Evidence reports Cell populations MAC.proliferating.DNA_replication DE genes Static evidence for AI interpretation. These reports provide data for prompting AI and are not intended as a human-facing reading interface. Please visit the Cell Browser , Trait Browser and Genome Browser for interactive browsing. Have fun exploring SCREATE!Association counts use unique genes with 01-High Priority evidence and unique cells in the authored Specific tier (not the IC-score significance threshold). Reverse counts list meta traits and individual traits separately; these are overlapping levels of evidence, not independent totals. Counts cover the full available catalogue, not the displayed rows or sampled UMAP. Unavailable profiles are excluded from reverse counts; a dash means unavailable or an ambiguous identity, not zero. The browser initially shows 50 rows; choose Rows to change this. Complete rows remain in the HTML, and ordinary page links expose any continuation pages for AI readers and crawlers.
MAC.proliferating.DNA_replication: DE genes
How association tiers are defined — cell–trait and gene–trait SCREATE tier definitions supplied by the atlas curator. This methods note explains the prepared classifications; it does not recompute or change any report scores or tiers.
Cell–trait tiers Cell–trait links Identify cell types whose regulatory activity is associated with a trait’s genetic signal. Required for Specific or Relevant The ICE-CREAM score derived from the mean metacell Z score must be ≥ 5.39, with BOTH nominal and adjusted ICE-CREAM P values ≤ 0.05. Specific (Tier 1) Also meets all cell-set enrichment analysis (CSEA) criteria in at least one tested comparison: nominal P ≤ 0.05 AND adjusted P ≤ 0.05 AND normalized enrichment score (NES) ≥ 1, all in that comparison. This indicates that trait-associated activity is concentrated in this cell type relative to the tested background. Relevant (Tier 2) Meets the ICE-CREAM requirements but not the additional CSEA criteria. The cell type may share trait-associated activity with other cell types. Interpretation and report values CSEA is cell-set enrichment analysis, analogous to gene-set enrichment analysis but using sets of cells along a ranked list of ICE-CREAM scores. The eligibility score derived from the mean metacell Z score is not the displayed mean IC score. Do not infer a tier from the displayed mean, its descriptive Significance column, or a single CSEA summary value. Reports preserve prepared tiers; Other means an available association outside Specific/Relevant, and unavailable is not zero or proof of biological irrelevance. Meta traits and individual traits Use the prepared tier for the exact meta trait or individual trait. A meta trait’s Best child CSEA FDR is the lowest available child FDR, not a combined or meta-trait significance test. Its displayed mean child NES is descriptive, not a new CSEA test. These summaries must not be used to reconstruct or override the meta-trait tier. Gene–trait priorities (variant–tCRE–gene evidence) Variant–tCRE–gene links Candidate variants connect to genes through overlapping promoters or distal transcribed cis-regulatory elements (tCREs) linked to gene promoters by the Activity-by-Contact (ABC) model. Required genetic support The variant belongs to a purity-passing SuSiE credible set OR qualifies for Borzoi rescue. Borzoi rescue requires BOTH a variant-causality score ≥ 0.3 AND linkage disequilibrium with the lead variant of r² ≥ 0.2. Required cellular support The overlapping promoter has positive tCRE activity OR the distal element has a passing cell-specific ABC link to the gene, in a Specific or Relevant cell subtype (L1S) or fine-grained state (L2). BOTH genetic and cellular support are required for High or Medium priority. High priority Among records meeting both minimum requirements, High requires a genetic score ≥ 0.5 AND a Layer 1 correlation > 0.3 between tCRE activity and the trait’s cellular profile across cell subtypes. Medium priority Meets both minimum requirements but not one or both additional High thresholds. The genetic score is the higher of the SuSiE posterior inclusion probability (PIP) and the Borzoi variant-causality score. Same-record evidence and aggregation Each priority requires genetic and cellular evidence supporting the SAME variant–tCRE–gene record. Do not combine thresholds or evidence from different records to create a qualifying link. A gene receives the highest priority observed among its supporting records. A tCRE summary uses supporting records for that exact tCRE, not every trait of its linked genes. Separately displayed aggregate scores do not relax the same-record rule. Limits of interpretation A priority is candidate-association evidence, not proof of a causal variant, causal gene, causal cell type or treatment efficacy. Missing evidence is unavailable, not zero. MAGMA −log10(P), displayed credibility scores, cellular-context scores and G/C tier codes must not be substituted for these eligibility tests; use the provided records and their documented fields. Meta traits · Individual traits · Gene expression · DE genes DE log fold change is a different metric from mean expression and IC score. This is the complete available browser export, limited upstream to the top 1,000 genes per population; it is not an exhaustive genome-wide differential-expression result.
All 1,000 available exported DE genes
Browsers # Gene DE log fold change Meta traits (High Priority) Individual traits (High Priority)
1 FABP4 10.95 3 1 2 MMP9 10.42 54 374 3 TREM2 9.98 1 1 4 C1QC 9.92 1 1 5 C1QB 9.45 1 1 6 SPP1 9.20 7 18 7 UBE2C 8.83 9 25 8 C1QA 8.47 1 1 9 APOC1 8.46 301 1,434 10 TYROBP 8.39 7 9 11 CHIT1 8.32 11 18 12 IFI30 8.30 34 83 13 PLA2G7 8.09 3 4 14 BIRC5 8.07 15 62 15 MS4A4A 8.04 41 76 16 CD68 8.02 33 81 17 TM4SF19 8.00 2 2 18 PRRX2-AS1 7.97 — — 19 RRM2 7.92 6 6 20 PCLAF 7.89 2 3 21 TK1 7.87 15 62 22 SLAMF9 7.72 3 2 23 PKMYT1 7.69 0 1 24 FCER1G 7.63 104 220 25 MS4A6E 7.53 77 122 26 TYMS 7.53 5 5 27 MKI67 7.52 0 0 28 CDK1 7.46 11 11 29 GTSE1 7.40 0 2 30 CDCA3 7.34 12 24 31 SPC25 7.33 13 44 32 LINC01872 7.31 2 2 33 IGSF6 7.26 0 0 34 CCNA2 7.26 0 0 35 IL1RN 7.24 37 108 36 LYZ 7.19 7 24 37 CHI3L1 7.19 9 14 38 DCSTAMP 7.13 0 0 39 APOE 7.13 351 1,543 40 L3MBTL4-AS1 7.12 0 0 41 DNASE2B 7.09 0 0 42 MSR1 7.07 12 12 43 MMP19 7.02 0 0 44 SPI1 7.01 — — 45 SPOCD1 6.99 4 5 46 VSIG4 6.98 — — 47 CEP55 6.95 0 0 48 FOLR2 6.87 11 11 49 FABP5 6.85 2 0 50 COL4A2-AS2 6.80 21 44 51 APOBEC3B 6.79 3 3 52 CCL18 6.72 10 10 53 MS4A5 6.71 69 99 54 HPGDS 6.70 11 34 55 CDC20 6.65 4 7 56 MNDA 6.61 3 16 57 TROAP 6.59 0 1 58 CCL3 6.56 9 13 59 DLGAP5 6.55 4 27 60 CCNB2 6.55 15 22 61 CCL22 6.54 2 5 62 HAMP 6.53 11 38 63 MMP7 6.52 4 9 64 CD36 6.50 101 134 65 AURKB 6.43 0 0 66 SDS 6.39 7 11 67 DHRS9 6.38 21 60 68 CKAP2L 6.38 6 23 69 LINC01827 6.37 4 7 70 CLSPN 6.37 1 2 71 FAM111B 6.36 0 0 72 MS4A14 6.33 79 127 73 MS4A7 6.32 79 121 74 CDKN3 6.30 0 0 75 SPINK6 6.30 2 2 76 RNASE1 6.30 4 4 77 CENPF 6.29 0 1 78 FBP1 6.27 15 36 79 LILRB4 6.22 14 16 80 APOC2 6.19 203 1,252 81 CCL7 6.13 2 11 82 MELK 6.13 0 0 83 NUSAP1 6.13 1 3 84 PLK1 6.09 0 0 85 ASPM 6.09 23 49 86 LINC02243 6.07 — — 87 CDC45 6.07 1 1 88 DEPDC1 6.06 0 0 89 NCAPH 6.06 — — 90 PIMREG 6.06 0 0 91 ACP5 6.04 6 8 92 HMMR 6.04 0 0 93 CENPM 6.04 29 65 94 ZWINT 6.03 0 0 95 HJURP 6.02 29 41 96 LINC01010 6.01 1 0 97 OR8G5 6.01 0 0 98 CCL24 6.00 9 31 99 LINC02375 5.99 — — 100 GAPLINC 5.98 0 0 101 GAL 5.98 6 12 102 RAD51 5.98 7 7 103 ESCO2 5.98 5 8 104 OCSTAMP 5.97 1 1 105 TPX2 5.95 — — 106 LINC02345 5.90 3 10 107 HLA-DRA 5.90 693 1,237 108 SPC24 5.89 93 836 109 MMP12 5.86 2 2 110 C15orf48 5.86 5 28 111 MS4A6A 5.85 38 78 112 RAB7B 5.84 3 5 113 KIF4A 5.83 — — 114 SHCBP1 5.82 0 0 115 NCAPG 5.82 1 1 116 DIAPH3 5.79 1 1 117 CDCA5 5.73 3 4 118 CENPU 5.72 9 17 119 CAPG 5.71 33 98 120 SYCE2 5.70 3 3 121 CENPW 5.70 17 39 122 RAD51AP1 5.69 2 2 123 LINC02209 5.68 — — 124 SLAMF8 5.68 12 16 125 MMP8 5.68 4 4 126 CD163 5.61 0 0 127 TOP2A 5.59 20 58 128 MND1 5.59 1 3 129 CRYBB1 5.59 0 0 130 SKA3 5.58 0 0 131 SIGLEC15 5.51 1 13 132 ARHGEF39 5.51 17 49 133 GPNMB 5.50 2 6 134 MTFR2 5.50 0 0 135 STMN1 5.48 0 0 136 PLAUR 5.48 34 60 137 CXCL3 5.47 4 8 138 KIF2C 5.45 0 0 139 TRIP13 5.45 1 1 140 SGO1 5.43 0 0 141 ASF1B 5.43 6 35 142 KIFC1 5.42 1 1 143 MRC1 5.42 5 7 144 CXCL16 5.42 19 69 145 CDCA8 5.42 1 5 146 AIF1 5.40 433 801 147 HLA-DRB1 5.39 565 1,192 148 KIF23 5.39 0 0 149 MEIKIN 5.34 7 26 150 RARRES1 5.34 2 7 151 MIR3945HG 5.34 12 29 152 CST3 5.32 — — 153 LINC02321 5.30 0 0 154 UHRF1 5.29 12 30 155 LINC00504 5.28 2 3 156 CDT1 5.27 4 11 157 PBK 5.26 10 14 158 ETV5-AS1 5.26 — — 159 BUB1B 5.26 5 15 160 SKA1 5.25 0 0 161 LGALS3 5.25 7 33 162 FIGLA 5.24 0 0 163 DEPDC1-AS1 5.24 0 0 164 E2F8 5.23 0 0 165 MCM10 5.22 0 0 166 S100A9 5.21 4 15 167 NDC80 5.20 0 0 168 PTTG1 5.20 0 0 169 OIP5 5.19 0 0 170 MYOZ1 5.19 13 97 171 ANKRD66 5.16 0 0 172 OLR1 5.15 3 4 173 TNNI2 5.14 29 80 174 CD52 5.14 10 50 175 BCL2A1 5.12 36 82 176 C5AR1 5.11 4 9 177 MARCO 5.10 13 17 178 GPR34 5.09 — — 179 SLC7A13 5.08 0 0 180 MYBL2 5.08 10 32 181 IQGAP3 5.08 34 104 182 LINC01740 5.07 12 36 183 KNL1 5.07 7 7 184 CTSL 5.06 2 3 185 IL10 5.06 18 25 186 RNASE6 5.05 6 6 187 FAM187B 5.04 72 141 188 RGCC 5.04 1 4 189 GSG1 4.99 0 3 190 CD33 4.99 18 76 191 GINS2 4.99 1 5 192 LPL 4.98 50 219 193 LINC02154 4.96 — — 194 CDC25C 4.96 0 0 195 FTL 4.95 5 6 196 POC1A 4.93 72 153 197 NUF2 4.93 0 0 198 CSTB 4.91 0 0 199 FPR3 4.91 41 55 200 BUB1B-PAK6 4.91 — — 201 POLQ 4.90 20 48 202 CTSB 4.90 127 493 203 FOXM1 4.89 1 2 204 NEIL3 4.89 0 0 205 LY86 4.89 12 21 206 RAB42 4.89 3 2 207 CCRL2 4.89 28 59 208 PLEK 4.88 27 52 209 LINC01150 4.87 5 19 210 LST1 4.87 183 440 211 CDCA2 4.83 8 16 212 SMC1B 4.81 6 10 213 CCNB1 4.81 4 3 214 DEFB126 4.80 — — 215 NEK2 4.80 9 21 216 LINC00520 4.80 0 0 217 NCF2 4.79 30 57 218 GCM1 4.79 5 26 219 SPATA12 4.77 3 3 220 HMGB3 4.76 — — 221 EXO1 4.75 0 0 222 KIF20A 4.75 0 0 223 CTSD 4.73 14 22 224 CSF1R 4.72 19 43 225 VMO1 4.71 23 76 226 IL1B 4.70 15 58 227 ANLN 4.70 1 3 228 GPC4 4.70 — — 229 KIF15 4.70 0 0 230 CSTA 4.69 16 57 231 LINC02201 4.66 3 6 232 CD86 4.66 14 44 233 LRRC25 4.65 40 79 234 SUCNR1 4.64 1 4 235 DHFR 4.60 0 0 236 GPR84 4.59 141 177 237 KRT79 4.59 18 28 238 PRC1 4.59 1 2 239 CCL4L2 4.59 2 1 240 TFEC 4.59 9 81 241 CYBB 4.58 — — 242 HLA-DQA1 4.58 608 1,232 243 HCST 4.58 0 0 244 FCGR2B 4.58 209 293 245 ADORA3 4.57 2 3 246 HMOX1 4.57 2 1 247 LGALS1 4.56 22 66 248 MATK 4.54 0 0 249 E2F7 4.53 0 0 250 CEACAM8 4.53 5 5 251 HCK 4.51 16 41 252 AURKA 4.51 2 8 253 MAD2L1 4.50 2 2 254 KIF18B 4.50 0 0 255 CD74 4.48 13 14 256 HLA-DPA1 4.47 287 545 257 KIF14 4.47 0 1 258 TCF19 4.46 196 428 259 DEPDC1B 4.46 0 0 260 FAM72D 4.46 — — 261 TIMD4 4.45 43 337 262 CCL4 4.44 11 15 263 BUB1 4.43 4 9 264 TMEM89 4.42 — — 265 CD300C 4.42 14 41 266 ST3GAL6-AS1 4.41 32 48 267 CD5L 4.41 14 14 268 GCM2 4.41 — — 269 HLA-DRB5 4.40 364 756 270 SDSL 4.39 7 11 271 FCGR2A 4.39 192 263 272 CLEC7A 4.38 7 9 273 CDCP1 4.37 5 5 274 RAD54L 4.37 6 12 275 LGALS9 4.37 — — 276 ADAP2 4.36 — — 277 S100A8 4.36 10 20 278 CYP27A1 4.35 43 170 279 FBXO43 4.35 0 0 280 FCGR1A 4.34 0 0 281 KLK4 4.33 1 2 282 RAB31 4.33 2 5 283 UBE2T 4.33 0 0 284 ASPHD1 4.32 2 2 285 CLEC4A 4.32 1 1 286 CXCL8 4.31 2 6 287 C1orf162 4.30 1 3 288 NPC2 4.30 1 6 289 SNCA 4.30 7 8 290 OR13A1 4.30 0 29 291 LILRB3 4.29 88 146 292 LRP1-AS 4.29 25 147 293 TNFRSF11A 4.29 2 4 294 S100A11 4.28 3 3 295 IL18 4.28 4 3 296 GGH 4.26 8 10 297 ORC6 4.24 0 0 298 VIM 4.24 32 102 299 HLA-DQB1 4.23 703 1,314 300 CD14 4.23 22 52 301 TUBB6 4.23 3 4 302 CD207 4.22 1 1 303 LGMN 4.21 6 6 304 LGALS2 4.20 11 25 305 C1orf54 4.20 7 10 306 ZDHHC19 4.19 14 21 307 SLC11A1 4.19 29 146 308 LILRB5 4.18 96 158 309 RAB13 4.18 8 20 310 NPL 4.18 5 5 311 NRGN 4.17 0 0 312 ITGB2 4.17 45 135 313 KIF11 4.17 0 3 314 CD9 4.17 2 6 315 CD300LB 4.17 15 41 316 SLC7A7 4.16 22 46 317 GGTLC3 4.16 6 7 318 NRIP3 4.16 0 0 319 PLEK2 4.14 0 0 320 HSD3B7 4.13 46 104 321 MYBPH 4.12 4 7 322 PAQR5 4.11 0 0 323 SLC15A3 4.11 15 59 324 PVALB 4.11 9 24 325 ATP6V0D2 4.10 1 1 326 SAGE1 4.10 — — 327 MCEMP1 4.10 15 16 328 LINC02099 4.10 0 0 329 FABP3 4.09 11 20 330 CPVL 4.08 3 3 331 GEM 4.08 7 10 332 RAB20 4.08 13 21 333 ARHGAP11A 4.08 0 0 334 KYNU 4.07 8 10 335 CD83 4.07 6 7 336 CENPE 4.07 2 1 337 G0S2 4.07 8 30 338 HK3 4.07 3 4 339 LSP1 4.07 41 132 340 LAPTM5 4.07 16 38 341 FGR 4.06 8 26 342 OSCAR 4.06 6 6 343 SDC2 4.06 1 3 344 LINC02294 4.05 0 0 345 CXCL2 4.05 12 42 346 E2F1 4.04 5 7 347 DAB2 4.04 39 81 348 HSPA6 4.02 198 266 349 SPACA4 4.02 — — 350 SRGN 4.01 34 60 351 MGLL 4.01 16 18 352 LILRB2 4.00 89 145 353 KRTAP19-1 4.00 — — 354 HLA-DMB 4.00 224 330 355 ZNF385A 3.99 94 96 356 C3AR1 3.99 4 4 357 TAB2-AS1 3.99 0 0 358 NCF4 3.98 7 38 359 TUBA1B 3.98 0 0 360 SCIN 3.95 0 0 361 LY96 3.95 3 3 362 CKS2 3.94 0 0 363 ACTBL2 3.94 0 0 364 GPR183 3.94 11 28 365 TMIGD3 3.94 3 3 366 SLC12A5 3.93 15 97 367 ZMYND10 3.93 3 10 368 TMEM37 3.93 6 11 369 CD1C 3.91 2 13 370 GRN 3.91 12 23 371 CCL2 3.90 3 12 372 LINC00911 3.90 0 0 373 MT1G 3.88 28 174 374 CENPN 3.88 0 0 375 LINC02507 3.88 — — 376 ZGLP1 3.87 11 32 377 LINC01857 3.87 0 0 378 TIMP3 3.86 3 3 379 CDH23 3.86 40 78 380 SPAG5 3.85 — — 381 CLEC11A 3.85 0 0 382 MILR1 3.85 18 52 383 CTSH 3.85 26 31 384 CTSZ 3.84 8 56 385 PLBD1 3.84 4 7 386 LAIR1 3.83 55 110 387 SIGLEC9 3.82 16 30 388 HLA-DMA 3.82 226 330 389 GAS2L3 3.82 9 17 390 SELENOP 3.81 3 4 391 PMFBP1 3.80 105 226 392 LINC01526 3.80 0 0 393 MAFB 3.79 4 11 394 CR1L 3.79 23 45 395 FCER1A 3.79 34 50 396 TM6SF1 3.78 5 10 397 CFD 3.78 32 76 398 ZMIZ1-AS1 3.78 6 18 399 CCL13 3.78 2 11 400 CENPK 3.78 0 0 401 LILRA2 3.77 14 17 402 ITGAX 3.77 52 132 403 DIAPH2-AS1 3.77 — — 404 SYK 3.76 5 24 405 TMEM52B 3.76 4 4 406 ECM1 3.76 60 158 407 WNT1 3.76 4 7 408 ABCG2 3.76 18 43 409 CTSV 3.76 0 0 410 HNMT 3.76 2 2 411 SAC3D1 3.75 2 4 412 OR2C3 3.75 4 14 413 CCL23 3.73 9 8 414 TPSB2 3.73 0 0 415 UBTD1 3.72 4 15 416 GM2A 3.70 17 39 417 FAM72C 3.70 — — 418 ESPL1 3.70 0 0 419 FCN1 3.70 5 6 420 S100A4 3.70 2 2 421 TIFAB 3.69 2 4 422 ARL14EPL 3.69 1 2 423 GPX1 3.69 53 128 424 GLIPR2 3.68 2 2 425 IL36RN 3.67 16 44 426 CARD9 3.67 51 204 427 HLA-DPB1 3.66 293 562 428 MITF 3.66 3 5 429 RAB32 3.66 2 1 430 BLVRB 3.65 12 44 431 CATSPER1 3.65 16 32 432 MT1H 3.65 36 222 433 CCNE1 3.65 0 1 434 RIBC2 3.64 6 10 435 SH3BGRL3 3.63 18 62 436 HAAO 3.62 16 23 437 TMEM114 3.62 0 0 438 PLTP 3.62 18 36 439 SIGLEC7 3.62 1 1 440 RGS1 3.61 7 12 441 TACR2 3.61 19 35 442 MUC12 3.60 14 29 443 ROR1-AS1 3.60 1 3 444 GLIPR1 3.59 0 1 445 AQP9 3.59 44 363 446 DTL 3.58 13 43 447 DTYMK 3.58 0 0 448 FCGR3A 3.58 184 260 449 BTK 3.57 — — 450 ST14 3.57 2 2 451 GNA15 3.57 9 20 452 TICRR 3.57 1 1 453 LAT2 3.56 34 78 454 NRP2 3.56 6 5 455 HAPLN4 3.56 30 97 456 UCP2 3.55 1 1 457 CHEK1 3.54 1 1 458 CLEC10A 3.54 20 20 459 FCGRT 3.54 65 213 460 CENPS-CORT 3.54 4 10 461 TUBB 3.54 165 310 462 FFAR4 3.54 2 2 463 BRCA2 3.52 4 6 464 LINC01537 3.52 1 1 465 COTL1 3.52 17 66 466 TMEM106C 3.52 3 4 467 CENPS 3.52 4 10 468 FTH1 3.51 12 170 469 CDKN2A 3.51 3 4 470 HELLS 3.50 4 6 471 FEN1 3.49 40 105 472 CCDC34 3.49 0 0 473 ADAMDEC1 3.49 2 2 474 LKAAEAR1 3.49 21 61 475 KMO 3.48 0 0 476 GPR33 3.48 0 0 477 SLC37A2 3.48 5 5 478 SGO2 3.48 0 0 479 S100A6 3.47 3 4 480 MRAS 3.47 11 29 481 MXD3 3.47 29 73 482 C19orf38 3.46 0 1 483 CTSS 3.46 129 340 484 KCNMB1 3.45 2 6 485 TMEM266 3.45 5 7 486 RDH12 3.44 0 0 487 CD163L1 3.44 0 0 488 ACOD1 3.43 0 0 489 MMP2-AS1 3.43 4 7 490 VAV3-AS1 3.43 1 4 491 A2M 3.43 — — 492 PRR11 3.42 0 0 493 IL1A 3.42 6 22 494 CCL20 3.41 4 4 495 ALDH3B1 3.41 4 10 496 RPL39L 3.41 2 2 497 CD1E 3.41 8 21 498 CCDC88A 3.40 3 11 499 PRAM1 3.40 84 448 500 DHDH 3.40 20 30 501 GDF15 3.40 43 83 502 CKS1B 3.40 5 10 503 LINC00656 3.39 — — 504 ANXA2 3.39 8 11 505 ADORA2B 3.39 7 17 506 ACTL7B 3.38 — — 507 LINC00900 3.38 1 1 508 PSMC3IP 3.38 1 1 509 TGFBI 3.38 9 12 510 ACOT7 3.37 7 165 511 MGST1 3.37 2 1 512 CENPI 3.37 — — 513 BST1 3.37 2 2 514 CRIP1 3.36 2 11 515 TTK 3.36 0 0 516 RAC2 3.36 7 38 517 PTAFR 3.35 2 2 518 LINC00589 3.35 0 0 519 ABHD16B 3.35 — — 520 VAMP8 3.35 38 110 521 PILRA 3.34 28 67 522 HCAR2 3.34 3 15 523 ALCAM 3.34 1 1 524 BRIP1 3.33 0 0 525 SRD5A3 3.33 3 13 526 TREM1 3.33 1 8 527 PAPSS2 3.32 1 2 528 ARPC1B 3.32 27 109 529 LINC02542 3.31 0 0 530 FAM72B 3.31 7 8 531 DBI 3.31 5 10 532 PIF1 3.30 109 146 533 PKIB 3.30 1 1 534 CDC6 3.29 12 41 535 SLC22A16 3.29 0 0 536 PTMS 3.29 15 37 537 KCNN4 3.29 27 66 538 LIPA 3.29 13 35 539 RETN 3.28 14 15 540 NLRC4 3.28 4 8 541 BCAT1 3.28 3 3 542 TUBA1C 3.28 0 0 543 SNRNP25 3.27 1 2 544 CD1B 3.27 6 6 545 LINC02564 3.27 3 3 546 ACOT1 3.27 0 0 547 AVPI1 3.27 2 5 548 SMC2 3.26 6 10 549 KCNJ5 3.26 38 44 550 LINC01077 3.26 1 2 551 CLDN5 3.26 2 1 552 RNASE2 3.26 0 0 553 CA2 3.25 3 3 554 RMI2 3.25 9 16 555 CD300LF 3.25 14 59 556 CD84 3.24 16 23 557 TMEM51 3.24 5 14 558 MCTP1 3.24 1 1 559 SLCO2B1 3.23 1 1 560 CCR1 3.23 11 25 561 EZH2 3.23 0 0 562 PLD4 3.23 2 1 563 NFAM1 3.22 5 5 564 ASRGL1 3.22 13 40 565 HS3ST1 3.22 1 2 566 AP2S1 3.20 25 37 567 OR6N1 3.20 — — 568 RECQL4 3.20 0 0 569 CD109 3.20 0 0 570 TNFSF13B 3.20 1 0 571 SIRPB1 3.19 19 63 572 MREG 3.19 1 2 573 ATP6V1G3 3.19 12 71 574 FDX1 3.18 1 1 575 SMCO4 3.18 0 1 576 CBR3 3.18 1 5 577 PCNA 3.17 1 0 578 OTOA 3.17 2 3 579 LCP1 3.16 7 9 580 ARL11 3.16 1 0 581 PARPBP 3.15 0 0 582 PGA5 3.14 17 73 583 EIF4EBP1 3.14 0 0 584 EBI3 3.14 4 8 585 NRM 3.14 153 292 586 SLC1A3 3.14 0 0 587 CRABP2 3.14 3 4 588 CD276 3.14 13 27 589 RBP7 3.13 3 8 590 ANKRD34C-AS1 3.13 0 0 591 PLK4 3.13 0 0 592 TPSAB1 3.12 1 3 593 SPHK1 3.12 1 6 594 AREG 3.12 2 6 595 RBM47 3.12 10 13 596 WFDC10A 3.12 0 0 597 SLC31A2 3.11 7 16 598 CLIC1 3.11 159 256 599 RDM1 3.11 7 8 600 CCDC63 3.11 4 5 601 PHLDA1 3.10 0 1 602 RNASEH2A 3.10 0 0 603 SLC16A3 3.10 15 37 604 EMP1 3.10 5 13 605 CD180 3.10 1 6 606 ZMYND15 3.10 30 103 607 GINS1 3.10 0 0 608 MPP1 3.09 — — 609 STX11 3.09 1 2 610 ATAD2 3.09 0 0 611 TNFAIP8L2 3.09 11 38 612 AUNIP 3.08 2 2 613 PTPRO 3.08 4 8 614 ERCC6L 3.08 — — 615 ZDHHC12 3.07 11 25 616 TUBG1 3.07 0 0 617 DUSP2 3.07 — — 618 LINC01637 3.06 2 5 619 CHST13 3.06 12 26 620 LINC00865 3.06 0 0 621 HPGD 3.06 0 0 622 TMEM132E 3.06 1 1 623 CALM3 3.06 6 12 624 PDYN-AS1 3.05 12 47 625 ANXA1 3.05 2 2 626 LINC01095 3.04 0 0 627 PRRG4 3.03 3 4 628 PAQR4 3.03 0 0 629 SBF2-AS1 3.03 14 69 630 PYCARD 3.03 3 3 631 CD302 3.02 13 43 632 LINC00604 3.02 0 1 633 ATP6V1F 3.02 14 34 634 DOK2 3.02 20 88 635 CLEC12A 3.01 41 41 636 NUDT1 3.01 4 6 637 TMEM176B 3.01 39 71 638 GCHFR 3.01 9 9 639 CSF3R 3.01 14 53 640 FERMT3 3.00 17 63 641 CENPH 3.00 4 3 642 CAVIN3 3.00 0 0 643 ATP8B4 2.99 7 22 644 SMIM10 2.99 — — 645 TPSD1 2.99 0 1 646 CAMK1 2.98 0 0 647 CCNE2 2.98 6 26 648 NCAPG2 2.97 8 12 649 PHF19 2.96 11 32 650 NR1H3 2.96 — — 651 PLAU 2.96 21 55 652 ARHGAP18 2.95 0 0 653 MIR155HG 2.95 0 0 654 CPM 2.95 1 1 655 CENPA 2.95 4 16 656 RACGAP1 2.95 1 1 657 HMGN2 2.94 0 0 658 SLC8A1 2.94 3 46 659 LINC01645 2.94 1 2 660 WDFY4 2.94 4 4 661 GSN 2.94 10 25 662 LINC02285 2.94 0 3 663 IL18BP 2.93 2 1 664 GALM 2.93 1 10 665 CD63 2.93 0 0 666 GSTO1 2.92 1 8 667 CYTL1 2.92 0 1 668 CCL17 2.91 3 7 669 MNS1 2.91 0 0 670 EMILIN2 2.91 13 23 671 KNSTRN 2.91 4 14 672 RAB34 2.91 — — 673 MME-AS1 2.91 0 0 674 TIMP2 2.91 2 3 675 RGS10 2.91 8 23 676 KIF24 2.90 0 0 677 NAGA 2.90 16 35 678 DRAM1 2.90 33 37 679 CLDN23 2.89 63 269 680 TRAIP 2.89 10 10 681 CENPP 2.89 26 56 682 SHTN1 2.89 6 9 683 CD300A 2.89 16 40 684 PPARG 2.88 122 460 685 TSPAN4 2.88 20 57 686 LMNA 2.87 18 37 687 WDR76 2.87 4 5 688 STUM 2.87 2 3 689 EREG 2.87 12 26 690 ANXA5 2.86 4 7 691 LILRA5 2.86 85 139 692 CXCL5 2.85 1 1 693 GAPT 2.85 0 0 694 HBEGF 2.84 22 47 695 FANCI 2.84 10 26 696 CKAP2 2.84 1 4 697 CACNA2D4 2.83 2 3 698 PLD3 2.83 7 17 699 CD53 2.83 9 18 700 LILRB1 2.83 17 21 701 CST6 2.83 10 22 702 AGRP 2.83 11 17 703 WDR62 2.82 3 8 704 GMNN 2.82 5 6 705 OTUB2 2.81 328 449 706 FAM72A 2.81 5 7 707 M1AP 2.81 0 0 708 SLC29A3 2.81 26 41 709 POLE2 2.81 1 1 710 RRAGD 2.81 2 2 711 PARVB 2.80 35 46 712 LYVE1 2.80 5 10 713 IMPA2 2.80 6 13 714 GPR85 2.79 0 0 715 MCM2 2.79 8 10 716 TSPAN33 2.79 3 8 717 HS3ST2 2.79 — — 718 CLEC4C 2.78 — — 719 PARVG 2.78 2 1 720 SLC2A9 2.78 11 26 721 KCNH4 2.78 18 49 722 TMSB4X 2.77 — — 723 SIRPA 2.77 4 7 724 CDKN2C 2.77 0 0 725 S100A10 2.77 5 10 726 PLIN2 2.76 4 7 727 S100B 2.76 19 57 728 CD80 2.76 2 4 729 ITGAM 2.76 46 92 730 GLA 2.76 — — 731 LINC01925 2.76 12 19 732 RPP25 2.76 4 10 733 ATP6V0C 2.75 2 6 734 ORC1 2.75 0 0 735 TSPO 2.75 13 39 736 ARRB2 2.74 14 58 737 CCL8 2.74 5 14 738 IBSP 2.74 7 16 739 FCER2 2.73 15 16 740 KCNK13 2.73 0 0 741 SLC1A4 2.73 48 177 742 SIGLEC1 2.73 22 44 743 SMS 2.73 — — 744 OR6A2 2.72 — — 745 EGFL7 2.72 10 21 746 RENBP 2.72 — — 747 MGST2 2.72 0 0 748 ERICH4 2.72 0 0 749 OAZ3 2.71 0 0 750 TRPM2 2.71 34 103 751 MCM4 2.71 0 0 752 OSM 2.71 19 68 753 TMEM53 2.71 0 0 754 CLEC5A 2.71 2 2 755 CCNA1 2.71 0 0 756 STAB1 2.70 120 362 757 LSM4 2.70 33 62 758 FFAR2 2.70 1 1 759 SLC2A5 2.70 3 7 760 GNG5 2.70 2 2 761 TMEM176A 2.70 50 102 762 LRMDA 2.69 13 14 763 RPA3 2.69 0 0 764 FAIM 2.69 2 2 765 RHEB 2.68 4 7 766 LINC02185 2.68 0 0 767 TUBA8 2.68 7 8 768 ARHGAP40 2.68 0 0 769 FAAP24 2.67 22 60 770 RGS18 2.67 0 0 771 RNF130 2.67 7 10 772 TNFSF15 2.67 37 62 773 ARHGAP11B 2.66 0 0 774 DCAF4L1 2.66 0 0 775 KPNA2 2.66 2 4 776 HMGA1 2.66 15 37 777 PKDREJ 2.65 0 0 778 ARHGDIB 2.65 3 8 779 PCBD1 2.65 4 4 780 FADS1 2.65 63 361 781 SLC25A5 2.65 — — 782 CCDC170 2.65 10 17 783 SERPINA1 2.64 359 511 784 EME1 2.64 2 2 785 CYBA 2.64 28 69 786 P2RY11 2.64 0 0 787 ETV3L 2.63 3 6 788 LXN 2.63 0 0 789 SCIMP 2.63 26 40 790 SGK1 2.62 2 1 791 CDCA7 2.62 1 3 792 TP73 2.62 2 2 793 AWAT2 2.62 — — 794 MS4A4E 2.62 63 119 795 IRF8 2.62 30 75 796 BARD1 2.62 6 15 797 SNX8 2.62 4 6 798 FLT3 2.62 6 18 799 NPM3 2.61 0 0 800 RAB39A 2.61 0 0 801 IL37 2.61 5 18 802 RBP4 2.60 21 82 803 MYO7A 2.60 2 6 804 XRCC2 2.60 1 1 805 FBXO5 2.59 0 1 806 ABRACL 2.59 5 13 807 IRF5 2.58 48 98 808 SLC43A3 2.58 27 87 809 TBXAS1 2.58 5 10 810 AGPAT2 2.57 7 22 811 IGFLR1 2.57 1 1 812 LINC01503 2.57 1 1 813 PPIF 2.56 40 112 814 IFI27 2.56 332 479 815 CENPX 2.56 0 0 816 NT5DC2 2.56 72 152 817 SPINT1 2.56 13 15 818 FPR1 2.56 44 63 819 OPN1LW 2.56 — — 820 MELTF 2.56 0 1 821 IGSF21 2.55 0 0 822 ATF3 2.55 8 26 823 CYSTM1 2.55 11 14 824 SLC25A19 2.55 15 41 825 CYP2S1 2.55 7 10 826 SEL1L2 2.55 0 0 827 EP300-AS1 2.54 4 11 828 CD22 2.54 75 137 829 C10orf55 2.54 6 20 830 LMNB1 2.54 2 5 831 LINC01629 2.54 3 4 832 TMEM121B 2.54 — — 833 GINS4 2.54 2 1 834 KIF20B 2.54 2 2 835 CHAF1A 2.54 12 38 836 YBX1 2.54 0 0 837 LINC01954 2.53 0 1 838 CXCL10 2.53 8 10 839 ANAPC11 2.53 1 0 840 CIT 2.53 0 0 841 MTHFD2 2.52 2 1 842 SPARC 2.52 1 2 843 PDE6G 2.52 1 1 844 RGS2 2.52 0 0 845 ECT2 2.52 7 9 846 C21orf58 2.52 23 61 847 LIMS1-AS1 2.52 — — 848 LILRA6 2.51 85 140 849 ATP1B1 2.51 13 155 850 ARHGAP22 2.51 5 5 851 TCHH 2.50 0 0 852 GNB4 2.50 2 6 853 CD209 2.50 9 13 854 FAM111A 2.50 1 6 855 DHRS11 2.50 8 15 856 TRPV2 2.50 15 42 857 MT2A 2.50 10 12 858 FAM20A 2.50 34 62 859 BID 2.50 10 10 860 ELAVL4 2.50 0 0 861 LINC01054 2.50 2 2 862 SERPINE1 2.49 25 41 863 NETO2 2.49 1 1 864 CD1D 2.49 7 19 865 HDAC2-AS2 2.49 0 0 866 ATAD5 2.49 — — 867 KCNMA1 2.48 4 4 868 MGST3 2.48 0 0 869 ALOX15B 2.48 18 31 870 TIMELESS 2.48 1 4 871 MSLN 2.48 1 1 872 MYL9 2.48 7 17 873 NPHS1 2.48 2 2 874 LRR1 2.48 1 1 875 MME 2.48 2 2 876 S100A5 2.47 0 0 877 CST2 2.47 — — 878 DSCC1 2.47 7 12 879 SIRPB2 2.47 11 17 880 B3GNT5 2.47 0 0 881 SNX10 2.47 33 87 882 ANPEP 2.47 13 24 883 LPCAT2 2.47 3 6 884 FXYD5 2.47 87 178 885 MCM5 2.46 3 9 886 ATP6V0B 2.46 2 4 887 CYTOR 2.46 2 2 888 BHLHE41 2.46 16 23 889 SLC22A6 2.45 0 0 890 TMEM26-AS1 2.45 16 15 891 TCEAL9 2.45 — — 892 OR10A4 2.45 — — 893 KLK1 2.45 3 7 894 SLC38A6 2.45 0 0 895 STIL 2.44 10 12 896 TSPAN15 2.44 35 53 897 NENF 2.44 14 43 898 SLC5A12 2.44 0 0 899 ENG 2.44 9 25 900 KRT78 2.44 18 28 901 ITGAD 2.44 19 36 902 FKBP1A 2.43 5 6 903 SIGLEC12 2.43 24 34 904 FAH 2.43 6 14 905 FN1 2.43 29 100 906 CKLF-CMTM1 2.43 14 14 907 ABCC5-AS1 2.43 10 16 908 OR9Q1 2.43 13 45 909 TMEM255B 2.43 7 29 910 RASSF4 2.43 1 0 911 E2F2 2.43 8 74 912 PLPP4 2.43 0 0 913 GFRA2 2.43 11 37 914 C5AR2 2.42 3 5 915 GNGT2 2.42 34 141 916 ST18 2.42 0 0 917 NRP1 2.42 9 18 918 PTGS1 2.41 0 0 919 FADS2 2.41 64 209 920 CKLF 2.41 7 8 921 CLEC4E 2.41 — — 922 TCN2 2.41 10 26 923 SPR 2.41 0 0 924 PFN1 2.41 6 35 925 CHAF1B 2.41 0 1 926 MIR4435-2HG 2.41 13 33 927 COPRS 2.41 — — 928 SLC39A8 2.41 55 116 929 KCNAB2 2.41 7 165 930 CEACAM3 2.41 0 0 931 C7orf57 2.40 0 0 932 F13A1 2.40 5 8 933 BASP1 2.40 0 0 934 MARCKS 2.40 1 2 935 INHBA 2.40 0 1 936 CNRIP1 2.40 26 38 937 COX8A 2.40 0 0 938 XKR3 2.40 — — 939 SIGLEC11 2.40 7 13 940 ABI3 2.40 42 147 941 ETV5 2.39 86 207 942 EFCAB11 2.39 0 0 943 FLNC-AS1 2.39 13 33 944 TUBB3 2.39 13 31 945 GINS3 2.39 0 1 946 LINC01094 2.38 0 3 947 TNFSF13 2.38 27 53 948 QPCT 2.38 2 11 949 CENPO 2.38 14 40 950 ZNF695 2.38 2 4 951 LINC02550 2.37 0 0 952 ARHGAP6 2.37 — — 953 JPT1 2.37 10 22 954 CAMK2B 2.37 8 16 955 LINC02139 2.37 3 7 956 IGSF22 2.37 1 1 957 PSRC1 2.36 4 5 958 TIMM10 2.36 25 73 959 IFI6 2.36 3 6 960 SLC25A10 2.36 10 26 961 PLB1 2.36 19 42 962 GMFG 2.35 1 1 963 DNA2 2.35 1 3 964 SMC4 2.35 0 0 965 GYPC 2.35 3 4 966 ABCB5 2.35 3 4 967 FANCD2OS 2.35 0 0 968 HLA-DQA2 2.35 173 495 969 GNG11 2.35 3 3 970 KCTD19 2.34 21 48 971 BATF3 2.34 5 4 972 TMEM14C 2.34 0 0 973 GPX3 2.34 9 17 974 DERL3 2.34 8 33 975 ZYX 2.33 6 10 976 FUCA2 2.33 6 7 977 PRDX1 2.32 1 2 978 LIPN 2.32 1 1 979 SOWAHD 2.32 — — 980 FANCG 2.32 0 0 981 FUOM 2.31 5 5 982 SKA2 2.31 0 0 983 NEK6 2.31 13 25 984 FAM83D 2.30 1 0 985 ATOX1 2.30 1 4 986 HEXB 2.30 0 0 987 TPRG1-AS1 2.30 4 5 988 CATIP 2.30 37 147 989 LINC02124 2.30 1 0 990 CFL1 2.30 24 101 991 PAFAH1B3 2.29 0 0 992 CLN6 2.29 0 1 993 GPAT3 2.29 1 1 994 MASTL 2.29 0 0 995 IL13RA1 2.29 — — 996 IL1R2 2.29 24 43 997 PRADC1 2.28 1 2 998 PLP2 2.28 — — 999 LINC00664 2.28 0 0 1000 OLFML2B 2.28 9 18