Evidence reports Cell populations T.CD4_transitional.APC_interacting DE genes Static evidence for AI interpretation. These reports provide data for prompting AI and are not intended as a human-facing reading interface. Please visit the Cell Browser , Trait Browser and Genome Browser for interactive browsing. Have fun exploring SCREATE!Association counts use unique genes with 01-High Priority evidence and unique cells in the authored Specific tier (not the IC-score significance threshold). Reverse counts list meta traits and individual traits separately; these are overlapping levels of evidence, not independent totals. Counts cover the full available catalogue, not the displayed rows or sampled UMAP. Unavailable profiles are excluded from reverse counts; a dash means unavailable or an ambiguous identity, not zero. The browser initially shows 50 rows; choose Rows to change this. Complete rows remain in the HTML, and ordinary page links expose any continuation pages for AI readers and crawlers.
T.CD4_transitional.APC_interacting: DE genes
How association tiers are defined — cell–trait and gene–trait SCREATE tier definitions supplied by the atlas curator. This methods note explains the prepared classifications; it does not recompute or change any report scores or tiers.
Cell–trait tiers Cell–trait links Identify cell types whose regulatory activity is associated with a trait’s genetic signal. Required for Specific or Relevant The ICE-CREAM score derived from the mean metacell Z score must be ≥ 5.39, with BOTH nominal and adjusted ICE-CREAM P values ≤ 0.05. Specific (Tier 1) Also meets all cell-set enrichment analysis (CSEA) criteria in at least one tested comparison: nominal P ≤ 0.05 AND adjusted P ≤ 0.05 AND normalized enrichment score (NES) ≥ 1, all in that comparison. This indicates that trait-associated activity is concentrated in this cell type relative to the tested background. Relevant (Tier 2) Meets the ICE-CREAM requirements but not the additional CSEA criteria. The cell type may share trait-associated activity with other cell types. Interpretation and report values CSEA is cell-set enrichment analysis, analogous to gene-set enrichment analysis but using sets of cells along a ranked list of ICE-CREAM scores. The eligibility score derived from the mean metacell Z score is not the displayed mean IC score. Do not infer a tier from the displayed mean, its descriptive Significance column, or a single CSEA summary value. Reports preserve prepared tiers; Other means an available association outside Specific/Relevant, and unavailable is not zero or proof of biological irrelevance. Meta traits and individual traits Use the prepared tier for the exact meta trait or individual trait. A meta trait’s Best child CSEA FDR is the lowest available child FDR, not a combined or meta-trait significance test. Its displayed mean child NES is descriptive, not a new CSEA test. These summaries must not be used to reconstruct or override the meta-trait tier. Gene–trait priorities (variant–tCRE–gene evidence) Variant–tCRE–gene links Candidate variants connect to genes through overlapping promoters or distal transcribed cis-regulatory elements (tCREs) linked to gene promoters by the Activity-by-Contact (ABC) model. Required genetic support The variant belongs to a purity-passing SuSiE credible set OR qualifies for Borzoi rescue. Borzoi rescue requires BOTH a variant-causality score ≥ 0.3 AND linkage disequilibrium with the lead variant of r² ≥ 0.2. Required cellular support The overlapping promoter has positive tCRE activity OR the distal element has a passing cell-specific ABC link to the gene, in a Specific or Relevant cell subtype (L1S) or fine-grained state (L2). BOTH genetic and cellular support are required for High or Medium priority. High priority Among records meeting both minimum requirements, High requires a genetic score ≥ 0.5 AND a Layer 1 correlation > 0.3 between tCRE activity and the trait’s cellular profile across cell subtypes. Medium priority Meets both minimum requirements but not one or both additional High thresholds. The genetic score is the higher of the SuSiE posterior inclusion probability (PIP) and the Borzoi variant-causality score. Same-record evidence and aggregation Each priority requires genetic and cellular evidence supporting the SAME variant–tCRE–gene record. Do not combine thresholds or evidence from different records to create a qualifying link. A gene receives the highest priority observed among its supporting records. A tCRE summary uses supporting records for that exact tCRE, not every trait of its linked genes. Separately displayed aggregate scores do not relax the same-record rule. Limits of interpretation A priority is candidate-association evidence, not proof of a causal variant, causal gene, causal cell type or treatment efficacy. Missing evidence is unavailable, not zero. MAGMA −log10(P), displayed credibility scores, cellular-context scores and G/C tier codes must not be substituted for these eligibility tests; use the provided records and their documented fields. Meta traits · Individual traits · Gene expression · DE genes DE log fold change is a different metric from mean expression and IC score. This is the complete available browser export, limited upstream to the top 1,000 genes per population; it is not an exhaustive genome-wide differential-expression result.
All 1,000 available exported DE genes
Browsers # Gene DE log fold change Meta traits (High Priority) Individual traits (High Priority)
1 CCR10 7.61 17 35 2 CCR4 7.02 7 16 3 IL7R 6.90 24 76 4 TXNDC8 6.79 0 0 5 LTB 6.77 127 281 6 CD3E 6.60 17 66 7 CCR8 6.60 5 3 8 FUT7 6.40 22 37 9 CD3D 6.32 18 62 10 CD40LG 5.99 — — 11 CD2 5.94 6 14 12 IL32 5.89 3 5 13 CCR6 5.88 18 26 14 CD52 5.87 10 50 15 TRAT1 5.83 4 9 16 CD3G 5.83 13 55 17 CD5 5.79 23 80 18 PTPRCAP 5.71 7 39 19 CXCL13 5.67 0 0 20 OOEP-AS1 5.67 — — 21 LINC01392 5.65 1 0 22 TNFRSF4 5.61 5 7 23 IL22 5.60 0 0 24 LCK 5.48 0 0 25 CD6 5.44 26 83 26 TTC39C-AS1 5.43 19 15 27 KLRB1 5.35 0 0 28 IL21 5.33 1 1 29 CSF2 5.28 11 34 30 GATA3 5.25 12 44 31 CD69 5.23 0 0 32 CD28 5.22 12 25 33 IL13 5.16 0 0 34 SIT1 5.16 18 57 35 ICOS 5.14 0 2 36 IL2RG 5.12 — — 37 ALOX5AP 5.11 1 0 38 LINC01849 5.09 0 0 39 ITK 5.07 18 59 40 CXCR3 5.05 — — 41 CGA 4.99 0 0 42 HRH4 4.92 0 0 43 GZMA 4.89 8 27 44 LAT 4.88 26 82 45 MCCC1-AS1 4.88 — — 46 ZAP70 4.80 — — 47 CAMK4 4.79 0 0 48 LINC02273 4.72 2 2 49 LINC00452 4.71 — — 50 S100A4 4.71 2 2 51 PTPRC 4.67 14 91 52 CTLA4 4.66 48 101 53 ANKRD55 4.65 3 3 54 LIME1 4.64 58 137 55 CD247 4.62 8 30 56 SPOCK2 4.62 16 24 57 C4orf50 4.61 3 20 58 DUSP4 4.59 0 0 59 JAKMIP1 4.59 3 20 60 PI16 4.59 8 13 61 THEMIS 4.57 0 0 62 CRIP1 4.57 2 11 63 LINC00544 4.56 1 1 64 TNFRSF25 4.55 1 7 65 PTGDR2 4.55 17 65 66 IL26 4.54 0 0 67 SKAP1 4.53 9 21 68 CORO1A 4.51 14 39 69 PMCH 4.50 7 22 70 CD4 4.50 17 28 71 FYB1 4.48 16 33 72 PDCD1 4.48 0 0 73 ITGB7 4.46 3 7 74 GPR25 4.44 2 3 75 RAC2 4.43 7 38 76 BATF 4.43 4 12 77 AQP3 4.43 1 1 78 LEF1 4.42 7 10 79 GPR171 4.40 0 0 80 SELPLG 4.37 13 26 81 MAL 4.37 — — 82 CCR3 4.35 11 25 83 LINC00426 4.33 2 14 84 CD200R1 4.30 11 28 85 CD96 4.30 0 1 86 TNFRSF18 4.29 9 12 87 CPNE7 4.29 22 78 88 HLA-DRB5 4.28 364 756 89 TRAF3IP3 4.27 8 45 90 TCF7 4.27 12 36 91 GATA3-AS1 4.26 16 59 92 TAGAP 4.23 41 93 93 GPR183 4.23 11 28 94 CDCA7 4.22 1 3 95 MSC 4.22 0 0 96 RGS1 4.20 7 12 97 ANXA1 4.20 2 2 98 ARHGAP15 4.20 21 66 99 CD37 4.18 8 15 100 TBC1D10C 4.18 11 36 101 RHOH 4.18 1 2 102 UBASH3A 4.18 17 49 103 SLAMF1 4.17 18 26 104 IL2RA 4.17 9 20 105 CD48 4.16 29 34 106 ADAM8 4.15 6 7 107 TRBV11-2 4.13 — — 108 E2F2 4.13 8 74 109 GRAP2 4.13 6 11 110 CXCR6 4.10 12 25 111 ZC3H12D 4.10 3 3 112 CST7 4.09 — — 113 SAMSN1 4.09 11 22 114 BCL11B 4.07 3 3 115 MYO1G 4.07 19 74 116 GZMM 4.07 2 2 117 DOK2 4.06 20 88 118 CD226 4.06 16 42 119 S1PR4 4.05 13 44 120 CXCR4 4.04 9 38 121 CD27 4.03 20 36 122 LAPTM5 4.03 16 38 123 LINC00861 4.02 6 55 124 ITGB2 4.01 45 135 125 RFPL2 3.99 0 0 126 P2RY10 3.99 — — 127 SUSD3 3.99 28 29 128 LCP1 3.98 7 9 129 SRGN 3.96 34 60 130 BIN2 3.96 12 44 131 SCML4 3.95 3 19 132 FOXP3 3.95 — — 133 ACAP1 3.95 107 149 134 FLT3LG 3.94 72 222 135 POU4F1 3.92 0 0 136 CD7 3.91 7 24 137 HLA-DRB1 3.90 565 1,192 138 IL10RA 3.90 11 12 139 IGFL2 3.87 0 0 140 LINC01727 3.84 1 1 141 TRABD2A 3.83 1 1 142 TESPA1 3.83 6 11 143 GIMAP7 3.82 47 93 144 SIRPG 3.82 5 7 145 HCST 3.82 0 0 146 LINC02520 3.81 2 4 147 LINC02195 3.80 0 0 148 ARHGDIB 3.79 3 8 149 COTL1 3.77 17 66 150 SH2D2A 3.77 8 19 151 TSPAN2 3.76 0 1 152 BTLA 3.76 3 3 153 LINC01871 3.76 0 0 154 HAPLN3 3.76 8 19 155 ITM2A 3.74 — — 156 GLIPR1 3.74 0 1 157 CYTIP 3.74 2 3 158 SH2D1A 3.73 — — 159 GNA15 3.72 9 20 160 SYT4 3.71 0 0 161 PRKCQ 3.71 3 4 162 INPP4B 3.69 1 1 163 PBXIP1 3.67 4 9 164 AIRE 3.66 5 15 165 CD53 3.66 9 18 166 ETS1 3.65 60 88 167 GBP5 3.65 2 2 168 EMB 3.65 — — 169 ADAM19 3.64 14 36 170 PBX4 3.62 51 106 171 ST6GALNAC1 3.61 5 9 172 TIGIT 3.60 1 1 173 LINC01511 3.60 3 3 174 TMEM238 3.60 1 1 175 SAMD3 3.57 2 1 176 NTN5 3.56 86 95 177 GMFG 3.56 1 1 178 ZP1 3.55 17 71 179 LY9 3.55 39 62 180 FXYD5 3.54 87 178 181 IKZF1 3.53 58 153 182 S1PR1 3.53 4 19 183 EVI2B 3.53 — — 184 ARL4C 3.53 1 1 185 DUSP2 3.52 — — 186 KLF2 3.52 52 119 187 OASL 3.52 57 132 188 CYSLTR1 3.51 — — 189 SPN 3.50 4 17 190 CAPG 3.50 33 98 191 FBXL16 3.50 0 0 192 IFITM1 3.50 45 142 193 CLEC2D 3.49 0 0 194 TNFSF14 3.49 22 33 195 GCSAM 3.49 1 17 196 CEACAM21 3.48 5 5 197 SYTL1 3.47 13 29 198 SP140 3.47 8 23 199 MAP4K1 3.47 14 38 200 TC2N 3.46 7 9 201 ARHGAP30 3.46 13 25 202 PIM2 3.45 — — 203 SYTL3 3.45 2 7 204 MEI1 3.45 31 94 205 HLA-DQB1 3.44 703 1,314 206 HCLS1 3.44 18 46 207 LIMD2 3.43 7 34 208 GIMAP5 3.43 34 64 209 ISG20 3.40 7 21 210 TMC8 3.40 25 96 211 CD82 3.38 4 13 212 KCNA3 3.38 2 2 213 RGCC 3.38 1 4 214 GPSM3 3.38 358 590 215 LCP2 3.38 2 6 216 ITGB2-AS1 3.37 42 129 217 C16orf54 3.37 2 2 218 DEF6 3.36 23 105 219 LSP1 3.36 41 132 220 PTPN7 3.36 5 9 221 RCAN3 3.35 6 8 222 TNFSF8 3.35 41 70 223 EVL 3.34 10 22 224 TNF 3.34 75 194 225 PYHIN1 3.34 14 29 226 RASGRP1 3.33 3 7 227 TNFAIP3 3.33 19 50 228 NUGGC 3.32 9 13 229 MYO1F 3.32 66 278 230 ICAM3 3.32 28 48 231 TGFB1 3.32 29 68 232 SNAI3 3.31 23 73 233 LGALS1 3.30 22 66 234 CRYGN 3.29 3 7 235 LINC01943 3.29 2 2 236 RASAL3 3.28 5 10 237 IL21R 3.28 13 27 238 ANO9 3.28 2 6 239 GIMAP4 3.27 44 105 240 IL4 3.26 54 93 241 SLAMF6 3.26 14 14 242 C1orf162 3.26 1 3 243 CCR7 3.23 28 100 244 CORO2A 3.23 7 9 245 EMP3 3.22 0 0 246 PSTPIP1 3.22 6 6 247 JAML 3.21 15 57 248 IL5RA 3.21 1 7 249 PRDM1 3.21 2 2 250 CCL5 3.21 9 22 251 TUBA4A 3.19 4 18 252 GPR174 3.18 — — 253 MFHAS1 3.18 51 225 254 IL2 3.18 2 2 255 ARHGAP45 3.17 43 188 256 RIPOR2 3.17 11 46 257 IL17RB 3.16 14 28 258 WNT10A 3.16 13 85 259 PRF1 3.15 6 16 260 RAB37 3.11 13 58 261 MFNG 3.11 6 19 262 UCP2 3.11 1 1 263 PASK 3.11 3 8 264 WAS 3.10 — — 265 SLFN12L 3.10 50 75 266 PTGER4 3.10 7 24 267 CDC25B 3.09 10 38 268 CD84 3.09 16 23 269 CRIP2 3.09 0 0 270 SASH3 3.09 — — 271 TMEM200A 3.09 1 1 272 KRTAP16-1 3.08 0 0 273 CD101 3.08 6 22 274 CASS4 3.08 2 9 275 HLA-DQA1 3.07 608 1,232 276 SH3BP1 3.07 15 37 277 SLC2A3 3.06 6 6 278 IL16 3.06 6 11 279 ETV7 3.06 17 22 280 NLRC3 3.06 5 16 281 LAX1 3.06 6 14 282 STAT4 3.06 2 3 283 NDC80 3.05 0 0 284 ITFG1-AS1 3.05 1 1 285 C20orf204 3.04 20 56 286 RGL4 3.04 0 0 287 IL2RB 3.04 15 52 288 PAG1 3.03 2 3 289 ATP2A3 3.03 3 3 290 SLA2 3.03 9 19 291 CARMIL2 3.02 17 56 292 DENND1C 3.02 9 12 293 GIMAP1 3.02 30 57 294 GIMAP1-GIMAP5 3.02 30 57 295 PLA2G2C 3.01 0 0 296 LINC01870 3.01 0 0 297 JAK3 3.01 6 8 298 FMNL1 3.00 18 39 299 PLP2 3.00 — — 300 GDPD5 2.99 4 4 301 FXYD7 2.99 75 144 302 PVRIG 2.98 11 39 303 LINC01801 2.97 52 101 304 THEM5 2.97 0 0 305 SNX20 2.96 6 13 306 HLA-DQA2 2.95 173 495 307 C12orf75 2.95 0 0 308 IFNG 2.95 0 0 309 FCMR 2.95 23 28 310 CALHM1 2.94 3 8 311 TNFRSF1B 2.94 10 16 312 IL12RB1 2.94 47 133 313 HLA-DPA1 2.94 287 545 314 CDKN2D 2.94 4 30 315 BIRC3 2.94 1 1 316 OCIAD2 2.94 0 0 317 PTPN22 2.93 73 148 318 PKIA 2.92 1 0 319 NCKAP1L 2.92 5 11 320 B2M 2.92 0 0 321 SLC9A9-AS2 2.92 — — 322 ITGA4 2.92 22 102 323 LTA 2.92 226 418 324 TPPP 2.92 2 3 325 HOPX 2.91 5 7 326 LPO 2.91 0 0 327 LINC01891 2.90 0 0 328 AGAP2 2.90 11 40 329 TNFSF11 2.90 0 5 330 IL27RA 2.90 10 37 331 SH2D3A 2.89 16 37 332 LINC00536 2.89 1 8 333 ROPN1L 2.89 0 0 334 PRKCH 2.89 3 4 335 PIK3R5 2.88 13 40 336 IL23A 2.87 0 1 337 DDX4 2.86 1 5 338 LINC02150 2.86 0 0 339 CARD11 2.85 11 26 340 TRADD 2.85 13 23 341 RASGRP2 2.85 5 11 342 CYTOR 2.85 2 2 343 POU3F1 2.85 2 14 344 SH3BGRL3 2.84 18 62 345 NCR3 2.84 261 542 346 S100A10 2.84 5 10 347 CHST7 2.83 — — 348 RNF125 2.83 5 4 349 NELL2 2.83 0 0 350 CASP8 2.82 24 62 351 LINC01215 2.82 5 18 352 GPR65 2.82 12 17 353 DNAI2 2.82 13 34 354 AKAP14 2.82 — — 355 RGS19 2.81 24 68 356 FGD3 2.81 23 23 357 STMN3 2.81 62 155 358 TBXAS1 2.81 5 10 359 FBLN7 2.80 2 3 360 CD74 2.80 13 14 361 HLA-DRA 2.80 693 1,237 362 GOLGA7B 2.79 2 1 363 SH3PXD2A-AS1 2.78 1 4 364 APOBEC3H 2.78 11 23 365 LINC02390 2.78 0 0 366 FERMT3 2.77 17 63 367 CCDC167 2.77 0 0 368 ITPRIPL1 2.77 — — 369 TSC22D3 2.76 — — 370 RUNX2 2.76 3 12 371 LRFN4 2.76 6 7 372 ORAI1 2.76 18 48 373 CCDC88C 2.75 8 36 374 NOS3 2.75 43 95 375 CYTH4 2.75 4 21 376 ITGAL 2.74 25 90 377 ZNF365 2.74 19 27 378 FAS 2.74 5 7 379 CSGALNACT1 2.74 17 41 380 SLA 2.74 6 26 381 OSM 2.73 19 68 382 CA5B 2.73 — — 383 RGS10 2.72 8 23 384 C2CD4D 2.72 0 0 385 EIF4E3 2.72 2 2 386 VIM 2.71 32 102 387 CD44 2.70 4 5 388 ADORA2A 2.70 17 26 389 GNG2 2.70 1 1 390 LINC01550 2.69 1 1 391 MCOLN2 2.68 1 1 392 CD177 2.68 2 3 393 TMSB4X 2.68 — — 394 HLA-DPB1 2.68 293 562 395 IQGAP2 2.68 26 84 396 TRERF1 2.68 13 56 397 IL17RE 2.67 2 2 398 RAB11FIP5 2.67 0 1 399 CNN2 2.67 27 139 400 ICAM2 2.66 18 29 401 BRDT 2.66 5 4 402 NCF4 2.65 7 38 403 RUNX3 2.65 86 173 404 ABRACL 2.64 5 13 405 LINC00243 2.64 192 416 406 HLA-B 2.64 493 836 407 SPATA13-AS1 2.64 2 4 408 IL17F 2.64 0 0 409 APOBEC3G 2.63 7 11 410 SPATA45 2.63 0 0 411 PIK3CD 2.63 5 45 412 LOXL1-AS1 2.62 44 98 413 MIAT 2.62 1 1 414 FLI1 2.61 61 103 415 EEPD1 2.61 16 45 416 HLA-C 2.60 738 1,070 417 HLA-A 2.59 281 510 418 PPP1R16B 2.59 4 3 419 SMC1B 2.58 6 10 420 LINC02022 2.58 4 6 421 MPZL3 2.58 16 59 422 RASSF5 2.58 13 29 423 LINC00392 2.58 — — 424 ARHGAP9 2.58 20 49 425 TTC9 2.58 1 1 426 TNFAIP8 2.58 21 107 427 CALHM2 2.58 7 15 428 UBE2R2-AS1 2.58 7 13 429 GLB1L3 2.58 1 1 430 RCSD1 2.57 7 20 431 LBH 2.57 9 20 432 FAM107B 2.57 1 5 433 TAGLN2 2.57 13 26 434 CCNI2 2.57 1 1 435 SNED1 2.57 3 5 436 TOX 2.56 1 2 437 TAP1 2.56 201 382 438 LMNA 2.56 18 37 439 HPCAL4 2.56 7 28 440 GPRIN3 2.55 5 10 441 GLIPR2 2.55 2 2 442 GADD45G 2.54 40 113 443 PCED1B 2.54 2 6 444 S100A11 2.54 3 3 445 ATG9B 2.54 14 20 446 CISH 2.54 23 66 447 TTC39C 2.54 22 28 448 FAM117A 2.54 4 16 449 PROK2 2.54 1 1 450 CARD16 2.53 2 2 451 MAF 2.53 0 0 452 AGMAT 2.53 3 6 453 TSHZ2 2.52 6 14 454 LINC00324 2.52 11 25 455 CCDC65 2.52 2 3 456 MCF2L2 2.52 3 9 457 LPAR6 2.52 0 0 458 BTBD6 2.52 0 0 459 TNFAIP8L2 2.52 11 38 460 MORN3 2.51 14 37 461 DAPP1 2.51 35 104 462 GPR68 2.51 0 2 463 RASA3 2.51 9 52 464 ARHGAP11A 2.50 0 0 465 EZR 2.50 6 21 466 LINC00944 2.50 0 1 467 GTSF1 2.50 3 8 468 LTK 2.50 2 7 469 TMSB10 2.50 1 1 470 ANXA2R 2.49 1 0 471 RILPL2 2.49 24 92 472 ANXA6 2.48 13 39 473 CDKN2A 2.48 3 4 474 LAIR2 2.48 6 8 475 GIMAP2 2.48 37 96 476 RORA 2.48 17 20 477 ZBP1 2.48 12 68 478 RTKN2 2.47 21 42 479 JUNB 2.47 9 31 480 TLX2 2.47 0 0 481 PSMB9 2.46 227 422 482 DOCK2 2.46 1 1 483 LINC00589 2.46 0 0 484 SAMHD1 2.46 9 18 485 RAB33A 2.46 — — 486 ZFYVE28 2.45 1 0 487 RNPEPL1 2.45 5 11 488 MCUB 2.45 0 0 489 OAS2 2.44 8 25 490 GPR146 2.44 19 73 491 HLA-E 2.44 193 384 492 LINC00649 2.44 10 41 493 GPR132 2.44 2 2 494 GRK6 2.44 51 66 495 EVI2A 2.44 — — 496 PLD6 2.43 3 21 497 NRIP3 2.43 0 0 498 GRAP 2.43 0 0 499 PTTG1 2.43 0 0 500 TSPAN18 2.42 2 12 501 EDARADD 2.42 1 1 502 LPAR2 2.41 15 30 503 KCNN4 2.41 27 66 504 GIMAP6 2.41 42 95 505 F8A3 2.41 — — 506 CORO7 2.41 20 57 507 PPP1R18 2.41 153 285 508 CHRM3-AS2 2.40 2 1 509 STK10 2.39 21 35 510 TNFRSF10A 2.39 15 44 511 GALM 2.39 1 10 512 TSTD1 2.39 23 36 513 PLEKHF1 2.39 0 0 514 LFNG 2.39 5 9 515 CTSW 2.39 22 46 516 CENPM 2.39 29 65 517 TMEM156 2.38 8 15 518 PVT1 2.38 1 1 519 RPS29 2.37 1 1 520 CCR2 2.37 25 71 521 FASLG 2.37 0 0 522 PLSCR3 2.37 8 11 523 ZFP36L2 2.37 39 140 524 NINJ2 2.37 15 54 525 CENPK 2.37 0 0 526 LDHB 2.36 18 32 527 LEPROTL1 2.36 0 3 528 ZNF831 2.36 20 88 529 IGFLR1 2.35 1 1 530 DENND2D 2.35 4 12 531 SLC38A5 2.35 — — 532 AKNA 2.35 49 78 533 RNASET2 2.35 29 62 534 KIAA0825 2.35 0 0 535 SLF1 2.34 0 0 536 TNFSF10 2.34 15 24 537 DUSP5 2.34 0 0 538 AHNAK 2.34 15 31 539 ARRB2 2.34 14 58 540 STK17B 2.34 5 39 541 GZMK 2.34 8 21 542 RPS6KA1 2.34 13 54 543 PSMB8-AS1 2.34 204 380 544 VAV1 2.33 11 25 545 SLC38A1 2.33 0 1 546 RGS14 2.33 108 243 547 LRRC8C 2.32 2 6 548 SLC5A2 2.32 0 0 549 AGFG2 2.32 21 63 550 CENPE 2.31 2 1 551 FAR2 2.31 0 0 552 PIK3IP1 2.31 11 41 553 FOXD2 2.31 12 28 554 IL6R 2.31 65 111 555 LINC01257 2.30 0 2 556 CNTNAP1 2.30 8 21 557 RNF166 2.30 28 105 558 ABCD2 2.30 1 1 559 ADGRE5 2.29 10 72 560 CDC14A 2.29 2 7 561 SELL 2.29 26 113 562 CHST11 2.29 0 0 563 LINC00539 2.29 0 0 564 IKBKE 2.28 14 34 565 PCSK1N 2.28 — — 566 SAMD10 2.28 16 34 567 DLEC1 2.28 3 2 568 VWA8-AS1 2.28 0 0 569 NLRC5 2.27 54 163 570 LINC02265 2.26 9 12 571 ITGB1 2.26 2 3 572 INPP5D 2.26 15 58 573 RBM38 2.26 8 67 574 GPR55 2.26 3 2 575 MICB 2.26 294 633 576 LINC01934 2.26 11 42 577 HMSD 2.25 6 8 578 CYB561 2.25 14 41 579 SLFN5 2.25 3 5 580 NCK2 2.25 2 7 581 TRAF1 2.24 13 34 582 MIR155HG 2.24 0 0 583 ZC3HAV1 2.24 8 52 584 PTPN6 2.23 0 0 585 ACP5 2.23 6 8 586 PPM1M 2.23 86 217 587 CMTM3 2.23 23 32 588 MAP3K1 2.23 8 14 589 FNDC11 2.22 20 64 590 WDR86 2.22 4 7 591 TRIM59 2.22 0 0 592 TRG-AS1 2.21 3 4 593 UMODL1 2.21 2 1 594 KIF5C 2.21 0 0 595 ARPC1B 2.21 27 109 596 PRKX 2.21 — — 597 S100A5 2.20 0 0 598 HELB 2.20 3 6 599 CSK 2.20 22 76 600 DNLZ 2.20 58 218 601 NFATC2 2.19 8 23 602 SEL1L3 2.19 8 10 603 FAAH2 2.19 — — 604 CHEK1 2.19 1 1 605 SEMA4D 2.19 4 15 606 DOCK8 2.19 18 82 607 DMTN 2.18 20 53 608 ARHGEF6 2.18 — — 609 APOBEC3C 2.18 3 3 610 KIF23 2.18 0 0 611 EFCAB12 2.18 0 0 612 TBX21 2.18 13 31 613 PIM1 2.18 34 81 614 BICDL1 2.17 1 1 615 GSTK1 2.17 6 11 616 GBP2 2.17 0 0 617 KCNAB2 2.17 7 165 618 TSPAN32 2.16 17 78 619 MAPK11 2.16 8 15 620 PPP2R5C 2.16 3 4 621 RPS27 2.15 11 53 622 MZT2A 2.15 0 0 623 TSPOAP1-AS1 2.15 6 11 624 HACD4 2.15 1 0 625 LHX1 2.15 0 0 626 GPR15 2.14 1 1 627 CYBA 2.14 28 69 628 ANXA2 2.14 8 11 629 PFN1 2.14 6 35 630 CD79B 2.14 5 11 631 KCNA2 2.14 5 5 632 TRPM2-AS 2.13 10 39 633 R3HDM4 2.13 28 78 634 QPRT 2.13 5 18 635 FLNA 2.13 — — 636 NMU 2.13 0 0 637 PHLDA1 2.13 0 1 638 MAPK13 2.13 10 16 639 DRAIC 2.13 2 1 640 PLEKHN1 2.13 2 4 641 CATSPERD 2.12 14 13 642 PSMB8 2.12 200 385 643 FAM89B 2.12 3 6 644 NETO2 2.11 1 1 645 RASSF7 2.11 10 24 646 RLN1 2.11 1 0 647 PIK3CG 2.11 1 3 648 CAPN12 2.10 36 54 649 LINC02361 2.10 11 17 650 MYL12A 2.10 1 3 651 ATP6V0E2 2.10 10 18 652 ST8SIA1 2.10 3 4 653 RGS16 2.10 5 5 654 NOX5 2.10 0 0 655 LY75 2.09 11 46 656 LY75-CD302 2.09 11 46 657 MED14OS 2.09 — — 658 AIM2 2.09 13 30 659 PARP8 2.09 — — 660 NFE2L3 2.09 1 1 661 GPR27 2.09 2 2 662 LINC02240 2.08 3 6 663 STK4 2.08 35 58 664 MYADM 2.08 19 22 665 HLA-F 2.07 205 352 666 LINC01393 2.07 7 37 667 BCL9L 2.07 26 50 668 CORO1B 2.07 11 38 669 IKZF3 2.07 83 204 670 ZDHHC18 2.07 80 389 671 ASF1A 2.07 3 7 672 OPTN 2.07 1 1 673 MDFIC 2.07 0 46 674 SH3BP5 2.06 2 2 675 CASTOR1 2.06 16 68 676 S100A6 2.06 3 4 677 DOCK10 2.06 6 33 678 MSC-AS1 2.05 0 0 679 SOCS1 2.05 7 11 680 SMAP2 2.05 5 17 681 CHDH 2.05 18 34 682 LINC02539 2.05 11 26 683 LMNB1 2.05 2 5 684 GMIP 2.05 30 114 685 KIF21B 2.04 0 1 686 CKAP2L 2.04 6 23 687 CEP55 2.04 0 0 688 IFITM2 2.03 53 160 689 TMC6 2.03 18 74 690 UNC13D 2.03 70 166 691 PLEC 2.03 97 195 692 MICAL1 2.03 23 131 693 ELK3 2.03 1 2 694 LINC00299 2.03 6 15 695 PRR5L 2.03 0 0 696 CDC42SE2 2.02 9 9 697 WDR76 2.02 4 5 698 LINC00511 2.02 0 0 699 DGKA 2.02 0 0 700 HTR2B 2.02 9 13 701 CDHR3 2.01 0 0 702 MIR4435-2HG 2.01 13 33 703 PFKP 2.01 1 1 704 ADCY7 2.00 5 10 705 RAP1GAP2 2.00 4 8 706 KLF16 2.00 6 7 707 GYPC 1.99 3 4 708 RPS12 1.99 3 3 709 ARHGAP25 1.99 17 54 710 VWA7 1.99 1 1 711 B3GNT9 1.99 16 33 712 SH3KBP1 1.98 — — 713 HPGD 1.98 0 0 714 SLC7A5 1.98 17 47 715 CCND3 1.98 26 125 716 RPL28 1.98 3 3 717 NPDC1 1.98 19 47 718 ST8SIA4 1.98 1 1 719 MMP25 1.98 3 9 720 GRK2 1.98 1 7 721 TRAF5 1.98 0 0 722 CRACR2A 1.97 2 5 723 F5 1.97 27 137 724 MIR3142HG 1.97 1 1 725 RPL41 1.97 2 2 726 RPS27A 1.97 0 0 727 RAB39B 1.96 — — 728 LINC01259 1.96 2 3 729 RPS18 1.96 17 39 730 LY96 1.96 3 3 731 TOX2 1.96 10 31 732 ATP8B3 1.96 6 8 733 ITPR3 1.96 9 32 734 ACE 1.96 11 44 735 BTN3A2 1.96 124 241 736 HECA 1.96 4 6 737 TNFSF12-TNFSF13 1.95 32 67 738 PREX1 1.95 9 40 739 OOEP 1.95 0 0 740 LGALS3 1.95 7 33 741 E2F1 1.95 5 7 742 WIPF1 1.95 1 5 743 TAP2 1.95 198 364 744 TMEM154 1.94 0 0 745 EPSTI1 1.94 0 0 746 RASSF3 1.94 9 29 747 LETM2 1.94 0 0 748 SUN2 1.94 17 55 749 TMEM102 1.94 16 26 750 TNFSF12 1.94 31 66 751 PSD4 1.94 45 133 752 TRIB2 1.93 3 4 753 CD109 1.93 0 0 754 GLB1L2 1.93 1 1 755 MKI67 1.93 0 0 756 RNF222 1.93 1 1 757 RIPK3 1.93 13 23 758 LINC01825 1.92 5 36 759 RPL34 1.92 1 4 760 CD70 1.92 9 14 761 TMEM169 1.92 0 0 762 LINC01389 1.92 7 8 763 RPL18A 1.92 4 6 764 FAM110A 1.91 2 2 765 RPS21 1.91 14 50 766 KLHL6 1.91 2 8 767 PMAIP1 1.90 2 4 768 NUSAP1 1.90 1 3 769 VAMP8 1.90 38 110 770 P2RX5 1.90 2 2 771 UBALD2 1.89 3 4 772 MTFP1 1.89 11 44 773 TNIK 1.89 61 202 774 RPL30 1.89 3 9 775 SARAF 1.89 0 0 776 EHD1 1.89 8 21 777 FKBP11 1.89 2 7 778 RPL39 1.89 — — 779 CBX4 1.88 3 3 780 TCAF2 1.88 6 10 781 LINC00920 1.88 17 19 782 CMTM7 1.88 2 2 783 SPATA3-AS1 1.88 0 1 784 CCND2 1.88 11 45 785 CYLD 1.88 5 10 786 RPS19 1.88 1 2 787 ARHGEF18 1.87 8 13 788 TOB1 1.87 0 0 789 CYFIP2 1.87 22 66 790 MAZ 1.87 2 2 791 TBCC 1.87 6 26 792 ANKRD44 1.87 10 64 793 DPP4 1.86 0 0 794 PSME1 1.86 0 0 795 ARL6IP5 1.86 0 0 796 LY6E 1.86 0 0 797 GBP4 1.86 2 2 798 LGALS9 1.86 — — 799 RORC 1.86 0 0 800 LAG3 1.86 12 24 801 LINC01806 1.85 3 3 802 NEFL 1.85 0 0 803 RPS4X 1.85 — — 804 RPS15A 1.85 1 1 805 GALNT6 1.85 12 45 806 PARPBP 1.85 0 0 807 SOCS3 1.84 33 147 808 BTN3A1 1.84 35 65 809 AP1G2 1.84 1 0 810 NCAPG 1.84 1 1 811 CENPB 1.84 10 31 812 ADA2 1.84 7 7 813 C5orf67 1.84 1 3 814 RPS10-NUDT3 1.84 20 45 815 RASSF2 1.84 3 4 816 ATP8B2 1.84 33 81 817 RPS10 1.84 20 45 818 NOSIP 1.84 74 241 819 RHOG 1.83 9 22 820 LRRC56 1.83 0 0 821 RPS3 1.83 0 0 822 ELF1 1.83 33 104 823 RPL19 1.83 0 0 824 PDCL3 1.82 1 1 825 PPP1CA 1.82 6 27 826 IL23R 1.82 2 2 827 ZNF331 1.82 1 1 828 TMEM250 1.81 1 1 829 TTC22 1.81 9 32 830 TRIM46 1.81 3 4 831 JUND 1.81 32 94 832 PLA2G4E-AS1 1.80 48 174 833 THAP11 1.80 0 0 834 ERN1 1.80 23 38 835 JPT1 1.80 10 22 836 AP4B1-AS1 1.80 73 147 837 IPCEF1 1.79 1 1 838 HNRNPLL 1.79 1 10 839 CHRNA6 1.79 — — 840 NLRP1 1.79 3 4 841 OR2A1-AS1 1.79 2 6 842 P2RX5-TAX1BP3 1.79 2 2 843 ARHGEF3 1.79 12 17 844 NSG1 1.79 0 0 845 ACSL6 1.79 5 2 846 VSIR 1.79 47 94 847 RPL32 1.79 3 5 848 CKLF-CMTM1 1.79 14 14 849 SAMD9L 1.78 1 1 850 SYT11 1.78 0 0 851 MBP 1.78 1 12 852 PLCB2 1.78 4 13 853 BTG1 1.78 4 19 854 SLC2A4RG 1.78 47 130 855 NR4A3 1.78 0 0 856 HLA-G 1.78 74 109 857 BFSP2 1.78 0 1 858 IL4R 1.78 9 47 859 RINL 1.78 12 21 860 LINC02099 1.77 0 0 861 PXN 1.77 9 12 862 TMEM204 1.77 9 18 863 VIPR1 1.77 0 0 864 STXBP2 1.77 9 10 865 SAMD9 1.77 0 0 866 LMO4 1.76 0 0 867 CKLF 1.76 7 8 868 RPLP1 1.76 0 0 869 TXN 1.76 0 0 870 XCL1 1.76 5 13 871 DIAPH1 1.76 4 3 872 BUB1 1.76 4 9 873 KIF20B 1.76 2 2 874 TSPO 1.75 13 39 875 SLC9A9 1.75 5 17 876 ERAP2 1.75 31 57 877 PRR5 1.75 2 1 878 DPEP2 1.75 25 58 879 GALNT12 1.75 9 37 880 RPL36 1.75 1 11 881 PHLDB3 1.75 17 31 882 ATAD3C 1.75 7 20 883 CD58 1.74 3 4 884 FAU 1.74 8 10 885 CEND1 1.74 1 3 886 CITED2 1.74 4 27 887 PRR19 1.74 0 0 888 RHOF 1.74 39 108 889 ARF6 1.74 0 0 890 GABRR1 1.74 1 1 891 RPL37 1.74 3 4 892 LINC01865 1.73 2 5 893 STK17A 1.73 4 22 894 TGFBR3 1.73 15 26 895 LINC02228 1.73 0 0 896 FAM78A 1.73 0 0 897 KNDC1 1.73 14 21 898 MREG 1.73 1 2 899 GRAPL 1.73 0 0 900 PARP15 1.73 6 21 901 NHLRC4 1.73 7 15 902 ULBP2 1.72 0 0 903 RCBTB2 1.72 1 3 904 RHNO1 1.72 2 20 905 RPSA 1.72 7 12 906 LINC02391 1.72 4 18 907 RPL23A 1.72 — — 908 ZBTB20-AS5 1.72 1 1 909 CEP19 1.72 8 31 910 BLM 1.71 26 52 911 LINC01765 1.71 0 1 912 DEDD2 1.71 1 1 913 ADCY3 1.71 25 66 914 PPP1R3F 1.71 — — 915 SORL1 1.70 0 0 916 VIM-AS1 1.70 32 101 917 ATF7IP2 1.70 6 10 918 AHR 1.70 9 22 919 RFX8 1.70 2 3 920 SYNE3 1.70 1 6 921 HMOX2 1.70 26 53 922 PCAT1 1.70 2 1 923 CRYBG1 1.70 1 1 924 LINC02325 1.69 0 0 925 CTSC 1.69 11 29 926 SHKBP1 1.69 38 102 927 CFL1 1.69 24 101 928 RRS1 1.69 0 0 929 RPL35A 1.69 0 0 930 NBEAL2 1.69 74 146 931 GGT1 1.69 14 23 932 SQOR 1.69 3 3 933 RTP5 1.68 4 14 934 MYD88 1.68 2 1 935 KLF12 1.68 10 39 936 DCK 1.68 0 1 937 RPL26 1.68 4 5 938 PRKCZ 1.68 8 47 939 OTUD1 1.67 1 1 940 MX2 1.67 12 17 941 SRXN1 1.67 0 0 942 EPS8L2 1.67 13 20 943 RNF157 1.67 0 1 944 OSTF1 1.67 1 1 945 PLEKHO1 1.67 1 1 946 TOP2A 1.66 20 58 947 NR4A2 1.66 1 1 948 NAALADL1 1.66 0 0 949 CRYBG2 1.66 13 44 950 ISG15 1.66 7 10 951 DGKZ 1.66 61 373 952 TWF2 1.66 72 151 953 ELOVL5 1.66 4 12 954 FYN 1.66 3 7 955 LINC00623 1.66 0 0 956 LRFN3 1.66 0 0 957 IER5 1.66 5 20 958 MGAT4A 1.66 5 10 959 SFMBT1 1.66 65 186 960 ACSL5 1.66 52 149 961 EEF1A1 1.66 6 8 962 SLC14A1 1.66 3 16 963 DDIT4 1.65 4 4 964 GBP1 1.65 1 2 965 B9D2 1.65 23 46 966 RBM15B 1.65 0 0 967 RPS14 1.65 5 5 968 SYNE2 1.65 7 21 969 LYL1 1.65 18 63 970 PARD6A 1.65 17 56 971 ZNF296 1.65 2 3 972 CDKN1B 1.65 4 21 973 MCM6 1.65 9 22 974 SSBP4 1.65 40 83 975 IFFO2 1.64 1 3 976 PGAM4 1.64 — — 977 MAD2L1 1.64 2 2 978 CREM 1.64 0 0 979 MAP6 1.64 3 3 980 UBA52 1.64 37 60 981 SEC11C 1.64 1 1 982 FAM24B 1.64 8 15 983 RPS15 1.63 0 0 984 APOL3 1.63 17 42 985 CHD3 1.63 21 35 986 RTL6 1.63 0 0 987 LINC00402 1.63 5 10 988 RPL29 1.63 1 10 989 LPXN 1.63 7 17 990 BAK1 1.63 19 57 991 EPHA4 1.63 0 0 992 ARID5B 1.63 29 74 993 TPX2 1.63 — — 994 ITPKB 1.63 4 9 995 SLC16A6 1.62 4 10 996 RAD51 1.62 7 7 997 ENO2 1.62 0 0 998 PNMA1 1.62 8 12 999 RPLP2 1.62 13 34 1000 RNF19B 1.62 1 3