Association counts use unique genes with 01-High Priority evidence and unique cells in the authored Specific tier (not the IC-score significance threshold). Reverse counts list meta traits and individual traits separately; these are overlapping levels of evidence, not independent totals. Counts cover the full available catalogue, not the displayed rows or sampled UMAP. Unavailable profiles are excluded from reverse counts; a dash means unavailable or an ambiguous identity, not zero. The browser initially shows 50 rows; choose Rows to change this. Complete rows remain in the HTML, and ordinary page links expose any continuation pages for AI readers and crawlers.

HPC.MPP_activated: DE genes

How association tiers are defined — cell–trait and gene–trait

SCREATE tier definitions supplied by the atlas curator. This methods note explains the prepared classifications; it does not recompute or change any report scores or tiers.

Cell–trait tiers

Cell–trait links: Identify cell types whose regulatory activity is associated with a trait’s genetic signal.
Required for Specific or Relevant: The ICE-CREAM score derived from the mean metacell Z score must be ≥ 5.39, with BOTH nominal and adjusted ICE-CREAM P values ≤ 0.05.
Specific (Tier 1): Also meets all cell-set enrichment analysis (CSEA) criteria in at least one tested comparison: nominal P ≤ 0.05 AND adjusted P ≤ 0.05 AND normalized enrichment score (NES) ≥ 1, all in that comparison. This indicates that trait-associated activity is concentrated in this cell type relative to the tested background.
Relevant (Tier 2): Meets the ICE-CREAM requirements but not the additional CSEA criteria. The cell type may share trait-associated activity with other cell types.
Interpretation and report values: CSEA is cell-set enrichment analysis, analogous to gene-set enrichment analysis but using sets of cells along a ranked list of ICE-CREAM scores. The eligibility score derived from the mean metacell Z score is not the displayed mean IC score. Do not infer a tier from the displayed mean, its descriptive Significance column, or a single CSEA summary value. Reports preserve prepared tiers; Other means an available association outside Specific/Relevant, and unavailable is not zero or proof of biological irrelevance.
Meta traits and individual traits: Use the prepared tier for the exact meta trait or individual trait. A meta trait’s Best child CSEA FDR is the lowest available child FDR, not a combined or meta-trait significance test. Its displayed mean child NES is descriptive, not a new CSEA test. These summaries must not be used to reconstruct or override the meta-trait tier.

Gene–trait priorities (variant–tCRE–gene evidence)

Variant–tCRE–gene links: Candidate variants connect to genes through overlapping promoters or distal transcribed cis-regulatory elements (tCREs) linked to gene promoters by the Activity-by-Contact (ABC) model.
Required genetic support: The variant belongs to a purity-passing SuSiE credible set OR qualifies for Borzoi rescue. Borzoi rescue requires BOTH a variant-causality score ≥ 0.3 AND linkage disequilibrium with the lead variant of r² ≥ 0.2.
Required cellular support: The overlapping promoter has positive tCRE activity OR the distal element has a passing cell-specific ABC link to the gene, in a Specific or Relevant cell subtype (L1S) or fine-grained state (L2). BOTH genetic and cellular support are required for High or Medium priority.
High priority: Among records meeting both minimum requirements, High requires a genetic score ≥ 0.5 AND a Layer 1 correlation > 0.3 between tCRE activity and the trait’s cellular profile across cell subtypes.
Medium priority: Meets both minimum requirements but not one or both additional High thresholds. The genetic score is the higher of the SuSiE posterior inclusion probability (PIP) and the Borzoi variant-causality score.
Same-record evidence and aggregation: Each priority requires genetic and cellular evidence supporting the SAME variant–tCRE–gene record. Do not combine thresholds or evidence from different records to create a qualifying link. A gene receives the highest priority observed among its supporting records. A tCRE summary uses supporting records for that exact tCRE, not every trait of its linked genes. Separately displayed aggregate scores do not relax the same-record rule.
Limits of interpretation: A priority is candidate-association evidence, not proof of a causal variant, causal gene, causal cell type or treatment efficacy. Missing evidence is unavailable, not zero. MAGMA −log10(P), displayed credibility scores, cellular-context scores and G/C tier codes must not be substituted for these eligibility tests; use the provided records and their documented fields.

DE log fold change is a different metric from mean expression and IC score. This is the complete available browser export, limited upstream to the top 1,000 genes per population; it is not an exhaustive genome-wide differential-expression result.

All 1,000 available exported DE genes
#	Gene	DE log fold change	Meta traits (High Priority)	Individual traits (High Priority)
1	IGLL1	11.68	0	0
2	AVP	11.08	1	1
3	PRSS57	10.37	4	2
4	CPA3	10.19	11	12
5	LINC01538	9.68	3	3
6	C1QTNF4	9.04	—	—
7	CRYGD	8.98	0	0
8	SMIM24	8.66	14	27
9	SPINK2	8.60	18	43
10	HEMGN	8.15	2	3
11	CRHBP	8.10	1	11
12	FLT3	7.77	6	18
13	HTR1F	7.75	0	1
14	MYB	7.67	0	0
15	STOML3	7.37	0	0
16	CYTL1	7.16	0	1
17	TSPAN16	7.15	0	2
18	MPL	7.09	10	28
19	TRH	7.07	1	2
20	GATA1	7.01	—	—
21	NPR3	7.00	11	81
22	HPGDS	6.99	11	34
23	GATA2	6.82	25	50
24	LINC01065	6.80	0	0
25	MS4A3	6.75	33	65
26	NFE2	6.72	7	9
27	LINC01475	6.67	0	0
28	GPR21	6.66	1	1
29	SMIM28	6.58	—	—
30	LINC02160	6.57	1	2
31	EREG	6.50	12	26
32	GNA15	6.50	9	20
33	KIT	6.48	6	33
34	PROM1	6.37	2	2
35	C2orf66	6.37	0	0
36	EMID1	6.36	1	3
37	VPREB1	6.35	0	0
38	HMGA2	6.31	13	47
39	CD34	6.27	24	109
40	MZB1	6.26	1	0
41	SPNS3	6.18	1	0
42	ERG	6.15	35	80
43	LINC01819	6.13	22	49
44	CHST13	6.09	12	26
45	SVOPL	6.06	1	18
46	MPO	6.05	17	50
47	KLF1	6.04	7	35
48	BAALC	6.02	1	3
49	CPXM1	6.01	3	19
50	ST8SIA6	5.95	4	27
51	SLC22A16	5.92	0	0
52	GFI1B	5.91	2	3
53	CXCL8	5.90	2	6
54	AIF1	5.87	433	801
55	BSPRY	5.85	1	1
56	TPSD1	5.84	0	1
57	DPPA4	5.83	0	0
58	HOXA9	5.79	13	44
59	LINC00700	5.77	—	—
60	GCSAML	5.76	5	21
61	FAM124B	5.74	5	9
62	SLFN14	5.74	0	7
63	TRIM58	5.73	7	42
64	SMCR2	5.73	—	—
65	CCDC175	5.71	1	6
66	DPEP3	5.71	18	42
67	NKAIN2	5.70	0	0
68	AREG	5.69	2	6
69	HOXA3	5.68	20	38
70	BAALC-AS2	5.67	0	0
71	PRSS2	5.66	2	1
72	CLDN20	5.65	0	0
73	P2RX1	5.65	29	42
74	CSF3R	5.65	14	53
75	MMRN1	5.65	3	5
76	KCNK17	5.62	2	6
77	LMO2	5.59	2	5
78	LRRC70	5.54	0	0
79	CD69	5.40	0	0
80	BEND4	5.40	0	0
81	ATP8B4	5.38	7	22
82	MLC1	5.37	3	16
83	XXYLT1-AS2	5.35	3	4
84	KCNQ5-AS1	5.30	—	—
85	MYCT1	5.24	2	4
86	LKAAEAR1	5.23	21	61
87	LINC01231	5.22	0	0
88	LINC02500	5.22	—	—
89	CDCA7	5.21	1	3
90	HOXA10-AS	5.19	10	13
91	LYL1	5.19	18	63
92	NANOS3	5.16	8	32
93	ANGPT1	5.13	0	3
94	HDC	5.12	0	0
95	PDE6G	5.10	1	1
96	CBX2	5.09	2	2
97	TFEC	5.09	9	81
98	KCNG2	5.08	5	5
99	SCT	5.07	6	12
100	C3orf80	5.05	0	0
101	MPIG6B	5.03	1	15
102	LINC02265	5.03	9	12
103	LINC01765	5.03	0	1
104	ZNF711	5.01	—	—
105	KIAA0087	5.00	0	0
106	SLC18A2	5.00	0	0
107	LINC02232	5.00	0	0
108	IGF2BP3	4.98	1	1
109	TAL1	4.97	9	11
110	LINC00322	4.93	0	0
111	LINC00421	4.92	0	0
112	ATP2A1	4.92	3	4
113	TPSB2	4.91	0	0
114	GAPT	4.89	0	0
115	XACT	4.85	—	—
116	WDR49	4.84	0	0
117	MIXL1	4.83	0	0
118	NT5M	4.82	10	38
119	SHD	4.81	5	12
120	FAM117A	4.81	4	16
121	VWDE	4.78	0	0
122	CLEC20A	4.78	0	0
123	FOSL1	4.78	26	51
124	LINC02370	4.76	—	—
125	HLTF-AS1	4.75	1	0
126	WASIR2	4.73	3	4
127	CHRM3	4.71	0	0
128	BCL11A	4.69	5	12
129	GATA2-AS1	4.68	23	47
130	MSRB3	4.68	0	0
131	SLC8A3	4.67	2	2
132	LINC02415	4.67	0	2
133	MCTP1	4.66	1	1
134	SOX4	4.66	0	0
135	TESMIN	4.65	39	288
136	MED12L	4.64	0	0
137	PTGS2	4.64	2	4
138	LINC00051	4.62	13	22
139	HOPX	4.61	5	7
140	DACH1	4.60	0	0
141	ERVFRD-1	4.57	1	1
142	IRAK3	4.57	2	3
143	EGR4	4.54	0	0
144	IGF2BP2	4.53	6	11
145	DLGAP2	4.52	1	1
146	ITGA9	4.51	4	5
147	LINC01864	4.50	0	0
148	ZNF474	4.49	4	9
149	CALN1	4.49	0	1
150	OR5AN1	4.48	—	—
151	TEC	4.48	11	21
152	ALG1L2	4.47	0	0
153	LAT2	4.47	34	78
154	SPI1	4.45	—	—
155	RAMP1	4.45	10	21
156	GLYATL2	4.43	0	0
157	RAB37	4.43	13	58
158	HBD	4.42	1	9
159	LAPTM4B	4.42	2	2
160	NOG	4.36	0	0
161	CD109	4.36	0	0
162	SCN9A	4.36	0	0
163	LINC01257	4.35	0	2
164	NRIP1	4.34	13	24
165	MDK	4.32	57	347
166	HLA-DRA	4.32	693	1,237
167	CLEC11A	4.30	0	0
168	DTL	4.30	13	43
169	LINC02014	4.30	0	0
170	CALCRL	4.30	53	105
171	TEKT1	4.30	14	42
172	CLDN10	4.29	1	3
173	TMIGD2	4.29	7	17
174	AQP10	4.28	1	1
175	CYYR1	4.27	1	1
176	IL18	4.26	4	3
177	SELL	4.25	26	113
178	PTPRCAP	4.25	7	39
179	CDH9	4.25	0	0
180	PMAIP1	4.24	2	4
181	EGR1	4.23	1	1
182	SPOCK3	4.22	0	0
183	ZNF804A	4.22	0	0
184	CCDC63	4.21	4	5
185	LINC01023	4.19	0	0
186	CEBPA	4.18	82	332
187	CDT1	4.17	4	11
188	ICAM4	4.17	35	100
189	HSH2D	4.17	4	12
190	WFDC1	4.16	1	2
191	CASC15	4.16	4	5
192	NKX2-3	4.15	0	0
193	CKS2	4.14	0	0
194	BCAT1	4.14	3	3
195	ARHGAP31-AS1	4.14	3	5
196	SPINK4	4.14	54	69
197	HACD1	4.12	2	2
198	SOX5-AS1	4.12	3	3
199	LINC01150	4.10	5	19
200	MFSD2B	4.09	4	34
201	NPW	4.09	9	33
202	CAVIN2	4.08	0	0
203	CDK6	4.07	1	1
204	TFPI	4.07	54	106
205	STEAP3-AS1	4.05	3	5
206	PLD4	4.04	2	1
207	IL1B	4.04	15	58
208	ACY3	4.04	1	1
209	WNT8A	4.04	0	0
210	DNAAF2	4.02	2	2
211	C19orf38	4.01	0	1
212	PRAM1	4.01	84	448
213	FERMT1	4.00	8	7
214	AVPR1B	3.99	1	0
215	ADAM28	3.99	4	4
216	EGFL7	3.99	10	21
217	ZNRF1	3.98	0	0
218	TMEM217	3.97	105	362
219	KCNQ5	3.97	0	0
220	CBFA2T3	3.97	8	33
221	LINC00910	3.97	1	2
222	MYCN	3.95	1	1
223	IL12RB2	3.95	2	2
224	BTK	3.95	—	—
225	ITGA4	3.94	22	102
226	LINC00508	3.94	0	0
227	SLC17A9	3.94	1	1
228	ANKRD28	3.93	23	57
229	STAP1	3.93	0	0
230	CD244	3.92	32	60
231	C11orf96	3.92	3	18
232	RHOH	3.90	1	2
233	HOXA5	3.90	17	40
234	MALRD1	3.90	3	4
235	LINC02470	3.87	2	2
236	TPSAB1	3.87	1	3
237	LY6G6C	3.86	1	15
238	DOK3	3.86	11	20
239	ADGRF1	3.86	2	4
240	FOXD4	3.85	14	66
241	CD300LF	3.85	14	59
242	YRDC	3.85	0	0
243	CEACAM4	3.84	7	6
244	ASB9	3.84	—	—
245	LINC02142	3.84	2	2
246	ZNF492	3.83	—	—
247	BEX1	3.83	—	—
248	CTSG	3.83	3	2
249	CCDC188	3.83	4	5
250	PLAC8	3.82	2	2
251	MEG3	3.81	13	43
252	EFHC2	3.79	—	—
253	PAN3-AS1	3.79	0	0
254	TMEM212	3.78	2	48
255	GAB4	3.78	0	0
256	CENPU	3.78	9	17
257	SLC45A3	3.77	4	7
258	NPPC	3.76	2	2
259	SLC2A5	3.75	3	7
260	NCF4	3.75	7	38
261	SCARF1	3.75	72	152
262	IGF2BP1	3.74	6	13
263	SMIM6	3.74	2	4
264	TSPAN2	3.74	0	1
265	LINC01659	3.73	1	2
266	KLRF2	3.72	2	3
267	NREP	3.72	1	2
268	LST1	3.71	183	440
269	QRFP	3.71	0	0
270	RASGRP4	3.71	6	25
271	ACRBP	3.70	20	33
272	PRKG2	3.69	0	0
273	STK33	3.69	0	0
274	GPR12	3.69	0	0
275	MSMP	3.69	16	46
276	SLC9A7	3.69	—	—
277	HMGA1	3.69	15	37
278	TESPA1	3.69	6	11
279	SPATA32	3.68	18	35
280	SPNS2	3.68	1	0
281	GPR141	3.67	2	4
282	SLC27A2	3.67	7	17
283	FSCN1	3.66	0	0
284	MBOAT7	3.66	62	116
285	CLDN15	3.65	16	23
286	NRIP3	3.64	0	0
287	DPP10	3.64	0	0
288	CD37	3.64	8	15
289	UBE2R2-AS1	3.63	7	13
290	REXO5	3.63	4	4
291	AFF3	3.62	24	63
292	MFAP4	3.62	1	6
293	MATK	3.62	0	0
294	SLC12A5	3.62	15	97
295	TTC29	3.62	4	9
296	UMODL1	3.61	2	1
297	S100Z	3.61	15	55
298	TOX	3.61	1	2
299	B4GALT6	3.61	4	4
300	CCDC169	3.61	0	0
301	CCDC169-SOHLH2	3.61	0	0
302	EVA1B	3.60	16	55
303	GRIK5	3.60	1	2
304	STAC	3.60	0	0
305	CDCP1	3.60	5	5
306	C10orf55	3.59	6	20
307	SOCS2	3.59	24	64
308	JUP	3.59	17	24
309	ZNF521	3.58	3	5
310	ARHGAP22	3.57	5	5
311	DNAAF3	3.57	1	0
312	SYK	3.57	5	24
313	XIRP2	3.56	0	0
314	ANGPTL6	3.56	7	5
315	MYOSLID	3.56	0	1
316	SAMD13	3.55	0	0
317	SCML2	3.55	—	—
318	VAV3	3.54	7	11
319	ERAS	3.54	—	—
320	KLHL6	3.53	2	8
321	MECOM	3.53	14	56
322	DENND5B-AS1	3.52	2	2
323	MAP7	3.52	1	1
324	HTR1B	3.52	1	0
325	BEX2	3.51	—	—
326	LINC01132	3.50	12	28
327	LINC02168	3.50	—	—
328	CFAP126	3.49	9	14
329	IQSEC3	3.48	0	0
330	TYMS	3.47	5	5
331	LINC01870	3.47	0	0
332	LGALS9	3.47	—	—
333	CDK2AP1	3.46	23	95
334	TIE1	3.46	18	87
335	RGS1	3.46	7	12
336	HHEX	3.45	10	16
337	MEST	3.45	3	5
338	IL1RL1	3.45	43	110
339	ALOX12	3.44	14	33
340	LINC01122	3.44	4	5
341	GPSM1	3.43	51	202
342	FGF16	3.43	—	—
343	HMGB3	3.43	—	—
344	FOSB	3.42	10	20
345	MACC1	3.42	4	5
346	DAPK1	3.42	0	0
347	DMRTC1B	3.42	—	—
348	MIR155HG	3.42	0	0
349	LINC00114	3.41	20	39
350	FGF20	3.41	0	0
351	JUND	3.41	32	94
352	IQGAP2	3.40	26	84
353	DNMT3B	3.40	1	2
354	NAP1L3	3.40	—	—
355	PRSS21	3.39	2	2
356	MAK	3.38	3	3
357	SOST	3.38	37	203
358	IL12A	3.38	2	2
359	AFF2	3.38	—	—
360	SMPDL3B	3.38	6	46
361	OR4K17	3.37	—	—
362	REC8	3.37	6	9
363	MCTP2	3.37	2	3
364	MEIS1	3.36	2	4
365	RAB44	3.36	22	37
366	CCNA1	3.35	0	0
367	SPINT2	3.35	11	25
368	ZBTB8A	3.34	0	0
369	SRGN	3.34	34	60
370	MBOAT4	3.34	0	0
371	CCDC62	3.34	0	0
372	SYNGR1	3.33	0	1
373	FOS	3.33	3	3
374	ALDH1A1	3.33	5	5
375	INAFM2	3.33	8	20
376	ROBO4	3.32	3	3
377	DUSP10	3.31	0	0
378	CD33	3.31	18	76
379	PTGDR2	3.31	17	65
380	ADRB3	3.30	0	0
381	RAC3	3.30	6	21
382	ZBTB12	3.30	24	33
383	FIRRE	3.30	—	—
384	PCLAF	3.29	2	3
385	PLCB1	3.29	2	2
386	HTT-AS	3.29	22	47
387	TMEM44	3.28	0	1
388	GP9	3.28	0	0
389	ZNF667	3.27	0	0
390	DLK1	3.27	9	25
391	VSTM1	3.27	11	12
392	MIR181A1HG	3.27	13	57
393	ZP3	3.27	4	3
394	FAM171B	3.27	27	47
395	LAIR1	3.27	55	110
396	CCDC171	3.27	54	351
397	RAB32	3.26	2	1
398	SLC10A5	3.26	0	0
399	DEPTOR	3.25	9	15
400	SLC5A5	3.25	2	3
401	DNAH14	3.25	0	0
402	PCBP3	3.25	55	135
403	B3GNT5	3.25	0	0
404	TSPAN32	3.24	17	78
405	ICA1	3.24	0	0
406	TIGD3	3.24	2	10
407	ANKLE1	3.23	8	34
408	MEI4	3.23	0	0
409	KLF10	3.23	5	18
410	NRROS	3.22	9	29
411	CLGN	3.22	0	0
412	LINC02249	3.22	0	0
413	TTC24	3.21	25	63
414	CHST11	3.21	0	0
415	RAC2	3.21	7	38
416	SIGLEC10	3.21	4	5
417	ZSCAN1	3.20	0	0
418	TMEM163	3.20	0	0
419	FAM163A	3.19	0	0
420	SHISA2	3.18	0	0
421	ZPBP	3.17	61	161
422	SLITRK4	3.16	—	—
423	DNAH10	3.16	0	0
424	NEU4	3.16	0	0
425	RIPK2	3.16	5	5
426	PLA2G4A	3.15	5	7
427	INPP4B	3.14	1	1
428	NPM2	3.14	16	44
429	NSUN7	3.14	1	4
430	ARL11	3.13	1	0
431	LINC01215	3.13	5	18
432	KHDRBS2	3.13	3	3
433	CD74	3.13	13	14
434	NUDT10	3.13	—	—
435	CDCA7L	3.12	0	0
436	MAPK12	3.12	12	26
437	CLNK	3.12	9	15
438	SIGLEC15	3.12	1	13
439	CTSW	3.12	22	46
440	LYN	3.11	11	64
441	CD82	3.11	4	13
442	SYT1	3.11	2	2
443	HLA-DRB5	3.10	364	756
444	CAGE1	3.10	7	16
445	SLC24A3	3.10	0	0
446	SNX32	3.10	14	34
447	GMFG	3.10	1	1
448	CHRDL1	3.09	—	—
449	KIF18A	3.09	0	0
450	ZNF726	3.09	—	—
451	SNHG7	3.08	8	20
452	SNCA	3.08	7	8
453	MEX3B	3.08	2	1
454	EZH2	3.07	0	0
455	ITM2C	3.06	0	0
456	LPCAT2	3.06	3	6
457	MYOZ3	3.06	4	4
458	XKR3	3.05	—	—
459	BASP1	3.05	0	0
460	CLEC12A	3.05	41	41
461	MARVELD1	3.04	3	9
462	PHTF1	3.04	63	136
463	SLC24A5	3.04	—	—
464	LINC02050	3.04	0	0
465	CHRFAM7A	3.04	—	—
466	LDHAL6A	3.04	0	0
467	ACOXL	3.03	10	36
468	LINC01694	3.03	31	80
469	GNAI1	3.03	69	90
470	TTLL6	3.03	11	23
471	GBP4	3.03	2	2
472	CAPN11	3.03	7	18
473	PLEKHG4B	3.03	2	6
474	HLA-DRB1	3.02	565	1,192
475	RGL4	3.02	0	0
476	HSPA5	3.02	0	0
477	PDGFC	3.02	13	22
478	MAN1A1	3.01	8	10
479	SPDYE4	3.01	2	2
480	ICAM3	3.01	28	48
481	LAPTM5	3.01	16	38
482	IRF5	3.01	48	98
483	ACSM3	3.01	7	23
484	KCNQ1OT1	3.00	3	7
485	EBPL	3.00	12	40
486	MSI2	3.00	1	1
487	UBE2S	3.00	1	1
488	ATF3	3.00	8	26
489	HPGD	2.99	0	0
490	SOX12	2.99	1	2
491	HOXA10	2.98	9	12
492	LINC01970	2.98	6	21
493	ARL9	2.98	0	0
494	EAF2	2.98	9	34
495	NFKBIA	2.98	8	22
496	IGFBP7	2.98	21	47
497	USH1C	2.97	1	1
498	MLLT3	2.97	2	1
499	PLAGL1	2.96	21	51
500	LINC02284	2.96	0	0
501	NUDT11	2.96	—	—
502	OSGIN2	2.95	6	7
503	TBX10	2.95	0	0
504	KNL1	2.94	7	7
505	ZNF222	2.94	11	19
506	NR4A3	2.93	0	0
507	RNF125	2.93	5	4
508	SMIM10	2.92	—	—
509	FCER1A	2.92	34	50
510	DUSP1	2.91	12	46
511	PPP1R15A	2.91	44	83
512	GPSM2	2.91	1	1
513	WASF1	2.91	0	8
514	PTPN7	2.90	5	9
515	ST20-AS1	2.89	12	24
516	CDH26	2.89	0	0
517	HLF	2.89	15	33
518	RUNX1	2.89	52	65
519	SPN	2.89	4	17
520	NFKB1	2.89	57	125
521	VPS9D1-AS1	2.88	27	43
522	FGD5	2.88	11	61
523	HENMT1	2.88	1	1
524	DPY19L2	2.88	3	2
525	FAM53C	2.88	0	0
526	BCL7A	2.87	19	39
527	PRKAR2B	2.87	0	0
528	ZNF574	2.87	1	2
529	ELF1	2.87	33	104
530	DRC7	2.87	0	0
531	CABLES1	2.86	4	7
532	PMEPA1	2.86	7	64
533	CMBL	2.86	0	0
534	OR3A2	2.86	0	0
535	STMN1	2.86	0	0
536	ADGRG1	2.86	1	2
537	ZNF385C	2.86	2	18
538	KLHDC7B	2.86	5	36
539	SKIL	2.86	1	3
540	MFAP2	2.85	25	65
541	FAM216A	2.85	1	4
542	IGFBP7-AS1	2.85	20	47
543	CA9	2.85	16	48
544	DRAM1	2.85	33	37
545	LINC01521	2.85	4	27
546	GALNT14	2.84	5	11
547	LILRB2	2.84	89	145
548	ARHGDIB	2.84	3	8
549	NFKBIE	2.84	13	27
550	YBX3	2.84	3	4
551	TRIM24	2.84	0	0
552	RPS2	2.84	2	6
553	ALYREF	2.83	0	0
554	LINC00539	2.83	0	0
555	NPHP3-AS1	2.83	1	2
556	SLCO5A1	2.83	0	0
557	CD38	2.83	5	10
558	MTURN	2.83	3	5
559	RPS6	2.82	1	1
560	GSTM5	2.82	4	7
561	FAM224B	2.82	—	—
562	TRO	2.82	—	—
563	CYP4A22-AS1	2.82	15	19
564	CCNL1	2.81	13	23
565	LDLR	2.81	92	829
566	JAK3	2.81	6	8
567	HLA-DOA	2.81	225	407
568	PANX2	2.81	5	16
569	NPAS1	2.81	20	29
570	FAM169A	2.80	0	0
571	LINC01806	2.80	3	3
572	PAWR	2.80	4	4
573	MTMR6	2.80	0	0
574	NDST3	2.80	0	0
575	FAM224A	2.79	—	—
576	RILPL2	2.79	24	92
577	LINC00887	2.79	0	0
578	NFKBIZ	2.79	2	3
579	ELOVL7	2.79	1	1
580	STMN3	2.78	62	155
581	ZBED3	2.78	0	0
582	PLEK	2.78	27	52
583	S1PR4	2.78	13	44
584	LINC02550	2.77	0	0
585	PTPRD-AS1	2.77	1	0
586	SGIP1	2.77	0	1
587	TTYH3	2.77	13	33
588	PTX3	2.76	4	8
589	GNB4	2.76	2	6
590	SERPINB1	2.76	7	12
591	MREG	2.76	1	2
592	CACNB2	2.76	6	25
593	GNG4	2.76	1	1
594	ARIH1	2.76	0	0
595	NPY	2.76	0	0
596	RPL36A-HNRNPH2	2.75	—	—
597	C14orf178	2.75	0	0
598	ADRA2A	2.75	0	2
599	STK32B	2.75	0	0
600	ROBO3	2.75	2	2
601	PRC1	2.75	1	2
602	NPDC1	2.75	19	47
603	IL12A-AS1	2.75	0	0
604	RPL36A	2.74	—	—
605	MAP7D2	2.74	—	—
606	RPS18	2.74	17	39
607	RARA-AS1	2.74	12	41
608	RHPN1	2.73	30	73
609	RBPMS	2.73	31	78
610	ADGRE2	2.72	1	1
611	ZNF165	2.71	19	48
612	PTGS1	2.71	0	0
613	JUN	2.71	0	0
614	SMIM3	2.71	4	4
615	MEF2C	2.71	33	42
616	HLA-DPB1	2.71	293	562
617	PPP1R16B	2.71	4	3
618	IKZF1	2.71	58	153
619	MMP28	2.71	4	4
620	PIM2	2.71	—	—
621	DMRTC1	2.71	—	—
622	SERPINE2	2.71	6	14
623	C19orf84	2.71	2	6
624	GYPC	2.70	3	4
625	JAKMIP2	2.70	1	1
626	SAG	2.70	2	6
627	LINC01589	2.69	4	5
628	CFAP45	2.68	12	14
629	CD53	2.68	9	18
630	CNMD	2.68	1	1
631	DNTT	2.68	4	6
632	LINC01927	2.67	1	1
633	MEIG1	2.67	0	0
634	HLA-DPA1	2.67	287	545
635	RFWD3	2.67	2	12
636	HOXA7	2.66	11	15
637	LATS2	2.66	9	33
638	CA8	2.66	2	2
639	LOX	2.66	5	18
640	SCN11A	2.66	15	19
641	RNF217	2.65	2	2
642	SPINT1-AS1	2.65	7	7
643	MEF2C-AS1	2.64	41	67
644	LRFN4	2.64	6	7
645	NAT14	2.64	9	25
646	SULT1C4	2.64	2	3
647	KIF7	2.64	5	16
648	TBXAS1	2.64	5	10
649	CKAP2	2.64	1	4
650	MOV10L1	2.63	7	18
651	HOXA6	2.63	10	14
652	ARHGAP15	2.63	21	66
653	DUSP2	2.63	—	—
654	HLA-DQA1	2.62	608	1,232
655	FABP5	2.62	2	0
656	STAT5A	2.62	25	56
657	IPO11	2.62	0	0
658	FES	2.62	62	148
659	ZSWIM2	2.61	48	97
660	PRELID2	2.61	0	0
661	ELMO1	2.61	12	59
662	BEX3	2.61	—	—
663	IPO9-AS1	2.61	1	2
664	CSRNP1	2.60	16	48
665	MYADM	2.60	19	22
666	RCC1	2.59	3	2
667	ABCC1	2.59	4	14
668	MAFF	2.59	83	364
669	TGFBRAP1	2.59	1	3
670	ABCA13	2.58	0	0
671	LINC01971	2.58	11	15
672	UBE2E1-AS1	2.58	1	1
673	PTPRD	2.58	0	1
674	ZNF730	2.58	0	0
675	CCL25	2.58	0	0
676	CXorf58	2.58	—	—
677	LCP1	2.58	7	9
678	ZNF660	2.58	1	1
679	FAM222A	2.57	39	100
680	RPS4X	2.57	—	—
681	ZNF724	2.57	—	—
682	HOXB3	2.57	34	99
683	PAFAH1B3	2.57	0	0
684	PDZD8	2.57	0	0
685	PPP1R14B	2.57	10	22
686	MFNG	2.57	6	19
687	MORN1	2.56	10	54
688	SPIN4	2.56	—	—
689	ZSWIM6	2.56	1	0
690	RPL27A	2.56	5	9
691	TUBB4B	2.56	4	6
692	MYEF2	2.56	1	1
693	FBXO33	2.56	6	6
694	PROSER2	2.56	7	8
695	PCAT18	2.55	2	3
696	ZNF385D	2.55	1	2
697	C12orf57	2.55	0	0
698	FAR2	2.55	0	0
699	SLC25A29	2.55	14	37
700	WDR74	2.55	0	0
701	DSG2	2.55	4	5
702	APBB1IP	2.54	8	61
703	INPP5D	2.54	15	58
704	ATP2C1	2.54	0	0
705	TKT	2.54	21	71
706	RPL39	2.54	—	—
707	ANKRD13B	2.54	—	—
708	ETV6	2.54	5	13
709	CRISPLD1	2.54	0	0
710	SERPINI2	2.54	1	1
711	WASHC1	2.53	13	67
712	CCNG2	2.53	1	1
713	LINC01675	2.53	0	0
714	FAM81B	2.53	0	0
715	PTPRC	2.53	14	91
716	IGBP1	2.53	—	—
717	HELLS	2.53	4	6
718	RPS23	2.53	0	2
719	ZNF695	2.53	2	4
720	RGS2	2.53	0	0
721	SLA	2.52	6	26
722	NUCB2	2.52	6	5
723	MATN1	2.52	8	26
724	OR2C3	2.52	4	14
725	HARBI1	2.52	51	333
726	ZNF709	2.52	0	1
727	NAALADL1	2.52	0	0
728	SLC7A1	2.52	2	2
729	TMPO-AS1	2.52	2	3
730	ZIK1	2.52	0	0
731	CD302	2.52	13	43
732	EPHA1-AS1	2.52	8	16
733	SMO	2.52	3	10
734	LINC00506	2.51	1	0
735	RPS29	2.51	1	1
736	SMIM1	2.51	1	1
737	CARD9	2.51	51	204
738	SNHG19	2.51	8	24
739	CERS6	2.51	11	35
740	ARC	2.51	5	4
741	RAB34	2.51	—	—
742	STON2	2.51	0	0
743	STK17B	2.50	5	39
744	SIK1	2.50	5	13
745	MYL6B	2.50	0	0
746	KPNA2	2.49	2	4
747	STYK1	2.49	1	1
748	ACAP1	2.49	107	149
749	ISYNA1	2.49	57	136
750	ERICH6-AS1	2.49	0	0
751	RPS21	2.49	14	50
752	PHACTR1	2.49	7	11
753	FUT4	2.48	2	2
754	IMPG2	2.48	2	2
755	TBC1D16	2.48	7	24
756	SAMSN1	2.48	11	22
757	NDUFV2-AS1	2.48	1	3
758	BZW2	2.47	0	1
759	LETM2	2.47	0	0
760	DDX28	2.47	19	53
761	RUNX2	2.47	3	12
762	C6orf62	2.47	1	6
763	E2F5	2.46	1	1
764	ADA	2.46	12	21
765	HESX1	2.46	8	10
766	NDC80	2.45	0	0
767	TSPYL4	2.45	2	3
768	VAMP8	2.45	38	110
769	SLC39A8	2.45	55	116
770	HIPK1	2.45	72	153
771	MCM2	2.45	8	10
772	SP9	2.45	0	0
773	RPS3	2.45	0	0
774	MEIS1-AS2	2.44	0	0
775	ETV3	2.44	1	2
776	LIMD2	2.44	7	34
777	TSPYL2	2.44	—	—
778	ZFAS1	2.44	7	21
779	TUSC1	2.44	0	0
780	NR4A1	2.44	8	14
781	RAVER2	2.44	1	3
782	TAPT1	2.43	1	1
783	PNMT	2.43	25	75
784	HLA-DMA	2.43	226	330
785	RPLP0	2.43	3	7
786	PYGL	2.43	1	1
787	PTGES3L-AARSD1	2.43	0	0
788	ZCCHC3	2.43	0	0
789	DDN-AS1	2.43	6	10
790	PDRG1	2.42	3	7
791	LAG3	2.42	12	24
792	HEATR4	2.42	0	0
793	ADGRG6	2.42	3	8
794	NHLRC4	2.42	7	15
795	SLC12A9-AS1	2.42	6	13
796	ABO	2.42	185	251
797	LRMDA	2.41	13	14
798	ZNF99	2.41	0	0
799	PTGES3L	2.41	0	0
800	HTRA3	2.40	4	12
801	CCDC157	2.40	14	55
802	SSBP2	2.40	1	1
803	PELI2	2.40	0	0
804	CHEK1	2.40	1	1
805	POLQ	2.40	20	48
806	STK26	2.40	—	—
807	SMAD1-AS2	2.40	1	2
808	ACBD7	2.39	0	0
809	LRRN1	2.39	0	0
810	STK24-AS1	2.39	32	61
811	ZNF92	2.39	3	11
812	HIVEP2	2.39	3	4
813	HNRNPA1	2.39	13	14
814	PRDM11	2.39	6	15
815	PECAM1	2.39	18	52
816	RAB38	2.39	5	12
817	ESAM	2.39	2	2
818	PDE1A	2.38	0	2
819	ODF2-AS1	2.38	—	—
820	EFCC1	2.38	1	6
821	SYN1	2.38	—	—
822	SLC39A3	2.38	17	38
823	PCYT1B	2.38	—	—
824	ATP2A3	2.38	3	3
825	GNG11	2.38	3	3
826	ZBTB10	2.38	6	6
827	OIP5	2.38	0	0
828	EEF1G	2.37	10	27
829	GCNT1	2.37	0	0
830	SH3BP4	2.37	2	1
831	SRSF3	2.37	17	22
832	ETF1	2.37	1	1
833	HPDL	2.37	0	0
834	IER5	2.37	5	20
835	CD52	2.37	10	50
836	KLRG2	2.36	4	13
837	MPP1	2.36	—	—
838	SMOX	2.36	7	30
839	RPL38	2.36	4	9
840	SYTL1	2.36	13	29
841	PSME4	2.36	11	28
842	IL17D	2.36	2	45
843	RPL37	2.36	3	4
844	EEF1B2	2.35	6	9
845	PRDM16	2.35	0	0
846	PRTN3	2.35	31	78
847	FAM133A	2.35	—	—
848	KLF4	2.35	0	0
849	NFE2L3	2.35	1	1
850	FOXD4L5	2.35	—	—
851	NFATC2	2.35	8	23
852	OBSL1	2.35	15	52
853	SPDYE5	2.35	0	1
854	FXYD5	2.34	87	178
855	IKZF2	2.34	9	27
856	CAPN14	2.34	1	1
857	NEFH	2.34	0	0
858	TMEM200A	2.34	1	1
859	ABHD17B	2.34	0	0
860	MLLT11	2.34	11	42
861	NET1	2.34	10	17
862	RPS24	2.34	0	0
863	CCSER1	2.34	3	8
864	BMP2K	2.33	1	4
865	KCNE5	2.33	—	—
866	TIMP3	2.33	3	3
867	RPL31	2.33	0	0
868	RPS12	2.33	3	3
869	ZNF436-AS1	2.33	17	84
870	TSPAN33	2.33	3	8
871	TTC23L	2.33	1	5
872	LHX6	2.33	0	0
873	PNMA6A	2.33	—	—
874	RPL37A	2.33	6	10
875	IL2RG	2.33	—	—
876	CLEC2B	2.32	2	3
877	USP27X	2.32	—	—
878	TNFRSF21	2.32	1	2
879	MS4A4E	2.32	63	119
880	ANKRD33B	2.32	1	1
881	CXCL2	2.31	12	42
882	RBM15B	2.31	0	0
883	ID1	2.31	—	—
884	FBXO45	2.31	1	1
885	LEMD3	2.31	0	0
886	ADGRE3	2.31	2	5
887	BEND6	2.31	—	—
888	PXT1	2.31	18	23
889	DEPDC1B	2.31	0	0
890	ATP8B3	2.31	6	8
891	RPS5	2.31	1	0
892	PLAC1	2.31	—	—
893	CGREF1	2.30	7	15
894	RAB13	2.30	8	20
895	SLC22A8	2.30	—	—
896	SKIDA1	2.30	13	34
897	HCST	2.29	0	0
898	LINC02207	2.29	2	3
899	RPS3A	2.29	0	1
900	LPO	2.29	0	0
901	ZFX-AS1	2.29	—	—
902	RPL3	2.29	13	27
903	CREB3L4	2.29	8	21
904	NPAS3	2.29	10	34
905	IMPDH2	2.29	0	0
906	RPL34	2.29	1	4
907	TXNRD3	2.29	11	26
908	PIP5K1B	2.29	0	0
909	CIB2	2.29	10	27
910	UBALD2	2.28	3	4
911	HLA-DQB1	2.28	703	1,314
912	TBXA2R	2.28	5	9
913	ZNF704	2.28	1	0
914	LINC01088	2.28	4	10
915	COL24A1	2.28	8	16
916	PAQR5	2.28	0	0
917	TNFSF13B	2.28	1	0
918	IP6K2	2.28	5	16
919	ORAI3	2.28	0	0
920	LINC01012	2.28	0	0
921	ZNF439	2.28	0	0
922	SHF	2.28	5	29
923	FNDC10	2.28	11	36
924	ADGRA2	2.27	1	1
925	SGO1	2.27	0	0
926	DDAH2	2.27	146	231
927	BEND5	2.27	2	4
928	CD44	2.27	4	5
929	ZC3HAV1L	2.27	7	38
930	TNFRSF10C	2.26	20	51
931	ARMCX1	2.26	—	—
932	N4BP2	2.26	2	1
933	FOXO6	2.26	1	4
934	MYLIP	2.26	1	1
935	RPL15	2.26	0	0
936	MED26	2.26	3	12
937	USP51	2.26	—	—
938	DPF1	2.26	5	13
939	ADAM32	2.26	2	3
940	RPS20	2.26	11	38
941	SAMD10	2.25	16	34
942	ATG16L2	2.25	17	29
943	SLC38A5	2.25	—	—
944	FBXO41	2.25	0	0
945	SLC1A6	2.24	0	0
946	LINC02506	2.24	0	0
947	NTNG2	2.24	0	0
948	PDGFD	2.24	2	2
949	YOD1	2.24	11	11
950	KCNN4	2.24	27	66
951	ZBBX	2.24	0	0
952	ZBED4	2.24	4	7
953	KLF16	2.24	6	7
954	ULK4	2.24	4	12
955	SDE2	2.24	4	5
956	RNF24	2.24	2	2
957	KDM5B	2.23	1	1
958	CASP10	2.23	8	13
959	KDM6B	2.23	30	55
960	RPS9	2.23	51	100
961	GLS	2.23	0	0
962	ART5	2.23	1	4
963	MAP3K8	2.23	4	11
964	GSEC	2.23	16	15
965	LINC01686	2.23	10	14
966	DEPDC1	2.23	0	0
967	MIDN	2.23	5	8
968	OCIAD2	2.23	0	0
969	RPL10A	2.23	40	142
970	CXXC5-AS1	2.23	0	0
971	LINC01058	2.23	1	14
972	ME3	2.22	4	11
973	RASA4B	2.22	25	62
974	AADAT	2.22	1	3
975	LINC01545	2.22	—	—
976	ENDOU	2.22	5	34
977	CABYR	2.22	1	5
978	EMCN	2.22	10	11
979	TGIF2	2.22	3	12
980	PARVG	2.22	2	1
981	EPB41L4A-AS1	2.22	0	0
982	GPR27	2.22	2	2
983	STARD4-AS1	2.22	1	2
984	LINC01515	2.22	0	0
985	GADD45A	2.22	9	17
986	RPL26	2.22	4	5
987	CALCR	2.22	4	5
988	ABCB1	2.22	10	34
989	RASSF1-AS1	2.22	5	11
990	ADNP	2.21	0	0
991	BST1	2.21	2	2
992	RPL29	2.21	1	10
993	EEF1A1	2.21	6	8
994	SLCO4A1	2.21	2	2
995	DOCK2	2.21	1	1
996	RPL32	2.21	3	5
997	LINC01983	2.21	1	4
998	NECTIN2	2.21	217	1,214
999	MBOAT2	2.21	0	0
1000	GPR174	2.21	—	—