed	0.08	Nonsignificant	1.00	0.99	Other	331	129
394	EPI.skin_hair_follicle_companion.activated_migratory	0.08	Nonsignificant	—	0.00	Other	0	0
395	MAC.resident_iron.APC_iron_sensing	0.08	Nonsignificant	0.96	0.63	Other	211	114
396	EPI.renal_immature_ureteric_bud.defense_secretory	0.08	Nonsignificant	0.15	1.32	Other	45	76
397	GRANU.MAST.resting_granule	0.07	Nonsignificant	—	0.63	Other	0	0
398	FIB.interstitial.remodeling	0.07	Nonsignificant	0.17	1.15	Other	31	9
399	MAC.resident_iron.stress_tolerogenic	0.07	Nonsignificant	—	0.00	Other	0	0
400	NK.immature_bridge	0.07	Nonsignificant	0.69	1.05	Other	117	122
401	MESO.secretory_structural	0.07	Nonsignificant	—	0.38	Other	0	0
402	T.CD4_Th2.precursor	0.06	Nonsignificant	—	0.00	Other	0	0
403	EPI.renal_immature_ureteric_bud.osmoprotective	0.06	Nonsignificant	0.55	1.00	Other	126	44
404	EPI.ileal_enterocyte_crypt.villus_transition	0.06	Nonsignificant	—	0.00	Other	7	10
405	EPI.renal_thick_ascending_limb.barrier_repair	0.06	Nonsignificant	1.00	0.39	Other	141	284
406	MAC.LAM.lipid_phagocytosis	0.06	Nonsignificant	1.00	0.46	Other	369	328
407	DC.cDC2.antiviral	0.05	Nonsignificant	0.99	0.78	Other	100	37
408	FIB.tracheal_subepithelial.baseline	0.05	Nonsignificant	—	0.00	Other	0	0
409	MG.expanding	0.04	Nonsignificant	1.00	0.84	Other	2	1
410	MAC.resident_repair.lipid_phagocytic	0.04	Nonsignificant	0.69	1.20	Other	228	604
411	MAC.MDM.complement_resolving	0.04	Nonsignificant	0.83	1.00	Other	440	860
412	GRANU.MAST.activated_repair	0.04	Nonsignificant	—	0.00	Other	0	1
413	THYMO.SP_CD8_naive_stress	0.04	Nonsignificant	1.00	0.95	Other	1	1
414	FIB.interstitial.immune_interact	0.04	Nonsignificant	0.42	1.07	Other	12	1
415	ASPC.baseline	0.04	Nonsignificant	1.00	0.93	Other	363	170
416	EPI.skin_follicular_keratinizing.root_infundibulum	0.04	Nonsignificant	—	0.86	Other	0	0
417	FIB.interstitial.mesenchymal_regulator	0.04	Nonsignificant	0.34	1.14	Other	4	4
418	MESO.antiviral	0.04	Nonsignificant	—	0.00	Other	3	8
419	NEU.INH_VIP.develop_niche	0.04	Nonsignificant	—	0.00	Other	0	0
420	GRANU.MAST.activated_acute	0.04	Nonsignificant	—	0.00	Other	0	0
421	ASPC.adipocyte_capillary_interface	0.03	Nonsignificant	1.00	0.82	Other	21	54
422	B.germinal_center.DZ_M_phase	0.03	Nonsignificant	—	0.00	Other	0	0
423	EPI.salivary_myoepithelial.junctional_transport	0.03	Nonsignificant	0.49	1.37	Other	66	121
424	OLG.stress	0.03	Nonsignificant	0.17	1.16	Other	232	8
425	MESO.baseline	0.03	Nonsignificant	0.92	0.58	Other	0	6
426	EPI.salivary_myoepithelial.baseline	0.02	Nonsignificant	0.78	1.02	Other	42	141
427	EPI.skin_hair_follicle_bulge.anagen_growth	0.02	Nonsignificant	—	0.67	Other	0	0
428	DC.cDC2.tolerogenic_regulatory	0.02	Nonsignificant	0.99	0.81	Other	44	4
429	ASPC.niche_keeping_progenitor	0.02	Nonsignificant	1.00	0.65	Other	52	219
430	ASPC.inflammatory	0.02	Nonsignificant	1.00	0.81	Other	21	61
431	FIB.transitioning.secretory_procollagen	0.02	Nonsignificant	—	0.85	Other	0	0
432	FIB.reticular.immune_interface	0.02	Nonsignificant	—	0.16	Other	1	6
433	DC.cDC1.cross_presenting	0.02	Nonsignificant	—	1.21	Other	0	0
434	EC.venous.activated	0.02	Nonsignificant	1.00	0.38	Other	247	752
435	FIB.lung_alveolar.stress_interacting	0.02	Nonsignificant	—	0.97	Other	0	0
436	FIB.adventitial.activated_remodelling	0.02	Nonsignificant	—	0.00	Other	141	319
437	THYMO.SP_CD8_transitional	0.02	Nonsignificant	1.00	0.94	Other	32	75
438	MAC.MDM.LAM_like	0.02	Nonsignificant	0.83	1.00	Other	12	14
439	MAC.resident_repair.chemokine_angiocrine	0.02	Nonsignificant	0.60	1.11	Other	87	138
440	OLG.myelinating_mature	0.02	Nonsignificant	0.43	1.07	Other	363	94
441	FIB.reticular.stromal_niche	0.02	Nonsignificant	0.19	1.24	Other	0	0
442	CHOND.activated_fibro_like	0.02	Nonsignificant	0.33	1.10	Other	531	188
443	EPI.skin_follicular_keratinizing.transit_amplifying	0.02	Nonsignificant	—	0.00	Other	21	49
444	EC.venous.adipose_lipid	0.02	Nonsignificant	1.00	0.29	Other	254	476
445	MAC.resident_cardiac.antigen_presenting	0.02	Nonsignificant	0.55	1.12	Other	52	27
446	OLG.myelinating_stress	0.02	Nonsignificant	0.88	1.01	Other	232	62
447	T.CD4_transitional.APC_interacting	0.02	Nonsignificant	0.23	1.25	Other	10	14
448	MAC.resident_cardiac.inflammatory_reparative	0.02	Nonsignificant	0.55	1.10	Other	31	96
449	EPI.skin_follicular_keratinizing.upper_infundibulum	0.02	Nonsignificant	—	0.00	Other	8	2
450	EPI.skin_keratinocyte_progenitor.activated_stress	0.01	Nonsignificant	—	0.38	Other	0	0
451	T.CD8_Trm.dendritic_recruiter	0.01	Nonsignificant	0.82	1.11	Other	47	85
452	MAC.LAM.anti_inflammatory	0.01	Nonsignificant	1.00	0.18	Other	86	132
453	MAC.MDM.APC_dendritic	0.01	Nonsignificant	0.83	0.91	Other	48	15
454	EPI.salivary_duct_ion_transport.baseline	0.01	Nonsignificant	—	—	Other	0	0
455	EPI.salivary_myoepithelial.activated	0.01	Nonsignificant	0.99	0.14	Other	85	281
456	FIB.transitioning.ISG_primed_interface	0.01	Nonsignificant	—	0.25	Other	17	80
457	EPI.salivary_intercalated_defense.canonical_antimicrobial	0.01	Nonsignificant	0.07	1.29	Other	11	22
458	MAC.microglia_like.inflammatory_chemokine	0.01	Nonsignificant	—	0.44	Other	20	32
459	OLG.regulatory_activated	0.01	Nonsignificant	0.43	1.12	Other	196	614
460	ASPC.remodeling	0.01	Nonsignificant	1.00	0.94	Other	106	354
461	T.CD4_transitional.tissue_enagement	0.01	Nonsignificant	0.55	1.16	Other	5	11
462	T.CD4_Treg.tissue_effector	9.93e-03	Nonsignificant	0.40	1.10	Other	16	13
463	MAC.resident_cardiac.phagocytic_homeostasis	9.89e-03	Nonsignificant	0.94	0.73	Other	564	1,221
464	MUSC.baseline	9.79e-03	Nonsignificant	0.30	1.44	Other	0	0
465	THYMO.DP_early_stress	9.35e-03	Nonsignificant	—	0.62	Other	0	0
466	FIB.barrier_secretory.remodeling	9.30e-03	Nonsignificant	—	0.00	Other	0	0
467	OLG.regulatory	9.28e-03	Nonsignificant	0.98	0.83	Other	353	73
468	CHOND.remodeling	9.27e-03	Nonsignificant	—	0.78	Other	5	0
469	DC.cDC1.baseline	9.23e-03	Nonsignificant	—	0.16	Other	0	0
470	EPI.skin_hair_follicle_bulge.quiescent	8.81e-03	Nonsignificant	1.00	0.00	Other	56	69
471	T.CD4_Treg.APC_interactive	8.59e-03	Nonsignificant	0.11	1.21	Other	118	28
472	CHOND.articular_collagen	8.46e-03	Nonsignificant	1.00	0.91	Other	551	266
473	T.CD4_Trm.baseline	8.06e-03	Nonsignificant	0.73	1.13	Other	31	21
474	DC.cDC1.activated	8.06e-03	Nonsignificant	—	0.00	Other	0	0
475	OLG.reactive_repair	7.44e-03	Nonsignificant	0.97	0.94	Other	385	385
476	FIB.hepatic_stellate_cell.fibrogenic	7.41e-03	Nonsignificant	—	0.73	Other	0	0
477	OLG.vesicle_trafficking	7.34e-03	Nonsignificant	0.98	0.80	Other	124	10
478	CM.baseline	7.14e-03	Nonsignificant	1.00	0.97	Other	393	0
479	SCHWN.axon_contact_cardiac	7.05e-03	Nonsignificant	0.77	0.75	Other	18	63
480	DC.cDC1.proliferative	6.89e-03	Nonsignificant	—	0.00	Other	0	0
481	MG.phagocytic_APC	6.73e-03	Nonsignificant	1.00	0.10	Other	25	8
482	FIB.lung_alveolar.mito_secretory	6.62e-03	Nonsignificant	—	0.00	Other	0	0
483	T.CD8_transitional.Trm_primed	6.36e-03	Nonsignificant	0.60	1.03	Other	108	15
484	EPI.ileal_bile_transport.detox_transcytosis	6.30e-03	Nonsignificant	—	0.45	Other	0	1
485	SCHWN.translation_boost	6.23e-03	Nonsignificant	—	0.03	Other	8	1
486	T.CD4_transitional.baseline	6.04e-03	Nonsignificant	0.23	1.09	Other	59	97
487	T.CD4_Tem.inflammatory	5.91e-03	Nonsignificant	0.60	1.02	Other	28	6
488	FIB.interstitial.lipid_matrix	5.85e-03	Nonsignificant	0.99	0.78	Other	258	191
489	THYMO.DP_early	5.84e-03	Nonsignificant	1.00	0.97	Other	326	313
490	MUSC.quiescent_reservoir	5.78e-03	Nonsignificant	0.84	1.10	Other	2	8
491	EPI.skin_keratinocyte_basal.transit_amplifying	5.55e-03	Nonsignificant	—	0.97	Other	0	0
492	ASPC.stem_like_progenitor	5.36e-03	Nonsignificant	1.00	0.64	Other	300	842
493	NK.cytokine_quiescent	5.30e-03	Nonsignificant	0.69	1.05	Other	623	1,062
494	EPI.ileal_bile_transport.absorptive_xenobiotic	5.29e-03	Nonsignificant	0.77	0.69	Other	11	12
495	T.CD4_Th17.cytotoxic	5.12e-03	Nonsignificant	5.07e-04	1.18	Other	332	123
496	SCHWN.reactive_inflammatory	5.09e-03	Nonsignificant	—	0.00	Other	0	0
497	FIB.transitioning.motility_remodelling	5.07e-03	Nonsignificant	—	0.00	Other	0	0
498	FIB.reticular.stress_metallothionein	4.94e-03	Nonsignificant	—	0.00	Other	3	32
499	EPI.ectocervical_granular.immune_interact	4.93e-03	Nonsignificant	—	0.00	Other	0	0
500	T.CD4_transitional.primed_cytotoxic	4.57e-03	Nonsignificant	0.73	0.98	Other	28	30
501	T.CD8_transitional.early	4.39e-03	Nonsignificant	0.60	1.03	Other	327	55
502	PERI.cardiac_skeletal	4.26e-03	Nonsignificant	1.00	0.02	Other	313	630
503	FIB.interstitial.mesenchymal_APC	4.16e-03	Nonsignificant	0.99	0.76	Other	81	33
504	T.CD8_Trm.homeostatic	4.16e-03	Nonsignificant	0.82	1.03	Other	42	5
505	EPI.bile_duct_cholangiocyte.secretory_mucin	4.04e-03	Nonsignificant	—	0.00	Other	7	12
506	FIB.hepatic_stellate_cell.inflammatory	3.84e-03	Nonsignificant	—	0.00	Other	0	0
507	MAC.resident_repair.antigen_presenting	3.60e-03	Nonsignificant	0.97	0.99	Other	244	113
508	EPI.skin_keratinocyte_basal.basement_anchoring	3.47e-03	Nonsignificant	—	0.00	Other	0	0
509	T.CD4_transitional.primed_helper_effector	3.42e-03	Nonsignificant	0.73	0.95	Other	19	43
510	T.CD4_Tem.long_term_memory	3.41e-03	Nonsignificant	0.60	1.05	Other	314	587
511	MUSC.early_activation	3.12e-03	Nonsignificant	0.84	0.54	Other	4	32
512	MUSC.activated_migratory	3.09e-03	Nonsignificant	0.84	0.60	Other	6	7
513	FIB.hepatic_stellate_cell.contractile	3.02e-03	Nonsignificant	—	0.00	Other	0	0
514	NK.cytokine_biosynthetic_primed	3.01e-03	Nonsignificant	0.91	1.07	Other	360	21
515	T.CD8_transitional.effector_primed	2.98e-03	Nonsignificant	0.60	1.00	Other	435	151
516	EPI.ectocervical_granular.proliferative_basal	2.84e-03	Nonsignificant	—	0.00	Other	0	0
517	ILC2.activated	2.79e-03	Nonsignificant	—	0.00	Other	0	0
518	DC.cDC2.pro_inflammatory	2.75e-03	Nonsignificant	0.99	0.52	Other	3	5
519	T.CD4_Tcm.RNA_control	2.73e-03	Nonsignificant	0.05	1.11	Other	96	4
520	T.CD4_Tcm.tissue_homing	2.67e-03	Nonsignificant	0.74	1.06	Other	78	46
521	MAC.resident_iron.heme_recycling	2.66e-03	Nonsignificant	—	0.00	Other	30	37
522	FIB.transitioning.matrix_stress	2.56e-03	Nonsignificant	—	0.00	Other	47	138
523	DC.cDC2.lipid_metabolic	2.26e-03	Nonsignificant	—	0.00	Other	0	0
524	NK.cytokine_axis_baseline	2.12e-03	Nonsignificant	1.00	0.99	Other	1,172	116
525	T.CD8_transitional.APC_like	2.07e-03	Nonsignificant	0.60	1.00	Other	205	62
526	EPI.salivary_duct_excretory.baseline	1.97e-03	Nonsignificant	0.41	1.17	Other	23	57
527	MAC.microglia_like.patrolling_adhesive	1.79e-03	Nonsignificant	—	0.32	Other	0	0
528	T.CD4_Tfh.canonical_GC_helper	1.77e-03	Nonsignificant	0.33	1.12	Other	1	2
529	ILC2.migratory	1.74e-03	Nonsignificant	—	6.94e-17	Other	0	0
530	T.CD4_Trm.central_like	1.73e-03	Nonsignificant	0.73	1.15	Other	38	31
531	T.CD8_Trm.inflammatory	1.73e-03	Nonsignificant	0.98	0.92	Other	124	176
532	T.CD8_naive.nfkb_related	1.72e-03	Nonsignificant	0.77	1.14	Other	1	0
533	T.MAIT.migratory	1.72e-03	Nonsignificant	0.64	1.19	Other	10	1
534	EPI.renal_proximal_tubule.onecarbon_peroxisome	1.68e-03	Nonsignificant	0.17	1.62	Other	58	89
535	EPI.salivary_intercalated_defense.inflammatory	1.56e-03	Nonsignificant	0.95	0.65	Other	152	360
536	EPI.skin_sebaceous_duct_luminal.ECM_remodelling	1.47e-03	Nonsignificant	0.02	1.40	Other	2	9
537	T.CD4_Tcm.Th2_like	1.38e-03	Nonsignificant	0.74	1.04	Other	23	55
538	T.CD4_Tcm.Tfh_like	1.37e-03	Nonsignificant	0.67	1.07	Other	102	214
539	DC.cDC1.homeostatic_inhibitory	1.37e-03	Nonsignificant	—	0.00	Other	0	0
540	T.CD4_Tcm.regulatory_poised	1.33e-03	Nonsignificant	0.74	1.05	Other	2	3
541	T.CD4_naive.Treg_like	1.25e-03	Nonsignificant	0.48	1.19	Other	121	72
542	T.CD4_Tfh.suppression_exhaustion	1.24e-03	Nonsignificant	0.59	1.04	Other	0	2
543	EPI.salivary_duct_excretory.stress	1.20e-03	Nonsignificant	0.41	1.17	Other	33	68
544	T.CD8_Tem.signaling_turnover	1.19e-03	Nonsignificant	0.91	1.09	Other	425	683
545	EPI.skin_interfollicular_spinous.upper_lipid	1.17e-03	Nonsignificant	—	1.45	Other	6	6
546	T.CD8_Tem.baseline	1.17e-03	Nonsignificant	0.56	1.04	Other	458	356
547	EPI.renal_proximal_tubule.detox_antioxidant	1.16e-03	Nonsignificant	0.96	0.24	Other	394	77
548	T.CD8_naive.vesicle_secretory	1.05e-03	Nonsignificant	0.12	1.12	Other	42	0
549	T.CD8_Trm.muscosal_Tc17	1.02e-03	Nonsignificant	0.98	0.92	Other	19	38
550	T.CD8_Tem.TEMRA	1.02e-03	Nonsignificant	0.91	1.01	Other	920	1,088
551	FIB.interstitial.stress_secretory	9.70e-04	Nonsignificant	0.99	0.49	Other	92	56
552	T.CD4_Tcm.effector_like	9.60e-04	Nonsignificant	0.74	1.01	Other	293	533
553	T.CD4_Tem.cytotoxic_effector	9.58e-04	Nonsignificant	0.60	1.04	Other	225	398
554	T.CD4_naive.mature	9.57e-04	Nonsignificant	0.48	1.03	Other	211	100
555	MAC.resident_repair.ECM_stromal_crosstalk	9.40e-04	Nonsignificant	0.97	0.71	Other	95	158
556	T.MAIT.early_activation	9.36e-04	Nonsignificant	0.27	1.21	Other	57	4
557	T.CD4_Tcm.imprinted_splicing	9.18e-04	Nonsignificant	0.74	1.05	Other	6	17
558	EPI.skin_sweat_duct_keratinocyte.proliferative_S	9.17e-04	Nonsignificant	—	0.09	Other	0	0
559	T.CD4_Treg.Tr1_like	8.99e-04	Nonsignificant	—	0.00	Other	8	8
560	EPI.salivary_intercalated_defense.basal_EMT	8.76e-04	Nonsignificant	—	0.00	Other	0	0
561	FIB.reticular.ECM_builder	8.37e-04	Nonsignificant	—	0.00	Other	0	0
562	NK.cytokine_lung_immediate_early	8.35e-04	Nonsignificant	1.00	1.02	Other	424	274
563	EPI.thymic_medullary.proliferative_APC	8.19e-04	Nonsignificant	—	1.17	Other	0	0
564	T.MAIT.MAPK_brake	8.17e-04	Nonsignificant	0.82	1.13	Other	44	66
565	DC.mig.baseline	8.17e-04	Nonsignificant	—	0.00	Other	1	0
566	MAC.resident_repair.stress_iron	8.05e-04	Nonsignificant	0.97	0.74	Other	48	97
567	EPI.cervical_suprabasal.inflammatory_repair	8.01e-04	Nonsignificant	—	0.00	Other	0	0
568	T.CD4_Trm.activated	7.84e-04	Nonsignificant	0.76	1.11	Other	32	26
569	EPI.endocervical_secretory.squamous_barrier	7.79e-04	Nonsignificant	—	0.00	Other	0	0
570	T.CD8_transitional.stress	7.41e-04	Nonsignificant	—	0.74	Other	24	34
571	CM.osmoprotection	6.78e-04	Nonsignificant	1.00	1.03	Other	34	57
572	EPI.skin_sebaceous_duct_luminal.immune_interface	6.56e-04	Nonsignificant	—	0.46	Other	0	0
573	T.CD4_Tcm.stress	6.27e-04	Nonsignificant	0.74	1.04	Other	5	11
574	T.CD8_Tcm.helper_like	6.12e-04	Nonsignificant	0.39	1.07	Other	81	159
575	EPI.skin_sweat_duct_keratinocyte.repair	5.63e-04	Nonsignificant	—	0.00	Other	0	0
576	T.CD8_Trm.cytotoxic	5.40e-04	Nonsignificant	0.98	0.85	Other	165	85
577	NK.adaptive_axis_baseline	5.32e-04	Nonsignificant	1.00	1.02	Other	1,008	153
578	T.CD8_Tcm.NK_like	5.26e-04	Nonsignificant	0.59	1.11	Other	334	581
579	T.CD4_Tcm.crosstalk_myeloid	5.25e-04	Nonsignificant	0.74	1.01	Other	5	4
580	T.CD4_naive.neddylation_mitoprot	5.05e-04	Nonsignificant	0.87	1.01	Other	93	56
581	CM.mechano_activated	5.00e-04	Nonsignificant	1.00	1.04	Other	205	134
582	T.CD4_Th17.migratory	4.98e-04	Nonsignificant	0.91	0.94	Other	13	23
583	T.CD4_naive.homeostatic	4.61e-04	Nonsignificant	0.87	1.02	Other	215	108
584	NK.cytokine_tissue_resident	4.58e-04	Nonsignificant	1.00	1.09	Other	74	82
585	EPI.skin_sweat_duct_keratinocyte.suprabasal_hypoxic	4.52e-04	Nonsignificant	—	0.00	Other	0	0
586	CHOND.angiogenic	4.51e-04	Nonsignificant	—	0.25	Other	0	0
587	T.gamma_delta.early_effector	4.33e-04	Nonsignificant	0.51	1.06	Other	89	0
588	T.CD4_Tfh.effector_migratory	4.21e-04	Nonsignificant	0.78	0.93	Other	122	57
589	T.CD8_naive.effector_transition	4.20e-04	Nonsignificant	0.80	1.04	Other	35	62
590	THYMO.SP_CD4_naive	4.00e-04	Nonsignificant	1.00	0.75	Other	65	75
591	CM.sarcomere_actin_interface	3.99e-04	Nonsignificant	1.00	0.95	Other	450	78
592	EPI.thymic_cortical.secretory_remodeling	3.92e-04	Nonsignificant	—	0.00	Other	4	1
593	T.CD4_Th17.baseline	3.89e-04	Nonsignificant	0.91	0.86	Other	51	5
594	T.CD4_Tcm.DC_interact	3.50e-04	Nonsignificant	0.74	1.02	Other	72	32
595	NK.adaptive_immature_precursor	3.33e-04	Nonsignificant	1.00	0.99	Other	358	111
596	T.CD4_Tfh.precursor_migratory	3.26e-04	Nonsignificant	0.16	1.17	Other	72	27
597	T.CD4_Tcm.migratory_cilium	3.11e-04	Nonsignificant	0.74	1.05	Other	5	10
598	T.gamma_delta.central_memory	3.06e-04	Nonsignificant	0.51	1.07	Other	460	919
599	T.CD4_naive.neddylation	3.05e-04	Nonsignificant	0.48	1.04	Other	104	222
600	T.CD4_Trm.cytotoxic_effector	2.97e-04	Nonsignificant	0.87	0.95	Other	118	77
601	T.CD4_naive.survival	2.62e-04	Nonsignificant	0.87	1.03	Other	12	17
602	CM.translation_boost_RPL	2.53e-04	Nonsignificant	1.00	0.95	Other	129	1
603	EPI.thymic_medullary.canonical_alarmin	2.49e-04	Nonsignificant	0.34	1.25	Other	8	17
604	CHOND.pro_inflammatory	2.36e-04	Nonsignificant	1.00	0.58	Other	181	351
605	CM.oxidative_phospho	2.33e-04	Nonsignificant	1.00	0.97	Other	266	792
606	T.CD8_naive.baseline	2.26e-04	Nonsignificant	0.80	0.99	Other	142	2
607	T.CD4_Tcm.baseline	2.23e-04	Nonsignificant	0.74	1.00	Other	61	31
608	T.CD8_Tcm.effector_bias	2.22e-04	Nonsignificant	0.25	1.13	Other	199	329
609	T.CD4_Tcm.secretory	2.21e-04	Nonsignificant	0.74	1.07	Other	20	11
610	EPI.skin_keratinocyte_basal.spinous_transition	2.00e-04	Nonsignificant	—	0.00	Other	0	0
611	T.CD8_Tem.early_helper_like	1.83e-04	Nonsignificant	0.91	1.02	Other	445	755
612	NK.cytokine_repair_primed	1.73e-04	Nonsignificant	1.00	1.04	Other	266	11
613	EPI.skin_keratinocyte_progenitor.quiescent_stem_like	1.73e-04	Nonsignificant	—	0.00	Other	0	0
614	EPI.skin_sebaceous_duct_luminal.secretoglobin_neuro	1.71e-04	Nonsignificant	—	0.00	Other	0	0
615	T.CD8_naive.cytokine_dampened	1.63e-04	Nonsignificant	0.80	0.99	Other	71	4
616	T.CD8_naive.splicing_enriched	1.49e-04	Nonsignificant	0.80	0.99	Other	120	16
617	T.CD4_Trm.helper_like	1.34e-04	Nonsignificant	0.91	0.85	Other	84	147
618	T.gamma_delta.cytotoxic_effector	1.24e-04	Nonsignificant	0.51	1.04	Other	349	109
619	T.CD4_cytotoxic.terminal_effector	1.24e-04	Nonsignificant	0.46	1.09	Other	286	21
620	NK.cytokine_tissue_activation	1.22e-04	Nonsignificant	1.00	1.00	Other	267	450
621	T.CD4_Trm.metal_stress	1.04e-04	Nonsignificant	0.91	0.73	Other	34	58
622	T.CD4_Tem.transitional_CM	9.74e-05	Nonsignificant	0.92	0.85	Other	31	20
623	T.CD8_naive.mito_proteostasis	9.42e-05	Nonsignificant	0.80	1.04	Other	428	100
624	EPI.skin_sweat_duct_keratinocyte.signal_gate	9.36e-05	Nonsignificant	—	0.00	Other	43	26
625	T.CD4_cytotoxic.baseline	8.77e-05	Nonsignificant	0.46	1.26	Other	0	0
626	NK.cytokine_vascular_patrolling	8.59e-05	Nonsignificant	1.00	0.91	Other	863	94
627	EPI.cervical_suprabasal.secretory_vesicle	8.29e-05	Nonsignificant	—	0.00	Other	0	0
628	THYMO.SP_CD8_naive	8.25e-05	Nonsignificant	1.00	0.38	Other	297	177
629	EPI.skin_interfollicular_spinous.inflammatory	8.09e-05	Nonsignificant	—	0.00	Other	0	0
630	T.CD4_naive.mature_mitoprot	7.93e-05	Nonsignificant	0.91	0.97	Other	212	476
631	MAC.microglia_like.phagocytic_redox	7.50e-05	Nonsignificant	—	0.00	Other	0	0
632	EPI.thymic_cortical.baseline	7.07e-05	Nonsignificant	0.62	0.82	Other	185	386
633	EPI.alveolar_type_2.baseline_surfactant	6.66e-05	Nonsignificant	0.43	1.10	Other	64	9
634	T.CD4_Tcm.synapse_dynamics	6.58e-05	Nonsignificant	0.86	0.95	Other	15	10
635	EPI.thymic_cortical.Notch_interface	6.52e-05	Nonsignificant	—	0.00	Other	82	137
636	T.CD4_naive.resist_bystander	6.37e-05	Nonsignificant	0.87	0.98	Other	40	25
637	NK.adaptive_classII_inhibitory	6.02e-05	Nonsignificant	1.00	0.93	Other	880	154
638	CM.inflammatory	5.91e-05	Nonsignificant	—	0.93	Other	0	0
639	T.CD4_Trm.stress_adaptive	5.65e-05	Nonsignificant	0.87	0.97	Other	8	22
640	T.CD4_cytotoxic.activated	5.59e-05	Nonsignificant	0.46	1.18	Other	3	1
641	EPI.skin_sweat_duct_keratinocyte.cornifying_acrosyringeal	5.40e-05	Nonsignificant	—	0.00	Other	0	0
642	THYMO.CD8aa_IELp	4.69e-05	Nonsignificant	—	0.00	Other	1	7
643	CM.mito_proteostasis	4.47e-05	Nonsignificant	1.00	0.94	Other	329	29
644	EPI.skin_sebaceous_duct_luminal.detox_repair	3.88e-05	Nonsignificant	0.98	0.48	Other	137	94
645	T.CD4_Tcm.APC_mimicry	3.66e-05	Nonsignificant	0.89	0.87	Other	54	43
646	T.MAIT.vesicle	3.66e-05	Nonsignificant	0.94	0.71	Other	37	65
647	T.CD4_naive.survival_mitoprot	3.59e-05	Nonsignificant	0.87	1.01	Other	13	7
648	NK.adaptive_HLAE_tuned	3.58e-05	Nonsignificant	1.00	0.91	Other	1,124	189
649	EPI.lung_club_secretory.inflammatory	3.54e-05	Nonsignificant	—	0.00	Other	0	0
650	T.CD4_naive.survival_neddylation	3.14e-05	Nonsignificant	0.87	0.98	Other	26	38
651	T.CD8_Tem.stress_adapted	2.78e-05	Nonsignificant	0.95	0.90	Other	607	520
652	T.MAIT.quiescent	2.41e-05	Nonsignificant	0.94	0.61	Other	100	5
653	SKM.type_1_slow.contractile	2.33e-05	Nonsignificant	0.01	1.13	Other	596	8
654	T.CD4_naive.proteostasis	2.28e-05	Nonsignificant	0.87	0.97	Other	14	9
655	T.CD4_naive.proteostasis_mitoprot	1.91e-05	Nonsignificant	0.87	0.98	Other	15	37
656	EPI.thymic_medullary.hormone_xeno_barrier	1.87e-05	Nonsignificant	—	0.00	Other	0	8
657	EPI.skin_interfollicular_spinous.stress_oxidative	1.83e-05	Nonsignificant	—	0.00	Other	0	0
658	T.MAIT.cytotoxic	1.71e-05	Nonsignificant	0.94	0.59	Other	52	15
659	T.CD4_Treg.central_naive_like	1.64e-05	Nonsignificant	1.00	0.03	Other	333	45
660	CM.translation_boost_RPS	1.60e-05	Nonsignificant	1.00	0.87	Other	69	16
661	T.MAIT.stress	1.42e-05	Nonsignificant	—	0.00	Other	0	0
662	EPI.thymic_medullary.stress_APC	1.28e-05	Nonsignificant	0.98	0.12	Other	2	4
663	SKM.type_2_fast.oxidative_IIa	1.08e-05	Nonsignificant	0.03	1.06	Other	946	56
664	T.CD4_Tcm.retro_ZNF117	1.04e-05	Nonsignificant	0.89	0.86	Other	5	9
665	EPI.skin_interfollicular_spinous.transition_basal	1.04e-05	Nonsignificant	0.92	0.92	Other	100	127
666	EPI.alveolar_type_2.injury_primed	1.00e-05	Nonsignificant	0.43	1.07	Other	434	245
667	T.CD8_naive.lipid_synthesis	8.70e-06	Nonsignificant	0.80	0.99	Other	6	4
668	T.CD4_naive.activated_stress	8.50e-06	Nonsignificant	0.87	0.99	Other	339	429
669	NK.adaptive_terminal_cytotoxic	6.53e-06	Nonsignificant	1.00	0.74	Other	485	802
670	EPI.skin_interfollicular_spinous.baseline	6.19e-06	Nonsignificant	0.92	0.79	Other	35	3
671	SKM.type_1_slow.glycolytic	5.34e-06	Nonsignificant	0.72	1.03	Other	362	647
672	T.CD8_Tem.motility_primed	4.11e-06	Nonsignificant	0.91	0.92	Other	269	4
673	T.CD4_cytotoxic.precursor	3.13e-06	Nonsignificant	0.94	0.85	Other	156	67
674	EPI.skin_interfollicular_spinous.early_differentiation	2.99e-06	Nonsignificant	0.92	0.71	Other	89	19
675	T.CD8_Tcm.gut_homing	2.27e-06	Nonsignificant	1.00	0.68	Other	380	112
676	CM.anti_inflammatory	2.16e-06	Nonsignificant	1.00	0.78	Other	424	1,503
677	T.CD8_Tcm.baseline	1.70e-06	Nonsignificant	1.00	0.46	Other	90	89
678	NK.adaptive_biosynthetic_primed	1.60e-06	Nonsignificant	1.00	0.66	Other	244	405
679	T.CD4_naive.gut_prone	1.36e-06	Nonsignificant	0.87	0.93	Other	35	70
680	EPI.skin_interfollicular_spinous.stress_UPR	1.25e-06	Nonsignificant	—	0.00	Other	0	0
681	EPI.skin_interfollicular_spinous.proliferative	1.21e-06	Nonsignificant	—	0.00	Other	0	0
682	SKM.type_2_fast.glycolytic_IIx_IIb	1.05e-06	Nonsignificant	0.41	1.02	Other	565	1,482
683	NK.adaptive_adipose_stress	1.05e-06	Nonsignificant	1.00	0.47	Other	374	39
684	T.CD4_naive.purinergic	1.04e-06	Nonsignificant	0.91	0.88	Other	49	1
685	T.CD8_naive.innate_like	1.01e-06	Nonsignificant	0.93	0.66	Other	10	1
686	EPI.alveolar_type_2.stress_response	3.57e-07	Nonsignificant	1.00	0.71	Other	675	1,562
687	SKM.type_1_slow.oxidative	3.42e-07	Nonsignificant	1.00	0.67	Other	802	251
688	T.CD4_cytotoxic.NK_adapted	1.91e-07	Nonsignificant	0.97	0.54	Other	82	33

Associated genes: best evidence per gene

One row per gene, using its best association: priority ascending (01 before 02), then gene credibility score descending. G-tier and C-tier are the source genetic and cellular tiers from that same winning association. Score is the gene_credibility_score, not an IC score, expression measurement or new P-value. The marker column lists exact matches to the supplied annotation marker lists, with hierarchy levels. The separate scope-pooled enriched column lists exact matches to the union of up to 100 Enriched-tier genes per population from every valid published scope. Genes first require expression > 0.01 in at least 5% of finite-valued cells and log2 fold change > 2, then are ranked by descending log2 fold change using full-population cells. Fewer than 100 qualifying genes are retained without lower-tier backfill. Each population appears only once per gene; larger match lists use a compact link to their complete named-cell list. This is a candidate pool, not enrichment in every scope. Both columns match gene symbols case-insensitively, without aliases or inheritance. Enriched genes are not automatically annotation markers or specific to one cell type. A blank match in either column does not prove absence of expression. Use only matches belonging to the requested scope and level from both columns. Read the linked cell-gene reference for the supporting scope, rank, enrichment detection percentage and comparison-cell counts. Prioritize the requested scope and level; Overview is broader context, and enrichment found only in another scope is not local evidence. IC means remain full-atlas values. Marker and enrichment overlap are distinct supporting context, not proof of causality or treatment efficacy. The linked cell-gene reference provides every marker and scope-specific top-100 score.

Complete annotation marker lists · Complete markers and scope-aware enriched-gene evidence for all cell types, subtypes and states

892 unique genes. Showing 1–892. The complete list is available through the ordinary gene-table page links; no genes are omitted.

Best gene associations, ordered by priority then score
Gene	Priority	Score	MAGMA −log10(P)	G-tier	C-tier	Marker of cell types/states	Enriched in trait related cells	Scope-pooled enriched in cell types/states	Meta traits (High Priority)	Individual traits (High Priority)
THADA	01-High	0.69	23.63	G1	C1	—	MONO.CD14.remodeling (Tier: specific)	14 cells — complete matches	58	135
WFS1	01-High	0.62	16.79	G1	C1	EC.lymphatic.baseline (L2)	—	19 cells — complete matches	3	20
CCND2-AS1	01-High	0.60	15.22	G1	C1	—	—	23 cells — complete matches	25	102
ENSG00000277945	01-High	0.60	10.83	G1	C1	—	—	—	13	44
CRB2	01-High	0.60	8.76	G1	C1	—	induced_pluripotent_stem_cell (Tier: relevant) IPSC.induced_pluripotent_stem_cell (Tier: relevant) IPSC.midbrain_primed (Tier: relevant)	9 cells — complete matches	8	15
ENSG00000290063	01-High	0.59	14.61	G1	C1	—	—	—	25	102
ENSG00000307974	01-High	0.59	21.40	G1	C1	—	—	—	39	140
ENSG00000308008	01-High	0.59	21.40	G1	C1	—	—	—	39	140
ZFP36L2	01-High	0.59	21.40	G1	C1	EPI.esophageal_suprabasal.basal_transitional (L2), EPI.skin_keratinocyte_progenitor.quiescent_stem_like (L2), EPI.skin_keratinocyte_proliferating.anchor_remodel (L2)	—	79 cells — complete matches	39	140
CCND2	01-High	0.59	12.07	G1	C1	—	—	36 cells — complete matches	11	45
BCAR1	01-High	0.58	3.10	G1	C1	—	—	14 cells — complete matches	53	82
ENSG00000285901	01-High	0.58	11.72	G1	C1	—	—	—	8	30
ENSG00000286176	01-High	0.58	14.56	G1	C1	—	—	—	3	20
C4orf50	01-High	0.58	18.83	G1	C1	T.CD8_Tem.motility_primed (L2)	EPI.pancreatic_islet (Tier: relevant)	78 cells — complete matches	3	20
RPSAP52.2	01-High	0.57	10.83	G1	C1	—	—	—	13	47
HMGA2	01-High	0.57	10.20	G1	C1	—	induced_pluripotent_stem_cell (Tier: relevant) IPSC.induced_pluripotent_stem_cell (Tier: relevant)	34 cells — complete matches	13	47
PROX1	01-High	0.57	10.91	G1	C1	EC.lymphatic (L1S)	HEP.acute_phase (Tier: specific) EPI.pancreatic_acinar.adhesion_remodeling (Tier: relevant) EPI.pancreatic_ductal_bicarbonate.renewal_ion_pump (Tier: relevant) HEP.acute_phase.proliferative (Tier: relevant)	49 cells — complete matches	30	80
ENSG00000290803	01-High	0.56	16.98	G1	C1	—	—	—	3	20
RAB1A	01-High	0.56	6.63	G1	C1	—	—	—	50	188
PPP2R2C	01-High	0.56	13.98	G1	C1	—	EPI.pancreatic_islet (Tier: relevant)	EPI.pancreatic_islet (L1S)	3	20
ENSG00000300592	01-High	0.56	6.40	G1	C1	—	—	—	49	183
MICB	01-High	0.54	7.87	G1	C1	—	—	43 cells — complete matches	294	633
COBLL1	01-High	0.54	16.01	G1	C1	EPI.renal_distal_tubule.immune_modulatory (L2), NEU.EXC_IT.neuromodulated (L2)	HEP.periportal_metabolic (Tier: specific)	48 cells — complete matches	88	614
ENSG00000308279	01-High	0.53	10.54	G1	C1	—	—	—	8	18
ENSG00000298675	01-High	0.53	10.73	G1	C1	—	—	—	7	16
ENSG00000288588	01-High	0.53	11.92	G1	C1	—	—	—	3	14
PARP11-AS1	01-High	0.51	9.56	G1	C1	—	—	—	8	26
ENSG00000256969	01-High	0.51	9.27	G1	C1	—	—	—	7	27
PROX1-AS1	01-High	0.51	7.70	G1	C1	—	—	—	28	73
HMGA2-AS1	01-High	0.51	8.87	G1	C1	—	—	—	13	44
ENSG00000274895	01-High	0.50	8.32	G1	C1	—	—	—	19	57
ENSG00000298091	01-High	0.50	7.60	G1	C1	—	—	—	8	17
ENSG00000298123	01-High	0.50	9.60	G1	C1	—	—	—	8	16
ENSG00000256083	01-High	0.50	11.29	G1	C1	—	—	—	13	44
ENSG00000296658	01-High	0.49	6.27	G1	C1	—	—	—	6	16
MACF1	01-High	0.49	12.12	G1	C1	EPI.salivary_serous_acinar.quiescent (L2), OPC.homeostatic (L2), SMC.contractile (L2)	EPI.salivary_serous_acinar.quiescent (Tier: specific)	27 cells — complete matches	74	406
LAMC1	01-High	0.48	6.87	G1	C1	ADIPO.thermogenic (L2)	—	24 cells — complete matches	60	136
TIGAR	01-High	0.48	5.33	G1	C1	—	—	10 cells — complete matches	6	17
ENSG00000304812	01-High	0.48	7.88	G1	C1	—	—	—	13	44
LINC02454	01-High	0.48	8.25	G1	C1	—	—	8 cells — complete matches	14	44
ENSG00000305724	01-High	0.48	5.32	G1	C1	—	—	—	6	16
PARP11	01-High	0.48	7.60	G1	C1	—	—	8 cells — complete matches	13	51
NOSTRIN	01-High	0.47	4.34	G1	C1	EC.liver_sinusoidal.secretory_lipoprotein (L2)	EPI.salivary_serous_acinar.seromucous_like (Tier: relevant)	47 cells — complete matches	13	43
MSRB3-AS1	01-High	0.47	7.58	G1	C1	—	—	—	13	44
JAKMIP1	01-High	0.47	8.62	G1	C1	T.CD8_Tem.motility_primed (L2)	EPI.pancreatic_islet (Tier: relevant)	77 cells — complete matches	3	20
C12orf43	01-High	0.47	6.90	G1	C1	—	—	6 cells — complete matches	90	178
HNF1A-AS1	01-High	0.47	5.17	G1	C1	—	—	—	191	580
ENSG00000305873	01-High	0.47	6.93	G1	C1	—	—	—	7	26
STK19	01-High	0.46	3.88	G1	C1	—	—	12 cells — complete matches	35	52
ENSG00000238221	01-High	0.45	11.77	G1	C1	—	—	—	53	141
ENSG00000213970	01-High	0.44	3.95	G1	C1	—	—	—	6	16
ENSG00000293166	01-High	0.44	3.95	G1	C1	—	—	—	6	16
ENSG00000225233	01-High	0.44	7.33	G1	C1	—	—	—	17	51
ENSG00000287497	01-High	0.44	10.99	G1	C1	—	—	—	44	97
ENSG00000225092	01-High	0.44	11.01	G1	C1	—	—	—	64	160
ENSG00000285771	01-High	0.43	11.66	G1	C1	—	—	—	44	106
CEP68	01-High	0.43	7.13	G1	C1	—	—	10 cells — complete matches	50	180
FGF23	01-High	0.43	3.56	G1	C1	EC.liver_sinusoidal.hypoxia_metabolic (L2)	—	6 cells — complete matches	6	17
LINC02245	01-High	0.43	6.39	G1	C1	—	—	23 cells — complete matches	50	180
ENSG00000303446	01-High	0.43	11.46	G1	C1	—	—	—	41	84
CTRB2	01-High	0.42	4.19	G1	C1	EPI.pancreatic_acinar (L1S), EPI.pancreatic_acinar.baseline (L2), EPI.pancreatic_ductal_progenitor.ADM_like (L2)	EPI.pancreatic_acinar (Tier: specific) EPI.pancreatic_ductal_progenitor (Tier: specific) EPI.pancreatic_ductal_perivascular (Tier: relevant) EPI.pancreatic_acinar.adhesion_remodeling (Tier: relevant) EPI.pancreatic_acinar.inflammatory_regenerative (Tier: relevant) EPI.pancreatic_ductal_perivascular.baseline (Tier: relevant) EPI.pancreatic_ductal_perivascular.protective_antioxidant (Tier: relevant) EPI.pancreatic_ductal_progenitor.baseline (Tier: relevant) EPI.pancreatic_ductal_progenitor.ciliated_transport (Tier: relevant)	16 cells — complete matches	32	49
LINC02576	01-High	0.42	6.96	G1	C1	—	—	—	47	176
ENSG00000226281	01-High	0.42	9.30	G1	C1	—	—	—	51	113
ENSG00000280152	01-High	0.42	2.45	G1	C1	—	—	—	24	23
DMGDH	01-High	0.41	6.87	G1	C1	EPI.pancreatic_acinar.metabolic_onecarbon (L2)	MONO.CD14.cord_tolerance (Tier: relevant)	26 cells — complete matches	38	113
IRS2	01-High	0.41	6.29	G1	C1	T.CD4_Th2.tissue_adapted (L2)	adipocyte (Tier: relevant) ADIPO.adipocyte (Tier: relevant) ADIPO.hypoxia_remodelling (Tier: relevant) EPI.intrahepatic_cholangiocyte_transport.protease_shield_hippo (Tier: relevant)	29 cells — complete matches	17	64
LINC02775	01-High	0.41	5.84	G1	C1	—	—	—	24	68
ENSG00000308551	01-High	0.41	3.18	G1	C1	—	—	—	6	17
LAMC2	01-High	0.41	6.77	G1	C1	EPI.extrahepatic_cholangiocyte.barrier_interface (L2), EPI.hepatic_ductular_cholangiocyte.barrier_chemokine (L2), EPI.skin_follicular_keratinizing.root_infundibulum (L2)	EPI.intrahepatic_cholangiocyte_transport.protease_shield_hippo (Tier: relevant)	58 cells — complete matches	56	134
JMY	01-High	0.41	6.21	G1	C1	—	—	19 cells — complete matches	27	80
FERRY3	01-High	0.40	2.81	G1	C1	—	—	—	4	10
SLC1A4	01-High	0.40	6.13	G1	C1	ASTRO.homeostatic (L2)	—	54 cells — complete matches	48	177
ENSG00000300524	01-High	0.40	5.98	G1	C1	—	—	—	18	63
ENSG00000275741	01-High	0.40	5.90	G1	C1	—	—	—	16	59
ENSG00000223342	01-High	0.40	9.56	G1	C1	—	—	—	23	43
ACTR2	01-High	0.40	8.14	G1	C1	—	—	FIB.hepatic_stellate_cell.fibrogenic (L2)	53	188
ENSG00000261211	01-High	0.40	9.28	G1	C1	—	—	—	47	112
SPC25	01-High	0.39	5.80	G1	C1	EPI.pancreatic_islet.alpha (L2), IPSC.proliferative (L2)	HEP.acute_phase.proliferative (Tier: relevant)	46 cells — complete matches	13	44
ENSG00000309364	01-High	0.39	8.47	G1	C1	—	—	—	53	132
RAD51AP1	01-High	0.39	2.71	G1	C1	EPI.pancreatic_ductal_mucinous.proliferative_gastric_like (L2), EPI.skin_interfollicular_spinous.proliferative (L2)	EPI.pancreatic_ductal_mucinous.proliferative_gastric_like (Tier: relevant) HEP.acute_phase.proliferative (Tier: relevant)	50 cells — complete matches	2	2
ENSG00000240338	01-High	0.39	4.94	G1	C1	—	—	—	40	58
ENSG00000290455	01-High	0.39	4.94	G1	C1	—	—	—	40	58
CTRB1	01-High	0.38	4.55	G1	C1	EPI.pancreatic_acinar.baseline (L2)	EPI.pancreatic_acinar (Tier: specific) EPI.pancreatic_ductal_progenitor (Tier: specific) EPI.pancreatic_ductal_perivascular (Tier: relevant) EPI.pancreatic_acinar.adhesion_remodeling (Tier: relevant) EPI.pancreatic_acinar.inflammatory_regenerative (Tier: relevant) EPI.pancreatic_ductal_perivascular.baseline (Tier: relevant) EPI.pancreatic_ductal_perivascular.protective_antioxidant (Tier: relevant) EPI.pancreatic_ductal_progenitor.baseline (Tier: relevant) EPI.pancreatic_ductal_progenitor.ciliated_transport (Tier: relevant)	22 cells — complete matches	42	59
SHCBP1L	01-High	0.38	6.70	G1	C1	—	—	7 cells — complete matches	33	97
ENSG00000300479	01-High	0.37	4.50	G1	C1	—	—	—	45	177
ENSG00000293332	01-High	0.37	5.41	G1	C1	—	—	—	48	177
ENSG00000303716	01-High	0.36	6.24	G1	C1	—	—	—	37	104
ENSG00000300543	01-High	0.36	5.73	G1	C1	—	—	—	2	3
CFDP1	01-High	0.35	2.37	G1	C1	—	—	T.CD8_Tem.motility_primed (L2)	28	31
ENSG00000261783	01-High	0.35	2.14	G1	C1	—	—	—	23	23
ENSG00000305666	01-High	0.35	4.47	G1	C1	—	—	—	47	111
NMNAT2	01-High	0.34	3.65	G1	C1	—	EPI.pancreatic_islet (Tier: relevant)	27 cells — complete matches	56	121
ENSG00000285534	01-High	0.34	4.33	G1	C1	—	—	—	18	63
ENSG00000308820	01-High	0.33	4.67	G1	C1	—	—	—	2	3
MYO16	01-High	0.32	4.72	G1	C1	—	—	19 cells — complete matches	17	63
ENSG00000306568	01-High	0.32	4.71	G1	C1	—	—	—	15	55
ENSG00000296114	01-High	0.32	1.70	G1	C1	—	—	—	19	20
ENSG00000287575	01-High	0.32	6.22	G1	C1	—	—	—	18	71
ENSG00000296995	01-High	0.30	3.94	G1	C1	—	—	—	2	3
ENSG00000295795	01-High	0.30	5.20	G1	C1	—	—	—	19	70
ENSG00000309005	01-High	0.30	2.64	G1	C1	—	—	—	2	3
ENSG00000301741	01-High	0.30	2.79	G1	C1	—	—	—	16	60
ENSG00000295202	01-High	0.30	3.46	G1	C1	—	—	—	2	3
ENSG00000300610	01-High	0.30	0.80	G1	C1	—	—	—	8	16
LINC03082	01-High	0.30	4.34	G1	C1	—	—	—	18	69
ENSG00000301029	01-High	0.29	3.30	G1	C1	—	—	—	18	63
ENSG00000294610	01-High	0.29	2.99	G1	C1	—	—	—	2	3
ENSG00000295255	01-High	0.29	4.32	G1	C1	—	—	—	2	3
LINC00370	01-High	0.29	2.45	G1	C1	—	—	11 cells — complete matches	2	1
ENSG00000303952	01-High	0.28	2.72	G1	C1	—	—	—	2	3
MYO16-AS1	01-High	0.28	3.47	G1	C1	—	—	—	1	1
ENSG00000289901	01-High	0.27	2.86	G1	C1	—	—	—	4	3
PNPLA3	02-Medium	0.61	17.11	G1	C2	GRANU.MAST.resting_granule (L2)	adipocyte (Tier: relevant) ADIPO.adipocyte (Tier: relevant) ADIPO.hypoxia_remodelling (Tier: relevant) ADIPO.inflammatory (Tier: relevant)	17 cells — complete matches	251	496
UBE3C	02-Medium	0.59	15.74	G1	C2	—	—	7 cells — complete matches	3	14
ENSG00000304926	02-Medium	0.58	14.92	G1	C2	—	—	—	251	496
HLA-DQB1	02-Medium	0.58	22.28	G1	C2	MONO.CD14.APC_like (L2), PC.IgG_systemic.stress (L2), T.CD4_Tcm.APC_mimicry (L2), T.CD4_Treg.APC_interactive (L2), T.CD4_transitional.APC_interacting (L2), T.CD8_transitional.APC_like (L2)	—	133 cells — complete matches	703	1,314
PPARG	02-Medium	0.57	11.22	G1	C2	MAC.alveolar (L1S), DC.cDC2.lipid_metabolic (L2), EPI.skin_appendage_keratinocyte.sebaceous_apocrine (L2), GRNLSA.chemokine_mechanosensory (L2), MAC.resident_cardiac.inflammatory_reparative (L2)	adipocyte (Tier: relevant) ADIPO.adipocyte (Tier: relevant) ADIPO.hypoxia_remodelling (Tier: relevant) ADIPO.inflammatory (Tier: relevant)	78 cells — complete matches	122	460
ENSG00000280087	02-Medium	0.57	5.86	G1	C2	—	—	—	359	1,576
ENSG00000233547	02-Medium	0.56	20.53	G2	C1	—	—	—	15	39
ENSG00000295020	02-Medium	0.56	13.25	G1	C2	—	—	—	6	16
LINC01948	02-Medium	0.56	12.88	G1	C2	EPI.pancreatic_ductal_bicarbonate.baseline (L2)	EPI.pancreatic_ductal_bicarbonate.renewal_ion_pump (Tier: relevant)	31 cells — complete matches	4	12
HLA-A	02-Medium	0.56	7.02	G1	C2	EPI.hepatic_ductular_cholangiocyte.barrier_chemokine (L2), EPI.intrahepatic_cholangiocyte_defense.secretory_barrier (L2), EPI.intrahepatic_cholangiocyte_transport.protease_shield_hippo (L2), EPI.renal_principal_cell.injury_repair (L2), EPI.skin_appendage_keratinocyte.ductal_immune_interacting (L2), FIB.skin_sheath.ECM_immune (L2), HEP.pericentral_lipoprotein.ApoB_coagulation (L2), NEU.EXC_CT.remodeling (L2), OPC.proliferative_immune_interact (L2)	HEP.periportal_metabolic.apolipoprotein_secretory (Tier: relevant)	78 cells — complete matches	281	510
KCNJ11	02-Medium	0.55	11.96	G1	C2	—	—	DC.cDC1.baseline (L2), PC.IgG_systemic.secretory (L2)	6	16
ENSG00000307907	02-Medium	0.55	12.84	G1	C2	—	—	—	489	1,000
TCF7L2	02-Medium	0.55	20.93	G2	C1	MAC.MDM.inflammatory_phagocytic (L2)	—	19 cells — complete matches	24	62
GRB14	02-Medium	0.55	16.92	G2	C1	EPI.hepatic_ductular_cholangiocyte.polarity (L2), EPI.renal_distal_tubule.ciliated_remodelling (L2), GRANU.neutrophil.antiviral_endotoxin (L2), NEU.EXC_IT.callosal (L2)	HEP.periportal_metabolic (Tier: specific) HEP.periportal_metabolic.urea_onecarbon_secretory (Tier: specific) adipocyte (Tier: relevant) ADIPO.adipocyte (Tier: relevant) ADIPO.hypoxia_remodelling (Tier: relevant) GRNLSA.EMT_insulin_signaling (Tier: relevant)	37 cells — complete matches	35	131
AP3S2	02-Medium	0.55	13.61	G2	C1	—	—	8 cells — complete matches	12	23
LINC02935	02-Medium	0.55	24.80	G2	C1	—	—	—	4	10
MIR6891	02-Medium	0.54	7.20	G1	C2	—	—	—	474	812
ARAP1	02-Medium	0.54	6.47	G1	C2	—	—	T.CD4_transitional.tissue_enagement (L2)	19	49
ENSG00000286256	02-Medium	0.54	10.97	G1	C2	—	—	—	12	24
ZMIZ1	02-Medium	0.54	14.13	G1	C2	—	MONO.CD14.remodeling (Tier: specific)	27 cells — complete matches	19	63
HLA-DRB1	02-Medium	0.54	13.46	G1	C2	EPI.skin_sebaceous_duct_luminal.immune_interface (L2), FIB.interstitial.mesenchymal_APC (L2), FIB.reticular.immune_interface (L2), MAC.resident_cardiac.antigen_presenting (L2), MAC.resident_repair.antigen_presenting (L2), MG.phagocytic_APC (L2), MONO.CD14.APC_like (L2), NK.adaptive_axis_baseline (L2), NK.adaptive_biosynthetic_primed (L2), NK.adaptive_classII_inhibitory (L2), NK.adaptive_immature_precursor (L2), PC.IgG_systemic.stress (L2), T.CD4_Tcm.APC_mimicry (L2), T.CD4_Tem.cytotoxic_effector (L2), T.CD4_Tfh.effector_migratory (L2), T.CD4_Th17.cytotoxic (L2), T.CD4_Treg.APC_interactive (L2), T.CD4_Trm.cytotoxic_effector (L2), T.CD4_transitional.APC_interacting (L2), T.CD4_transitional.primed_cytotoxic (L2), T.CD8_Trm.dendritic_recruiter (L2), T.CD8_transitional.APC_like (L2), T.MAIT.cytotoxic (L2)	MONO.CD14.remodeling (Tier: specific)	203 cells — complete matches	565	1,192
DLG2	02-Medium	0.54	7.78	G1	C2	EPI.pancreatic_islet.beta (L2)	—	29 cells — complete matches	2	5
HLA-B	02-Medium	0.54	6.50	G1	C2	EC.heart_remodeling.remodeling_stalk (L2), EPI.hepatic_ductular_cholangiocyte.barrier_chemokine (L2), EPI.intrahepatic_cholangiocyte_defense.secretory_barrier (L2), EPI.intrahepatic_cholangiocyte_transport.protease_shield_hippo (L2), EPI.pancreatic_ductal_perivascular.protective_antioxidant (L2), FIB.skin_sheath.ECM_immune (L2), OPC.proliferative_immune_interact (L2), SMC.metabolic (L2)	EPI.pancreatic_ductal_perivascular.protective_antioxidant (Tier: relevant)	130 cells — complete matches	493	836
SYN2	02-Medium	0.53	8.51	G1	C2	—	—	28 cells — complete matches	27	58
ANPEP	02-Medium	0.52	14.03	G1	C2	EPI.pancreatic_acinar.inflammatory_regenerative (L2)	EPI.pancreatic_acinar (Tier: specific) EPI.pancreatic_acinar.inflammatory_regenerative (Tier: relevant)	76 cells — complete matches	13	24
LINC01126	02-Medium	0.52	15.93	G1	C2	—	—	31 cells — complete matches	45	125
ENSG00000289559	02-Medium	0.52	4.04	G1	C2	—	—	—	131	232
DENND1A	02-Medium	0.52	11.68	G1	C2	—	—	16 cells — complete matches	6	6
ZNRD2-DT	02-Medium	0.52	11.17	G1	C2	—	—	—	2	6
MRAS	02-Medium	0.52	8.86	G1	C2	—	MONO.CD14.remodeling (Tier: specific)	38 cells — complete matches	11	29
PNPLA5	02-Medium	0.52	15.82	G1	C2	—	—	—	251	496
ENSG00000293025	02-Medium	0.52	7.00	G1	C2	—	—	—	31	87
ENSG00000299769	02-Medium	0.52	17.08	G1	C2	—	—	—	333	727
HMG20A	02-Medium	0.52	10.91	G1	C2	—	—	B.age_associated.migratory (L2)	0	4
GLP1R	02-Medium	0.51	7.26	G1	C2	—	EPI.pancreatic_acinar (Tier: specific) EPI.pancreatic_islet (Tier: relevant) EPI.pancreatic_ductal_mucinous.proliferative_gastric_like (Tier: relevant) EPI.pancreatic_islet.delta (Tier: relevant)	13 cells — complete matches	2	10
ENSG00000249138	02-Medium	0.51	10.29	G1	C2	—	—	—	8	13
SLED1	02-Medium	0.51	10.29	G1	C2	—	—	—	8	13
ENSG00000294808	02-Medium	0.51	11.07	G1	C2	—	—	—	12	48
ZNRD2	02-Medium	0.51	11.07	G1	C2	—	—	—	12	48
HLA-DQA1	02-Medium	0.51	15.21	G1	C2	EPI.skin_sebaceous_duct_luminal.immune_interface (L2), MAC.resident_iron.APC_iron_sensing (L2), MONO.CD14.APC_like (L2), MONO.CD16.hepatic_mac_like (L2), NK.adaptive_classII_inhibitory (L2), NK.adaptive_immature_precursor (L2), PC.IgG_systemic.stress (L2), T.CD4_Tem.cytotoxic_effector (L2), T.CD4_Treg.APC_interactive (L2), T.CD4_Trm.metal_stress (L2), T.CD4_transitional.APC_interacting (L2), T.CD8_Trm.dendritic_recruiter (L2), T.CD8_transitional.APC_like (L2)	—	159 cells — complete matches	608	1,232
SSR1	02-Medium	0.51	12.13	G1	C2	—	—	B.memory.pDC_imprint (L2), EC.venous.remodeling_stalk (L2)	35	61
ACSL1	02-Medium	0.51	10.94	G1	C2	EPI.ectocervical_granular.inflammatory (L2), HEP.canalicular_transport.inflammatory (L2)	adipocyte (Tier: relevant) ADIPO.adipocyte (Tier: relevant) ADIPO.hypoxia_remodelling (Tier: relevant) MONO.CD14.cord_tolerance (Tier: relevant)	25 cells — complete matches	12	24
CFB	02-Medium	0.51	3.10	G1	C2	EPI.hepatic_ductular_cholangiocyte.acute_phase_complement (L2), MAC.LAM.lipid_opsonization (L2), MAC.alveolar.scavenging_endocytic (L2), MAC.resident_repair.ECM_stromal_crosstalk (L2)	HEP.acute_phase (Tier: specific) HEP.acute_phase.complement_metabolic (Tier: specific) HEP.periportal_metabolic.urea_onecarbon_secretory (Tier: specific) EPI.pancreatic_ductal_perivascular.protective_antioxidant (Tier: relevant) HEP.acute_phase.proliferative (Tier: relevant) HEP.periportal_metabolic.apolipoprotein_secretory (Tier: relevant)	94 cells — complete matches	508	1,239
HLA-DRA	02-Medium	0.51	14.06	G1	C2	B_cell (L1), dendritic_cell (L1), DC.mig (L1S), EC.capillary.postcap_venule (L2), EPI.renal_distal_tubule.stress (L2), EPI.skin_sebaceous_duct_luminal.immune_interface (L2), FIB.interstitial.mesenchymal_APC (L2), MAC.resident_repair.antigen_presenting (L2), MONO.CD14.APC_like (L2), PC.IgG_systemic.stress (L2), T.CD4_Tcm.APC_mimicry (L2), T.CD4_transitional.APC_interacting (L2), T.CD8_transitional.APC_like (L2)	MONO.CD14.remodeling (Tier: specific)	194 cells — complete matches	693	1,237
ENSG00000310474	02-Medium	0.51	6.92	G1	C2	—	—	—	16	19
GCKR	02-Medium	0.50	6.53	G1	C2	—	hepatocyte (Tier: specific)	22 cells — complete matches	587	1,789
ENSG00000302994	02-Medium	0.50	16.44	G1	C2	—	—	—	354	697
SAMM50	02-Medium	0.50	14.41	G1	C2	—	—	6 cells — complete matches	256	506
GPSM1	02-Medium	0.50	11.00	G1	C2	—	—	14 cells — complete matches	51	202
CLIC1	02-Medium	0.50	9.09	G1	C2	PC.IgG_systemic.secretory (L2)	—	10 cells — complete matches	159	256
NOTCH4	02-Medium	0.50	10.12	G1	C2	—	—	36 cells — complete matches	143	264
ENSG00000271581	02-Medium	0.50	6.91	G1	C2	—	—	—	348	596
ENSG00000235070	02-Medium	0.50	17.33	G1	C2	—	—	—	5	5
DNLZ	02-Medium	0.50	10.78	G1	C2	—	—	14 cells — complete matches	58	218
ENSG00000285647	02-Medium	0.50	6.78	G1	C2	—	—	—	364	611
NCR3	02-Medium	0.49	8.84	G1	C2	T.CD4_transitional.tissue_enagement (L2), T.CD8_Tcm.NK_like (L2), T.CD8_Tem.TEMRA (L2)	—	104 cells — complete matches	261	542
LTBP3	02-Medium	0.49	11.58	G1	C2	—	—	NK.adaptive_adipose_stress (L2)	20	57
ARPIN-AP3S2	02-Medium	0.49	14.22	G2	C2	—	—	—	10	21
UBE2E2	02-Medium	0.49	16.14	G2	C2	—	—	6 cells — complete matches	0	0
ENSG00000285761	02-Medium	0.49	4.67	G1	C2	—	—	—	123	218
HLA-F-AS1	02-Medium	0.49	5.02	G1	C2	—	—	—	199	357
ENSG00000303029	02-Medium	0.49	14.48	G1	C2	—	—	—	234	380
ENSG00000309733	02-Medium	0.49	14.67	G1	C2	—	—	—	468	929
C2CD4A	02-Medium	0.49	8.61	G1	C2	—	—	12 cells — complete matches	13	24
HLA-H	02-Medium	0.49	6.29	G1	C2	—	—	—	204	363
HLA-H.2	02-Medium	0.49	6.29	G1	C2	—	—	—	204	363
ENSG00000272236	02-Medium	0.49	4.62	G1	C2	—	—	—	38	69
BHMT2	02-Medium	0.49	5.87	G1	C2	—	hepatocyte (Tier: specific)	40 cells — complete matches	37	104
TIMP4	02-Medium	0.48	8.67	G1	C2	—	—	43 cells — complete matches	52	199
ENSG00000289701	02-Medium	0.48	9.96	G1	C2	—	—	—	65	255
ENSG00000227766	02-Medium	0.48	6.59	G1	C2	—	—	—	167	362
ENSG00000230521	02-Medium	0.48	6.52	G1	C2	—	—	—	19	28
CDKAL1	02-Medium	0.48	19.12	G2	C2	—	—	8 cells — complete matches	3	3
POLR1HASP.2	02-Medium	0.48	6.40	G1	C2	—	—	—	341	670
ATP6V1G2-DDX39B	02-Medium	0.48	7.50	G2	C1	—	—	11 cells — complete matches	69	185
CDKN1C	02-Medium	0.48	15.40	G1	C2	—	EPI.intrahepatic_cholangiocyte_transport.protease_shield_hippo (Tier: relevant) IPSC.endoderm_primed (Tier: relevant) IPSC.midbrain_primed (Tier: relevant) IPSC.stress (Tier: relevant)	47 cells — complete matches	12	23
SAPCD1-AS1	02-Medium	0.48	8.09	G1	C2	—	—	MAC.LAM.perivascular_angiocrine (L2)	27	56
CDC123	02-Medium	0.48	14.36	G1	C2	—	—	T.CD4_cytotoxic.precursor (L2)	2	4
ENSG00000300558	02-Medium	0.48	8.92	G1	C2	—	—	—	54	209
ENSG00000307670	02-Medium	0.48	7.86	G1	C2	—	—	—	9	17
BMP8A	02-Medium	0.48	9.56	G1	C2	—	—	5 cells — complete matches	13	19
ENSG00000289047	02-Medium	0.48	4.37	G1	C2	—	—	—	248	377
ENSG00000306694	02-Medium	0.47	7.70	G2	C1	—	—	—	2	3
HCG9	02-Medium	0.47	6.94	G1	C2	—	—	10 cells — complete matches	46	80
MSH5-SAPCD1	02-Medium	0.47	9.70	G2	C1	—	—	15 cells — complete matches	7	13
FBXW7	02-Medium	0.47	5.47	G1	C2	EPI.skin_sweat_duct_keratinocyte.signal_gate (L2)	EPI.salivary_serous_acinar.quiescent (Tier: specific)	22 cells — complete matches	6	13
ATP6V1G2	02-Medium	0.47	6.84	G2	C1	—	—	12 cells — complete matches	73	194
ENSG00000294060	02-Medium	0.47	10.58	G1	C2	—	—	—	31	97
HCP5	02-Medium	0.47	7.46	G1	C2	—	—	—	510	867
HAPLN4	02-Medium	0.47	5.78	G1	C2	—	—	9 cells — complete matches	30	97
ENSG00000267629	02-Medium	0.47	5.77	G1	C2	—	—	—	55	149
ENSG00000290574	02-Medium	0.47	6.45	G1	C2	—	—	—	55	94
ENSG00000295286	02-Medium	0.47	7.58	G1	C2	—	—	—	5	9
HNF1A	02-Medium	0.47	4.45	G1	C2	—	—	—	170	486
MSH5	02-Medium	0.47	8.92	G2	C1	—	—	13 cells — complete matches	7	14
SNF8	02-Medium	0.46	7.20	G1	C2	—	—	B.naive.proteostasis (L2), MAC.resident_iron.heme_catabolism (L2)	21	62
TM6SF2	02-Medium	0.46	5.26	G1	C2	—	—	25 cells — complete matches	55	149
ARPIN	02-Medium	0.46	14.24	G2	C2	—	MONO.CD14.remodeling (Tier: specific)	23 cells — complete matches	10	21
ENSG00000230532	02-Medium	0.46	6.91	G1	C2	—	—	—	21	62
BHMT	02-Medium	0.46	5.96	G1	C2	EPI.renal_proximal_tubule.onecarbon_peroxisome (L2)	HEP.periportal_metabolic (Tier: specific) HEP.periportal_metabolic.inflammatory_activated (Tier: specific) HEP.periportal_metabolic.urea_onecarbon_secretory (Tier: specific) HEP.acute_phase.proliferative (Tier: relevant) HEP.periportal_metabolic.apolipoprotein_secretory (Tier: relevant) HEP.periportal_metabolic.stress_chaperone (Tier: relevant)	18 cells — complete matches	36	102
ENSG00000251139	02-Medium	0.46	11.28	G1	C2	—	—	—	8	12
KLHL21	02-Medium	0.46	7.52	G1	C2	—	—	25 cells — complete matches	7	11
WBP1L	02-Medium	0.46	7.49	G1	C2	—	—	11 cells — complete matches	23	66
TH	02-Medium	0.46	10.08	G2	C2	NEU.INH_PVALB.serotonergic (L2)	—	13 cells — complete matches	35	118
RCCD1	02-Medium	0.46	8.68	G2	C1	—	—	15 cells — complete matches	3	8
CENPW	02-Medium	0.46	4.51	G1	C2	DC.cDC1.proliferative (L2), EPI.ileal_enterocyte_crypt.proliferative_G2M (L2), IPSC.proliferative (L2), THYMO.proliferative_S (L2)	—	46 cells — complete matches	17	39
FAM89B	02-Medium	0.45	11.08	G2	C2	—	—	15 cells — complete matches	3	6
EHBP1L1	02-Medium	0.45	11.39	G1	C2	—	—	25 cells — complete matches	35	161
PPP1R1B	02-Medium	0.45	6.45	G1	C2	EPI.renal_thick_ascending_limb.cation_flux (L2), EPI.tracheal_submucosal_gland.acinar_serous (L2)	EPI.pancreatic_ductal_progenitor (Tier: specific) EPI.salivary_serous_acinar.quiescent (Tier: specific) EPI.pancreatic_ductal_progenitor.baseline (Tier: relevant) EPI.pancreatic_ductal_progenitor.ciliated_transport (Tier: relevant)	47 cells — complete matches	18	57
ENSG00000286445	02-Medium	0.45	7.08	G1	C2	—	—	—	7	19
TFEB	02-Medium	0.45	6.44	G1	C2	—	—	28 cells — complete matches	32	141
UBE2Z	02-Medium	0.45	6.72	G1	C2	—	—	B.naive.receptor_recycle (L2), EC.arterial.elastic (L2), T.CD4_naive.survival_neddylation (L2)	32	86
LINC02569	02-Medium	0.45	7.60	G1	C2	—	—	—	41	82
ZNF513	02-Medium	0.45	4.70	G2	C1	—	—	15 cells — complete matches	268	632
APOE	02-Medium	0.45	5.18	G1	C2	macrophage (L1), HEP.pericentral_lipoprotein (L1S), MAC.LAM (L1S), MAC.microglia_like (L1S), ASPC.adipocyte_capillary_interface (L2), EPI.ectocervical_granular.secretory_apocrine (L2), EPI.renal_intercalated_cell_type_A.acid_secretion (L2), EPI.skin_appendage_keratinocyte.sebaceous_apocrine (L2), EPI.skin_hair_follicle_bulge.niche_crosstalk (L2), EPI.skin_keratinocyte_progenitor.quiescent_stem_like (L2), EPI.skin_keratinocyte_proliferating.early_spinous_transition (L2), FIB.interstitial.lipid_matrix (L2), FIB.perivascular_interface.lipid_shuttle (L2), FIB.suburothelial.homeostasis_matrix (L2), FIB.transitioning.ISG_primed_interface (L2), HEP.acute_phase.stress_secretory (L2), HEP.periportal_metabolic.apolipoprotein_secretory (L2), MAC.LAM.inflammatory_APC (L2), MAC.MDM.LAM_like (L2), MAC.resident_repair.lipid_phagocytic (L2), MG.phagocytic_APC (L2), NEU.INH_LAMP5.glial_interface (L2)	EPI.pancreatic_ductal_perivascular (Tier: relevant) EPI.pancreatic_ductal_perivascular.baseline (Tier: relevant) EPI.pancreatic_ductal_perivascular.protective_antioxidant (Tier: relevant) GRNLSA.EMT_insulin_signaling (Tier: relevant) HEP.periportal_metabolic.apolipoprotein_secretory (Tier: relevant) IPSC.endoderm_primed (Tier: relevant)	163 cells — complete matches	351	1,543
UBE2E2-DT	02-Medium	0.45	12.74	G2	C2	—	—	—	0	0
TRIM8-DT	02-Medium	0.45	4.93	G1	C2	—	—	—	16	42
TRIM8	02-Medium	0.45	5.50	G1	C2	—	—	4 cells — complete matches	29	67
ENSG00000304061	02-Medium	0.45	11.08	G1	C2	—	—	—	9	12
ENSG00000289197	02-Medium	0.45	10.64	G1	C2	—	—	—	8	13
ATG16L2	02-Medium	0.45	5.75	G1	C2	—	MONO.CD14.remodeling (Tier: specific)	18 cells — complete matches	17	29
ENSG00000297540	02-Medium	0.45	16.59	G1	C2	—	—	—	0	0
ENSG00000289139	02-Medium	0.45	10.90	G1	C2	—	—	—	8	13
FAM99B	02-Medium	0.45	10.49	G2	C1	—	—	—	29	101
ENSG00000293944	02-Medium	0.45	16.48	G1	C2	—	—	—	0	0
ANK1	02-Medium	0.45	14.21	G2	C2	—	EPI.pancreatic_ductal_mucinous.proliferative_gastric_like (Tier: relevant)	60 cells — complete matches	1	10
CENPU	02-Medium	0.45	7.47	G2	C2	DC.cDC2.proliferative (L2), HEP.acute_phase.proliferative (L2), THYMO.proliferative_S (L2)	HEP.acute_phase.proliferative (Tier: relevant)	46 cells — complete matches	9	17
MINPP1	02-Medium	0.45	4.99	G1	C2	HPC.MEP (L2)	—	10 cells — complete matches	9	20
HLA-DQB2	02-Medium	0.45	5.98	G1	C2	—	—	60 cells — complete matches	205	497
EIF2AK4	02-Medium	0.45	6.05	G2	C1	—	—	8 cells — complete matches	8	21
MIR3945HG	02-Medium	0.44	9.71	G1	C2	—	MONO.CD14.remodeling (Tier: specific) MONO.CD14.cord_tolerance (Tier: relevant)	65 cells — complete matches	12	29
BRD3	02-Medium	0.44	6.38	G2	C1	—	—	8 cells — complete matches	6	17
MICB-DT	02-Medium	0.44	6.90	G1	C2	—	—	—	131	286
ENSG00000233902	02-Medium	0.44	5.19	G1	C2	—	—	—	150	247
MED1	02-Medium	0.44	7.80	G1	C2	—	—	14 cells — complete matches	5	17
EIF2B4	02-Medium	0.44	4.62	G1	C2	—	—	5 cells — complete matches	287	671
SNX17	02-Medium	0.44	4.58	G1	C2	—	—	MAC.kupffer.tolerogenic (L2)	268	632
LINC01093	02-Medium	0.44	9.59	G1	C2	—	HEP.acute_phase (Tier: specific) HEP.acute_phase.complement_metabolic (Tier: specific) HEP.periportal_metabolic.urea_onecarbon_secretory (Tier: specific) MONO.CD14.remodeling (Tier: specific)	17 cells — complete matches	9	14
DDX39B	02-Medium	0.44	5.91	G1	C2	—	—	—	112	383
EIF4G1	02-Medium	0.44	9.70	G2	C2	—	—	T.CD4_transitional.APC_interacting (L2)	1	1
ACTA1	02-Medium	0.44	5.70	G1	C2	skeletal_muscle_cell (L1), SKM.type_2_fast (L1S)	—	39 cells — complete matches	1	6
MIR3945	02-Medium	0.44	9.53	G1	C2	—	—	—	11	19
PPIEL.2	02-Medium	0.44	10.33	G2	C1	—	—	—	4	7
TOMM40	02-Medium	0.44	7.82	G1	C2	—	—	DC.cDC2.monocyte_like (L2), EPI.ileal_goblet.immature (L2)	296	1,418
NEGR1	02-Medium	0.44	11.71	G2	C2	—	EPI.pancreatic_islet.delta (Tier: relevant)	73 cells — complete matches	5	12
LINC02437	02-Medium	0.43	8.56	G1	C2	—	—	8 cells — complete matches	7	9
LPIN3	02-Medium	0.43	8.74	G2	C2	—	—	16 cells — complete matches	53	140
LINC02708	02-Medium	0.43	10.19	G2	C1	—	—	—	24	88
MAP3K11	02-Medium	0.43	9.43	G1	C2	—	—	B.age_associated.naive_transitional (L2), EC.lymphatic.activated (L2), T.CD4_Tcm.migratory_cilium (L2)	55	235
VASH1	02-Medium	0.43	5.71	G1	C2	—	MONO.CD14.remodeling (Tier: specific)	53 cells — complete matches	9	6
COL4A2	02-Medium	0.43	10.29	G1	C2	ASPC.adipocyte_capillary_interface (L2), EC.arterial.angiogenic_tip (L2), EC.venous.remodeling_stalk (L2), FIB.transitioning.matrix_stress (L2), PC.IgA_muocsal.baseline (L2)	adipocyte (Tier: relevant) ADIPO.adipocyte (Tier: relevant) ADIPO.hypoxia_remodelling (Tier: relevant) EPI.intrahepatic_cholangiocyte_transport.protease_shield_hippo (Tier: relevant)	70 cells — complete matches	31	70
SRP14-DT	02-Medium	0.43	6.34	G1	C2	—	—	—	2	7
ENSG00000305816	02-Medium	0.43	4.23	G1	C2	—	—	—	12	23
KRTCAP3	02-Medium	0.43	4.43	G1	C2	—	—	30 cells — complete matches	186	569
ERBB2	02-Medium	0.43	4.17	G1	C2	HEP.periportal_metabolic.urea_onecarbon_secretory (L2)	HEP.periportal_metabolic (Tier: specific) HEP.periportal_metabolic.urea_onecarbon_secretory (Tier: specific)	6 cells — complete matches	26	72
PLCG1	02-Medium	0.43	10.24	G2	C2	—	—	31 cells — complete matches	21	43
LINC02796	02-Medium	0.43	11.12	G1	C2	—	—	—	46	121
AUTS2	02-Medium	0.43	14.94	G2	C2	—	EPI.salivary_serous_acinar.quiescent (Tier: specific)	43 cells — complete matches	2	6
ENSG00000259081	02-Medium	0.43	5.35	G1	C2	—	—	—	3	0
TRIM31-AS1	02-Medium	0.43	4.24	G1	C2	—	—	6 cells — complete matches	56	83
NUCB2	02-Medium	0.43	7.69	G2	C2	EPI.bile_duct_cholangiocyte.secretory_mucin (L2), EPI.salivary_serous_acinar.secretory_active (L2), HEP.canalicular_transport.secretory_ERAD_UPR (L2), T.CD8_Tcm.baseline (L2)	—	33 cells — complete matches	6	5
TCF4	02-Medium	0.43	9.73	G2	C2	DC.pDC (L1S), DC.pDC.baseline (L2), FIB.barrier_purinergic.lipid_secretory (L2), FIB.transitioning.secretory_procollagen (L2), NEU.EXC_CT.projector (L2), SMC.metabolic (L2)	—	62 cells — complete matches	9	17
HLA-DRB5	02-Medium	0.43	14.22	G1	C2	EC.venous.baseline (L2), EPI.endocervical_secretory.secretory_translocon (L2), EPI.skin_sebaceous_duct_luminal.immune_interface (L2), FIB.interstitial.mesenchymal_APC (L2), MG.phagocytic_APC (L2), NK.adaptive_classII_inhibitory (L2), PC.IgG_systemic.stress (L2), T.CD4_Tcm.APC_mimicry (L2), T.CD4_Treg.APC_interactive (L2), T.CD4_Trm.cytotoxic_effector (L2), T.CD4_transitional.APC_interacting (L2), T.CD8_transitional.APC_like (L2), T.MAIT.cytotoxic (L2)	MONO.CD14.remodeling (Tier: specific)	193 cells — complete matches	364	756
RREB1	02-Medium	0.43	10.24	G2	C2	—	—	16 cells — complete matches	63	158
HLA-DOB	02-Medium	0.43	9.86	G2	C2	—	—	64 cells — complete matches	135	235
ACTR1A	02-Medium	0.43	4.69	G2	C1	—	—	B.naive.receptor_recycle (L2)	43	60
ENSG00000293110	02-Medium	0.43	6.02	G1	C2	—	—	—	10	23
ENSG00000309542	02-Medium	0.43	9.61	G1	C2	—	—	—	11	18
ENSG00000309559	02-Medium	0.43	9.61	G1	C2	—	—	—	11	18
ENSG00000267284	02-Medium	0.43	10.75	G2	C1	—	—	—	0	0
ENSG00000299872	02-Medium	0.42	9.30	G1	C2	—	—	—	6	13
IGF2BP1	02-Medium	0.42	9.30	G1	C2	—	induced_pluripotent_stem_cell (Tier: relevant) IPSC.induced_pluripotent_stem_cell (Tier: relevant) IPSC.endoderm_primed (Tier: relevant) IPSC.midbrain_primed (Tier: relevant) IPSC.stress (Tier: relevant)	21 cells — complete matches	6	13
MIR4728	02-Medium	0.42	3.67	G1	C2	—	—	—	26	71
NCKAP5L	02-Medium	0.42	7.62	G1	C2	—	—	17 cells — complete matches	7	13
NFKBIL1	02-Medium	0.42	7.08	G2	C2	—	—	4 cells — complete matches	101	243
DKFZP434A062	02-Medium	0.42	10.21	G1	C2	—	—	—	49	199
PHF13	02-Medium	0.42	7.60	G2	C2	—	—	22 cells — complete matches	5	10
CARD9	02-Medium	0.42	9.18	G1	C2	—	MONO.CD14.remodeling (Tier: specific)	60 cells — complete matches	51	204
ENSG00000286974	02-Medium	0.42	9.74	G1	C2	—	—	—	95	225
CAMK1D	02-Medium	0.42	9.14	G1	C2	—	—	14 cells — complete matches	2	4
MESP2	02-Medium	0.42	9.93	G1	C2	—	—	DC.cDC2.proliferative (L2), EPI.renal_distal_tubule.stress (L2)	9	20
HLA-E	02-Medium	0.42	7.14	G1	C2	EPI.intrahepatic_cholangiocyte_defense.secretory_barrier (L2), EPI.thymic_cortical.baseline (L2), EPI.thymic_medullary.stress_APC (L2), FIB.interstitial.immune_interact (L2), THYMO.SP_CD4_naive (L2)	ADIPO.inflammatory (Tier: relevant)	37 cells — complete matches	193	384
GTF3C2-AS2	02-Medium	0.42	4.61	G2	C1	—	—	—	271	635
ENSG00000288952	02-Medium	0.42	13.16	G1	C2	—	—	—	52	211
ATP5MC1	02-Medium	0.42	6.65	G2	C2	—	—	—	28	75
PDE2A	02-Medium	0.42	4.81	G1	C2	EC.liver_sinusoidal.hypoxia_metabolic (L2), EC.lymphatic.baseline (L2)	—	48 cells — complete matches	5	16
TUBB	02-Medium	0.42	1.16	G1	C2	CHOND.activated_fibro_like (L2), DC.cDC1.proliferative (L2), DC.cDC2.proliferative (L2), EPI.colonic_enteroendocrine.progenitor (L2), EPI.ileal_goblet.immature (L2), OLG.reactive_repair (L2), THYMO.proliferative_S (L2)	—	8 cells — complete matches	165	310
ENSG00000306125	02-Medium	0.42	5.02	G1	C2	—	—	—	14	45
LINC01415	02-Medium	0.42	10.60	G2	C2	—	—	20 cells — complete matches	2	4
IGF2	02-Medium	0.42	16.39	G2	C1	EC.venous.remodeling_stalk (L2), IPSC.mesendo_primed (L2), SMC.metabolic (L2)	GRNLSA.EMT_insulin_signaling (Tier: relevant) HEP.periportal_metabolic.apolipoprotein_secretory (Tier: relevant)	58 cells — complete matches	43	132
TCAP	02-Medium	0.42	4.46	G1	C2	CM.contractile_oxphos (L2)	—	38 cells — complete matches	28	79
ENSG00000299747	02-Medium	0.42	13.50	G1	C2	—	—	—	346	745
ENSG00000232140	02-Medium	0.42	6.50	G1	C2	—	—	—	21	42
BCDIN3D	02-Medium	0.42	7.80	G1	C2	—	HEP.periportal_metabolic.stress_chaperone (Tier: relevant)	10 cells — complete matches	7	13
VWA7	02-Medium	0.42	8.36	G2	C2	—	—	26 cells — complete matches	1	1
TLE1-DT	02-Medium	0.42	9.58	G2	C2	—	—	—	4	5
ENSG00000289021	02-Medium	0.42	6.94	G1	C2	—	—	—	21	62
KRTAP5-6	02-Medium	0.42	8.22	G2	C1	—	—	—	12	43
ENSG00000298922	02-Medium	0.42	9.93	G1	C2	—	—	—	47	119
ENSG00000298944	02-Medium	0.42	9.93	G1	C2	—	—	—	47	119
ENSG00000295395	02-Medium	0.42	10.66	G2	C2	—	—	—	32	106
ENSG00000310496	02-Medium	0.42	6.60	G1	C2	—	—	—	112	169
HLA-K	02-Medium	0.42	6.60	G1	C2	—	—	—	112	169
ENSG00000295266	02-Medium	0.42	9.84	G2	C1	—	—	—	4	7
ENSG00000289921	02-Medium	0.42	9.82	G2	C2	—	—	—	0	0
STARD3	02-Medium	0.41	5.87	G1	C2	—	—	5 cells — complete matches	45	211
ZHX3	02-Medium	0.41	9.17	G1	C2	—	—	16 cells — complete matches	21	43
BCDIN3D-AS1	02-Medium	0.41	6.58	G1	C2	—	—	12 cells — complete matches	7	13
MDC1	02-Medium	0.41	1.14	G1	C2	—	—	10 cells — complete matches	155	295
TMEM59L	02-Medium	0.41	4.51	G2	C2	—	EPI.pancreatic_islet.delta (Tier: relevant)	20 cells — complete matches	16	25
ENSG00000302610	02-Medium	0.41	7.37	G2	C2	—	—	—	4	0
VPS13C	02-Medium	0.41	8.14	G1	C2	—	—	B.naive.proteostasis (L2)	1	2
HLA-G	02-Medium	0.41	5.51	G1	C2	—	MONO.CD14.remodeling (Tier: specific)	33 cells — complete matches	74	109
ENSG00000304559	02-Medium	0.41	12.00	G1	C2	—	—	—	337	717
TTLL6	02-Medium	0.41	6.72	G2	C2	—	EPI.pancreatic_islet.delta (Tier: relevant)	4 cells — complete matches	11	23
PABPC4	02-Medium	0.41	8.99	G1	C2	—	—	4 cells — complete matches	6	19
ENSG00000294669	02-Medium	0.41	6.97	G1	C2	—	—	—	12	19
EMILIN3	02-Medium	0.41	6.93	G2	C2	—	—	8 cells — complete matches	8	18
MIR6871	02-Medium	0.41	8.47	G2	C2	—	—	—	18	41
TRPS1	02-Medium	0.41	12.62	G2	C2	—	—	38 cells — complete matches	2	3
BRD3OS	02-Medium	0.41	8.18	G2	C2	—	—	—	2	3
ZBTB48	02-Medium	0.41	7.24	G1	C2	—	—	B.naive.antigen_presenting_ready (L2), T.CD4_Tcm.crosstalk_myeloid (L2)	5	9
ENSG00000250838	02-Medium	0.41	7.59	G1	C2	—	—	—	11	32
OASL	02-Medium	0.41	7.53	G1	C2	—	HEP.periportal_metabolic.stress_chaperone (Tier: relevant)	88 cells — complete matches	57	132
FBXL20	02-Medium	0.41	7.43	G2	C1	—	—	8 cells — complete matches	3	5
LINC01080	02-Medium	0.41	16.94	G2	C2	—	—	OLG.reactive_repair (L2)	0	0
ENSG00000253389	02-Medium	0.41	13.36	G2	C2	—	—	—	0	0
ENSG00000298961	02-Medium	0.41	10.00	G2	C2	—	—	—	2	7
ENSG00000307923	02-Medium	0.41	12.23	G2	C2	—	—	—	371	796
ENSG00000228302	02-Medium	0.41	9.49	G1	C2	—	—	—	2	4
MIR4686	02-Medium	0.41	12.60	G2	C2	—	—	—	1	0
DNAJC11	02-Medium	0.41	8.14	G2	C2	—	—	8 cells — complete matches	3	8
SYT8	02-Medium	0.41	7.79	G2	C1	EPI.esophageal_basal.activated_progenitor (L2), EPI.extrahepatic_cholangiocyte.mucin_secretory (L2), EPI.hepatic_ductular_cholangiocyte.ion_transport (L2), EPI.pancreatic_ductal_progenitor.biliary_like_xenobiotic (L2), EPI.salivary_intercalated_defense.basal_EMT (L2), EPI.skin_interfollicular_spinous.transition_basal (L2)	—	43 cells — complete matches	21	67
BORCS8	02-Medium	0.41	4.02	G2	C2	—	—	T.CD4_transitional.tissue_enagement (L2)	24	66
LRRC74A	02-Medium	0.41	8.24	G2	C2	—	—	—	4	0
MIR5094	02-Medium	0.40	12.92	G2	C1	—	—	—	0	0
HCG4B	02-Medium	0.40	5.92	G1	C2	—	—	—	11	10
ENSG00000310508	02-Medium	0.40	5.91	G1	C2	—	—	—	14	19
ENSG00000251461	02-Medium	0.40	8.19	G1	C2	—	—	—	5	13
MEF2B	02-Medium	0.40	3.94	G2	C2	B.germinal_center (L1S)	—	5 cells — complete matches	24	66
HLA-DQA2	02-Medium	0.40	8.52	G1	C2	T.CD4_Trm.metal_stress (L2), T.CD4_transitional.APC_interacting (L2)	—	127 cells — complete matches	173	495
MCCD1	02-Medium	0.40	4.03	G1	C2	—	—	—	35	113
ENSG00000310084	02-Medium	0.40	12.23	G2	C2	—	—	—	337	743
APOC1	02-Medium	0.40	7.99	G1	C2	ASPC.adipocyte_capillary_interface (L2), ASPC.remodeling (L2), DC.cDC2.lipid_metabolic (L2), EPI.ectocervical_granular.secretory_apocrine (L2), FIB.reticular.stromal_niche (L2), MAC.MDM.LAM_like (L2), MONO.CD16.hepatic_mac_like (L2)	EPI.pancreatic_ductal_perivascular (Tier: relevant) EPI.pancreatic_ductal_perivascular.baseline (Tier: relevant) GRNLSA.EMT_insulin_signaling (Tier: relevant) GRNLSA.p53_damage (Tier: relevant) HEP.periportal_metabolic.apolipoprotein_secretory (Tier: relevant)	135 cells — complete matches	301	1,434
DDX39B-AS1	02-Medium	0.40	5.14	G2	C2	—	—	12 cells — complete matches	56	182
ENSG00000299760	02-Medium	0.40	5.14	G2	C2	—	—	—	56	182
ANGEL1	02-Medium	0.40	8.60	G1	C2	—	—	16 cells — complete matches	4	0
ENSG00000293820	02-Medium	0.40	5.95	G1	C2	—	—	—	17	37
ENSG00000301233	02-Medium	0.40	9.18	G1	C2	—	—	—	32	72
ENSG00000301220	02-Medium	0.40	10.97	G1	C2	—	—	—	11	35
VPS33B	02-Medium	0.40	8.95	G2	C2	—	—	20 cells — complete matches	18	27
ENSG00000257253	02-Medium	0.40	7.31	G1	C2	—	—	—	4	10
THAP3	02-Medium	0.40	7.64	G2	C2	—	—	5 cells — complete matches	5	9
EIF2S2	02-Medium	0.40	9.30	G1	C2	—	—	—	28	61
FAM99A	02-Medium	0.40	10.05	G2	C1	—	—	—	35	115
HLA-DRB6.2	02-Medium	0.40	11.86	G2	C2	—	—	—	332	742
NT5C1A	02-Medium	0.40	4.12	G1	C2	—	—	NEU.EXC_NTNG1.nuclear_reg (L2)	9	28
KDM2B	02-Medium	0.40	9.11	G2	C2	—	—	32 cells — complete matches	10	31
SNORD14A	02-Medium	0.40	5.34	G1	C2	—	—	—	15	34
SNORD14B	02-Medium	0.40	5.34	G1	C2	—	—	—	15	34
RPS13	02-Medium	0.40	5.34	G1	C2	EC.heart_remodeling.translation_boost (L2), EPI.colonocyte.secretory_boost (L2), EPI.ileal_bile_transport.detox_transcytosis (L2)	EPI.pancreatic_ductal_progenitor (Tier: specific) MONO.CD14.remodeling (Tier: specific) EPI.pancreatic_ductal_perivascular (Tier: relevant) EPI.pancreatic_ductal_perivascular.baseline (Tier: relevant) EPI.pancreatic_ductal_perivascular.protective_antioxidant (Tier: relevant) EPI.pancreatic_ductal_progenitor.baseline (Tier: relevant) EPI.pancreatic_ductal_progenitor.ciliated_transport (Tier: relevant)	97 cells — complete matches	15	34
RALY	02-Medium	0.40	8.75	G2	C2	—	—	—	33	71
SULT4A1	02-Medium	0.40	8.41	G1	C2	—	induced_pluripotent_stem_cell (Tier: relevant) IPSC.induced_pluripotent_stem_cell (Tier: relevant)	7 cells — complete matches	249	495
ENSG00000294466	02-Medium	0.40	9.08	G1	C2	—	—	—	58	138
ENSG00000284946	02-Medium	0.40	8.65	G2	C2	—	—	—	17	26
MICE	02-Medium	0.40	4.42	G1	C2	—	—	—	91	188
NBPF26	02-Medium	0.40	10.65	G1	C2	—	—	17 cells — complete matches	6	8
ENSG00000303124	02-Medium	0.40	6.23	G1	C2	—	—	—	39	94
ZNF654	02-Medium	0.40	5.36	G2	C2	—	—	10 cells — complete matches	0	0
SNORD84	02-Medium	0.40	6.77	G2	C1	—	—	—	59	180
TNNI2	02-Medium	0.40	9.50	G2	C1	SKM.type_1_slow.glycolytic (L2)	—	81 cells — complete matches	29	80
HLA-DRB9	02-Medium	0.40	11.56	G2	C2	—	—	—	337	743
PIK3C2A	02-Medium	0.40	5.22	G2	C1	—	—	8 cells — complete matches	5	6
HEYL	02-Medium	0.40	4.24	G1	C2	EPI.pancreatic_acinar.baseline (L2)	EPI.pancreatic_acinar (Tier: specific) EPI.pancreatic_acinar.adhesion_remodeling (Tier: relevant) IPSC.midbrain_primed (Tier: relevant)	48 cells — complete matches	9	28
ZMIZ1-AS1	02-Medium	0.39	17.68	G2	C2	—	—	25 cells — complete matches	6	18
SNAPC4	02-Medium	0.39	9.28	G1	C2	—	—	29 cells — complete matches	51	203
ENSG00000285693	02-Medium	0.39	4.70	G1	C2	—	—	—	12	20
SRP14	02-Medium	0.39	4.35	G1	C2	EC.arterial.metabolic (L2)	EPI.pancreatic_ductal_progenitor (Tier: specific) EPI.pancreatic_ductal_progenitor.baseline (Tier: relevant) EPI.pancreatic_ductal_progenitor.ciliated_transport (Tier: relevant)	14 cells — complete matches	2	21
JAZF1-AS1	02-Medium	0.39	11.53	G2	C2	—	—	9 cells — complete matches	0	0
CASP3	02-Medium	0.39	7.07	G1	C2	—	—	4 cells — complete matches	6	9
GTF3C2	02-Medium	0.39	4.97	G1	C2	—	—	8 cells — complete matches	280	647
GTF2H4	02-Medium	0.39	3.11	G2	C2	—	—	4 cells — complete matches	61	160
VPS33B-DT	02-Medium	0.39	8.69	G2	C2	—	—	—	0	0
ENSG00000298893	02-Medium	0.39	7.60	G1	C2	—	—	—	3	2
ENSG00000257042	02-Medium	0.39	13.85	G2	C1	—	—	—	2	1
FAIM2	02-Medium	0.39	7.51	G2	C2	—	—	41 cells — complete matches	5	10
ESYT3	02-Medium	0.39	8.04	G2	C2	—	—	7 cells — complete matches	1	1
ENSG00000225903	02-Medium	0.39	5.94	G1	C2	—	—	—	9	28
TRIM26	02-Medium	0.39	3.56	G1	C2	—	—	8 cells — complete matches	69	112
JAZF1	02-Medium	0.39	11.82	G2	C2	—	—	6 cells — complete matches	2	8
ENSG00000306250	02-Medium	0.39	4.49	G1	C2	—	—	—	33	73
KCNK7	02-Medium	0.39	8.66	G2	C2	EPI.skin_keratinocyte_proliferating.early_spinous_transition (L2)	—	47 cells — complete matches	3	6
PARVB	02-Medium	0.39	12.54	G2	C1	PLAT.adhesion (L2)	—	25 cells — complete matches	35	46
MESP1	02-Medium	0.39	10.97	G1	C2	—	—	6 cells — complete matches	8	19
ENSG00000298520	02-Medium	0.39	4.46	G2	C1	—	—	—	267	632
ENSG00000289395	02-Medium	0.39	8.93	G1	C2	—	—	—	2	4
ENSG00000304640	02-Medium	0.39	8.93	G1	C2	—	—	—	2	4
PPM1G	02-Medium	0.39	4.44	G2	C1	—	—	DC.pDC.baseline (L2)	268	632
PNMT	02-Medium	0.39	3.91	G1	C2	—	GRNLSA.EMT_insulin_signaling (Tier: relevant) GRNLSA.p53_damage (Tier: relevant)	29 cells — complete matches	25	75
SNHG32	02-Medium	0.39	10.20	G2	C2	—	—	—	38	69
KCNQ1-AS1	02-Medium	0.39	13.47	G1	C2	—	—	SCHWN.reactive_inflammatory (L2), T.CD8_Tcm.effector_bias (L2)	7	11
GNL1	02-Medium	0.39	5.88	G2	C2	—	—	—	74	175
ENSG00000288473	02-Medium	0.39	2.38	G2	C2	—	—	—	61	160
SLC38A11	02-Medium	0.39	13.75	G2	C1	NEU.EXC_IT.neuromodulated (L2)	EPI.pancreatic_islet.delta (Tier: relevant)	45 cells — complete matches	8	8
ENSG00000231487	02-Medium	0.39	10.32	G2	C1	—	—	—	20	62
ENSG00000290047	02-Medium	0.39	5.16	G2	C2	—	—	—	8	9
VASH1-DT	02-Medium	0.38	4.03	G1	C2	—	—	—	0	0
NOB1	02-Medium	0.38	4.13	G2	C2	—	—	EPI.alveolar_type_1.baseline (L2)	0	0
MIR7107	02-Medium	0.38	5.07	G2	C2	—	—	—	0	0
MANSC4	02-Medium	0.38	13.77	G2	C1	—	—	—	2	2
ENSG00000301691	02-Medium	0.38	15.20	G2	C1	—	—	—	1	4
ENSG00000256747	02-Medium	0.38	13.71	G2	C1	—	—	—	2	2
TNXB	02-Medium	0.38	9.72	G2	C2	GRANU.neutrophil.antiviral_endotoxin (L2)	—	27 cells — complete matches	153	526
ENSG00000306162	02-Medium	0.38	4.01	G1	C2	—	—	—	22	63
ENSG00000295811	02-Medium	0.38	4.78	G1	C2	—	—	—	273	641
KLHL42	02-Medium	0.38	11.82	G2	C1	EPI.pancreatic_islet.beta (L2)	—	16 cells — complete matches	2	2
ENSG00000293757	02-Medium	0.38	3.76	G1	C2	—	—	—	9	28
FNDC4	02-Medium	0.38	5.40	G1	C2	—	adipocyte (Tier: relevant) ADIPO.adipocyte (Tier: relevant) ADIPO.inflammatory (Tier: relevant) GRNLSA.p53_damage (Tier: relevant)	32 cells — complete matches	488	1,610
APOC1P1.2	02-Medium	0.38	5.92	G1	C2	—	—	—	317	1,464
GIP	02-Medium	0.38	7.70	G1	C2	—	—	EPI.colonic_enteroendocrine (L1S), EPI.colonic_enteroendocrine.Lcell_peptide (L2)	18	58
ENSG00000287287	02-Medium	0.38	7.17	G2	C2	—	—	—	6	25
HLA-J	02-Medium	0.38	6.45	G1	C2	—	—	—	54	90
NUP133	02-Medium	0.38	5.14	G2	C2	—	—	8 cells — complete matches	0	5
PRR3	02-Medium	0.38	5.15	G2	C1	—	—	8 cells — complete matches	8	9
NUDT5	02-Medium	0.38	12.72	G2	C2	—	—	—	0	0
APOC1P1	02-Medium	0.38	5.92	G1	C2	—	—	—	317	1,464
ENSG00000294199	02-Medium	0.38	14.17	G2	C2	—	—	—	4	16
STARD10	02-Medium	0.38	5.54	G1	C2	EPI.salivary_mucous_acinar.baseline (L2)	—	24 cells — complete matches	12	22
MICA-AS1	02-Medium	0.38	5.26	G2	C2	—	—	—	210	470
GATAD2A	02-Medium	0.38	6.04	G1	C2	—	—	4 cells — complete matches	106	465
ENSG00000259124	02-Medium	0.38	5.12	G1	C2	—	—	—	0	0
ENSG00000293817	02-Medium	0.38	5.88	G1	C2	—	—	—	12	21
ENSG00000287853	02-Medium	0.38	9.30	G1	C2	—	—	—	28	61
ENSG00000308489	02-Medium	0.38	9.13	G1	C2	—	—	—	5	8
ENSG00000308569	02-Medium	0.38	5.28	G1	C2	—	—	—	24	67
ENSG00000304810	02-Medium	0.38	6.91	G1	C2	—	—	—	5	9
LINC02365	02-Medium	0.38	4.73	G1	C2	—	—	6 cells — complete matches	7	8
ENSG00000303489	02-Medium	0.38	6.13	G1	C2	—	—	—	1	1
ATP2A3	02-Medium	0.38	5.89	G1	C2	—	—	76 cells — complete matches	3	3
ENSG00000304769	02-Medium	0.38	5.89	G1	C2	—	—	—	3	3
WWP2	02-Medium	0.38	7.04	G2	C2	—	—	5 cells — complete matches	10	26
ENSG00000294651	02-Medium	0.38	7.17	G1	C2	—	—	—	14	25
HPCAL4	02-Medium	0.38	4.02	G1	C2	GRNLSA.cholesterol_mevalonate (L2)	—	30 cells — complete matches	7	28
TENT5C	02-Medium	0.38	6.25	G1	C2	—	—	—	17	45
TAS1R1	02-Medium	0.37	7.16	G1	C2	—	—	EPI.colonic_tuft (L1S), EPI.colonic_tuft.activated (L2), FIB.perivascular_interface.lipid_shuttle (L2)	5	9
KCNQ1OT1	02-Medium	0.37	10.96	G2	C1	—	EPI.pancreatic_ductal_bicarbonate.renewal_ion_pump (Tier: relevant)	32 cells — complete matches	3	7
ANKFY1	02-Medium	0.37	4.71	G2	C2	—	—	15 cells — complete matches	0	0
ENSG00000288654	02-Medium	0.37	5.44	G2	C2	—	—	—	0	0
NRBP1	02-Medium	0.37	5.04	G2	C2	—	—	T.CD4_cytotoxic.precursor (L2)	295	731
ENTR1	02-Medium	0.37	8.49	G1	C2	—	—	—	61	236
ZZEF1	02-Medium	0.37	5.69	G1	C2	EPI.salivary_serous_acinar.quiescent (L2)	EPI.salivary_serous_acinar.quiescent (Tier: specific) EPI.pancreatic_ductal_progenitor.ciliated_transport (Tier: relevant)	9 cells — complete matches	4	12
TOP1	02-Medium	0.37	10.54	G2	C1	EPI.alveolar_type_2.injury_primed (L2)	—	B.age_associated.migratory (L2), IPSC.mesendo_primed (L2)	0	0
TSEN2	02-Medium	0.37	8.42	G1	C2	—	—	16 cells — complete matches	72	250
CGGBP1	02-Medium	0.37	5.11	G2	C2	—	—	MONO.CD14.platelet_bound (L2)	0	0
ENSG00000307445	02-Medium	0.37	4.23	G1	C2	—	—	—	3	6
ENSG00000308190	02-Medium	0.37	4.42	G2	C1	—	—	—	62	152
ENSG00000297040	02-Medium	0.37	6.88	G2	C2	—	—	—	180	389
SLC25A16	02-Medium	0.37	3.01	G2	C2	—	—	B.naive.purinergic (L2), T.CD4_cytotoxic.NK_adapted (L2)	10	11
AP2M1	02-Medium	0.37	4.64	G2	C2	—	—	EC.venous.remodeling_stalk (L2)	1	1
SNORD48	02-Medium	0.37	10.25	G2	C2	—	—	—	1	6
ZNF710	02-Medium	0.37	7.74	G1	C2	EPI.pancreatic_acinar.baseline (L2)	EPI.pancreatic_acinar.adhesion_remodeling (Tier: relevant) EPI.pancreatic_acinar.inflammatory_regenerative (Tier: relevant)	25 cells — complete matches	8	20
MICA	02-Medium	0.37	3.30	G2	C2	—	—	7 cells — complete matches	277	593
ENSG00000225913	02-Medium	0.37	5.49	G2	C2	—	—	—	8	20
NUP133-DT	02-Medium	0.37	4.58	G2	C2	—	—	—	0	0
TRIM10	02-Medium	0.36	3.96	G1	C2	—	—	—	122	254
ENSG00000301146	02-Medium	0.36	5.81	G2	C2	—	—	—	6	7
MPV17	02-Medium	0.36	5.08	G1	C2	—	—	EPI.alveolar_type_1.baseline (L2), T.CD4_naive.gut_prone (L2)	274	641
PDE2A-AS1	02-Medium	0.36	3.43	G1	C2	—	—	—	3	10
PLCG1-AS1	02-Medium	0.36	9.13	G2	C2	—	—	12 cells — complete matches	19	41
IFT172	02-Medium	0.36	5.50	G1	C2	—	—	16 cells — complete matches	575	1,693
KCNQ1	02-Medium	0.36	15.70	G1	C2	—	—	40 cells — complete matches	19	294
ENSG00000306205	02-Medium	0.36	7.64	G1	C2	—	—	—	9	20
C2CD4B	02-Medium	0.36	9.19	G1	C2	EPI.pancreatic_acinar.baseline (L2), EPI.pancreatic_acinar.metabolic_onecarbon (L2)	EPI.pancreatic_acinar (Tier: specific) EPI.pancreatic_acinar.adhesion_remodeling (Tier: relevant)	50 cells — complete matches	8	10
ENSG00000286437	02-Medium	0.36	3.41	G1	C2	—	—	—	0	0
BAG6	02-Medium	0.36	8.26	G2	C2	—	—	MONO.CD16.inflammatory (L2)	73	116
CALCOCO2	02-Medium	0.36	5.40	G1	C2	—	—	—	14	25
ENSG00000306597	02-Medium	0.36	4.26	G1	C2	—	—	—	0	0
TENT5C-DT	02-Medium	0.36	6.83	G1	C2	—	—	—	17	43
HLA-F	02-Medium	0.36	3.86	G2	C2	EPI.skin_appendage_keratinocyte.ductal_immune_interacting (L2)	HEP.periportal_metabolic.apolipoprotein_secretory (Tier: relevant)	11 cells — complete matches	205	352
ENSG00000288587	02-Medium	0.36	3.38	G2	C2	—	—	—	257	555
ENSG00000295833	02-Medium	0.36	5.23	G1	C2	—	—	—	274	641
MED22	02-Medium	0.36	1.40	G2	C2	—	MONO.CD14.remodeling (Tier: specific)	22 cells — complete matches	29	42
ENSG00000308375	02-Medium	0.36	10.97	G2	C1	—	—	—	0	0
PPIEL	02-Medium	0.36	8.96	G2	C1	—	—	—	0	0
ABCF1	02-Medium	0.36	5.42	G2	C2	—	—	—	37	84
SLC22A18	02-Medium	0.36	9.42	G1	C2	—	—	9 cells — complete matches	34	86
MAU2	02-Medium	0.36	6.92	G2	C2	—	EPI.pancreatic_ductal_progenitor.ciliated_transport (Tier: relevant)	21 cells — complete matches	61	221
ABCB10	02-Medium	0.36	4.24	G1	C2	—	—	21 cells — complete matches	30	95
CCDC187	02-Medium	0.36	6.84	G1	C2	—	—	—	4	6
PRIMPOL	02-Medium	0.36	3.81	G1	C2	—	—	12 cells — complete matches	7	8
SFXN2	02-Medium	0.36	7.59	G2	C2	—	—	25 cells — complete matches	11	29
ADCY5	02-Medium	0.36	4.39	G1	C2	EPI.colonocyte.ionocyte_BEST4 (L2)	adipocyte (Tier: relevant) ADIPO.adipocyte (Tier: relevant) ADIPO.hypoxia_remodelling (Tier: relevant) ADIPO.inflammatory (Tier: relevant)	24 cells — complete matches	1	1
ENSG00000290870	02-Medium	0.36	6.34	G2	C2	—	—	—	4	4
SENP2	02-Medium	0.36	4.19	G2	C1	PERI.baseline (L2)	—	7 cells — complete matches	6	12
ZDHHC20P1	02-Medium	0.36	4.84	G2	C2	—	—	—	140	226
ENSG00000273750	02-Medium	0.36	7.59	G1	C2	—	—	—	6	15
ENSG00000277542	02-Medium	0.36	7.59	G1	C2	—	—	—	6	15
PRAC2	02-Medium	0.36	7.59	G1	C2	—	—	10 cells — complete matches	6	15
ENSG00000296362	02-Medium	0.36	7.57	G1	C2	—	—	—	28	61
RPL7A	02-Medium	0.35	1.52	G1	C2	—	EPI.pancreatic_ductal_progenitor.baseline (Tier: relevant) EPI.pancreatic_ductal_progenitor.ciliated_transport (Tier: relevant)	40 cells — complete matches	107	152
SNORD24	02-Medium	0.35	1.52	G1	C2	—	—	—	106	151
NOL9	02-Medium	0.35	8.45	G2	C2	—	—	5 cells — complete matches	4	8
ENSG00000306819	02-Medium	0.35	12.96	G2	C2	—	—	—	0	0
TMBIM6	02-Medium	0.35	3.81	G1	C2	EPI.alveolar_type_2.baseline_surfactant (L2), EPI.intrahepatic_cholangiocyte_defense.secretory_barrier (L2)	EPI.pancreatic_ductal_perivascular.protective_antioxidant (Tier: relevant)	6 cells — complete matches	9	15
ENSG00000289720	02-Medium	0.35	4.59	G2	C2	—	—	—	0	0
ENSG00000255750	02-Medium	0.35	8.42	G2	C2	—	—	—	4	4
ITCH	02-Medium	0.35	4.55	G2	C2	—	—	4 cells — complete matches	0	0
MFSD13A	02-Medium	0.35	3.99	G2	C1	—	—	25 cells — complete matches	36	44
FAUP4.2	02-Medium	0.35	5.86	G2	C2	—	—	—	4	4
FCHSD2	02-Medium	0.35	2.62	G1	C2	—	EPI.salivary_serous_acinar.seromucous_like (Tier: relevant)	28 cells — complete matches	6	10
ENSG00000259584	02-Medium	0.35	7.67	G2	C2	—	—	—	2	7
ENSG00000293068	02-Medium	0.35	8.44	G2	C1	—	—	—	5	13
AGER	02-Medium	0.35	4.57	G2	C2	EPI.alveolar_type_1 (L1S), EPI.alveolar_type_1.baseline (L2)	MONO.CD14.remodeling (Tier: specific)	39 cells — complete matches	164	276
FAUP4	02-Medium	0.35	5.70	G2	C2	—	—	—	4	4
TRIM54	02-Medium	0.35	4.82	G1	C2	—	—	22 cells — complete matches	243	450
SUFU	02-Medium	0.35	4.83	G2	C2	—	—	21 cells — complete matches	43	60
NCR3LG1	02-Medium	0.35	12.04	G2	C2	—	—	24 cells — complete matches	5	3
LINC01975	02-Medium	0.35	4.50	G1	C2	—	—	—	2	2
FTO	02-Medium	0.35	14.96	G2	C2	—	—	6 cells — complete matches	7	19
HLA-V.2	02-Medium	0.35	5.66	G1	C2	—	—	—	18	22
ENSG00000306717	02-Medium	0.35	5.28	G1	C2	—	—	—	394	1,491
ZNF710-AS1	02-Medium	0.35	7.69	G1	C2	—	—	7 cells — complete matches	4	13
RFXANK	02-Medium	0.35	3.97	G2	C2	—	—	4 cells — complete matches	24	66
SPATA31H1	02-Medium	0.35	6.38	G1	C2	—	—	—	499	1,593
PPIE	02-Medium	0.35	3.28	G1	C2	—	—	B.naive.proteostasis (L2)	4	13
FAIM	02-Medium	0.35	2.77	G2	C2	—	—	15 cells — complete matches	2	2
ENSG00000266469	02-Medium	0.35	7.21	G2	C2	—	—	—	2	2
ENSG00000307271	02-Medium	0.35	2.72	G1	C2	—	—	—	0	0
ENSG00000294647	02-Medium	0.35	6.05	G2	C2	—	—	—	99	437
ENSG00000290061	02-Medium	0.35	5.76	G2	C2	—	—	—	0	0
LST1	02-Medium	0.35	7.72	G2	C2	granulocyte (L1), macrophage (L1), monocyte (L1), MAC.MDM (L1S), MONO.CD16 (L1S), ILC2.activated (L2), MAC.MDM.inflammatory_phagocytic (L2), MONO.CD14.baseline (L2)	MONO.CD14.remodeling (Tier: specific) MONO.CD14.cord_tolerance (Tier: relevant)	106 cells — complete matches	183	440
ENSG00000288586	02-Medium	0.35	3.80	G1	C2	—	—	—	17	49
ENSG00000298945	02-Medium	0.35	3.14	G1	C2	—	—	—	11	19
NR2C2AP	02-Medium	0.35	4.32	G2	C2	—	—	9 cells — complete matches	26	87
ENSG00000236154	02-Medium	0.34	5.58	G2	C2	—	—	—	0	0
ENSG00000293195	02-Medium	0.34	9.30	G2	C1	—	—	—	0	0
LINC01219	02-Medium	0.34	9.90	G2	C1	—	—	—	42	128
PFDN1P1	02-Medium	0.34	7.50	G2	C2	—	—	—	0	0
UCN	02-Medium	0.34	4.97	G1	C2	—	—	ADIPO.immature (L2), FIB.reticular.stress_metallothionein (L2), MAC.LAM.lipid_opsonization (L2)	255	626
BORCS8-MEF2B	02-Medium	0.34	2.73	G2	C2	—	—	T.CD4_transitional.tissue_enagement (L2)	24	66
C5orf67	02-Medium	0.34	16.14	G2	C2	—	MONO.CD14.remodeling (Tier: specific)	7 cells — complete matches	1	3
ENSG00000309350	02-Medium	0.34	11.08	G2	C2	—	—	—	59	152
TRIM15	02-Medium	0.34	4.13	G1	C2	—	—	15 cells — complete matches	127	228
RALY-AS1	02-Medium	0.34	9.30	G1	C2	—	—	—	31	70
GPAT4	02-Medium	0.34	9.08	G2	C2	—	—	EC.arterial.mito_contact (L2), EC.heart_remodeling.remodeling_stalk (L2), EC.venous.activated (L2)	4	12
ENSG00000214546	02-Medium	0.34	5.73	G1	C2	—	—	—	18	57
ZEB2	02-Medium	0.34	5.13	G2	C2	SCHWN.axon_contact_cardiac (L2), T.CD4_Tem.cytotoxic_effector (L2), T.CD4_Tfh.suppression_exhaustion (L2), T.CD8_Tcm.effector_bias (L2), T.CD8_Tem.baseline (L2), T.CD8_transitional.effector_primed (L2)	GRNLSA.angiocrine_mechanosensory (Tier: relevant)	84 cells — complete matches	3	5
COX20P1	02-Medium	0.34	6.14	G2	C2	—	—	—	0	0
NQO1	02-Medium	0.34	3.87	G2	C2	—	IPSC.endoderm_primed (Tier: relevant)	28 cells — complete matches	2	4
ENSG00000283573	02-Medium	0.34	10.64	G2	C2	—	—	—	30	95
ENSG00000273691	02-Medium	0.34	6.79	G1	C2	—	—	—	5	16
ENSG00000286756	02-Medium	0.34	5.88	G2	C2	—	—	—	1	1
ENSG00000295409	02-Medium	0.34	10.27	G2	C2	—	—	—	0	1
SNORD52	02-Medium	0.34	5.23	G2	C2	—	—	—	32	55
NME9	02-Medium	0.34	10.06	G1	C2	—	—	8 cells — complete matches	1	1
NQO1-DT	02-Medium	0.34	4.10	G2	C2	—	—	—	0	0
ENSG00000223774	02-Medium	0.34	6.25	G2	C2	—	—	—	22	66
SLC30A3	02-Medium	0.34	3.95	G1	C2	—	neuron (Tier: specific)	22 cells — complete matches	223	683
PGAP3	02-Medium	0.34	4.35	G2	C2	—	—	14 cells — complete matches	17	56
ENSG00000299209	02-Medium	0.34	8.88	G2	C1	—	—	—	14	42
ENSG00000225864	02-Medium	0.34	2.76	G2	C2	—	—	—	140	236
ENSG00000305477	02-Medium	0.34	2.53	G1	C2	—	—	—	4	4
ENSG00000236283	02-Medium	0.34	12.26	G2	C1	—	—	—	12	18
PBX4	02-Medium	0.34	6.22	G2	C2	—	—	95 cells — complete matches	51	106
RPL26P19	02-Medium	0.34	14.26	G2	C2	—	—	—	0	0
ENSG00000308322	02-Medium	0.34	2.62	G2	C2	—	—	—	2	5
ARL3	02-Medium	0.34	7.04	G2	C2	—	—	6 cells — complete matches	1	3
MRPS35-DT	02-Medium	0.34	8.13	G2	C2	—	—	—	2	2
ENSG00000307150	02-Medium	0.33	4.47	G2	C2	—	—	—	0	1
ENSG00000278095	02-Medium	0.33	8.16	G2	C2	—	—	—	4	4
SHISA4	02-Medium	0.33	5.37	G2	C2	—	—	23 cells — complete matches	20	62
ENSG00000265460	02-Medium	0.33	9.30	G2	C1	—	—	—	0	0
ENSG00000259362	02-Medium	0.33	12.27	G1	C2	—	—	—	0	1
MIEN1	02-Medium	0.33	3.82	G2	C2	—	—	FIB.perivascular_interface (L1S), EC.lymphatic.valve (L2)	14	49
SFTA2	02-Medium	0.33	2.30	G1	C2	EPI.alveolar_type_1.baseline (L2), EPI.lung_club_secretory.canonical_surfactant (L2)	—	23 cells — complete matches	53	143
NFAT5	02-Medium	0.33	5.18	G2	C1	—	MONO.CD14.cord_tolerance (Tier: relevant)	4 cells — complete matches	6	6
ENSG00000285684	02-Medium	0.33	10.09	G2	C2	—	—	—	0	0
ENSG00000267282	02-Medium	0.33	7.10	G2	C2	—	—	—	213	1,188
ENSG00000259242	02-Medium	0.33	5.90	G2	C2	—	—	—	5	10
ENSG00000296893	02-Medium	0.33	4.62	G2	C2	—	—	—	0	0
TRIM31	02-Medium	0.33	5.06	G2	C2	EPI.colonocyte.distal_absorptive (L2)	EPI.pancreatic_ductal_mucinous.proliferative_gastric_like (Tier: relevant)	30 cells — complete matches	82	107
ENSG00000285545	02-Medium	0.33	10.17	G2	C2	—	—	—	2	1
ENSG00000287183	02-Medium	0.33	1.79	G1	C2	—	—	—	1	2
AIF1	02-Medium	0.33	8.34	G2	C1	IPSC.mesodermal_primed (L2), T.CD4_Tcm.stress (L2)	MONO.CD14.remodeling (Tier: specific) MONO.CD14.cord_tolerance (Tier: relevant)	118 cells — complete matches	433	801
ENSG00000277368	02-Medium	0.33	2.45	G2	C2	—	—	—	0	0
ENSG00000295384	02-Medium	0.33	16.90	G2	C2	—	—	—	30	90
P2RY2	02-Medium	0.33	3.02	G1	C2	—	MONO.CD14.remodeling (Tier: specific)	28 cells — complete matches	7	12
IDH2	02-Medium	0.33	6.18	G1	C2	—	—	7 cells — complete matches	6	17
NEUROD2	02-Medium	0.33	6.14	G1	C2	—	neuron (Tier: specific)	14 cells — complete matches	2	4
ANAPC5	02-Medium	0.33	7.17	G2	C2	—	—	—	5	13
USH1C	02-Medium	0.33	12.87	G2	C2	—	—	27 cells — complete matches	1	1
ENSG00000284196	02-Medium	0.33	13.71	G2	C2	—	—	—	0	0
POLR1H	02-Medium	0.33	3.18	G2	C2	—	—	—	134	224
IGF2BP2-AS1	02-Medium	0.33	17.34	G2	C2	—	—	—	4	7
LTB	02-Medium	0.33	6.05	G2	C1	T.CD4_Tcm (L1S), T.CD4_Tem (L1S), T.CD4_transitional (L1S), T.CD8_Tcm (L1S), T.CD8_transitional (L1S), B.germinal_center.LZ_survival (L2), DC.mig.baseline (L2), HPC.CLP_B_primed (L2), ILC2.activated (L2), T.CD4_Trm.helper_like (L2), T.CD4_cytotoxic.precursor (L2), T.CD8_naive.baseline (L2), T.gamma_delta.central_memory (L2), THYMO.SP_CD8_naive (L2)	EPI.intrahepatic_cholangiocyte_transport.protease_shield_hippo (Tier: relevant)	165 cells — complete matches	127	281
ENSG00000237844	02-Medium	0.33	12.00	G2	C1	—	—	—	1	2
TAP2	02-Medium	0.32	10.34	G2	C2	—	—	10 cells — complete matches	198	364
TNF	02-Medium	0.32	5.40	G2	C1	B.naive.activated (L2), EC.capillary.inflammatory (L2), EPI.ectocervical_granular.inflammatory (L2), EPI.renal_principal_cell.inflammatory (L2), ILC2.activated (L2), MAC.alveolar.inflammatory (L2), MAC.microglia_like.inflammatory_chemokine (L2), T.CD4_Trm.activated (L2), T.CD4_cytotoxic.NK_adapted (L2), T.CD8_Trm.inflammatory (L2)	EPI.intrahepatic_cholangiocyte_transport.protease_shield_hippo (Tier: relevant)	111 cells — complete matches	75	194
DDX39BP2	02-Medium	0.32	6.24	G2	C2	—	—	—	3	2
ENSG00000310512	02-Medium	0.32	6.24	G2	C2	—	—	—	3	2
IGF2BP2	02-Medium	0.32	15.51	G2	C2	EPI.pancreatic_ductal_bicarbonate.repair_actin_junction (L2)	EPI.salivary_serous_acinar.quiescent (Tier: specific) EPI.pancreatic_acinar.inflammatory_regenerative (Tier: relevant)	29 cells — complete matches	6	11
STAC2	02-Medium	0.32	9.30	G2	C1	—	—	15 cells — complete matches	0	0
ANKH	02-Medium	0.32	3.23	G2	C2	MAC.kupffer.tolerogenic (L2)	—	26 cells — complete matches	5	10
QSOX2	02-Medium	0.32	3.72	G1	C2	—	—	23 cells — complete matches	1	1
ITPR2-AS1	02-Medium	0.32	8.54	G2	C2	—	—	—	6	7
ENSG00000306378	02-Medium	0.32	2.98	G2	C2	—	—	—	76	375
LINC02436	02-Medium	0.32	2.07	G1	C2	—	—	—	4	5
C10orf95	02-Medium	0.32	4.07	G2	C1	—	—	14 cells — complete matches	35	43
ENSG00000260772	02-Medium	0.32	3.47	G2	C1	—	—	—	0	0
ENSG00000260588	02-Medium	0.32	8.81	G2	C2	—	—	—	0	0
MAN2A2	02-Medium	0.32	4.96	G2	C2	—	—	18 cells — complete matches	20	34
KCNQ1DN	02-Medium	0.32	15.52	G2	C1	—	—	—	5	8
ENSG00000306443	02-Medium	0.32	12.60	G2	C1	—	—	—	1	1
RNF6	02-Medium	0.32	2.63	G2	C2	—	—	7 cells — complete matches	0	0
OXCT2P1	02-Medium	0.32	4.98	G2	C2	—	—	—	0	0
ENSG00000307950	02-Medium	0.32	11.72	G1	C2	—	—	—	11	18
C10orf95-AS1	02-Medium	0.32	3.79	G2	C1	—	—	—	37	44
ENSG00000287555	02-Medium	0.32	3.88	G2	C2	—	—	—	0	0
ENSG00000288805	02-Medium	0.32	7.63	G2	C2	—	—	—	32	64
CYB5D2	02-Medium	0.32	3.98	G2	C2	—	—	4 cells — complete matches	3	9
ENSG00000250264	02-Medium	0.32	9.46	G2	C2	—	—	—	198	364
GPAT4-AS1	02-Medium	0.32	7.67	G2	C2	—	—	—	1	5
ENSG00000308241	02-Medium	0.31	1.64	G1	C2	—	—	—	7	13
CHD6	02-Medium	0.31	3.48	G2	C2	—	—	FIB.barrier_purinergic.lipid_secretory (L2)	2	2
LTA	02-Medium	0.31	5.40	G2	C1	—	—	105 cells — complete matches	226	418
LINC00243	02-Medium	0.31	3.40	G1	C2	—	—	78 cells — complete matches	192	416
SSPN	02-Medium	0.31	8.12	G2	C2	—	EPI.pancreatic_ductal_perivascular.protective_antioxidant (Tier: relevant)	63 cells — complete matches	10	13
ENSG00000289406	02-Medium	0.31	5.48	G2	C1	—	—	—	201	390
ATF6B	02-Medium	0.31	10.63	G2	C2	—	—	B.age_associated.naive_transitional (L2), EC.lymphatic.valve (L2)	71	164
ENSG00000304294	02-Medium	0.31	4.91	G1	C2	—	—	—	15	34
CDK12	02-Medium	0.31	7.37	G1	C2	—	—	5 cells — complete matches	6	9
MNX1	02-Medium	0.31	14.20	G2	C1	—	EPI.pancreatic_ductal_perivascular (Tier: relevant) EPI.pancreatic_islet (Tier: relevant) EPI.pancreatic_ductal_bicarbonate.renewal_ion_pump (Tier: relevant) EPI.pancreatic_ductal_mucinous.proliferative_gastric_like (Tier: relevant) EPI.pancreatic_ductal_perivascular.baseline (Tier: relevant)	24 cells — complete matches	2	2
RBKS	02-Medium	0.31	0.98	G1	C2	FIB.adventitial.activated_remodelling (L2), SMC.activated (L2)	—	49 cells — complete matches	140	286
LINC01460	02-Medium	0.31	2.55	G2	C2	—	—	cardiomyocyte (L1), CM.cardiomyocyte (L1S), EC.capillary.postcap_venule (L2)	15	40
ENSG00000259080	02-Medium	0.31	5.80	G1	C2	—	—	—	409	1,460
ENSG00000298682	02-Medium	0.31	11.56	G2	C1	—	—	—	0	1
BMF	02-Medium	0.31	6.38	G2	C2	—	IPSC.endoderm_primed (Tier: relevant)	30 cells — complete matches	3	12
ENSG00000294779	02-Medium	0.31	11.25	G2	C2	—	—	—	0	1
TESK1	02-Medium	0.31	3.82	G1	C2	—	—	26 cells — complete matches	18	50
ENSG00000293664	02-Medium	0.31	7.79	G2	C2	—	—	—	0	0
ZNF512	02-Medium	0.31	5.58	G1	C2	—	—	16 cells — complete matches	409	1,460
ENSG00000294270	02-Medium	0.31	4.93	G1	C2	—	—	—	20	60
PLEKHG5	02-Medium	0.31	5.53	G2	C2	—	adipocyte (Tier: relevant) ADIPO.adipocyte (Tier: relevant) ADIPO.hypoxia_remodelling (Tier: relevant)	46 cells — complete matches	3	7
ENSG00000297308	02-Medium	0.31	7.48	G2	C2	—	—	—	2	7
GRB7	02-Medium	0.31	3.70	G2	C2	—	EPI.pancreatic_ductal_perivascular (Tier: relevant) EPI.intrahepatic_cholangiocyte_transport.protease_shield_hippo (Tier: relevant) EPI.pancreatic_ductal_perivascular.baseline (Tier: relevant) IPSC.endoderm_primed (Tier: relevant)	27 cells — complete matches	12	43
ST6GAL1	02-Medium	0.31	11.83	G2	C2	EC.liver_sinusoidal.secretory_lipoprotein (L2), EPI.renal_principal_cell.canonical_vasopressin (L2), THYMO.SP_CD4_naive (L2)	EPI.salivary_serous_acinar.seromucous_like (Tier: relevant)	72 cells — complete matches	105	163
TMEM161A	02-Medium	0.31	1.78	G2	C2	—	—	4 cells — complete matches	25	85
COL4A1	02-Medium	0.31	13.31	G2	C2	FIB.perivascular_interface (L1S), ASPC.adipocyte_capillary_interface (L2), EC.arterial.angiogenic_tip (L2), EC.arterial.arteriole_gas_exchange (L2), EPI.extrahepatic_cholangiocyte.barrier_interface (L2), EPI.hepatic_ductular_cholangiocyte.barrier_chemokine (L2), GRANU.MAST.activated_acute (L2), PC.IgA_muocsal.baseline (L2)	adipocyte (Tier: relevant) ADIPO.adipocyte (Tier: relevant) ADIPO.hypoxia_remodelling (Tier: relevant) ADIPO.inflammatory (Tier: relevant) EPI.intrahepatic_cholangiocyte_transport.protease_shield_hippo (Tier: relevant) GRNLSA.angiocrine_mechanosensory (Tier: relevant)	87 cells — complete matches	38	107
NCAN	02-Medium	0.31	3.48	G2	C2	—	—	10 cells — complete matches	23	65
PFN1P11	02-Medium	0.31	4.38	G2	C2	—	—	—	0	0
ENSG00000297511	02-Medium	0.31	11.21	G2	C2	—	—	—	0	0
SLC30A8	02-Medium	0.30	10.55	G2	C2	—	EPI.pancreatic_islet (Tier: relevant) EPI.pancreatic_islet.delta (Tier: relevant)	5 cells — complete matches	0	0
ENSG00000299582	02-Medium	0.30	14.36	G2	C2	—	—	—	5	11
SLC22A18AS	02-Medium	0.30	5.80	G1	C2	—	MONO.CD14.remodeling (Tier: specific)	27 cells — complete matches	9	19
ENSG00000286752	02-Medium	0.30	7.40	G2	C2	—	—	—	3	3
RNF34	02-Medium	0.30	8.20	G2	C2	—	—	B.naive.proteostasis (L2), T.CD8_transitional.stress (L2)	7	12
LINC02736	02-Medium	0.30	5.91	G2	C2	—	—	—	1	1
NOM1	02-Medium	0.30	11.19	G2	C1	—	—	11 cells — complete matches	2	7
BUB1B	02-Medium	0.30	5.45	G2	C2	THYMO.proliferative_G2M (L2)	EPI.pancreatic_ductal_mucinous.proliferative_gastric_like (Tier: relevant) HEP.acute_phase.proliferative (Tier: relevant)	37 cells — complete matches	5	15
RUSC2	02-Medium	0.30	7.45	G2	C2	EPI.pancreatic_ductal_bicarbonate.baseline (L2)	—	22 cells — complete matches	5	21
SURF4	02-Medium	0.30	1.63	G1	C2	—	—	EPI.alveolar_type_1.baseline (L2), ILC2.migratory (L2)	29	41
MOG	02-Medium	0.30	3.05	G2	C2	oligodendrocyte (L1), OLG.oligodendrocyte (L1S)	—	10 cells — complete matches	6	8
DYNLRB1	02-Medium	0.30	4.47	G2	C2	—	—	MAC.resident_iron.stress_tolerogenic (L2), MG.expanding (L2)	0	0
DDR1	02-Medium	0.30	3.20	G2	C2	—	—	10 cells — complete matches	121	263
TSBP1-AS1	02-Medium	0.30	8.00	G2	C2	—	—	—	106	195
TSPAN3	02-Medium	0.30	9.09	G2	C2	EPI.cervical_suprabasal.secretory_vesicle (L2), EPI.intrahepatic_cholangiocyte_defense.secretory_barrier (L2), EPI.salivary_mucous_acinar.baseline (L2)	EPI.pancreatic_ductal_perivascular.protective_antioxidant (Tier: relevant)	8 cells — complete matches	14	27
TBC1D3H	02-Medium	0.30	6.55	G1	C2	—	—	—	11	14
RPL36AP33	02-Medium	0.30	7.68	G2	C2	—	—	—	0	0
ENSG00000302088	02-Medium	0.30	6.12	G2	C2	—	—	—	1	5
ENSG00000308209	02-Medium	0.30	3.36	G2	C2	—	—	—	0	0
ENSG00000299237	02-Medium	0.30	5.77	G2	C2	—	—	—	0	0
ENSG00000299253	02-Medium	0.30	5.77	G2	C2	—	—	—	0	0
ENSG00000259420	02-Medium	0.30	12.18	G2	C2	—	—	—	0	1
ENSG00000306490	02-Medium	0.30	4.66	G2	C2	—	—	—	3	9
MIR4667	02-Medium	0.30	3.91	G1	C2	—	—	—	16	48
SRGAP2C	02-Medium	0.29	7.24	G1	C2	—	EPI.pancreatic_ductal_progenitor.ciliated_transport (Tier: relevant)	36 cells — complete matches	11	28
CNTN2	02-Medium	0.29	7.41	G2	C2	IPSC.midbrain_primed (L2)	IPSC.midbrain_primed (Tier: relevant)	16 cells — complete matches	4	4
ENSG00000284829	02-Medium	0.29	9.93	G2	C2	—	—	—	41	114
MIR7847	02-Medium	0.29	6.12	G2	C1	—	—	—	23	75
CLEC18A	02-Medium	0.29	6.59	G2	C2	—	—	9 cells — complete matches	1	3
ENSG00000300048	02-Medium	0.29	5.65	G2	C2	—	—	—	1	1
CRTC1	02-Medium	0.29	6.30	G2	C2	—	—	21 cells — complete matches	9	22
HCG4P8	02-Medium	0.29	4.82	G2	C2	—	—	—	3	2
PPFIBP1	02-Medium	0.29	4.16	G2	C2	EC.lymphatic.baseline (L2), NEU.EXC_CT.Ca2_signaling (L2)	—	35 cells — complete matches	2	8
G6PC2	02-Medium	0.29	5.73	G2	C2	EPI.pancreatic_islet.beta (L2)	EPI.pancreatic_islet (Tier: relevant) EPI.pancreatic_islet.delta (Tier: relevant)	5 cells — complete matches	11	41
VAV2	02-Medium	0.29	4.97	G2	C2	—	—	24 cells — complete matches	4	5
STKLD1	02-Medium	0.29	1.64	G1	C2	—	—	14 cells — complete matches	29	41
P2RX1	02-Medium	0.29	5.58	G2	C2	—	EPI.pancreatic_acinar (Tier: specific) MONO.CD14.remodeling (Tier: specific)	72 cells — complete matches	29	42
ENSG00000229660	02-Medium	0.29	11.38	G2	C1	—	—	—	0	1
ENSG00000294878	02-Medium	0.29	11.05	G2	C2	—	—	—	0	0
HCG4	02-Medium	0.29	3.98	G2	C2	—	—	—	13	17
ARMC6	02-Medium	0.29	0.76	G2	C2	—	—	11 cells — complete matches	25	85
HLA-V	02-Medium	0.29	3.87	G2	C2	—	—	—	8	13
ENSG00000253174	02-Medium	0.29	5.93	G2	C2	—	—	—	2	6
REXO4	02-Medium	0.29	1.52	G2	C2	—	—	6 cells — complete matches	45	64
CUEDC2	02-Medium	0.29	3.59	G2	C2	—	—	4 cells — complete matches	35	46
PEAK1	02-Medium	0.29	10.38	G2	C2	—	EPI.salivary_serous_acinar.seromucous_like (Tier: relevant)	19 cells — complete matches	0	0
LSP1	02-Medium	0.29	7.71	G2	C1	B.age_associated.migratory (L2), EPI.salivary_myoepithelial.junctional_transport (L2), EPI.skin_follicular_keratinizing.upper_infundibulum (L2), EPI.thymic_medullary.canonical_alarmin (L2), T.CD4_Treg.APC_interactive (L2), T.CD8_Trm.cytotoxic (L2)	MONO.CD14.remodeling (Tier: specific)	102 cells — complete matches	41	132
ENSG00000294014	02-Medium	0.29	6.72	G2	C2	—	—	—	0	0
SUGP1	02-Medium	0.29	6.34	G2	C2	—	—	13 cells — complete matches	57	186
ENSG00000295124	02-Medium	0.29	10.73	G2	C1	—	—	—	0	1
SPDYE10	02-Medium	0.29	10.12	G2	C2	—	—	—	185	1,059
BHLHE41	02-Medium	0.29	6.76	G2	C2	—	—	55 cells — complete matches	16	23
ENSG00000256894	02-Medium	0.29	6.76	G2	C2	—	—	—	16	23
PSD	02-Medium	0.29	3.99	G2	C2	—	—	39 cells — complete matches	35	43
ENSG00000261136	02-Medium	0.28	5.74	G2	C2	—	—	—	8	19
ENSG00000256185	02-Medium	0.28	6.09	G2	C2	—	—	—	4	4
ENSG00000298730	02-Medium	0.28	7.77	G1	C2	—	—	—	5	252
INS	02-Medium	0.28	10.17	G2	C2	—	—	—	36	121
INS-IGF2	02-Medium	0.28	10.17	G2	C2	EPI.pancreatic_ductal_progenitor.ADM_like (L2)	EPI.pancreatic_acinar (Tier: specific) EPI.pancreatic_ductal_progenitor (Tier: specific) EPI.pancreatic_ductal_perivascular (Tier: relevant) EPI.pancreatic_islet (Tier: relevant) EPI.pancreatic_acinar.inflammatory_regenerative (Tier: relevant) EPI.pancreatic_ductal_mucinous.proliferative_gastric_like (Tier: relevant) EPI.pancreatic_ductal_perivascular.baseline (Tier: relevant) EPI.pancreatic_ductal_perivascular.protective_antioxidant (Tier: relevant) EPI.pancreatic_ductal_progenitor.baseline (Tier: relevant) EPI.pancreatic_ductal_progenitor.ciliated_transport (Tier: relevant) EPI.pancreatic_islet.delta (Tier: relevant)	29 cells — complete matches	36	121
ENSG00000309604	02-Medium	0.28	7.94	G2	C1	—	—	—	0	0
FBXL15	02-Medium	0.28	3.48	G2	C2	—	—	26 cells — complete matches	37	45
FSIP1	02-Medium	0.28	5.26	G2	C2	NEU.EXC_SYT2.nuclear_reg (L2)	MONO.CD14.remodeling (Tier: specific)	20 cells — complete matches	7	19
NFKB2	02-Medium	0.28	4.14	G2	C2	EPI.pancreatic_ductal_bicarbonate.inflammatory (L2), FIB.suburothelial.inflammatory_prostanoid (L2), HEP.acute_phase.inflammatory (L2)	—	15 cells — complete matches	46	66
LINC00229	02-Medium	0.28	7.99	G2	C2	—	—	—	1	0
ESPN	02-Medium	0.28	5.23	G2	C2	—	HEP.periportal_metabolic.apolipoprotein_secretory (Tier: relevant)	49 cells — complete matches	0	147
ADAMTS13	02-Medium	0.28	1.80	G2	C2	—	—	20 cells — complete matches	37	50
PHLDA2	02-Medium	0.28	6.23	G1	C2	EPI.esophageal_basal.junctional_barrier (L2), EPI.renal_principal_cell.inflammatory (L2), EPI.renal_thick_ascending_limb.barrier_repair (L2), FIB.interstitial.stress_secretory (L2), MAC.resident_iron.stress_tolerogenic (L2)	IPSC.stress (Tier: relevant) MONO.CD14.cord_tolerance (Tier: relevant)	78 cells — complete matches	6	9
ENSG00000302189	02-Medium	0.28	4.99	G2	C2	—	—	—	3	4
GPR176	02-Medium	0.28	5.53	G2	C2	—	—	44 cells — complete matches	10	21
ENSG00000309803	02-Medium	0.28	3.26	G1	C2	—	—	—	12	32
PAK6	02-Medium	0.28	4.66	G2	C2	—	—	10 cells — complete matches	3	12
MIR146B	02-Medium	0.28	3.60	G2	C2	—	—	—	37	44
DNAJB6	02-Medium	0.28	10.56	G2	C1	EPI.pancreatic_ductal_bicarbonate.stress (L2), NK.adaptive_adipose_stress (L2), T.CD4_cytotoxic.activated (L2)	—	7 cells — complete matches	0	1
HACD2	02-Medium	0.28	2.68	G1	C2	—	—	8 cells — complete matches	6	11
RPL19	02-Medium	0.28	7.83	G2	C1	EC.heart_remodeling.translation_boost (L2), EPI.ileal_enterocyte_absorptive.villus_tip (L2), MG.expanding (L2)	EPI.pancreatic_ductal_progenitor (Tier: specific) MONO.CD14.remodeling (Tier: specific) EPI.pancreatic_ductal_perivascular (Tier: relevant) EPI.pancreatic_ductal_perivascular.baseline (Tier: relevant) EPI.pancreatic_ductal_perivascular.protective_antioxidant (Tier: relevant) EPI.pancreatic_ductal_progenitor.baseline (Tier: relevant) EPI.pancreatic_ductal_progenitor.ciliated_transport (Tier: relevant) HEP.periportal_metabolic.apolipoprotein_secretory (Tier: relevant)	112 cells — complete matches	0	0
PPP1R18	02-Medium	0.28	1.27	G2	C2	—	—	12 cells — complete matches	153	285
PSMB8	02-Medium	0.28	7.30	G2	C2	—	—	5 cells — complete matches	200	385
ENSG00000289326	02-Medium	0.27	2.13	G2	C2	—	—	—	22	54
SLC25A42	02-Medium	0.27	1.21	G2	C2	—	HEP.periportal_metabolic (Tier: specific)	31 cells — complete matches	28	89
LINC02570	02-Medium	0.27	3.37	G1	C2	—	—	—	29	61
ENSG00000279175	02-Medium	0.27	9.35	G2	C2	—	—	—	1	1
ENSG00000299416	02-Medium	0.27	6.78	G2	C2	—	—	—	1	1
GOLGA7	02-Medium	0.27	5.37	G2	C2	—	—	MONO.CD14.platelet_bound (L2), PLAT.adhesion (L2)	1	1
LMOD1	02-Medium	0.27	5.00	G2	C2	—	—	32 cells — complete matches	34	89
CYB5B	02-Medium	0.27	4.25	G2	C2	—	—	—	0	0
TMEM154	02-Medium	0.27	4.46	G2	C2	—	—	52 cells — complete matches	0	0
ENSG00000289259	02-Medium	0.27	5.98	G2	C2	—	—	—	4	4
PAK6-AS1	02-Medium	0.27	4.89	G2	C2	—	—	—	4	13
GBF1	02-Medium	0.27	3.65	G2	C2	—	EPI.salivary_serous_acinar.quiescent (Tier: specific)	EC.heart_remodeling.remodeling_secretory (L2), EPI.salivary_serous_acinar.quiescent (L2)	33	38
ENSG00000298413	02-Medium	0.27	3.81	G2	C2	—	—	—	37	44
GPR176-DT	02-Medium	0.27	4.92	G2	C2	—	—	—	6	17
CLEC18C	02-Medium	0.27	5.46	G2	C2	—	—	6 cells — complete matches	31	62
ENSG00000298312	02-Medium	0.27	9.69	G2	C2	—	—	—	0	0
ENSG00000290957	02-Medium	0.27	3.03	G2	C1	—	—	—	6	14
ENSG00000288837	02-Medium	0.27	1.01	G2	C2	—	—	—	5	30
ENSG00000293879	02-Medium	0.27	3.25	G1	C2	—	—	—	152	319
ELOVL3	02-Medium	0.27	2.83	G2	C2	—	—	13 cells — complete matches	32	43
NEAT1	02-Medium	0.27	5.46	G2	C2	EC.lymphatic.scavenger (L2), EPI.alveolar_type_1.activated (L2), EPI.colonic_tuft.activated (L2), FIB.lung_alveolar.stress_interacting (L2), MEL.dedifferentiated_migratory (L2), NEU.INH_PVALB.neuromodulatory (L2), PC.IgA_muocsal.migratory (L2), PERI.baseline (L2)	HEP.acute_phase (Tier: specific) EPI.salivary_serous_acinar.quiescent (Tier: specific) HEP.periportal_metabolic.inflammatory_activated (Tier: specific) HEP.periportal_metabolic.urea_onecarbon_secretory (Tier: specific) ADIPO.hypoxia_remodelling (Tier: relevant) ADIPO.inflammatory (Tier: relevant) EPI.pancreatic_acinar.adhesion_remodeling (Tier: relevant) EPI.pancreatic_acinar.inflammatory_regenerative (Tier: relevant) EPI.salivary_serous_acinar.seromucous_like (Tier: relevant) GRNLSA.angiocrine_mechanosensory (Tier: relevant) HEP.acute_phase.proliferative (Tier: relevant) MONO.CD14.cord_tolerance (Tier: relevant)	92 cells — complete matches	23	70
ENSG00000301134	02-Medium	0.27	7.75	G2	C2	—	—	—	37	81
IKZF3	02-Medium	0.27	1.44	G1	C2	—	—	89 cells — complete matches	83	204
SLC44A4	02-Medium	0.27	3.79	G2	C2	EPI.hepatic_ductular_cholangiocyte.ion_transport (L2), EPI.intrahepatic_cholangiocyte_transport.mucin_secretory (L2), EPI.pancreatic_ductal_bicarbonate.barrier_mucin (L2)	EPI.pancreatic_ductal_mucinous.proliferative_gastric_like (Tier: relevant) EPI.salivary_serous_acinar.seromucous_like (Tier: relevant)	46 cells — complete matches	23	31
NEU1	02-Medium	0.27	3.73	G2	C2	—	EPI.pancreatic_ductal_perivascular.protective_antioxidant (Tier: relevant)	7 cells — complete matches	26	37
REP15	02-Medium	0.26	5.72	G2	C2	EPI.colonocyte.goblet_interface (L2), EPI.ileal_enterocyte_crypt.secretory_precursor (L2), EPI.ileal_goblet.baseline (L2)	—	17 cells — complete matches	0	0
ENSG00000294041	02-Medium	0.26	7.97	G2	C2	—	—	—	30	95
ENSG00000304754	02-Medium	0.26	8.07	G2	C2	—	—	—	28	98
PLEKHA7	02-Medium	0.26	2.57	G2	C1	—	EPI.salivary_serous_acinar.quiescent (Tier: specific) adipocyte (Tier: relevant) ADIPO.adipocyte (Tier: relevant) ADIPO.hypoxia_remodelling (Tier: relevant)	31 cells — complete matches	8	19
PSMB9	02-Medium	0.26	7.21	G2	C2	—	—	21 cells — complete matches	227	422
MIR4453	02-Medium	0.26	5.36	G2	C2	—	—	—	0	0
MIR4453HG	02-Medium	0.26	5.36	G2	C2	—	—	—	0	0
ENSG00000294852	02-Medium	0.26	12.86	G2	C2	—	—	—	0	0
PSMB8-AS1	02-Medium	0.26	7.06	G2	C2	—	—	10 cells — complete matches	204	380
ENSG00000308011	02-Medium	0.26	4.26	G2	C2	—	—	—	31	89
ENSG00000297548	02-Medium	0.26	14.75	G2	C2	—	—	—	0	2
TIMM17A	02-Medium	0.26	5.13	G2	C2	—	—	—	21	49
SURF2	02-Medium	0.26	1.49	G1	C2	—	—	—	35	74
TAP1	02-Medium	0.26	7.21	G2	C2	EPI.thymic_cortical.baseline (L2)	—	ASPC.inflammatory (L2), GRANU.neutrophil.antiviral_endotoxin (L2), HEP.periportal_metabolic.acute_phase_barrier (L2)	201	382
ENSG00000287535	02-Medium	0.26	4.72	G2	C2	—	—	—	1	0
SURF1	02-Medium	0.26	1.37	G1	C2	—	—	T.CD4_Tcm.APC_mimicry (L2)	27	40
KRTAP5-5	02-Medium	0.26	5.93	G2	C2	—	—	—	5	7
SYTL2	02-Medium	0.26	2.32	G2	C2	EPI.colonocyte.proximal_transport (L2), EPI.gastric_foveolar.baseline (L2), THYMO.SP_CD4_naive (L2)	GRNLSA.angiocrine_mechanosensory (Tier: relevant)	91 cells — complete matches	2	3
ENSG00000293897	02-Medium	0.26	3.38	G1	C2	—	—	—	122	272
ANKRD63	02-Medium	0.26	3.56	G2	C2	—	—	—	4	13
ZFP57	02-Medium	0.25	3.37	G2	C2	—	—	34 cells — complete matches	59	109
ENEMAL	02-Medium	0.25	5.81	G2	C2	—	—	—	3	3
ENSG00000296257	02-Medium	0.25	4.86	G2	C2	—	—	—	3	3
ENSG00000305455	02-Medium	0.25	6.01	G2	C2	—	—	—	3	9
LPAR2	02-Medium	0.25	5.58	G2	C2	—	—	74 cells — complete matches	15	30
ENSG00000309629	02-Medium	0.25	5.69	G2	C2	—	—	—	25	47
TERF2	02-Medium	0.25	2.92	G2	C2	—	—	21 cells — complete matches	0	0
ENSG00000276261	02-Medium	0.25	5.97	G2	C2	—	—	—	0	0
BMAL2-AS1	02-Medium	0.25	1.93	G2	C2	—	—	—	2	8
ENSG00000223761	02-Medium	0.25	6.07	G2	C1	—	—	—	7	18
LIFR	02-Medium	0.25	5.66	G2	C2	EC.liver_sinusoidal.secretory_lipoprotein (L2), HEP.canalicular_transport.sterol_lipid_biosynthesis (L2)	GRNLSA.angiocrine_mechanosensory (Tier: relevant)	38 cells — complete matches	0	1
PPP1R10	02-Medium	0.25	2.88	G2	C2	HPC.MPP_activated (L2), MEL.dedifferentiated_migratory (L2)	—	4 cells — complete matches	68	161
MRPS35	02-Medium	0.25	8.27	G2	C1	—	—	EC.arterial.ion_pump (L2)	2	2
ENSG00000295134	02-Medium	0.25	5.86	G2	C2	—	—	—	0	0
SNORD36A	02-Medium	0.25	1.52	G1	C2	—	—	—	28	41
SNORD36B	02-Medium	0.25	1.52	G1	C2	—	—	—	28	41
SNORD36C	02-Medium	0.25	1.52	G1	C2	—	—	—	28	41
WDR5	02-Medium	0.25	3.12	G2	C2	—	—	8 cells — complete matches	3	7
PSTPIP1	02-Medium	0.25	6.56	G2	C2	—	—	85 cells — complete matches	6	6
PARVG	02-Medium	0.25	7.83	G2	C2	—	—	42 cells — complete matches	2	1
RNPEP	02-Medium	0.25	4.73	G2	C2	—	—	MONO.CD16.inflammatory (L2)	15	36
MNX1-AS1	02-Medium	0.25	12.33	G2	C2	—	EPI.pancreatic_ductal_progenitor (Tier: specific) EPI.pancreatic_ductal_progenitor.baseline (Tier: relevant) EPI.pancreatic_ductal_progenitor.ciliated_transport (Tier: relevant)	11 cells — complete matches	2	2
WDR5-DT	02-Medium	0.25	3.47	G2	C2	—	—	—	2	4
CIMIP2B	02-Medium	0.25	6.64	G2	C2	—	—	—	7	17
ENSG00000296261	02-Medium	0.24	4.36	G2	C2	—	—	—	0	0
ENSG00000287422	02-Medium	0.24	9.75	G2	C2	—	—	—	1	6
SFRP1	02-Medium	0.24	5.07	G2	C2	EPI.renal_thick_ascending_limb.salt_sensing (L2), FIB.interstitial.remodeling (L2), IPSC.mesenchymal_primed (L2)	—	77 cells — complete matches	2	12
UPF1	02-Medium	0.24	5.31	G2	C2	—	—	19 cells — complete matches	33	54
ENSG00000293908	02-Medium	0.24	6.52	G2	C2	—	—	—	8	56
ENSG00000301820	02-Medium	0.24	2.79	G2	C2	—	—	—	16	17
IPO9-AS1	02-Medium	0.24	6.11	G2	C2	—	—	18 cells — complete matches	1	2
SURF6	02-Medium	0.24	1.27	G1	C2	—	—	7 cells — complete matches	27	40
IPO9	02-Medium	0.24	5.42	G2	C2	—	—	13 cells — complete matches	9	31
ENSG00000305844	02-Medium	0.24	4.30	G2	C2	—	—	—	10	12
PLCB2	02-Medium	0.24	2.93	G2	C2	—	MONO.CD14.remodeling (Tier: specific)	57 cells — complete matches	4	13
RASSF8	02-Medium	0.24	3.21	G2	C2	—	—	29 cells — complete matches	18	26
ENSG00000305854	02-Medium	0.23	3.90	G2	C2	—	—	—	5	11
INAFM2	02-Medium	0.23	3.06	G2	C2	—	—	32 cells — complete matches	8	20
ENSG00000297454	02-Medium	0.23	7.72	G2	C2	—	—	—	44	174
CACFD1	02-Medium	0.23	1.85	G1	C2	—	—	12 cells — complete matches	52	72
NOLC1	02-Medium	0.23	2.59	G2	C2	—	—	EC.liver_sinusoidal.prostanoid (L2), EC.venous.remodeling_stalk (L2)	5	4
ENSG00000306860	02-Medium	0.23	8.15	G2	C2	—	—	—	0	0
ENSG00000280434	02-Medium	0.23	6.74	G2	C2	—	—	—	1	1
ENSG00000231102	02-Medium	0.23	5.14	G2	C2	—	—	—	5	15
ENSG00000310399	02-Medium	0.23	3.57	G2	C2	—	—	—	2	6
ENSG00000279537	02-Medium	0.23	3.90	G2	C2	—	—	—	0	2
ENSG00000286970	02-Medium	0.23	3.09	G2	C2	—	—	—	4	8
ENSG00000295415	02-Medium	0.23	10.32	G2	C2	—	—	—	0	0
CCDC9B	02-Medium	0.23	3.19	G2	C2	—	—	—	6	16
SPPL3	02-Medium	0.23	4.03	G2	C2	—	—	T.CD4_Treg.Tr1_like (L2), T.CD4_transitional.tissue_enagement (L2)	22	53
ENSG00000299210	02-Medium	0.23	8.32	G2	C2	—	—	—	0	0
SMCO2	02-Medium	0.23	1.48	G2	C2	—	—	NEU.EXC_IT.neuromodulated (L2), NEU.EXC_IT.transitional (L2)	2	8
CYP17A1	02-Medium	0.23	7.06	G2	C2	EPI.renal_proximal_tubule.onecarbon_peroxisome (L2), EPI.skin_sweat_duct_keratinocyte.suprabasal_hypoxic (L2)	—	11 cells — complete matches	22	50
ENSG00000298230	02-Medium	0.23	4.68	G2	C2	—	—	—	0	0
TET1	02-Medium	0.22	3.99	G2	C1	—	EPI.salivary_serous_acinar.quiescent (Tier: specific) EPI.salivary_serous_acinar.seromucous_like (Tier: relevant)	18 cells — complete matches	1	1
ENSG00000299548	02-Medium	0.22	8.03	G2	C2	—	—	—	0	1
ENSG00000274093	02-Medium	0.22	4.43	G2	C1	—	—	—	1	0
NAV1	02-Medium	0.22	6.33	G2	C2	—	—	38 cells — complete matches	12	34
TCF4-AS1	02-Medium	0.22	9.56	G2	C2	—	—	4 cells — complete matches	0	0
ENSG00000290057	02-Medium	0.22	3.63	G2	C2	—	—	—	8	18
PGC	02-Medium	0.22	5.53	G2	C2	EPI.pancreatic_ductal_mucinous.proliferative_gastric_like (L2)	EPI.pancreatic_ductal_mucinous.proliferative_gastric_like (Tier: relevant)	17 cells — complete matches	26	125
CAMTA1	02-Medium	0.22	0.85	G2	C2	—	—	GRANU.MAST (L1S)	14	39
ENSG00000247228	02-Medium	0.22	3.35	G2	C2	—	—	—	1	1
ENSG00000286493	02-Medium	0.22	4.12	G2	C2	—	—	—	24	56
SLC2A6	02-Medium	0.22	1.71	G1	C2	—	—	28 cells — complete matches	48	58
IVD	02-Medium	0.22	2.17	G2	C2	—	—	EPI.skin_interfollicular_spinous.inflammatory (L2), MAC.resident_iron.heme_recycling (L2), T.CD4_Th2.precursor (L2)	4	13
FAM245A	02-Medium	0.22	4.25	G2	C1	—	—	—	9	20
ACADS	02-Medium	0.21	3.61	G2	C2	—	—	5 cells — complete matches	21	53
ENSG00000295387	02-Medium	0.21	9.09	G2	C2	—	—	—	1	1
TNNT3	02-Medium	0.21	5.30	G2	C2	SKM.type_2_fast (L1S), SKM.type_1_slow.glycolytic (L2)	—	52 cells — complete matches	24	72
PRR5	02-Medium	0.21	5.57	G2	C2	T.CD4_Trm.helper_like (L2)	—	47 cells — complete matches	2	1
ENSG00000259269	02-Medium	0.21	4.74	G2	C2	—	—	—	8	16
NUTM2A-AS1	02-Medium	0.21	2.46	G2	C1	—	—	HEP.pericentral_lipoprotein.UPR_redox (L2)	12	23
ENSG00000230834	02-Medium	0.21	2.29	G2	C1	—	—	—	6	10
DISP2	02-Medium	0.20	2.28	G2	C2	—	—	8 cells — complete matches	4	13
TAF5L	02-Medium	0.20	2.86	G2	C2	—	—	21 cells — complete matches	36	107
LINC01378	02-Medium	0.20	1.76	G2	C2	—	neuron (Tier: specific)	6 cells — complete matches	0	0
KNSTRN	02-Medium	0.20	2.06	G2	C2	B.germinal_center.DZ_M_phase (L2)	MONO.CD14.remodeling (Tier: specific)	23 cells — complete matches	4	14
ENSG00000296223	02-Medium	0.20	4.11	G2	C1	—	—	—	2	3
UNC119B	02-Medium	0.20	2.81	G2	C2	—	—	21 cells — complete matches	17	29
P2RX7	02-Medium	0.20	3.92	G2	C2	—	HEP.periportal_metabolic (Tier: specific) MONO.CD14.remodeling (Tier: specific)	42 cells — complete matches	6	9
ENSG00000296418	02-Medium	0.20	4.60	G2	C2	—	—	—	1	1
LINC01512	02-Medium	0.19	4.12	G2	C2	—	—	—	30	95
IFITM10	02-Medium	0.19	2.95	G2	C2	EC.liver_sinusoidal.secretory_lipoprotein (L2)	—	63 cells — complete matches	3	8
POP5	02-Medium	0.19	2.05	G2	C2	—	—	—	19	32
SARDH	02-Medium	0.19	2.71	G2	C2	—	—	36 cells — complete matches	18	28
ENSG00000289876	02-Medium	0.18	4.74	G2	C2	—	—	—	0	0
MRPL33	02-Medium	0.18	1.48	G2	C2	—	—	—	20	53
ARL5C	02-Medium	0.18	6.11	G2	C2	—	EPI.pancreatic_acinar (Tier: specific)	13 cells — complete matches	0	0
CREBZF	02-Medium	0.18	2.54	G2	C2	EC.venous.cardiac_structural (L2), PERI.baseline (L2)	—	8 cells — complete matches	2	3
MDFI	02-Medium	0.18	3.61	G2	C2	—	adipocyte (Tier: relevant) ADIPO.adipocyte (Tier: relevant) ADIPO.hypoxia_remodelling (Tier: relevant) IPSC.endoderm_primed (Tier: relevant)	54 cells — complete matches	13	54
URB2	02-Medium	0.18	2.72	G2	C2	—	—	23 cells — complete matches	36	107
ENSG00000295288	02-Medium	0.18	1.97	G2	C2	—	—	—	1	1
CCDC89	02-Medium	0.17	2.74	G2	C2	—	—	15 cells — complete matches	2	1
SCIRT	02-Medium	0.17	3.56	G2	C2	—	—	—	36	110
ENSG00000260400	02-Medium	0.17	2.79	G2	C1	—	—	—	1	1
ENSG00000293949	02-Medium	0.17	5.35	G2	C2	—	—	—	31	96
MIR3650	02-Medium	0.17	5.54	G2	C2	—	—	—	0	1
ENSG00000279742	02-Medium	0.16	1.71	G2	C2	—	—	—	2	2
ENSG00000307897	02-Medium	0.16	1.71	G2	C2	—	—	—	2	2
ENSG00000299498	02-Medium	0.16	9.30	G2	C2	—	—	—	1	8
ENSG00000287826	02-Medium	0.14	9.32	G2	C2	—	—	—	1	8
LINC02395	02-Medium	0.14	3.42	G2	C2	—	—	—	0	0
PAPSS2	02-Medium	0.13	3.98	G2	C2	DC.cDC2.tolerogenic_regulatory (L2), EPI.pancreatic_ductal_progenitor.biliary_like_xenobiotic (L2), EPI.salivary_serous_acinar.seromucous_like (L2)	MONO.CD14.remodeling (Tier: specific) EPI.salivary_serous_acinar.seromucous_like (Tier: relevant)	59 cells — complete matches	1	2
LINC02651	02-Medium	0.13	3.30	G2	C2	—	—	—	2	0
MAL2	02-Medium	0.13	6.84	G2	C2	—	neuron (Tier: specific) ADIPO.hypoxia_remodelling (Tier: relevant)	35 cells — complete matches	6	10
ORAI1	02-Medium	0.11	4.19	G2	C2	—	—	14 cells — complete matches	18	48

Each hierarchy level is ranked separately. Rows are sorted by score descending; ties use name/identifier order. Measurements are displayed to two decimal places; original values are retained for sorting. Counts and ranks remain whole numbers.

MAGMA −log10(P) describes gene-level association, not the ICE-CREAM cell enrichment score. Individual traits use the minimum available raw MAGMA P value for each gene. Meta traits show the strongest available individual trait evidence among their current children (maximum −log10(P), not the separately aggregated meta-trait P value). The retained top-100 MAGMA export supplements missing gene/individual-trait pairs where identity is unambiguous; its scores are rounded and capped at 350. Full original MAGMA results are unavailable, so child coverage may be incomplete; unavailable values do not mean no association. A raw P recorded as zero is displayed using the existing export convention of 350, not as an exact P value. Positive raw P values are not capped.

Enriched in trait related cells intersects each gene’s membership in the union of up to 100 Enriched-tier genes for each cell population across all available scopes with the Specific and Relevant cells associated with this trait. Gene eligibility requires expression > 0.01 in at least 5% of finite-valued cells and log2 fold change > 2; eligible genes are ranked by descending log2 fold change within each cell/scope, with no lower-tier backfill. The displayed tiers are the authored trait–cell association tiers, not IC-score significance labels. Meta traits use their own aggregate tiers, not a union of child-trait tiers. Marker membership alone does not qualify a cell for this column. A dash means no qualifying intersection in the available evidence.

CSEA (cell set enrichment analysis) is analogous to GSEA: it asks whether a cell set is enriched along a ranked list of ICE-CREAM scores. CSEA FDR is distinct from the existing IC-score Significance category and from the authored trait–cell Tier. CSEA NES is the normalized enrichment score, not a log fold change. Missing evidence is shown as a dash, not zero. Existing IC scores, Significance categories and ranking order are unchanged. For an individual trait, CSEA FDR is the source-adjusted p-value and CSEA NES is the source normalized enrichment score.