Evidence reports Cell populations FIB.interstitial DE genes Static evidence for AI interpretation. These reports provide data for prompting AI and are not intended as a human-facing reading interface. Please visit the Cell Browser , Trait Browser and Genome Browser for interactive browsing. Have fun exploring SCREATE!Association counts use unique genes with 01-High Priority evidence and unique cells in the authored Specific tier (not the IC-score significance threshold). Reverse counts list meta traits and individual traits separately; these are overlapping levels of evidence, not independent totals. Counts cover the full available catalogue, not the displayed rows or sampled UMAP. Unavailable profiles are excluded from reverse counts; a dash means unavailable or an ambiguous identity, not zero. The browser initially shows 50 rows; choose Rows to change this. Complete rows remain in the HTML, and ordinary page links expose any continuation pages for AI readers and crawlers.
FIB.interstitial: DE genes
How association tiers are defined — cell–trait and gene–trait SCREATE tier definitions supplied by the atlas curator. This methods note explains the prepared classifications; it does not recompute or change any report scores or tiers.
Cell–trait tiers Cell–trait links Identify cell types whose regulatory activity is associated with a trait’s genetic signal. Required for Specific or Relevant The ICE-CREAM score derived from the mean metacell Z score must be ≥ 5.39, with BOTH nominal and adjusted ICE-CREAM P values ≤ 0.05. Specific (Tier 1) Also meets all cell-set enrichment analysis (CSEA) criteria in at least one tested comparison: nominal P ≤ 0.05 AND adjusted P ≤ 0.05 AND normalized enrichment score (NES) ≥ 1, all in that comparison. This indicates that trait-associated activity is concentrated in this cell type relative to the tested background. Relevant (Tier 2) Meets the ICE-CREAM requirements but not the additional CSEA criteria. The cell type may share trait-associated activity with other cell types. Interpretation and report values CSEA is cell-set enrichment analysis, analogous to gene-set enrichment analysis but using sets of cells along a ranked list of ICE-CREAM scores. The eligibility score derived from the mean metacell Z score is not the displayed mean IC score. Do not infer a tier from the displayed mean, its descriptive Significance column, or a single CSEA summary value. Reports preserve prepared tiers; Other means an available association outside Specific/Relevant, and unavailable is not zero or proof of biological irrelevance. Meta traits and individual traits Use the prepared tier for the exact meta trait or individual trait. A meta trait’s Best child CSEA FDR is the lowest available child FDR, not a combined or meta-trait significance test. Its displayed mean child NES is descriptive, not a new CSEA test. These summaries must not be used to reconstruct or override the meta-trait tier. Gene–trait priorities (variant–tCRE–gene evidence) Variant–tCRE–gene links Candidate variants connect to genes through overlapping promoters or distal transcribed cis-regulatory elements (tCREs) linked to gene promoters by the Activity-by-Contact (ABC) model. Required genetic support The variant belongs to a purity-passing SuSiE credible set OR qualifies for Borzoi rescue. Borzoi rescue requires BOTH a variant-causality score ≥ 0.3 AND linkage disequilibrium with the lead variant of r² ≥ 0.2. Required cellular support The overlapping promoter has positive tCRE activity OR the distal element has a passing cell-specific ABC link to the gene, in a Specific or Relevant cell subtype (L1S) or fine-grained state (L2). BOTH genetic and cellular support are required for High or Medium priority. High priority Among records meeting both minimum requirements, High requires a genetic score ≥ 0.5 AND a Layer 1 correlation > 0.3 between tCRE activity and the trait’s cellular profile across cell subtypes. Medium priority Meets both minimum requirements but not one or both additional High thresholds. The genetic score is the higher of the SuSiE posterior inclusion probability (PIP) and the Borzoi variant-causality score. Same-record evidence and aggregation Each priority requires genetic and cellular evidence supporting the SAME variant–tCRE–gene record. Do not combine thresholds or evidence from different records to create a qualifying link. A gene receives the highest priority observed among its supporting records. A tCRE summary uses supporting records for that exact tCRE, not every trait of its linked genes. Separately displayed aggregate scores do not relax the same-record rule. Limits of interpretation A priority is candidate-association evidence, not proof of a causal variant, causal gene, causal cell type or treatment efficacy. Missing evidence is unavailable, not zero. MAGMA −log10(P), displayed credibility scores, cellular-context scores and G/C tier codes must not be substituted for these eligibility tests; use the provided records and their documented fields. Meta traits · Individual traits · Gene expression · DE genes DE log fold change is a different metric from mean expression and IC score. This is the complete available browser export, limited upstream to the top 1,000 genes per population; it is not an exhaustive genome-wide differential-expression result.
All 1,000 available exported DE genes
Browsers # Gene DE log fold change Meta traits (High Priority) Individual traits (High Priority)
1 LINC01661 22.06 — — 2 DCN 11.47 5 30 3 CFD 10.70 32 76 4 MGP 10.56 3 8 5 LUM 10.30 5 20 6 APOD 10.08 0 0 7 DPT 9.76 0 1 8 MFAP4 9.71 1 6 9 MYOC 9.50 6 19 10 KRT24 9.27 13 55 11 ADH1B 9.08 99 251 12 FBLN1 8.90 4 8 13 IGFBP6 8.62 2 2 14 COL1A2 8.61 19 39 15 MFAP5 8.58 — — 16 CXCL14 8.35 0 0 17 SPARCL1 8.35 74 301 18 PDGFRL 8.30 28 59 19 SERPINF1 8.26 91 185 20 PLAC9 8.26 19 33 21 FBLN2 8.26 6 13 22 TNFAIP6 8.24 2 12 23 SCARA5 8.23 17 28 24 GSN 8.23 10 25 25 C1R 8.21 2 4 26 MMP2 8.15 4 6 27 FBLN5 8.09 17 45 28 CILP 8.06 0 0 29 HTRA3 8.01 4 12 30 PI16 8.00 8 13 31 PRELP 8.00 6 11 32 C7 7.79 2 5 33 CCDC80 7.75 7 12 34 ISLR 7.74 28 62 35 SFRP4 7.73 12 39 36 SMOC2 7.71 3 11 37 SOD3 7.69 3 3 38 CXCL12 7.62 1 1 39 PNMA6E 7.58 — — 40 SFRP2 7.58 1 4 41 C1S 7.57 1 3 42 COL6A3 7.57 20 54 43 PODN 7.48 4 27 44 ITGBL1 7.46 1 0 45 PLA2G2A 7.43 3 13 46 ABI3BP 7.39 6 6 47 LRRN4CL 7.36 0 0 48 VIT 7.33 2 2 49 MXRA8 7.31 7 40 50 P2RX2 7.28 12 17 51 IGFBP7 7.28 21 47 52 OLFML3 7.24 72 147 53 COL3A1 7.19 3 5 54 PDGFRA 7.19 9 40 55 EFEMP1 7.18 35 109 56 TCF21 7.16 1 2 57 PCOLCE2 7.15 7 20 58 CLEC3B 7.15 5 5 59 COL1A1 7.14 9 15 60 LINC02438 7.13 0 0 61 PTN 7.10 0 0 62 GSTM5 7.07 4 7 63 SERPINA3 7.07 330 480 64 GPX3 7.05 9 17 65 COL8A1 7.03 4 14 66 COL6A2 7.03 34 82 67 NNMT 7.00 19 24 68 SERPING1 7.00 26 78 69 CCL2 6.99 3 12 70 VEGFD 6.90 — — 71 TIMP3 6.88 3 3 72 RARRES2 6.87 22 42 73 C3 6.86 23 35 74 F10 6.84 25 56 75 SCN7A 6.82 2 2 76 IGFBP5 6.82 6 11 77 FIBIN 6.82 1 9 78 BGN 6.81 — — 79 PCOLCE 6.81 19 63 80 CD34 6.68 24 109 81 FGF7 6.68 5 15 82 FXYD1 6.63 76 148 83 HSPB6 6.62 1 10 84 IGFBP4 6.60 28 80 85 BRS3 6.59 — — 86 MEDAG 6.53 0 0 87 IGF1 6.53 36 77 88 CST3 6.51 — — 89 SRPX 6.48 — — 90 OSR1 6.48 1 5 91 COL6A1 6.47 35 85 92 OLFML1 6.46 1 6 93 FAM180B 6.45 — — 94 PTGDS 6.41 3 2 95 CCL11 6.41 2 11 96 COL15A1 6.35 10 38 97 ADIRF 6.32 5 6 98 CTSK 6.32 91 236 99 CFH 6.31 68 103 100 ABCA8 6.31 83 140 101 ADH1C 6.31 133 303 102 ANGPTL5 6.30 3 6 103 CBLN4 6.29 1 7 104 CD248 6.28 2 3 105 ECM1 6.26 60 158 106 COL14A1 6.22 12 22 107 FMO2 6.22 15 16 108 GPNMB 6.20 2 6 109 CRISPLD2 6.19 18 52 110 CLEC14A 6.16 3 6 111 PLTP 6.16 18 36 112 RARRES1 6.15 2 7 113 C1QTNF2 6.12 0 0 114 LINC01140 6.09 1 4 115 MAMDC2 6.08 4 9 116 ASPN 6.08 23 53 117 MEG3 6.07 13 43 118 FAP 6.06 0 0 119 SSPN 6.03 10 13 120 ANGPTL1 6.03 6 26 121 LTBP1 5.99 27 75 122 CHRDL1 5.98 — — 123 OMD 5.97 22 51 124 SPARC 5.95 1 2 125 CCL26 5.95 1 5 126 CYP4B1 5.95 1 8 127 LHFPL6 5.95 1 3 128 LAMA2 5.94 1 0 129 HTRA1 5.94 21 46 130 CYGB 5.93 7 7 131 KERA 5.93 1 1 132 ITIH5 5.92 4 4 133 PLPP3 5.90 50 135 134 CDO1 5.89 5 17 135 LINC01082 5.88 20 49 136 SHISA3 5.85 2 3 137 DIO3OS 5.84 1 2 138 SFRP1 5.83 2 12 139 AGTR1 5.82 9 10 140 TAGLN 5.81 25 92 141 SSX2 5.81 — — 142 GGT5 5.81 4 5 143 NUPR1 5.80 22 50 144 PMP22 5.80 4 13 145 CRLF1 5.80 18 29 146 IL33 5.80 1 2 147 SHOX2 5.78 0 0 148 PRRX1 5.78 9 22 149 LINC-ROR 5.77 0 0 150 SSC5D 5.77 16 44 151 C1QTNF7 5.77 3 9 152 TFPI 5.76 54 106 153 NOVA1 5.76 0 0 154 FN1 5.76 29 100 155 EFHD1 5.76 2 7 156 FMOD 5.75 9 18 157 APOE 5.74 351 1,543 158 RNASE4 5.72 5 7 159 SERPINE2 5.72 6 14 160 BMP4 5.72 31 87 161 ANG 5.72 5 7 162 COL12A1 5.71 1 1 163 GFPT2 5.69 3 4 164 GEM 5.69 7 10 165 FXYD6-FXYD2 5.69 8 8 166 LINC01787 5.68 0 0 167 BMP5 5.68 4 4 168 XG 5.67 — — 169 TMEM176A 5.66 50 102 170 LRIT1 5.66 — — 171 CAVIN1 5.65 38 80 172 IGFBP3 5.64 17 93 173 ITGA11 5.62 1 2 174 GFRA1 5.62 1 3 175 SPON2 5.62 23 69 176 HMCN2 5.61 1 2 177 PAMR1 5.61 1 2 178 MRC2 5.60 14 64 179 GLT8D2 5.58 1 1 180 KLF4 5.58 0 0 181 THBS2 5.57 7 38 182 MEG8 5.57 7 22 183 FSTL1 5.57 1 1 184 CAPN6 5.55 — — 185 CES1 5.55 8 16 186 IZUMO1R 5.54 0 0 187 PENK 5.54 3 13 188 HAS1 5.53 37 49 189 PTGIS 5.53 2 4 190 EMILIN1 5.53 14 23 191 LARP6 5.52 3 2 192 EBF2 5.52 2 2 193 SDC2 5.52 1 3 194 EMP1 5.52 5 13 195 CAVIN3 5.51 0 0 196 DIO2 5.51 1 1 197 SULF1 5.49 2 3 198 MT1A 5.47 27 116 199 RCN3 5.47 60 188 200 MYL9 5.47 7 17 201 FKBP10 5.46 15 19 202 PTGFR 5.44 8 36 203 HAS2 5.43 5 13 204 ADAMTSL2 5.43 31 42 205 C16orf89 5.42 0 0 206 FAIM2 5.41 5 10 207 TMEM119 5.40 11 22 208 ACVRL1 5.39 18 37 209 TMEM176B 5.38 39 71 210 THBS4 5.38 5 20 211 HSPB8 5.36 0 0 212 LINC01638 5.36 1 2 213 DCLK1 5.35 0 0 214 MFAP2 5.35 25 65 215 AKAP12 5.35 4 13 216 CALD1 5.35 21 57 217 LHX9 5.34 0 1 218 LINC00968 5.34 4 14 219 HSD11B1 5.34 16 46 220 TMEM254 5.33 16 29 221 ABCA6 5.32 109 193 222 CADM3 5.32 2 15 223 MFGE8 5.32 17 46 224 AEBP1 5.32 4 12 225 MRGPRF 5.31 34 97 226 NHS-AS1 5.31 — — 227 OSR2 5.31 0 0 228 TWIST2 5.29 4 6 229 PROK1 5.28 0 0 230 FXYD6 5.28 8 8 231 GPRC5A 5.27 3 6 232 NEGR1 5.26 5 12 233 NPPC 5.26 2 2 234 PLXDC1 5.25 1 3 235 FST 5.25 15 35 236 ELN 5.24 15 47 237 LOX 5.23 5 18 238 PTGES 5.23 5 10 239 CDH19 5.22 0 0 240 ANGPTL2 5.22 6 16 241 CLEC11A 5.21 0 0 242 SGCE 5.21 2 4 243 LTBP4 5.21 57 146 244 HSPB2-C11orf52 5.21 11 30 245 HSPB2 5.21 11 30 246 RGMA 5.21 3 4 247 ADAM33 5.20 20 42 248 SELENOP 5.20 3 4 249 MAP1LC3C 5.19 0 0 250 SERPINA5 5.19 359 512 251 TRIL 5.18 3 4 252 LINC01066 5.18 — — 253 SRPX2 5.18 — — 254 TMEM215 5.18 3 7 255 SLPI 5.17 33 63 256 TMEM100 5.17 0 4 257 GPC3 5.17 — — 258 A4GALT 5.15 8 37 259 C11orf96 5.14 3 18 260 RSPO3 5.14 29 81 261 ELANE 5.14 31 86 262 OSTN 5.13 2 3 263 ABCA10 5.11 96 171 264 COLEC12 5.11 15 23 265 SLC14A2-AS1 5.10 1 1 266 EMP2 5.10 14 22 267 CYP1B1 5.10 4 15 268 CYBRD1 5.09 21 56 269 PGF 5.09 2 2 270 FHL1 5.08 — — 271 BCHE 5.08 2 2 272 LINC00517 5.08 0 0 273 CBR3 5.08 1 5 274 NXPH3 5.07 3 9 275 PDGFRB 5.06 11 25 276 KDELR3 5.05 7 15 277 SLIT3 5.04 6 23 278 MGST1 5.04 2 1 279 PLA2G5 5.03 3 12 280 NOX4 5.02 9 56 281 COX7A1 5.02 2 5 282 IFI27 5.01 332 479 283 IGSF10 5.01 3 11 284 ABCB5 5.01 3 4 285 LOXL1 5.01 52 110 286 PROCR 5.00 39 86 287 NR2F1 5.00 0 0 288 LINC01081 4.99 17 44 289 ACKR3 4.99 2 4 290 STEAP4 4.98 0 0 291 ANGPTL7 4.98 0 0 292 OAF 4.97 9 18 293 SVEP1 4.97 1 1 294 FOXF1 4.96 24 70 295 VCAN 4.96 11 255 296 IGF2 4.96 43 132 297 EFEMP2 4.95 50 111 298 PID1 4.95 8 10 299 TCEAL7 4.94 — — 300 PLAT 4.94 — — 301 AKR1C1 4.94 23 57 302 FBN1 4.93 21 79 303 S100A13 4.92 8 14 304 MMP27 4.92 4 4 305 GNG11 4.92 3 3 306 RAMP2 4.91 8 18 307 PPIC 4.91 5 11 308 MT1M 4.90 29 70 309 EBF1 4.89 13 22 310 PDPN 4.87 1 9 311 ABCA9 4.86 102 179 312 KAZALD1 4.86 5 7 313 RERG 4.85 5 14 314 RSPO1 4.85 1 5 315 LINC02202 4.85 10 13 316 CERCAM 4.84 0 0 317 ALDH1A1 4.83 5 5 318 MATN2 4.83 6 10 319 NDN 4.82 — — 320 FAM162B 4.82 1 6 321 EPHX1 4.82 4 4 322 SUSD2 4.82 2 2 323 RET 4.82 5 4 324 COL6A5 4.80 0 0 325 GDF10 4.79 0 0 326 CEBPD 4.79 3 10 327 MMP19 4.79 0 0 328 PANDAR 4.77 — — 329 OLFML2B 4.77 9 18 330 SPRY1 4.77 2 3 331 SCRG1 4.76 0 2 332 TGFB1I1 4.76 6 16 333 GPX8 4.76 8 21 334 LPAR1 4.74 2 5 335 MAP1B 4.74 0 0 336 ADAMTS5 4.72 12 23 337 AKR1C2 4.72 12 28 338 XPNPEP2 4.71 — — 339 COL5A2 4.71 17 35 340 TNXB 4.71 153 526 341 MAFB 4.70 4 11 342 COMP 4.69 6 12 343 FRZB 4.69 2 7 344 ADAMTS2 4.68 9 25 345 WIF1 4.68 0 0 346 LVRN 4.68 2 4 347 CHRDL2 4.67 2 3 348 MEOX2 4.66 6 27 349 C1QTNF3 4.66 1 1 350 GLP2R 4.66 0 0 351 CALCRL 4.65 53 105 352 LTBP2 4.64 7 28 353 PLAU 4.64 21 55 354 KCNE4 4.64 2 2 355 SPOCK1 4.63 0 0 356 LMX1A 4.63 0 0 357 RND3 4.62 0 5 358 PCDH18 4.62 0 5 359 FGF16 4.62 — — 360 GAS1 4.61 0 0 361 VASN 4.61 28 75 362 TIMP1 4.60 — — 363 KIAA1210 4.60 — — 364 DPYSL3 4.60 1 1 365 LAMA4 4.60 10 12 366 ZNF280A 4.59 0 0 367 SLC16A4 4.58 0 0 368 PRDM6 4.58 7 15 369 DDR2 4.58 2 2 370 GALNT16 4.58 5 8 371 ECM2 4.55 27 58 372 LINC01091 4.55 1 2 373 SGCA 4.55 6 10 374 ADAMTSL3 4.53 5 16 375 SAMD11 4.53 8 25 376 FAM43B 4.51 10 20 377 CCL19 4.50 0 0 378 CPE 4.49 1 1 379 DNM3OS 4.48 0 0 380 CRYAB 4.47 20 64 381 TMEM59L 4.47 16 25 382 NGF 4.46 1 2 383 CNRIP1 4.46 26 38 384 ADM 4.45 22 57 385 BMPER 4.45 0 0 386 NTRK2 4.45 7 9 387 CLSTN2 4.45 0 0 388 LAMC3 4.45 0 0 389 EGFR 4.44 10 11 390 BOC 4.43 4 6 391 ID4 4.43 6 17 392 HAS2-AS1 4.42 5 13 393 RASD1 4.42 20 56 394 THY1 4.41 8 20 395 TMEM98 4.40 2 2 396 C1QTNF1 4.40 5 9 397 MXRA5 4.40 — — 398 NFIA-AS2 4.39 0 0 399 FAM180A 4.38 0 0 400 LGALS3 4.38 7 33 401 MMP23B 4.38 2 14 402 FOXF2 4.38 7 21 403 ANTXR1 4.38 1 3 404 FILIP1L 4.37 16 37 405 EFCAB9 4.37 4 12 406 ADAMTS1 4.36 8 15 407 CRABP2 4.36 3 4 408 MMP14 4.36 28 53 409 AXL 4.35 13 25 410 HOXC10 4.35 0 0 411 ZNF423 4.35 10 17 412 PROS1 4.35 0 0 413 MUSK 4.34 1 1 414 AGBL1-AS1 4.34 — — 415 OCM2 4.33 0 0 416 LGALS1 4.33 22 66 417 GALNT15 4.33 5 4 418 CPZ 4.32 11 38 419 LINC01133 4.32 6 11 420 TPPP3 4.31 25 66 421 SLC1A7 4.30 1 7 422 RBMS3 4.30 1 3 423 COLEC11 4.30 7 15 424 LINC02550 4.29 0 0 425 CLMP 4.29 3 5 426 INMT-MINDY4 4.29 6 12 427 LEFTY2 4.29 3 3 428 AGTR2 4.29 — — 429 SERPINE1 4.28 25 41 430 TBX18 4.28 0 0 431 COL5A1 4.28 4 10 432 PLSCR4 4.27 0 0 433 OGN 4.27 8 17 434 ID3 4.26 4 9 435 RAB3IL1 4.26 25 205 436 LINC01228 4.26 0 0 437 PCDHGC3 4.25 0 0 438 APCDD1L 4.25 0 0 439 HIC1 4.24 36 105 440 FGF18 4.23 4 6 441 CH25H 4.23 3 2 442 LINC00645 4.23 3 2 443 FNDC1 4.22 26 48 444 PTGER1 4.22 8 47 445 PDGFD 4.22 2 2 446 PTGIR 4.22 17 25 447 NDNF 4.21 0 0 448 LGALS3BP 4.21 5 5 449 CTSL 4.21 2 3 450 TMEM45A 4.21 5 5 451 EPHA3 4.21 0 0 452 DKK3 4.21 2 4 453 TPM2 4.21 29 79 454 PDLIM4 4.20 171 263 455 FSTL3 4.19 6 5 456 CXCL1 4.19 1 2 457 KCNS3 4.19 0 1 458 G0S2 4.19 8 30 459 CCL21 4.19 1 2 460 APCDD1 4.18 1 2 461 LHX8 4.18 0 0 462 SLIT2 4.18 0 0 463 CLU 4.18 11 28 464 GAS6 4.17 6 25 465 ALDH1A3 4.16 1 4 466 SOX9 4.16 14 22 467 SELENOM 4.16 15 53 468 KRTAP19-3 4.16 — — 469 HMGCLL1 4.15 0 0 470 HNRNPCL1 4.15 — — 471 GSC 4.14 336 487 472 TMEM200B 4.13 1 3 473 EGR1 4.13 1 1 474 EDNRB 4.13 14 41 475 LAMB1 4.13 9 16 476 CHRD 4.13 2 5 477 INMT 4.12 2 5 478 CTSF 4.12 9 19 479 LAMC1 4.12 60 136 480 CAV1 4.12 15 135 481 HHIP-AS1 4.11 2 3 482 AOC3 4.11 17 45 483 SELENBP1 4.10 16 25 484 LINC01312 4.10 1 4 485 COL6A6 4.09 0 0 486 KIAA0408 4.08 3 3 487 LRRC15 4.08 0 0 488 PRG4 4.07 5 7 489 AMPH 4.06 3 4 490 PTX3 4.06 4 8 491 ADGRD1 4.06 2 3 492 FKBP7 4.06 0 0 493 MGARP 4.05 2 3 494 P4HA2 4.05 213 354 495 CPXM2 4.04 1 1 496 COL4A2 4.04 31 70 497 TSKU 4.03 9 19 498 PTHLH 4.02 0 0 499 DKK2 4.02 0 0 500 RBP1 4.01 1 0 501 APOL4 4.01 11 28 502 MME-AS1 4.01 0 0 503 F3 4.00 0 0 504 INHBA 4.00 0 1 505 ZNF503 4.00 1 2 506 TBX20 4.00 2 1 507 CFB 4.00 508 1,239 508 SCUBE2 4.00 1 1 509 BDKRB1 3.99 0 0 510 ANK2 3.99 0 0 511 CLIP3 3.99 1 1 512 LINC00519 3.99 0 0 513 TMEM108 3.98 0 1 514 PLBD1 3.98 4 7 515 COL4A1 3.98 38 107 516 PPL 3.98 2 3 517 TWIST1 3.97 1 1 518 LINC02381 3.97 10 19 519 ENG 3.96 9 25 520 RHOJ 3.96 2 6 521 CHPF 3.95 4 15 522 DMP1 3.95 — — 523 CHODL 3.94 0 0 524 FBXO17 3.94 11 19 525 OR10D3 3.94 — — 526 RAET1G 3.93 0 0 527 ITM2A 3.93 — — 528 CDC42EP2 3.92 0 0 529 FILIP1 3.92 2 1 530 VIM 3.92 32 102 531 ALDH1A2 3.92 72 576 532 S100A16 3.92 5 8 533 HOXA11 3.91 10 17 534 SERTAD4 3.90 2 5 535 LRP1 3.90 53 254 536 THBS1 3.90 7 22 537 ANOS1 3.90 — — 538 IFITM3 3.89 28 58 539 DAB2 3.89 39 81 540 FENDRR 3.89 17 46 541 PRRX2 3.89 4 7 542 CCDC89 3.88 2 1 543 NID1 3.88 6 7 544 RAI2 3.87 — — 545 SERTAD4-AS1 3.87 9 22 546 GAS1RR 3.86 0 0 547 CNN3 3.86 2 3 548 MME 3.86 2 2 549 CYP27A1 3.86 43 170 550 RTL3 3.85 — — 551 UCHL1 3.85 0 0 552 B3GNT9 3.84 16 33 553 SMIM10 3.84 — — 554 HOXC-AS1 3.84 4 7 555 RAB34 3.83 — — 556 LRRC17 3.83 1 1 557 KRTAP10-4 3.83 0 0 558 PAPPA 3.82 3 4 559 PDLIM3 3.82 2 4 560 BICC1 3.82 22 101 561 RASL11A 3.82 3 26 562 ADAMTS4 3.81 15 24 563 SNAI2 3.81 0 0 564 VWA1 3.81 6 25 565 EFS 3.81 7 111 566 TSPAN4 3.81 20 57 567 LINC01615 3.81 1 6 568 MAP1A 3.81 1 2 569 NDUFA4L2 3.80 31 179 570 TAC1 3.80 0 0 571 CSF1 3.80 5 9 572 COPZ2 3.79 25 92 573 MYC 3.79 0 0 574 LINC00644 3.79 1 2 575 MSX1 3.78 0 0 576 MOXD1 3.78 7 21 577 DIRAS3 3.77 1 1 578 LHCGR 3.76 0 0 579 FAM114A1 3.76 5 13 580 NT5E 3.76 0 0 581 RAMP2-AS1 3.76 7 17 582 GSTM3 3.76 6 9 583 LINC01798 3.74 6 7 584 KANK2 3.74 127 940 585 GULP1 3.74 28 52 586 MYHAS 3.74 0 0 587 TPBG 3.73 0 0 588 TUBB6 3.73 3 4 589 PTPRD-AS1 3.71 1 0 590 VGLL3 3.71 5 8 591 LINC00632 3.71 — — 592 TRIP10 3.71 8 26 593 TIMP4 3.70 52 199 594 APLNR 3.70 12 28 595 CCL13 3.69 2 11 596 STEAP1 3.69 7 30 597 LINC01116 3.69 6 23 598 BAMBI 3.69 3 4 599 LINC02308 3.69 0 0 600 HEYL 3.68 9 28 601 IER3 3.68 247 484 602 RASL12 3.68 1 1 603 AADACL2 3.68 0 0 604 ERRFI1 3.68 3 6 605 FKBP9 3.68 6 10 606 EHD2 3.68 3 8 607 NTRK1 3.67 3 4 608 LINC00603 3.67 0 0 609 TBX4 3.67 1 1 610 CMBL 3.67 0 0 611 SEMA3E 3.66 2 3 612 TNNT3 3.66 24 72 613 HOXA10 3.66 9 12 614 SH3D19 3.66 6 10 615 SERPINH1 3.66 22 57 616 S100A4 3.65 2 2 617 CNGA3 3.65 — — 618 ALX1 3.65 0 0 619 CREB3L1 3.65 51 329 620 PDCD1LG2 3.65 1 0 621 PRRG3 3.65 — — 622 ANGPTL4 3.65 66 465 623 LINC01750 3.65 1 0 624 HSPG2 3.64 47 92 625 PRR16 3.64 5 3 626 PALLD 3.64 6 11 627 EGFLAM 3.64 0 0 628 LINC01139 3.64 0 0 629 TLL2 3.64 8 18 630 HSPA12B 3.63 23 45 631 RAB23 3.63 — — 632 LINC01712 3.63 0 0 633 CD9 3.62 2 6 634 RHOBTB3 3.62 5 10 635 OLFM1 3.62 4 8 636 COLCA1 3.61 16 45 637 SIX2 3.61 0 0 638 IL6 3.61 13 38 639 FZD4 3.61 4 10 640 CXCL2 3.60 12 42 641 LINC01239 3.60 3 4 642 RNF112 3.60 1 1 643 SYDE1 3.60 1 1 644 ANGPT1 3.59 0 3 645 TCF4 3.59 9 17 646 RXRG 3.59 0 0 647 FGFR1 3.58 15 23 648 NRK 3.58 — — 649 STXBP6 3.58 3 2 650 NTM 3.57 1 1 651 CLIC2 3.57 — — 652 MSRB3 3.57 0 0 653 TMEM47 3.56 — — 654 LINC01779 3.56 2 1 655 MSC-AS1 3.56 0 0 656 ACTA2 3.56 5 5 657 UAP1 3.56 8 8 658 RFTN2 3.55 4 34 659 ASIP 3.54 0 0 660 EFCC1 3.54 1 6 661 ARL4D 3.54 14 29 662 ITGA8 3.53 1 5 663 SNHG18 3.53 0 0 664 AOX1 3.53 2 1 665 PALM 3.53 16 43 666 EVC2 3.53 1 0 667 LMO3 3.52 3 4 668 COL18A1 3.52 51 139 669 DLK1 3.51 9 25 670 PLEKHH2 3.51 19 44 671 ZDHHC1 3.51 22 54 672 TMEM221 3.51 10 10 673 S1PR3 3.51 3 7 674 WNT10B 3.50 4 7 675 SIX1 3.50 0 0 676 MAB21L1 3.50 0 0 677 DMRT3 3.50 8 27 678 GLIS2 3.49 27 78 679 SSX3 3.49 — — 680 NFATC4 3.49 23 68 681 P3H3 3.49 12 24 682 CD302 3.49 13 43 683 KITLG 3.49 5 6 684 C1QTNF5 3.49 8 19 685 WNT2 3.47 10 55 686 NTN4 3.47 6 10 687 TCEAL9 3.47 — — 688 FGF10 3.47 — — 689 KCNK15 3.47 12 19 690 ACKR4 3.47 10 22 691 FLRT2 3.46 1 9 692 CDC42EP4 3.46 2 4 693 VCAM1 3.46 0 0 694 NID2 3.46 7 17 695 A2M 3.46 — — 696 RUNX1T1 3.46 1 1 697 LINC00484 3.46 13 14 698 REM1 3.45 — — 699 TBX22 3.45 — — 700 RGR 3.45 0 0 701 SPON1 3.44 0 1 702 TNS2 3.43 24 99 703 COL16A1 3.43 6 12 704 PHLDB1 3.43 22 60 705 LINC01807 3.43 0 0 706 BHLHE22 3.42 0 0 707 SYTL4 3.42 — — 708 NPHS2 3.42 0 0 709 IL11RA 3.42 0 0 710 GNG12 3.41 13 26 711 TXNDC8 3.41 0 0 712 RGS16 3.40 5 5 713 TSHZ2 3.39 6 14 714 PXDC1 3.39 5 16 715 BST1 3.38 2 2 716 FKBP1C 3.38 4 4 717 IBSP 3.38 7 16 718 NEUROG1 3.37 1 1 719 MAFF 3.36 83 364 720 TRPC7-AS2 3.36 — — 721 BNC2 3.36 7 23 722 KREMEN1 3.35 6 23 723 IL15RA 3.35 0 0 724 CDKN1A 3.35 19 29 725 SNX21 3.35 10 26 726 DIO3 3.35 1 2 727 PDE1A 3.35 0 2 728 BHMT2 3.35 37 104 729 CDR1 3.35 — — 730 DBN1 3.34 18 31 731 HSD3B7 3.34 46 104 732 SPSB4 3.34 3 8 733 CST2 3.34 — — 734 ADAMTS16 3.34 0 0 735 TULP2 3.34 24 41 736 KCNK17 3.33 2 6 737 TM4SF1 3.33 2 6 738 FEZ1 3.33 4 4 739 LINC00377 3.33 0 0 740 AADACL4 3.33 1 0 741 ZNF385D 3.32 1 2 742 PAX1 3.32 0 0 743 PCDH9 3.32 0 0 744 IL17D 3.31 2 45 745 GPC4 3.31 — — 746 PARVA 3.31 0 0 747 HNMT 3.31 2 2 748 NKD2 3.31 10 34 749 ARMCX1 3.30 — — 750 HRCT1 3.30 18 74 751 PDK4 3.30 5 8 752 PRDM12 3.30 0 0 753 LINC01088 3.30 4 10 754 TSPAN8 3.30 4 5 755 ATF3 3.30 8 26 756 MASP1 3.29 12 17 757 HOXD-AS2 3.29 12 47 758 AK1 3.29 7 16 759 CREB5 3.29 18 72 760 SEMA3B 3.29 11 28 761 PHYHD1 3.29 15 29 762 MIR99AHG 3.29 3 9 763 PITX1 3.28 1 2 764 MMP3 3.28 0 0 765 PLOD1 3.28 15 25 766 NFIA 3.28 7 14 767 PABPC5 3.27 — — 768 IL34 3.27 3 1 769 ARHGEF25 3.27 15 52 770 CCDC74B 3.27 0 0 771 HOXD11 3.27 6 24 772 S100A6 3.26 3 4 773 TGFB2 3.26 5 13 774 PLS3 3.26 — — 775 TMEM92-AS1 3.26 1 4 776 PTMS 3.26 15 37 777 RIPOR3 3.25 4 10 778 PDE5A 3.25 5 5 779 NTF3 3.25 0 0 780 RSPO4 3.25 0 0 781 BICRA-AS1 3.24 1 2 782 ARHGAP22 3.23 5 5 783 HSD11B2 3.23 24 69 784 SCARA3 3.23 16 40 785 CNTFR 3.23 0 0 786 SPRR2F 3.23 0 0 787 AKR1C3 3.22 59 224 788 HAAO 3.22 16 23 789 KCNJ8 3.22 4 14 790 CNTN4 3.22 0 1 791 PCGF2 3.22 0 2 792 EMX2 3.21 4 10 793 ARHGAP20 3.21 0 0 794 CCDC8 3.21 12 37 795 NPDC1 3.21 19 47 796 NAA11 3.21 0 2 797 PTGS2 3.21 2 4 798 TRIM47 3.21 58 138 799 FAM110B 3.20 0 0 800 LPAR4 3.20 — — 801 NR2F1-AS1 3.20 9 16 802 MSC 3.20 0 0 803 FMO3 3.20 16 19 804 MUSTN1 3.20 81 386 805 ANXA2 3.20 8 11 806 HGF 3.19 66 85 807 LINC02454 3.19 14 44 808 TPST1 3.18 3 3 809 GATA5 3.18 5 13 810 HOTAIR 3.18 0 0 811 CTHRC1 3.18 0 0 812 TMEM35A 3.18 — — 813 PLAUR 3.18 34 60 814 CCDC74A 3.18 0 0 815 LINC01354 3.17 1 5 816 PCDH8 3.17 0 0 817 LINC01257 3.17 0 2 818 SPSB1 3.17 20 38 819 ANXA1 3.17 2 2 820 AR 3.17 — — 821 PAGE4 3.16 — — 822 PTGFRN 3.16 8 20 823 FOSB 3.16 10 20 824 KIAA1755 3.16 6 11 825 LMNA 3.16 18 37 826 CDC42EP5 3.16 1 1 827 HOXC4 3.16 5 3 828 SGCB 3.16 — — 829 RADIL 3.16 0 1 830 RGS11 3.15 21 47 831 COLGALT2 3.15 10 27 832 GAL3ST4 3.15 0 0 833 SOCS3 3.15 33 147 834 EPB41L2 3.15 1 1 835 C8orf34 3.15 0 0 836 TBX5-AS1 3.14 6 170 837 MEIS2 3.14 0 0 838 PKIG 3.14 10 20 839 APP 3.14 0 0 840 LINC00703 3.13 — — 841 TGFB3 3.13 3 14 842 CAMK2N1 3.13 1 3 843 RNF212 3.12 9 39 844 HOXC9 3.12 6 8 845 OSMR 3.12 2 5 846 NFIB 3.12 7 15 847 ABCC9 3.12 6 17 848 FERMT2 3.11 11 62 849 MSX2 3.11 0 0 850 LINC01117 3.11 12 46 851 GAS7 3.11 1 2 852 TMEM255A 3.11 — — 853 LINC02106 3.10 9 13 854 ADRB3 3.10 0 0 855 SEMA3C 3.09 69 90 856 VAT1 3.09 9 12 857 LINC00924 3.09 0 0 858 MT1E 3.09 20 37 859 NEXN 3.09 21 71 860 EBF3 3.08 1 1 861 LINC02435 3.08 1 2 862 TAS1R1 3.08 5 9 863 FERMT1 3.08 8 7 864 TGFBR3 3.07 15 26 865 LINC01315 3.07 7 9 866 AHNAK2 3.07 2 1 867 TBX18-AS1 3.07 — — 868 MRGPRE 3.07 0 0 869 RCN1 3.06 5 11 870 SOSTDC1 3.06 0 1 871 SLC39A2 3.06 1 3 872 LINC01028 3.06 0 0 873 AIF1L 3.06 0 0 874 LINC01914 3.06 7 54 875 GAP43 3.05 0 0 876 TRHR 3.05 0 0 877 LOXL2 3.05 13 42 878 DACT2 3.05 2 2 879 LINC00398 3.05 1 0 880 GPR83 3.05 0 0 881 PRICKLE1 3.05 1 2 882 EMX2OS 3.05 4 10 883 FNDC5 3.05 0 0 884 PTGS1 3.05 0 0 885 HES1 3.05 0 0 886 LINC02143 3.05 — — 887 STK32B 3.05 0 0 888 LINC01436 3.04 0 1 889 LURAP1L 3.04 1 1 890 BDKRB2 3.04 1 10 891 FAM163A 3.04 0 0 892 ADRA1B 3.04 1 1 893 SMPDL3A 3.03 1 1 894 FCGRT 3.03 65 213 895 SPR 3.03 0 0 896 CTBP1-AS 3.03 12 46 897 SLC16A2 3.02 — — 898 VASH2 3.02 0 0 899 CD68 3.02 33 81 900 THBD 3.02 0 0 901 ZNF703 3.02 0 0 902 ARHGAP29 3.02 1 0 903 FGL2 3.02 2 2 904 SHCBP1L 3.01 33 97 905 NAV1 3.01 12 34 906 LDB2 3.01 2 2 907 LAMB2 3.01 16 40 908 MEX3B 3.01 2 1 909 F2RL2 3.00 19 65 910 RAB31 3.00 2 5 911 ASAP3 3.00 16 78 912 BACE2 2.99 17 18 913 ARHGAP6 2.99 — — 914 GOLIM4 2.99 0 0 915 PLAGL1 2.99 21 51 916 SLITRK4 2.98 — — 917 SLC6A2 2.98 3 6 918 ROBO3 2.98 2 2 919 LINC00989 2.98 3 4 920 SPRR2G 2.98 0 0 921 NR4A1 2.98 8 14 922 PLPP7 2.98 1 1 923 CNTN1 2.98 0 0 924 TMEM54 2.98 0 1 925 CRIP2 2.97 0 0 926 SLC43A3 2.97 27 87 927 PHLDA3 2.97 16 23 928 SFTA1P 2.97 1 1 929 WNT11 2.97 1 1 930 MTUS1 2.96 39 97 931 CKB 2.96 18 40 932 COL4A4 2.96 12 28 933 NKX3-2 2.96 0 0 934 DNM1 2.96 2 3 935 C1orf21 2.96 1 0 936 RGS22 2.95 0 0 937 NOTO 2.95 0 0 938 SGCD 2.95 0 0 939 C1orf54 2.95 7 10 940 CHST7 2.95 — — 941 TBX2-AS1 2.94 25 110 942 FAM13C 2.94 0 0 943 LEUTX 2.94 0 0 944 C1QTNF4 2.94 — — 945 RAB32 2.94 2 1 946 CLDN11 2.93 0 0 947 TMEM204 2.93 9 18 948 ALDH2 2.93 51 130 949 ARC 2.93 5 4 950 FRMD6 2.93 1 3 951 CALHM2 2.93 7 15 952 LRP11 2.92 0 0 953 BPI 2.92 10 10 954 HLX-AS1 2.92 72 241 955 STEAP2 2.92 8 36 956 UGDH 2.92 14 26 957 CPEB1 2.91 1 1 958 SNX7 2.91 0 0 959 LINC01579 2.91 2 3 960 PLXDC2 2.90 10 22 961 VSTM4 2.90 7 18 962 NGFR 2.90 4 11 963 PHGDH 2.89 0 0 964 PRSS23 2.89 6 15 965 PRCD 2.88 6 7 966 CDHR4 2.88 0 0 967 DPEP1 2.88 44 67 968 C6 2.88 2 6 969 TCEA3 2.88 14 73 970 MDK 2.88 57 347 971 CPED1 2.88 6 14 972 EMID1 2.88 1 3 973 TRPA1 2.87 0 0 974 AFP 2.87 3 7 975 LINC01013 2.87 0 0 976 ST3GAL4 2.87 37 47 977 LINC00648 2.87 1 1 978 HOXA11-AS 2.87 9 13 979 LINC01817 2.87 0 0 980 LINC02087 2.87 7 15 981 TNFAIP8L3 2.87 1 3 982 HMCN1 2.87 5 7 983 OR51I2 2.87 1 1 984 LXN 2.87 0 0 985 LINC00578 2.87 0 0 986 PTPRS 2.86 0 2 987 RGS4 2.86 0 0 988 CSRP2 2.86 0 0 989 FOXS1 2.86 3 8 990 MT2A 2.85 10 12 991 LINC01805 2.85 0 0 992 PLA2G4A 2.85 5 7 993 F2R 2.85 19 53 994 PCDHB16 2.85 0 0 995 LIFR 2.85 0 1 996 TUSC1 2.85 0 0 997 EGR2 2.85 3 8 998 LAPTM4A 2.85 14 22 999 DLC1 2.84 24 63 1000 CRTAP 2.84 7 16