Evidence reports Cell populations IPSC.mesodermal_primed DE genes Static evidence for AI interpretation. These reports provide data for prompting AI and are not intended as a human-facing reading interface. Please visit the Cell Browser , Trait Browser and Genome Browser for interactive browsing. Have fun exploring SCREATE!Association counts use unique genes with 01-High Priority evidence and unique cells in the authored Specific tier (not the IC-score significance threshold). Reverse counts list meta traits and individual traits separately; these are overlapping levels of evidence, not independent totals. Counts cover the full available catalogue, not the displayed rows or sampled UMAP. Unavailable profiles are excluded from reverse counts; a dash means unavailable or an ambiguous identity, not zero. The browser initially shows 50 rows; choose Rows to change this. Complete rows remain in the HTML, and ordinary page links expose any continuation pages for AI readers and crawlers.
IPSC.mesodermal_primed: DE genes
How association tiers are defined — cell–trait and gene–trait SCREATE tier definitions supplied by the atlas curator. This methods note explains the prepared classifications; it does not recompute or change any report scores or tiers.
Cell–trait tiers Cell–trait links Identify cell types whose regulatory activity is associated with a trait’s genetic signal. Required for Specific or Relevant The ICE-CREAM score derived from the mean metacell Z score must be ≥ 5.39, with BOTH nominal and adjusted ICE-CREAM P values ≤ 0.05. Specific (Tier 1) Also meets all cell-set enrichment analysis (CSEA) criteria in at least one tested comparison: nominal P ≤ 0.05 AND adjusted P ≤ 0.05 AND normalized enrichment score (NES) ≥ 1, all in that comparison. This indicates that trait-associated activity is concentrated in this cell type relative to the tested background. Relevant (Tier 2) Meets the ICE-CREAM requirements but not the additional CSEA criteria. The cell type may share trait-associated activity with other cell types. Interpretation and report values CSEA is cell-set enrichment analysis, analogous to gene-set enrichment analysis but using sets of cells along a ranked list of ICE-CREAM scores. The eligibility score derived from the mean metacell Z score is not the displayed mean IC score. Do not infer a tier from the displayed mean, its descriptive Significance column, or a single CSEA summary value. Reports preserve prepared tiers; Other means an available association outside Specific/Relevant, and unavailable is not zero or proof of biological irrelevance. Meta traits and individual traits Use the prepared tier for the exact meta trait or individual trait. A meta trait’s Best child CSEA FDR is the lowest available child FDR, not a combined or meta-trait significance test. Its displayed mean child NES is descriptive, not a new CSEA test. These summaries must not be used to reconstruct or override the meta-trait tier. Gene–trait priorities (variant–tCRE–gene evidence) Variant–tCRE–gene links Candidate variants connect to genes through overlapping promoters or distal transcribed cis-regulatory elements (tCREs) linked to gene promoters by the Activity-by-Contact (ABC) model. Required genetic support The variant belongs to a purity-passing SuSiE credible set OR qualifies for Borzoi rescue. Borzoi rescue requires BOTH a variant-causality score ≥ 0.3 AND linkage disequilibrium with the lead variant of r² ≥ 0.2. Required cellular support The overlapping promoter has positive tCRE activity OR the distal element has a passing cell-specific ABC link to the gene, in a Specific or Relevant cell subtype (L1S) or fine-grained state (L2). BOTH genetic and cellular support are required for High or Medium priority. High priority Among records meeting both minimum requirements, High requires a genetic score ≥ 0.5 AND a Layer 1 correlation > 0.3 between tCRE activity and the trait’s cellular profile across cell subtypes. Medium priority Meets both minimum requirements but not one or both additional High thresholds. The genetic score is the higher of the SuSiE posterior inclusion probability (PIP) and the Borzoi variant-causality score. Same-record evidence and aggregation Each priority requires genetic and cellular evidence supporting the SAME variant–tCRE–gene record. Do not combine thresholds or evidence from different records to create a qualifying link. A gene receives the highest priority observed among its supporting records. A tCRE summary uses supporting records for that exact tCRE, not every trait of its linked genes. Separately displayed aggregate scores do not relax the same-record rule. Limits of interpretation A priority is candidate-association evidence, not proof of a causal variant, causal gene, causal cell type or treatment efficacy. Missing evidence is unavailable, not zero. MAGMA −log10(P), displayed credibility scores, cellular-context scores and G/C tier codes must not be substituted for these eligibility tests; use the provided records and their documented fields. Meta traits · Individual traits · Gene expression · DE genes DE log fold change is a different metric from mean expression and IC score. This is the complete available browser export, limited upstream to the top 1,000 genes per population; it is not an exhaustive genome-wide differential-expression result.
All 1,000 available exported DE genes
Browsers # Gene DE log fold change Meta traits (High Priority) Individual traits (High Priority)
1 MSGN1 12.70 0 1 2 DLL3 11.17 1 1 3 HOXB-AS3 10.00 28 68 4 CITED1 9.90 — — 5 NPHS2 9.74 0 0 6 FGF17 9.61 11 32 7 WNT8A 9.56 0 0 8 CRABP2 9.45 3 4 9 HES7 9.00 10 21 10 AKAIN1 8.89 0 0 11 MIXL1 8.70 0 0 12 VWA2 8.62 0 0 13 HOXA-AS3 8.51 12 16 14 TMSB15A 8.51 — — 15 LINC01609 8.48 0 0 16 HOXB9 8.45 0 1 17 TBX6 8.41 18 46 18 FGF8 8.35 0 0 19 HOXB1 8.12 0 0 20 STRA6 8.09 26 61 21 MDK 8.07 57 347 22 MEST 7.95 3 5 23 GPC3 7.91 — — 24 PDYN 7.89 4 7 25 PRL 7.89 0 0 26 HOXC5 7.81 5 3 27 AIPL1 7.77 0 0 28 LIN28A 7.72 3 4 29 WNT3A 7.71 0 0 30 RAB3B 7.68 0 0 31 LINC01674 7.66 0 0 32 OR5V1 7.62 — — 33 GAD1 7.55 1 1 34 DKK1 7.51 0 0 35 UBE2C 7.41 9 25 36 COL2A1 7.39 7 25 37 IGF2BP1 7.38 6 13 38 TUBB2B 7.37 4 92 39 CDX2 7.32 13 21 40 FOXB1 7.30 0 0 41 FGF3 7.30 0 0 42 RBP1 7.14 1 0 43 APLNR 7.13 12 28 44 HOXB8 7.12 3 17 45 SKA1 7.12 0 0 46 URAD 7.11 10 18 47 CPXM1 7.08 3 19 48 HMGA2 7.08 13 47 49 C1QTNF4 7.05 — — 50 FOXH1 7.02 1 0 51 TAGLN3 6.98 0 0 52 EVX1 6.98 8 14 53 SP5 6.97 10 21 54 EPX 6.96 1 1 55 SPAG11A 6.95 — — 56 NTS 6.93 0 0 57 IL11 6.92 3 10 58 FZD2 6.86 5 9 59 SYT6 6.80 0 0 60 CA14 6.74 2 3 61 CCDC33 6.69 28 62 62 LAPTM4B 6.69 2 2 63 FGF19 6.69 24 52 64 FOXC1 6.68 0 0 65 CDC20 6.67 4 7 66 BIRC5 6.65 15 62 67 L1TD1 6.65 2 2 68 CLDN6 6.64 1 1 69 HOXB3 6.61 34 99 70 RIPPLY3 6.60 0 0 71 PTH 6.55 — — 72 SEZ6L 6.55 — — 73 AURKB 6.55 0 0 74 SLC7A3 6.54 — — 75 KRT19 6.54 1 1 76 LCE1D 6.53 — — 77 MLLT11 6.51 11 42 78 BAALC 6.51 1 3 79 HOXA1 6.50 8 13 80 HOXD3 6.49 21 95 81 CCNB2 6.48 15 22 82 FABP5 6.48 2 0 83 IL17B 6.47 0 0 84 TMEM190 6.45 0 0 85 TOP2A 6.45 20 58 86 GREB1 6.45 0 0 87 LIN28B 6.42 21 43 88 TCF15 6.42 1 0 89 IGDCC3 6.41 1 1 90 PRTG 6.35 0 0 91 CER1 6.33 0 0 92 CDX1 6.32 11 25 93 HOXA-AS2 6.31 8 11 94 SALL4 6.30 3 5 95 MFAP2 6.29 25 65 96 FBLN1 6.26 4 8 97 HOTAIRM1 6.26 10 13 98 HHIPL2 6.26 0 0 99 GPC2 6.25 1 0 100 TYMS 6.24 5 5 101 NES 6.23 3 22 102 MDFI 6.22 13 54 103 SELENOV 6.22 0 0 104 TEX11 6.18 — — 105 RAC3 6.16 6 21 106 DPPA4 6.15 0 0 107 KCNH5 6.13 0 0 108 SLIT1 6.12 2 3 109 IGF2BP3 6.11 1 1 110 DLGAP5 6.11 4 27 111 IGFBP2 6.11 8 12 112 CD24 6.07 0 0 113 CTXN1 6.04 3 3 114 C3orf52 6.03 2 2 115 FGFBP3 6.03 4 8 116 OLFML3 6.02 72 147 117 OTOP1 6.02 0 0 118 PCLAF 6.02 2 3 119 TMEM92 6.01 2 5 120 TUBB3 5.99 13 31 121 APOE 5.96 351 1,543 122 PIMREG 5.94 0 0 123 GBX2 5.92 0 0 124 HOXA3 5.92 20 38 125 MND1 5.92 1 3 126 ART5 5.91 1 4 127 SYT1 5.91 2 2 128 WNT5B 5.87 4 17 129 GDF15 5.87 43 83 130 KRT8 5.86 36 65 131 NPW 5.86 9 33 132 HAPLN1 5.85 6 44 133 CSRP2 5.84 0 0 134 TPX2 5.82 — — 135 PBK 5.82 10 14 136 CDT1 5.82 4 11 137 PPP1R14C 5.82 4 7 138 HJURP 5.81 29 41 139 WFDC2 5.81 36 102 140 TROAP 5.80 0 1 141 CTHRC1 5.78 0 0 142 BCAT1 5.78 3 3 143 LINC02381 5.76 10 19 144 FKBP10 5.76 15 19 145 FGF9 5.76 0 0 146 MME 5.76 2 2 147 CCNA2 5.75 0 0 148 LINC00850 5.75 — — 149 ETV4 5.75 41 202 150 UCHL1 5.74 0 0 151 RIPPLY1 5.74 — — 152 MACC1-AS1 5.73 0 0 153 COL1A2 5.72 19 39 154 CDK1 5.71 11 11 155 CTCFL 5.69 10 67 156 HOXB7 5.65 1 2 157 SSX2B 5.65 — — 158 TMEFF1 5.65 0 0 159 PDGFRA 5.64 9 40 160 COL25A1 5.63 0 0 161 REM2 5.62 2 3 162 BGN 5.59 — — 163 IGFBP4 5.59 28 80 164 COL1A1 5.58 9 15 165 NMU 5.57 0 0 166 XKR5 5.57 2 4 167 MELK 5.54 0 0 168 CDC25C 5.54 0 0 169 IL17RD 5.54 12 16 170 CST2 5.52 — — 171 FSCN1 5.52 0 0 172 LEF1 5.51 7 10 173 SPC24 5.49 93 836 174 ZNF695 5.48 2 4 175 CRABP1 5.46 0 0 176 LINC00698 5.46 0 0 177 THY1 5.45 8 20 178 ADRA2C 5.43 1 1 179 RRM2 5.42 6 6 180 TTYH1 5.42 21 24 181 TSGA13 5.41 — — 182 SP8 5.41 3 4 183 PTK7 5.40 11 45 184 MSX1 5.39 0 0 185 RND2 5.39 13 39 186 GUCA1A 5.39 21 99 187 COL11A1 5.39 2 1 188 ADAMTS20 5.38 0 0 189 FOXM1 5.38 1 2 190 PTTG1 5.37 0 0 191 PLPPR3 5.37 27 69 192 CDC25A 5.37 5 8 193 FBN2 5.34 9 19 194 PRPH 5.34 1 1 195 ZIC2 5.34 0 0 196 HOXD4 5.34 20 84 197 DSG2 5.33 4 5 198 LINC00434 5.32 0 0 199 NOTUM 5.32 12 26 200 KIF2C 5.32 0 0 201 SCD 5.30 10 44 202 TNNT1 5.30 0 1 203 FAM171A2 5.30 4 3 204 HMGB3 5.30 — — 205 DTL 5.29 13 43 206 ACTN3 5.28 3 4 207 KRT18 5.28 23 46 208 SERPINH1 5.27 22 57 209 CNTFR 5.27 0 0 210 S1PR3 5.27 3 7 211 MAD2L1 5.27 2 2 212 ASPM 5.26 23 49 213 PLAC1 5.25 — — 214 FZD9 5.25 11 42 215 HES4 5.25 7 10 216 HMGA1 5.24 15 37 217 RCOR2 5.24 0 0 218 PYCR1 5.24 2 1 219 PTH2 5.23 0 0 220 FOXC2 5.22 5 13 221 BLACAT1 5.22 2 2 222 TCEAL5 5.22 — — 223 CDH2 5.22 0 0 224 SSC4D 5.21 1 0 225 NT5DC2 5.21 72 152 226 WNT5A-AS1 5.21 6 15 227 CDH24 5.20 1 2 228 CRMP1 5.20 1 0 229 CDCA5 5.20 3 4 230 SOX11 5.20 4 9 231 CDKN1C 5.20 12 23 232 UHRF1 5.20 12 30 233 COL5A2 5.19 17 35 234 HOXB5 5.19 3 10 235 SALL1 5.18 20 39 236 NUDT11 5.17 — — 237 FABP7 5.17 1 1 238 DLL1 5.17 0 0 239 GREB1L 5.17 — — 240 GPR50 5.17 — — 241 TPM2 5.15 29 79 242 PHGDH 5.15 0 0 243 KIF20A 5.15 0 0 244 PTCH1 5.13 35 88 245 GOLGA6L2 5.13 — — 246 ROR2 5.13 2 2 247 LINC01356 5.13 0 0 248 LINC01201 5.13 — — 249 CDCA3 5.12 12 24 250 UBE2T 5.12 0 0 251 COL26A1 5.12 5 9 252 DEPDC1 5.11 0 0 253 LINC02525 5.10 1 8 254 GJC1 5.10 3 25 255 ACTC1 5.10 0 0 256 HOXD1 5.10 15 65 257 MSI1 5.09 0 0 258 ZNF90 5.08 0 0 259 GTSE1 5.07 0 2 260 CDC42EP5 5.06 1 1 261 VCX3A 5.06 — — 262 RSPO3 5.06 29 81 263 KCP 5.05 17 44 264 CENPW 5.05 17 39 265 MCM10 5.05 0 0 266 CAMKV 5.05 9 20 267 ZNF730 5.05 0 0 268 DIAPH3 5.05 1 1 269 KIF4A 5.05 — — 270 HOXC4 5.04 5 3 271 HOXC8 5.04 5 6 272 WNT5A 5.04 11 25 273 SALL3 5.04 0 0 274 PHLDA2 5.02 6 9 275 GOLGA8F 5.02 0 0 276 ECEL1 5.01 1 1 277 NNAT 5.01 0 0 278 CNN1 5.01 4 4 279 SEMA3F 5.00 29 88 280 PTCHD4 5.00 0 0 281 LAMA1 5.00 0 0 282 LINC01224 4.99 — — 283 STC2 4.99 3 13 284 EXOC3L2 4.98 19 73 285 COL4A6 4.97 — — 286 LINC02117 4.97 — — 287 C1QL4 4.96 0 0 288 C1orf232 4.96 2 14 289 LINC01980 4.96 2 3 290 SPRY4 4.95 15 57 291 BEX1 4.95 — — 292 DEPDC1B 4.95 0 0 293 NKX1-2 4.93 0 0 294 NEK2 4.93 9 21 295 CCND1 4.92 44 94 296 CIB2 4.92 10 27 297 PSAT1 4.91 0 0 298 MATN3 4.91 17 44 299 PRDM12 4.90 0 0 300 LEMD1 4.90 2 2 301 CHEK1 4.89 1 1 302 FGF10 4.88 — — 303 PEG10 4.88 1 1 304 LRP8 4.88 1 3 305 EDAR 4.88 0 0 306 TMEM97 4.87 — — 307 MYCN 4.87 1 1 308 FBN3 4.86 0 2 309 E2F7 4.86 0 0 310 PFN2 4.86 0 0 311 FLNC 4.85 15 37 312 ORC6 4.84 0 0 313 FZD7 4.84 0 0 314 NCAPG 4.84 1 1 315 BUB1 4.84 4 9 316 CDCA8 4.83 1 5 317 GGH 4.83 8 10 318 SKA3 4.83 0 0 319 CBX2 4.81 2 2 320 BMP7 4.81 7 60 321 LINGO1 4.81 1 1 322 CCDC169 4.80 0 0 323 CCDC169-SOHLH2 4.80 0 0 324 KCNQ2 4.80 11 17 325 ZSCAN10 4.80 0 0 326 PLP1 4.80 — — 327 KIFC1 4.79 1 1 328 NEIL3 4.79 0 0 329 MEX3A 4.79 10 18 330 EGFLAM-AS1 4.78 0 0 331 DACT1 4.78 0 6 332 USH1G 4.77 3 13 333 TSPAN6 4.76 — — 334 MMP2 4.75 4 6 335 ECM1 4.75 60 158 336 CKS1B 4.74 5 10 337 RDM1 4.74 7 8 338 PLK1 4.74 0 0 339 CKAP2L 4.73 6 23 340 GJA1 4.73 3 10 341 MAGED4 4.72 — — 342 TICRR 4.71 1 1 343 AUNIP 4.71 2 2 344 CEP55 4.71 0 0 345 TRIM6-TRIM34 4.71 3 2 346 TRIM6 4.69 3 2 347 HS6ST2 4.69 — — 348 SACS-AS1 4.69 0 0 349 CENPV 4.69 5 8 350 FAM163A 4.67 0 0 351 BEX3 4.67 — — 352 ATP1B2 4.66 25 53 353 NETO1 4.66 0 0 354 NREP 4.66 1 2 355 FSTL1 4.66 1 1 356 GPR3 4.66 11 26 357 DSP 4.65 9 96 358 RAD51AP1 4.64 2 2 359 CERS1 4.64 2 2 360 ST6GAL2 4.64 0 0 361 MFAP4 4.64 1 6 362 CLPSL2 4.63 17 57 363 SLIT2 4.63 0 0 364 CST1 4.63 — — 365 CDC45 4.62 1 1 366 PIF1 4.62 109 146 367 FN1 4.61 29 100 368 NAT14 4.61 9 25 369 LINC01180 4.60 — — 370 PGF 4.60 2 2 371 PTN 4.60 0 0 372 TTK 4.59 0 0 373 ANKRD18B 4.59 0 0 374 DSC3 4.59 5 6 375 DRAXIN 4.58 2 1 376 CLSPN 4.58 1 2 377 WFDC10A 4.57 0 0 378 TET1 4.57 1 1 379 PCSK9 4.56 76 701 380 LINC01152 4.56 1 0 381 GRIN3B 4.56 20 104 382 TMEM158 4.56 4 4 383 MORN4 4.56 2 2 384 ERCC6L 4.56 — — 385 GINS2 4.56 1 5 386 TMEM98 4.56 2 2 387 RTN4R 4.56 3 3 388 CYP27C1 4.55 8 12 389 BUB1B 4.55 5 15 390 MYH10 4.54 1 1 391 NKAIN1 4.54 8 16 392 ARHGAP11A 4.54 0 0 393 SLC1A6 4.53 0 0 394 KAZN 4.53 2 10 395 LINC00491 4.52 0 0 396 SPC25 4.52 13 44 397 NUSAP1 4.52 1 3 398 SPARC 4.51 1 2 399 ALX3 4.51 2 5 400 TCEAL7 4.51 — — 401 MFGE8 4.50 17 46 402 APOC1 4.49 301 1,434 403 IQGAP3 4.49 34 104 404 KHDRBS3 4.48 1 1 405 VRTN 4.48 2 7 406 MYBL2 4.48 10 32 407 ADAMTS15 4.48 10 17 408 LINC02143 4.47 — — 409 NUDT10 4.47 — — 410 CDCA2 4.47 8 16 411 KIF15 4.47 0 0 412 ARID3A 4.47 21 94 413 STMN1 4.47 0 0 414 MEIS3 4.47 11 22 415 KCNG1 4.47 0 0 416 CYYR1 4.45 1 1 417 TAC1 4.45 0 0 418 PLA2G3 4.44 7 34 419 MSX2 4.44 0 0 420 MAFA-AS1 4.44 9 6 421 FGF2 4.43 2 2 422 NCAPH 4.43 — — 423 KIF18B 4.43 0 0 424 SIX4 4.43 0 0 425 LINC01571 4.42 2 2 426 MAFA 4.42 8 5 427 ZNF385C 4.42 2 18 428 SRSF12 4.42 0 0 429 CCNB1 4.41 4 3 430 IGF2BP2 4.41 6 11 431 PTPRZ1 4.41 1 1 432 CNMD 4.40 1 1 433 FKBP1B 4.40 6 35 434 ERICH2 4.40 0 0 435 ALX1 4.40 0 0 436 ST6GALNAC5 4.40 0 0 437 APLP1 4.39 0 0 438 NALT1 4.39 49 205 439 REEP2 4.39 1 1 440 TRH 4.39 1 2 441 PYY 4.39 10 14 442 MSMO1 4.39 1 1 443 SNAI1 4.38 4 13 444 NXPH4 4.38 33 191 445 COL4A2 4.38 31 70 446 CBS 4.38 0 0 447 LINC02428 4.37 4 7 448 EXO1 4.37 0 0 449 TENM4 4.36 1 1 450 HES6 4.36 8 20 451 NEFL 4.36 0 0 452 TRIM71 4.36 3 10 453 CECR2 4.36 7 7 454 MGST1 4.36 2 1 455 MKI67 4.35 0 0 456 SALL2 4.35 0 0 457 SP6 4.35 5 17 458 LINC01456 4.35 — — 459 FOXC2-AS1 4.35 3 13 460 PLEKHG4B 4.35 2 6 461 KC6 4.34 0 0 462 TEAD2 4.34 1 2 463 RAD54L 4.34 6 12 464 DNMT3B 4.34 1 2 465 OCM2 4.34 0 0 466 ENPP2 4.33 8 14 467 RASL10A 4.33 0 0 468 HOXA7 4.32 11 15 469 NRP2 4.32 6 5 470 CNIH2 4.32 0 0 471 CASC9 4.32 0 0 472 TENM1 4.31 — — 473 SGO1 4.31 0 0 474 KIF26B 4.31 0 0 475 ZWINT 4.31 0 0 476 APELA 4.30 0 0 477 ACSS3 4.29 1 2 478 EGFLAM 4.29 0 0 479 VPS37D 4.29 214 1,102 480 VCAN 4.28 11 255 481 CRISPLD1 4.28 0 0 482 NUF2 4.28 0 0 483 DUSP15 4.28 3 8 484 L1CAM 4.28 — — 485 HMX1 4.28 0 0 486 LINC01124 4.27 4 3 487 OTOG 4.27 0 0 488 EFNB3 4.26 23 51 489 CDKN3 4.26 0 0 490 E2F8 4.26 0 0 491 FIBCD1 4.26 0 0 492 ICAM5 4.26 6 12 493 ANLN 4.25 1 3 494 GAL 4.25 6 12 495 TNFRSF10C 4.25 20 51 496 HMMR 4.24 0 0 497 MYL6B 4.23 0 0 498 ST8SIA2 4.23 3 14 499 VWCE 4.23 1 7 500 EVA1B 4.23 16 55 501 NPM3 4.23 0 0 502 LINC01054 4.22 2 2 503 TMEM132A 4.22 18 66 504 TMEM108 4.21 0 1 505 FAM72C 4.21 — — 506 HEPH 4.21 — — 507 CCNB1IP1 4.21 0 0 508 CDCA7 4.20 1 3 509 CKS2 4.20 0 0 510 ANOS1 4.20 — — 511 ADGRV1 4.19 0 0 512 HAS2 4.19 5 13 513 ADAMTS12 4.18 1 1 514 ORC1 4.18 0 0 515 ZNF732 4.18 1 1 516 RBPMS2 4.18 96 135 517 LINC01918 4.18 0 0 518 GAREM2 4.18 4 8 519 DNA2 4.17 1 3 520 PHF21B 4.16 3 4 521 NME1 4.16 0 0 522 TNFRSF11A 4.16 2 4 523 NME1-NME2 4.16 0 0 524 LOXL2 4.16 13 42 525 GPX8 4.16 8 21 526 KHDC3L 4.16 0 0 527 KCNT2 4.16 57 89 528 PAICS 4.15 0 0 529 MLLT3 4.15 2 1 530 LIPG 4.15 52 274 531 DUSP6 4.14 29 40 532 RASL10B 4.14 3 4 533 KIF14 4.14 0 1 534 INHBE 4.13 40 200 535 CENPF 4.12 0 1 536 PRKG1-AS1 4.12 0 0 537 LRRC10B 4.11 0 1 538 CPA1 4.11 9 10 539 CTAG2 4.11 — — 540 MPL 4.10 10 28 541 STC1 4.10 6 19 542 TULP1 4.10 26 75 543 ATRNL1 4.10 0 0 544 TRIM36 4.09 0 0 545 POLQ 4.09 20 48 546 MAP1B 4.09 0 0 547 AFAP1L2 4.08 1 2 548 CPA6 4.08 1 1 549 C18orf54 4.08 3 0 550 CENPH 4.08 4 3 551 FZD10 4.07 — — 552 PCDH19 4.07 — — 553 GPM6B 4.07 — — 554 KIF5C 4.07 0 0 555 ASGR1 4.06 184 416 556 PRR35 4.06 7 20 557 BUB1B-PAK6 4.05 — — 558 LRRN1 4.05 0 0 559 LINC00960 4.05 1 1 560 GABRA3 4.05 — — 561 MAPK15 4.04 4 4 562 RIMS4 4.04 8 11 563 GPR20 4.04 29 51 564 FAM72D 4.04 — — 565 GPC4 4.04 — — 566 PARD6G 4.03 2 6 567 MMP14 4.03 28 53 568 NEFM 4.03 0 0 569 PDLIM4 4.02 171 263 570 DES 4.02 9 123 571 TEX101 4.02 — — 572 NCS1 4.02 0 0 573 NDC80 4.01 0 0 574 SNCG 4.01 0 0 575 ENAH 4.01 4 4 576 ELOVL6 4.01 7 11 577 MYCNOS 4.01 1 1 578 PLTP 4.01 18 36 579 AKAP12 4.01 4 13 580 GOLGA8H 4.01 4 8 581 EPHB3 4.01 0 0 582 HOXC6 4.00 9 9 583 SCG5 4.00 1 1 584 GINS1 3.99 0 0 585 SFRP2 3.98 1 4 586 HAS2-AS1 3.97 5 13 587 TUBB 3.97 165 310 588 WFIKKN1 3.97 5 13 589 ATP1A2 3.97 1 4 590 TUSC3 3.97 10 10 591 CSPG4 3.97 2 10 592 CLDN11 3.96 0 0 593 GDNF 3.96 6 20 594 IGSF1 3.96 — — 595 KIF23 3.96 0 0 596 ULBP3 3.94 5 7 597 PRSS56 3.94 1 1 598 CNTNAP2 3.93 0 0 599 ODF2-AS1 3.93 — — 600 NKD1 3.92 5 10 601 LINC01209 3.92 — — 602 ATP6V1G2-DDX39B 3.92 69 185 603 DKKL1 3.92 1 2 604 TMSB15B 3.91 — — 605 SDC2 3.91 1 3 606 FADS2 3.90 64 209 607 COL5A1 3.90 4 10 608 WWC2 3.89 1 2 609 LINC02127 3.89 — — 610 LINC02249 3.89 0 0 611 PDLIM1 3.89 19 37 612 SNCB 3.88 1 1 613 LINC01248 3.88 4 9 614 RASL11B 3.88 0 0 615 TCEAL2 3.88 — — 616 PLK4 3.88 0 0 617 FGF18 3.88 4 6 618 B4GALT2 3.87 3 5 619 HMGCS1 3.87 — — 620 PAWR 3.87 4 4 621 DPF1 3.87 5 13 622 FADS1 3.87 63 361 623 PNMA8A 3.87 19 52 624 PROCR 3.87 39 86 625 PMEL 3.87 1 0 626 DSG2-AS1 3.86 2 2 627 VGF 3.86 21 34 628 ELFN1 3.86 5 8 629 VASH2 3.85 0 0 630 ITGA2B 3.85 4 3 631 AIF1 3.85 433 801 632 TRIP13 3.85 1 1 633 CCDC63 3.85 4 5 634 FAM216A 3.85 1 4 635 PRSS8 3.85 14 14 636 CPA2 3.84 0 0 637 CD276 3.84 13 27 638 ATP6V1G2 3.84 73 194 639 MMP16 3.83 0 0 640 DPPA2 3.83 0 0 641 KNL1 3.83 7 7 642 SLC8A3 3.82 2 2 643 LINC02238 3.82 0 0 644 LINC00540 3.82 0 0 645 CLIC1 3.81 159 256 646 HS3ST3A1 3.81 2 10 647 TTLL8 3.81 2 4 648 MCM2 3.81 8 10 649 OIP5 3.81 0 0 650 NR2F6 3.81 14 44 651 LINC01162 3.81 0 0 652 EFNA3 3.80 45 80 653 SHCBP1 3.80 0 0 654 CDH11 3.80 1 5 655 ITM2C 3.80 0 0 656 IGFBPL1 3.80 1 1 657 GPHA2 3.80 0 0 658 PXDN 3.79 5 25 659 NRTN 3.79 23 26 660 DBN1 3.79 18 31 661 AK4 3.79 3 3 662 ARHGEF39 3.79 17 49 663 DNAH3 3.78 3 4 664 HACD1 3.77 2 2 665 RAB13 3.77 8 20 666 PCDH18 3.76 0 5 667 C1orf54 3.76 7 10 668 MYO3A 3.76 0 0 669 RPL39L 3.76 2 2 670 SOX2 3.75 0 0 671 TENM3 3.75 0 0 672 ARSI 3.75 9 21 673 EFNA2 3.75 1 1 674 EPHA2 3.75 46 72 675 LINC01905 3.74 0 0 676 ISLR2 3.74 30 68 677 ID3 3.74 4 9 678 CTNNA2 3.74 0 0 679 PPAT 3.73 0 0 680 TEX19 3.73 7 23 681 SLC17A7 3.73 10 24 682 PERP 3.73 16 32 683 VPS9D1-AS1 3.73 27 43 684 VSTM2L 3.73 2 4 685 SQLE 3.72 58 343 686 SYNPR-AS1 3.72 0 0 687 WNK3 3.72 — — 688 LOXL1 3.72 52 110 689 RTKN2 3.71 21 42 690 CD200R1L 3.71 3 3 691 ZIC3 3.71 — — 692 SLC16A9 3.71 2 1 693 CDC6 3.71 12 41 694 ZNF883 3.70 0 0 695 BMP3 3.70 1 4 696 EFNB1 3.70 — — 697 HIF3A 3.70 12 50 698 HOXB-AS4 3.70 0 0 699 NR6A1 3.69 5 7 700 G6PC3 3.69 0 0 701 LINC00605 3.69 8 14 702 WLS 3.69 0 4 703 COL13A1 3.69 2 4 704 CENPE 3.69 2 1 705 WDR86 3.69 4 7 706 CACNG7 3.68 6 7 707 BASP1 3.68 0 0 708 CCDC34 3.68 0 0 709 THBS4 3.67 5 20 710 GPR161 3.67 2 3 711 SPEG 3.67 11 134 712 SPAG5 3.67 — — 713 HSD17B14 3.67 16 18 714 WWC2-AS1 3.67 1 1 715 CYB5R2 3.66 0 0 716 NID2 3.66 7 17 717 CMBL 3.66 0 0 718 HMGCR 3.66 35 69 719 LMNB1 3.66 2 5 720 VASN 3.66 28 75 721 PAX2 3.65 3 3 722 LAMB1 3.65 9 16 723 NXN 3.65 1 1 724 MIR4713HG 3.65 0 0 725 GPRASP2 3.64 — — 726 YAP1 3.64 2 2 727 TMEM59L 3.64 16 25 728 ISYNA1 3.64 57 136 729 FBXO17 3.64 11 19 730 CKB 3.63 18 40 731 MARCKS 3.63 1 2 732 UNC5C 3.63 4 7 733 LINC01682 3.63 1 1 734 AMELY 3.63 — — 735 NKAIN4 3.63 7 7 736 DEPDC1-AS1 3.63 0 0 737 COL18A1 3.63 51 139 738 NYAP1 3.62 16 45 739 LINC01500 3.62 1 39 740 PPP1R14A 3.61 9 20 741 LDHB 3.61 18 32 742 DPCD 3.61 0 0 743 NECTIN2 3.61 217 1,214 744 EDIL3 3.61 2 2 745 TBL1Y 3.61 — — 746 CDH4 3.61 2 2 747 BCAM 3.61 119 896 748 ZFP42 3.60 — — 749 FXYD6-FXYD2 3.60 8 8 750 CACNG4 3.60 0 0 751 GAL3ST3 3.60 0 0 752 MXRA8 3.59 7 40 753 AHCY 3.59 2 2 754 POC1A 3.59 72 153 755 QPRT 3.59 5 18 756 ASNS 3.59 22 68 757 NGFR 3.59 4 11 758 TUBA1B 3.59 0 0 759 VANGL2 3.58 2 3 760 PDXP 3.58 15 36 761 ISLR 3.58 28 62 762 NQO1 3.58 2 4 763 NALCN-AS1 3.58 0 0 764 PSMB5 3.57 0 0 765 PCOLCE2 3.57 7 20 766 LAMC1 3.57 60 136 767 KIRREL2 3.57 1 1 768 ARG2 3.56 0 0 769 CNN3 3.56 2 3 770 FANCI 3.56 10 26 771 FOXD1-AS1 3.56 — — 772 GNGT1 3.56 0 1 773 PKMYT1 3.55 0 1 774 RIMS2 3.55 0 1 775 SOX14 3.55 0 0 776 TSGA10IP 3.55 9 18 777 UBE2S 3.55 1 1 778 C19orf84 3.54 2 6 779 SOX7 3.54 86 466 780 NIPSNAP1 3.54 0 1 781 ZNF436-AS1 3.54 17 84 782 ZNF358 3.54 0 0 783 PTGR1 3.54 5 8 784 GPC6-AS1 3.54 — — 785 CPA5 3.54 1 2 786 SEMA6A 3.53 1 2 787 NME4 3.53 25 44 788 KREMEN2 3.53 0 0 789 RCN1 3.53 5 11 790 ZNF93 3.53 1 2 791 HTR7 3.53 0 3 792 GPR143 3.52 — — 793 TMEM35A 3.52 — — 794 LIN7A 3.52 1 2 795 SSTR2 3.52 1 2 796 TRPV4 3.52 7 21 797 PARPBP 3.51 0 0 798 CLIP3 3.51 1 1 799 ADAMTS6 3.51 1 1 800 LINC01901 3.51 0 0 801 COL4A1 3.51 38 107 802 PCDHB2 3.51 0 0 803 NID1 3.50 6 7 804 EBLN1 3.50 — — 805 VENTX 3.50 3 4 806 GNAS-AS1 3.50 9 56 807 COL4A2-AS1 3.50 — — 808 SULT4A1 3.50 249 495 809 DMRT2 3.49 6 11 810 FST 3.49 15 35 811 KIF18A 3.49 0 0 812 ACTA2 3.49 5 5 813 DPYSL3 3.49 1 1 814 EME1 3.48 2 2 815 SMO 3.48 3 10 816 OR1L6 3.48 — — 817 LINC02253 3.48 0 0 818 IQCF1 3.48 — — 819 SCML2 3.47 — — 820 C14orf39 3.47 1 1 821 GCSH 3.46 1 4 822 CADM1 3.46 5 9 823 KCNN1 3.46 10 42 824 FBLIM1 3.46 12 35 825 LINC00868 3.46 — — 826 ALDH7A1 3.46 0 3 827 PCSK5 3.45 1 5 828 TEAD4 3.45 1 2 829 MMP23B 3.45 2 14 830 CACHD1 3.45 0 0 831 NTN1 3.45 4 17 832 GYG2 3.45 — — 833 E2F5 3.44 1 1 834 MESP2 3.44 9 20 835 MTHFD2 3.44 2 1 836 PDGFRB 3.44 11 25 837 LINC01766 3.43 0 0 838 MTHFD1L 3.43 0 1 839 SMIM24 3.43 14 27 840 NDN 3.43 — — 841 GNAL 3.43 2 3 842 MRPL23-AS1 3.43 11 34 843 HES5 3.43 2 7 844 CCDC160 3.43 — — 845 SLC29A4 3.42 1 2 846 ST8SIA6 3.42 4 27 847 ANTXR1 3.42 1 3 848 CHRNA9 3.42 1 1 849 SLC7A11 3.42 0 0 850 RGS20 3.42 — — 851 SLC35G6 3.41 12 22 852 TRAF4 3.41 — — 853 GRM7-AS3 3.40 0 0 854 ACAT2 3.40 22 41 855 KCNH2 3.40 28 62 856 PCAT6 3.40 0 0 857 SV2A 3.40 14 36 858 C19orf81 3.40 0 0 859 SMC6 3.40 1 2 860 ARHGEF25 3.40 15 52 861 MRC2 3.39 14 64 862 TMEM215 3.39 3 7 863 STON1 3.38 5 10 864 IGDCC4 3.38 1 1 865 LYPD6 3.38 — — 866 MAST1 3.38 1 1 867 KPNA2 3.37 2 4 868 EDA2R 3.37 — — 869 TAC3 3.37 14 43 870 PLCH1 3.36 1 2 871 BRIP1 3.36 0 0 872 CLDN19 3.36 0 0 873 CRYGD 3.36 0 0 874 SPRY2 3.36 1 1 875 SMOC1 3.36 7 7 876 LINC02255 3.36 1 1 877 BIRC6-AS1 3.35 — — 878 CBARP 3.35 8 15 879 C5orf34 3.35 1 3 880 DNM1P35 3.35 4 14 881 HOXB6 3.35 12 59 882 FGFR4 3.35 18 59 883 FKBP7 3.34 0 0 884 SLC16A1 3.34 2 2 885 PTMS 3.34 15 37 886 VWA5B1 3.34 0 0 887 PRC1 3.34 1 2 888 GFRA2 3.34 11 37 889 LOXL1-AS1 3.34 44 98 890 RCN2 3.34 0 0 891 SNAP25 3.34 2 2 892 GPR63 3.34 5 43 893 ITGB5 3.34 28 43 894 LCMT1-AS2 3.34 0 0 895 SFN 3.33 5 1 896 STON1-GTF2A1L 3.33 2 5 897 DZIP1 3.33 10 26 898 CENPM 3.33 29 65 899 S100A13 3.33 8 14 900 LINC01234 3.33 0 0 901 HELLS 3.33 4 6 902 LINC02211 3.32 0 0 903 MEGF11 3.32 0 0 904 DNAH14 3.32 0 0 905 CHRND 3.32 1 3 906 BIN1 3.32 9 15 907 GRID2IP 3.32 15 17 908 E2F1 3.32 5 7 909 FIRRE 3.32 — — 910 RGMA 3.32 3 4 911 STARD4-AS1 3.31 1 2 912 ATP2A1-AS1 3.31 0 24 913 KANK4 3.31 2 2 914 TXNDC5 3.31 9 16 915 CENPN 3.31 0 0 916 BARX1 3.31 2 5 917 SERPINE2 3.30 6 14 918 PLXNA2 3.30 20 94 919 CASC15 3.30 4 5 920 DNM1 3.30 2 3 921 RSPO4 3.30 0 0 922 FOXS1 3.30 3 8 923 NRARP 3.30 2 3 924 RRAS 3.30 13 45 925 DIAPH3-AS2 3.29 — — 926 KRT72 3.29 19 28 927 GPRC5C 3.29 22 50 928 SFRP1 3.29 2 12 929 ZNF385A 3.28 94 96 930 LINC01967 3.28 2 3 931 DACT3 3.28 14 22 932 GJB7 3.28 0 0 933 FASN 3.28 23 38 934 ACOT7 3.28 7 165 935 ASS1 3.28 1 2 936 GPC6 3.28 1 2 937 DMKN 3.28 67 112 938 ETV1 3.28 0 0 939 TIMELESS 3.28 1 4 940 TP53I11 3.27 3 6 941 RNASE1 3.27 4 4 942 ZFR2 3.27 0 0 943 LINC01971 3.27 11 15 944 CLEC11A 3.27 0 0 945 GCAT 3.27 30 82 946 ARHGAP36 3.26 — — 947 AGBL5-AS1 3.26 6 10 948 TIE1 3.26 18 87 949 LIN28B-AS1 3.26 23 58 950 CCNG1 3.26 0 0 951 PDZRN3 3.26 6 5 952 KNSTRN 3.26 4 14 953 GALNT8 3.26 0 1 954 TK1 3.26 15 62 955 ZNF114 3.26 1 1 956 DLGAP1 3.25 0 0 957 FBXO5 3.25 0 1 958 LINC02562 3.25 0 0 959 CPT1C 3.25 1 1 960 RAD54B 3.25 3 3 961 CCDC150 3.25 3 32 962 STIL 3.25 10 12 963 CNTNAP1 3.25 8 21 964 PHYHIP 3.24 14 32 965 CCND2 3.24 11 45 966 F2RL1 3.24 13 56 967 TRO 3.24 — — 968 LINC02078 3.24 0 0 969 RNASEH2A 3.24 0 0 970 PNPLA3 3.24 251 496 971 CDC7 3.23 7 17 972 RGPD4-AS1 3.23 — — 973 GPR27 3.23 2 2 974 CXADR 3.23 0 0 975 HOXC9 3.23 6 8 976 NTPCR 3.22 2 5 977 EFHD1 3.22 2 7 978 COL4A5 3.22 — — 979 ADGRL3 3.22 0 0 980 BTBD17 3.22 8 16 981 PTPN13 3.22 11 125 982 NPM1 3.22 3 5 983 PRR11 3.22 0 0 984 CILP2 3.21 50 108 985 IGFBP5 3.21 6 11 986 TCF7L1 3.21 14 23 987 KIF11 3.21 0 3 988 HOMER3 3.21 57 338 989 DHCR24 3.21 6 37 990 WDHD1 3.21 2 17 991 RAB34 3.21 — — 992 FXYD6 3.21 8 8 993 SHMT2 3.21 35 201 994 METRN 3.21 0 1 995 MTNR1A 3.20 3 12 996 INPP5J 3.20 12 40 997 SLC16A3 3.20 15 37 998 HAGLROS 3.20 22 88 999 PHOX2A 3.20 9 9 1000 LRRC4B 3.20 0 0