Evidence reports Cell populations ASPC.inflammatory DE genes Static evidence for AI interpretation. These reports provide data for prompting AI and are not intended as a human-facing reading interface. Please visit the Cell Browser , Trait Browser and Genome Browser for interactive browsing. Have fun exploring SCREATE!Association counts use unique genes with 01-High Priority evidence and unique cells in the authored Specific tier (not the IC-score significance threshold). Reverse counts list meta traits and individual traits separately; these are overlapping levels of evidence, not independent totals. Counts cover the full available catalogue, not the displayed rows or sampled UMAP. Unavailable profiles are excluded from reverse counts; a dash means unavailable or an ambiguous identity, not zero. The browser initially shows 50 rows; choose Rows to change this. Complete rows remain in the HTML, and ordinary page links expose any continuation pages for AI readers and crawlers.
ASPC.inflammatory: DE genes
How association tiers are defined — cell–trait and gene–trait SCREATE tier definitions supplied by the atlas curator. This methods note explains the prepared classifications; it does not recompute or change any report scores or tiers.
Cell–trait tiers Cell–trait links Identify cell types whose regulatory activity is associated with a trait’s genetic signal. Required for Specific or Relevant The ICE-CREAM score derived from the mean metacell Z score must be ≥ 5.39, with BOTH nominal and adjusted ICE-CREAM P values ≤ 0.05. Specific (Tier 1) Also meets all cell-set enrichment analysis (CSEA) criteria in at least one tested comparison: nominal P ≤ 0.05 AND adjusted P ≤ 0.05 AND normalized enrichment score (NES) ≥ 1, all in that comparison. This indicates that trait-associated activity is concentrated in this cell type relative to the tested background. Relevant (Tier 2) Meets the ICE-CREAM requirements but not the additional CSEA criteria. The cell type may share trait-associated activity with other cell types. Interpretation and report values CSEA is cell-set enrichment analysis, analogous to gene-set enrichment analysis but using sets of cells along a ranked list of ICE-CREAM scores. The eligibility score derived from the mean metacell Z score is not the displayed mean IC score. Do not infer a tier from the displayed mean, its descriptive Significance column, or a single CSEA summary value. Reports preserve prepared tiers; Other means an available association outside Specific/Relevant, and unavailable is not zero or proof of biological irrelevance. Meta traits and individual traits Use the prepared tier for the exact meta trait or individual trait. A meta trait’s Best child CSEA FDR is the lowest available child FDR, not a combined or meta-trait significance test. Its displayed mean child NES is descriptive, not a new CSEA test. These summaries must not be used to reconstruct or override the meta-trait tier. Gene–trait priorities (variant–tCRE–gene evidence) Variant–tCRE–gene links Candidate variants connect to genes through overlapping promoters or distal transcribed cis-regulatory elements (tCREs) linked to gene promoters by the Activity-by-Contact (ABC) model. Required genetic support The variant belongs to a purity-passing SuSiE credible set OR qualifies for Borzoi rescue. Borzoi rescue requires BOTH a variant-causality score ≥ 0.3 AND linkage disequilibrium with the lead variant of r² ≥ 0.2. Required cellular support The overlapping promoter has positive tCRE activity OR the distal element has a passing cell-specific ABC link to the gene, in a Specific or Relevant cell subtype (L1S) or fine-grained state (L2). BOTH genetic and cellular support are required for High or Medium priority. High priority Among records meeting both minimum requirements, High requires a genetic score ≥ 0.5 AND a Layer 1 correlation > 0.3 between tCRE activity and the trait’s cellular profile across cell subtypes. Medium priority Meets both minimum requirements but not one or both additional High thresholds. The genetic score is the higher of the SuSiE posterior inclusion probability (PIP) and the Borzoi variant-causality score. Same-record evidence and aggregation Each priority requires genetic and cellular evidence supporting the SAME variant–tCRE–gene record. Do not combine thresholds or evidence from different records to create a qualifying link. A gene receives the highest priority observed among its supporting records. A tCRE summary uses supporting records for that exact tCRE, not every trait of its linked genes. Separately displayed aggregate scores do not relax the same-record rule. Limits of interpretation A priority is candidate-association evidence, not proof of a causal variant, causal gene, causal cell type or treatment efficacy. Missing evidence is unavailable, not zero. MAGMA −log10(P), displayed credibility scores, cellular-context scores and G/C tier codes must not be substituted for these eligibility tests; use the provided records and their documented fields. Meta traits · Individual traits · Gene expression · DE genes DE log fold change is a different metric from mean expression and IC score. This is the complete available browser export, limited upstream to the top 1,000 genes per population; it is not an exhaustive genome-wide differential-expression result.
All 1,000 available exported DE genes
Browsers # Gene DE log fold change Meta traits (High Priority) Individual traits (High Priority)
1 CFD 11.17 32 76 2 CXCL14 11.00 0 0 3 LUM 10.62 5 20 4 DCN 10.58 5 30 5 MGP 10.57 3 8 6 APOD 10.51 0 0 7 PLA2G2A 9.75 3 13 8 DPT 9.32 0 1 9 MFAP4 9.22 1 6 10 CXCL12 9.18 1 1 11 GPC3 9.03 — — 12 SRPX 8.73 — — 13 MFAP5 8.52 — — 14 MT1A 8.48 27 116 15 ADH1B 8.47 99 251 16 SERPINF1 8.41 91 185 17 IGFBP6 8.34 2 2 18 TNFAIP6 8.33 2 12 19 CCDC80 8.32 7 12 20 SOD3 8.27 3 3 21 C1R 8.21 2 4 22 MT1M 8.20 29 70 23 MYOC 8.10 6 19 24 NNMT 8.07 19 24 25 EFEMP1 8.06 35 109 26 FGF7 7.87 5 15 27 PLAC9 7.87 19 33 28 C1S 7.81 1 3 29 CCL19 7.79 0 0 30 THY1 7.75 8 20 31 IGFBP4 7.74 28 80 32 ISLR 7.67 28 62 33 PDGFRL 7.64 28 59 34 GSN 7.64 10 25 35 OLFML3 7.60 72 147 36 SFRP2 7.59 1 4 37 FBLN5 7.49 17 45 38 FBLN1 7.48 4 8 39 MXRA8 7.46 7 40 40 CLEC3B 7.43 5 5 41 GPX3 7.37 9 17 42 C3 7.33 23 35 43 CCL2 7.33 3 12 44 CD248 7.32 2 3 45 COL1A2 7.30 19 39 46 GAL 7.28 6 12 47 PODN 7.18 4 27 48 COL3A1 7.11 3 5 49 COL6A3 7.09 20 54 50 AADAC 7.03 1 4 51 LINC01920 7.02 0 0 52 TNNT3 6.99 24 72 53 COL1A1 6.93 9 15 54 PTGES 6.93 5 10 55 XG 6.92 — — 56 CTSK 6.91 91 236 57 RARRES2 6.90 22 42 58 HSPB6 6.87 1 10 59 HP 6.85 120 301 60 CTHRC1 6.85 0 0 61 GGT5 6.82 4 5 62 LRRN4CL 6.81 0 0 63 PI16 6.80 8 13 64 PCOLCE 6.79 19 63 65 CXCL10 6.76 8 10 66 APOE 6.72 351 1,543 67 CHRDL1 6.71 — — 68 CFH 6.68 68 103 69 ITIH5 6.61 4 4 70 PRRX1 6.56 9 22 71 NTRK2 6.55 7 9 72 NOVA1 6.54 0 0 73 MMP2 6.47 4 6 74 FBLN2 6.44 6 13 75 SERPING1 6.44 26 78 76 ASPN 6.42 23 53 77 TMEM176A 6.42 50 102 78 CYP19A1 6.37 1 0 79 SPARC 6.36 1 2 80 GSTM5 6.35 4 7 81 F10 6.34 25 56 82 MGST1 6.34 2 1 83 PCOLCE2 6.33 7 20 84 MFAP2 6.33 25 65 85 ECM1 6.32 60 158 86 LHFPL6 6.29 1 3 87 MEDAG 6.28 0 0 88 GPNMB 6.27 2 6 89 COL6A2 6.26 34 82 90 STEAP1 6.25 7 30 91 CD34 6.24 24 109 92 TIMP3 6.22 3 3 93 IGF2 6.22 43 132 94 LINC01140 6.22 1 4 95 TWIST2 6.21 4 6 96 OLFML1 6.14 1 6 97 IGFBP7 6.12 21 47 98 SVEP1 6.09 1 1 99 BGN 6.09 — — 100 FXYD1 6.09 76 148 101 CHI3L1 6.07 9 14 102 VIT 6.05 2 2 103 PRELP 6.05 6 11 104 PDGFRA 6.05 9 40 105 PTX3 6.04 4 8 106 ALPL 6.03 11 20 107 HTRA3 6.03 4 12 108 TAGLN 6.02 25 92 109 GDF10 6.02 0 0 110 TMEM119 6.02 11 22 111 C7 6.02 2 5 112 CPXM1 6.00 3 19 113 IGF1 5.99 36 77 114 FABP4 5.99 3 1 115 OMD 5.92 22 51 116 COL6A1 5.91 35 85 117 DCLK1 5.89 0 0 118 IGFBP3 5.89 17 93 119 PLTP 5.89 18 36 120 CILP 5.88 0 0 121 RARRES1 5.85 2 7 122 ANGPTL4 5.83 66 465 123 TMEM176B 5.83 39 71 124 PLAU 5.82 21 55 125 RASD1 5.80 20 56 126 ABI3BP 5.78 6 6 127 SMOC2 5.77 3 11 128 AEBP1 5.77 4 12 129 FST 5.74 15 35 130 AKR1C2 5.73 12 28 131 RAMP2 5.72 8 18 132 CPZ 5.71 11 38 133 COL14A1 5.70 12 22 134 CST3 5.69 — — 135 AKR1C1 5.68 23 57 136 TNMD 5.65 — — 137 MRGPRF 5.64 34 97 138 APOC1 5.63 301 1,434 139 HSPB2-C11orf52 5.63 11 30 140 HSPB2 5.63 11 30 141 ADM 5.54 22 57 142 CHL1 5.54 0 0 143 COL12A1 5.53 1 1 144 NUPR1 5.53 22 50 145 CRABP2 5.52 3 4 146 LINC01436 5.51 0 1 147 RNASE4 5.51 5 7 148 ANG 5.51 5 7 149 SLIT3 5.50 6 23 150 FAM180B 5.49 — — 151 CCL1 5.48 4 14 152 CYGB 5.47 7 7 153 ADIRF 5.46 5 6 154 FIBIN 5.44 1 9 155 ANGPTL2 5.43 6 16 156 OSR1 5.43 1 5 157 DUXA 5.42 0 0 158 PDPN 5.41 1 9 159 BDKRB1 5.38 0 0 160 PMP22 5.37 4 13 161 PLPP3 5.34 50 135 162 ELANE 5.34 31 86 163 PROCR 5.32 39 86 164 PTGFR 5.32 8 36 165 CPE 5.30 1 1 166 ACKR4 5.28 10 22 167 CAVIN1 5.28 38 80 168 TMEM254 5.28 16 29 169 CIDEC 5.27 0 0 170 VCAM1 5.27 0 0 171 SCARA5 5.26 17 28 172 SRPX2 5.26 — — 173 DIO3OS 5.25 1 2 174 FGF10 5.25 — — 175 HTRA1 5.25 21 46 176 IFI27 5.25 332 479 177 CAV1 5.24 15 135 178 IL33 5.24 1 2 179 CLU 5.23 11 28 180 CFB 5.22 508 1,239 181 CALD1 5.22 21 57 182 MYL9 5.21 7 17 183 POSTN 5.21 0 0 184 S100A13 5.21 8 14 185 IGFBP5 5.21 6 11 186 PTGDS 5.21 3 2 187 CAVIN3 5.21 0 0 188 DIO3 5.21 1 2 189 DMRT3 5.20 8 27 190 SFRP4 5.19 12 39 191 LOX 5.19 5 18 192 EGFLAM 5.18 0 0 193 MT1X 5.18 6 6 194 FMOD 5.18 9 18 195 SSPN 5.18 10 13 196 GSC 5.18 336 487 197 ECM2 5.16 27 58 198 SELENOP 5.15 3 4 199 NGFR 5.11 4 11 200 ELN 5.11 15 47 201 RCN3 5.11 60 188 202 EPHX1 5.10 4 4 203 LINC00603 5.09 0 0 204 LAMA4 5.09 10 12 205 FSTL1 5.07 1 1 206 STEAP4 5.06 0 0 207 C1QTNF7 5.06 3 9 208 GLT8D2 5.04 1 1 209 SPON2 5.03 23 69 210 ABCA8 5.01 83 140 211 VEGFD 5.00 — — 212 XPNPEP2 4.97 — — 213 BMPER 4.95 0 0 214 MT2A 4.95 10 12 215 CYP7B1 4.95 0 0 216 S100A16 4.95 5 8 217 SERPINA3 4.94 330 480 218 RSPO3 4.94 29 81 219 PTGER3 4.93 0 0 220 FMO2 4.92 15 16 221 AGTR1 4.92 9 10 222 CXCL9 4.90 6 5 223 RBP5 4.90 0 0 224 C1QTNF5 4.89 8 19 225 LINC01914 4.89 7 54 226 MEST 4.87 3 5 227 LINC01423 4.86 2 1 228 C16orf89 4.85 0 0 229 COL5A2 4.84 17 35 230 GFPT2 4.84 3 4 231 TMEM37 4.83 6 11 232 LMO3 4.82 3 4 233 PPIC 4.82 5 11 234 COX7A1 4.80 2 5 235 NDN 4.80 — — 236 TFPI 4.78 54 106 237 C11orf96 4.78 3 18 238 THBS2 4.78 7 38 239 ALDH1A3 4.77 1 4 240 HOXC8 4.77 5 6 241 GPX8 4.77 8 21 242 EMILIN1 4.75 14 23 243 EMP1 4.75 5 13 244 PDGFRB 4.74 11 25 245 CLEC11A 4.74 0 0 246 ADAMTS2 4.73 9 25 247 ANGPTL1 4.72 6 26 248 GAS6 4.71 6 25 249 IFITM3 4.70 28 58 250 IL11RA 4.69 0 0 251 TNC 4.68 40 75 252 VCAN 4.67 11 255 253 ACVRL1 4.67 18 37 254 SELENOM 4.66 15 53 255 SERPINH1 4.66 22 57 256 PRSS23 4.66 6 15 257 HOXC9 4.66 6 8 258 SSC5D 4.64 16 44 259 ITM2A 4.64 — — 260 EFEMP2 4.64 50 111 261 EMX2OS 4.64 4 10 262 APOL4 4.63 11 28 263 OLFML2B 4.63 9 18 264 LGALS3BP 4.62 5 5 265 LGALS3 4.62 7 33 266 SERPINA5 4.62 359 512 267 LMOD1 4.62 34 89 268 EMP2 4.60 14 22 269 VASN 4.60 28 75 270 LINC02202 4.60 10 13 271 CNTFR 4.60 0 0 272 CDO1 4.59 5 17 273 FNDC4 4.57 488 1,610 274 KAZALD1 4.55 5 7 275 LINC00645 4.55 3 2 276 FMO1 4.55 4 2 277 A4GALT 4.55 8 37 278 PTGIR 4.55 17 25 279 CCL8 4.55 5 14 280 GEM 4.54 7 10 281 EBF1 4.54 13 22 282 C1QTNF1 4.54 5 9 283 CTSL 4.53 2 3 284 SGCE 4.53 2 4 285 LINC02126 4.52 0 0 286 SDC2 4.52 1 3 287 LINC01133 4.50 6 11 288 SNAI2 4.49 0 0 289 NOX4 4.48 9 56 290 PRRX2 4.47 4 7 291 TGFB1I1 4.46 6 16 292 PTGIS 4.46 2 4 293 GNG11 4.46 3 3 294 OGN 4.46 8 17 295 DAB2 4.45 39 81 296 PCDH18 4.45 0 5 297 NEGR1 4.45 5 12 298 MMP19 4.43 0 0 299 DIRC1 4.42 21 33 300 SIX1 4.42 0 0 301 TMEM45A 4.42 5 5 302 VIM 4.42 32 102 303 FKBP10 4.41 15 19 304 ABCA6 4.40 109 193 305 CRYAB 4.40 20 64 306 FAP 4.40 0 0 307 ASS1 4.38 1 2 308 MEG3 4.36 13 43 309 IL6 4.36 13 38 310 HOXD-AS2 4.35 12 47 311 LPAR1 4.35 2 5 312 KDELR3 4.34 7 15 313 CDC42EP4 4.33 2 4 314 PDLIM4 4.32 171 263 315 LINC01312 4.31 1 4 316 KCNK15 4.31 12 19 317 COL4A1 4.31 38 107 318 LINC02381 4.30 10 19 319 COL15A1 4.29 10 38 320 LGALS1 4.29 22 66 321 TSPAN4 4.28 20 57 322 INSRR 4.27 2 2 323 ADAM33 4.26 20 42 324 WNT2 4.26 10 55 325 CHI3L2 4.25 4 12 326 TWIST1 4.25 1 1 327 LARP6 4.25 3 2 328 MT1E 4.24 20 37 329 RGS16 4.24 5 5 330 ADH1C 4.24 133 303 331 TIMP1 4.24 — — 332 TMEM98 4.23 2 2 333 GPC4 4.23 — — 334 OSR2 4.22 0 0 335 CPXM2 4.22 1 1 336 PPL 4.21 2 3 337 IZUMO1R 4.21 0 0 338 MXRA5 4.20 — — 339 TPBG 4.20 0 0 340 LINC01116 4.18 6 23 341 LINC01239 4.17 3 4 342 SCARA3 4.17 16 40 343 LOXL1 4.16 52 110 344 CERCAM 4.16 0 0 345 TSHZ2 4.15 6 14 346 TPM2 4.15 29 79 347 CYP4B1 4.15 1 8 348 KRT222 4.15 13 56 349 ANK2 4.15 0 0 350 CXCL11 4.14 6 5 351 GFRA1 4.13 1 3 352 FHL1 4.13 — — 353 TRIML2 4.11 0 1 354 LAMA2 4.10 1 0 355 LINC01153 4.09 — — 356 WNT11 4.09 1 1 357 MRC2 4.09 14 64 358 ABCA9 4.09 102 179 359 CNRIP1 4.07 26 38 360 KCNJ15 4.06 18 18 361 FZD4 4.04 4 10 362 HAS1 4.04 37 49 363 TNXB 4.03 153 526 364 DBX2 4.03 0 0 365 SPRY1 4.02 2 3 366 ANGPT1 4.02 0 3 367 KRT12 4.01 — — 368 TRIP10 4.00 8 26 369 MFGE8 4.00 17 46 370 AKR1C3 4.00 59 224 371 EDNRB 3.99 14 41 372 SLPI 3.99 33 63 373 LINC01048 3.99 0 0 374 CD36 3.97 101 134 375 CLMP 3.97 3 5 376 CRISPLD2 3.96 18 52 377 FGF16 3.96 — — 378 CYBRD1 3.96 21 56 379 S100A4 3.95 2 2 380 SPARCL1 3.94 74 301 381 FSTL3 3.94 6 5 382 ANGPTL5 3.94 3 6 383 COMP 3.93 6 12 384 F3 3.93 0 0 385 LBP 3.93 6 9 386 EMX2 3.92 4 10 387 HRCT1 3.92 18 74 388 PLA2G5 3.92 3 12 389 HOXC-AS1 3.92 4 7 390 RGMA 3.91 3 4 391 MT1G 3.90 28 174 392 SHCBP1L 3.89 33 97 393 COLCA1 3.89 16 45 394 KCNE4 3.89 2 2 395 COL4A2 3.89 31 70 396 SMOC1 3.88 7 7 397 TPPP3 3.88 25 66 398 NRN1 3.88 5 4 399 LINC01426 3.86 7 17 400 CD302 3.86 13 43 401 TSKU 3.85 9 19 402 VGLL3 3.85 5 8 403 SLC7A10 3.84 65 311 404 SERPINE1 3.84 25 41 405 TNFAIP2 3.84 17 47 406 RAI2 3.84 — — 407 STEAP2 3.84 8 36 408 NT5E 3.83 0 0 409 PAMR1 3.83 1 2 410 ADAMTS5 3.82 12 23 411 HOXC10 3.82 0 0 412 HOXA10 3.81 9 12 413 BHLHE22 3.81 0 0 414 GPRC5A 3.80 3 6 415 FILIP1L 3.80 16 37 416 CBR3 3.79 1 5 417 BOC 3.78 4 6 418 PLBD1 3.77 4 7 419 PRG4 3.76 5 7 420 CSF1 3.75 5 9 421 NEXN 3.74 21 71 422 FGL2 3.74 2 2 423 MAP1B 3.74 0 0 424 RERG 3.74 5 14 425 PID1 3.74 8 10 426 ANXA2 3.73 8 11 427 SHOX2 3.73 0 0 428 HAS2 3.72 5 13 429 BICC1 3.72 22 101 430 ABCA10 3.71 96 171 431 SELENBP1 3.70 16 25 432 LRRC32 3.70 3 3 433 C2 3.70 61 83 434 TUBA8 3.69 7 8 435 S100A6 3.69 3 4 436 ICAM1 3.69 18 31 437 ABCC2 3.69 37 70 438 CTSF 3.69 9 19 439 ITGBL1 3.67 1 0 440 IL15RA 3.67 0 0 441 RAB34 3.66 — — 442 S100A10 3.66 5 10 443 AHNAK2 3.66 2 1 444 ANXA1 3.65 2 2 445 CDH11 3.65 1 5 446 HSD11B1 3.65 16 46 447 FGF10-AS1 3.65 — — 448 NPR1 3.64 6 10 449 TUBB6 3.64 3 4 450 CCL13 3.63 2 11 451 MME 3.62 2 2 452 DKK2 3.61 0 0 453 ID3 3.60 4 9 454 GSTM3 3.59 6 9 455 DDR2 3.59 2 2 456 MMP23B 3.58 2 14 457 FBXO17 3.57 11 19 458 KLF4 3.57 0 0 459 TRIM47 3.57 58 138 460 OAF 3.57 9 18 461 REM1 3.56 — — 462 EGR1 3.56 1 1 463 EHD2 3.55 3 8 464 SLC43A3 3.54 27 87 465 IGSF10 3.53 3 11 466 PHLDA3 3.53 16 23 467 FOS 3.52 3 3 468 FAM114A1 3.52 5 13 469 HSPA6 3.52 198 266 470 CNN3 3.52 2 3 471 C1GALT1C1L 3.52 3 14 472 OSMR 3.51 2 5 473 GALNT16 3.51 5 8 474 LINC01640 3.50 — — 475 CXCL1 3.49 1 2 476 MAP1A 3.49 1 2 477 FN1 3.49 29 100 478 LDB2 3.47 2 2 479 EBF2 3.47 2 2 480 HOXC4 3.47 5 3 481 CRNDE 3.46 0 0 482 FAM151A 3.46 0 11 483 SPOCK1 3.46 0 0 484 RAB3IL1 3.46 25 205 485 LINC01305 3.46 0 0 486 PLA2G4D 3.45 0 0 487 PARVA 3.45 0 0 488 DMRT2 3.45 6 11 489 MMP8 3.44 4 4 490 HSD3B7 3.44 46 104 491 ROR1-AS1 3.44 1 3 492 PRICKLE1 3.43 1 2 493 C1QTNF2 3.43 0 0 494 RND3 3.43 0 5 495 TSPAN15 3.41 35 53 496 LINC02176 3.40 10 29 497 SFRP1 3.40 2 12 498 ATF3 3.40 8 26 499 SPIN2A 3.40 — — 500 RBMS3 3.39 1 3 501 NR0B1 3.39 — — 502 EMCN 3.39 10 11 503 G0S2 3.39 8 30 504 HOXC6 3.38 9 9 505 FNDC1 3.38 26 48 506 CXCL2 3.37 12 42 507 KCNA1 3.36 0 0 508 ADAMTS12 3.36 1 1 509 ZNF503 3.36 1 2 510 MUSTN1 3.35 81 386 511 ADAM12 3.35 2 2 512 CYP26B1 3.35 5 6 513 CCL26 3.34 1 5 514 NXPH3 3.34 3 9 515 HNMT 3.34 2 2 516 TMEM200B 3.34 1 3 517 HILPDA 3.34 3 5 518 DBN1 3.34 18 31 519 UBD 3.33 16 15 520 BDKRB2 3.33 1 10 521 NRP1 3.33 9 18 522 ACKR3 3.33 2 4 523 RCN1 3.33 5 11 524 COLEC12 3.33 15 23 525 HSPG2 3.33 47 92 526 FKBP7 3.33 0 0 527 LAPTM4A 3.32 14 22 528 ALX4 3.32 0 1 529 NID2 3.32 7 17 530 LINC02319 3.31 2 5 531 LRP1 3.31 53 254 532 DNASE1L3 3.30 28 45 533 RASL12 3.30 1 1 534 CP 3.30 13 19 535 CITED1 3.30 — — 536 HSPA1A 3.30 81 205 537 IER3 3.29 247 484 538 S100A11 3.28 3 3 539 FGF18 3.28 4 6 540 PLSCR4 3.28 0 0 541 ALX1 3.28 0 0 542 FBN1 3.27 21 79 543 RTL8B 3.27 — — 544 LINC01915 3.27 1 1 545 FAM20A 3.26 34 62 546 HAS2-AS1 3.26 5 13 547 CYP1B1 3.26 4 15 548 SUSD2 3.25 2 2 549 LRP1-AS 3.25 25 147 550 CDC42EP1 3.25 12 29 551 CEBPD 3.25 3 10 552 CD40 3.24 4 18 553 TCEAL9 3.24 — — 554 SRGAP1 3.24 0 1 555 KCNE2 3.24 1 3 556 LMNA 3.23 18 37 557 TNFSF13B 3.23 1 0 558 LINC00605 3.22 8 14 559 CES1 3.22 8 16 560 ENG 3.22 9 25 561 CLIC2 3.22 — — 562 TPST1 3.22 3 3 563 CMBL 3.22 0 0 564 PDCD1LG2 3.21 1 0 565 PPARG 3.21 122 460 566 DPYSL3 3.21 1 1 567 CD68 3.21 33 81 568 LINC01779 3.20 2 1 569 EFS 3.20 7 111 570 CADM3 3.20 2 15 571 SMIM10 3.20 — — 572 IL17D 3.20 2 45 573 LEP 3.20 0 0 574 COL16A1 3.19 6 12 575 ID4 3.19 6 17 576 SERPINE2 3.19 6 14 577 LTBR 3.19 21 43 578 LINC02351 3.19 0 0 579 HSPB8 3.19 0 0 580 COPZ2 3.18 25 92 581 LVRN 3.17 2 4 582 FBLN7 3.16 2 3 583 C6orf132 3.15 24 122 584 MMP28 3.15 4 4 585 ADAMTSL1 3.14 2 2 586 PHYHD1 3.14 15 29 587 CDKN1A 3.14 19 29 588 SLC2A5 3.13 3 7 589 BST1 3.13 2 2 590 TUSC3 3.12 10 10 591 HOXA7 3.12 11 15 592 CA12 3.12 7 15 593 ADRA2A 3.12 0 2 594 MSC 3.12 0 0 595 PTMS 3.11 15 37 596 LPL 3.11 50 219 597 LRRC17 3.11 1 1 598 SRRM3 3.10 1 4 599 CDC42EP5 3.10 1 1 600 LINC01050 3.09 0 0 601 IL1R1 3.09 24 48 602 CDKN3 3.09 0 0 603 MMP14 3.09 28 53 604 TEAD2 3.09 1 2 605 EGFR 3.09 10 11 606 ZFHX4-AS1 3.09 0 0 607 RBPMS 3.08 31 78 608 SEMA3C 3.08 69 90 609 AIFM2 3.08 0 1 610 PCDHGC3 3.08 0 0 611 FGFR1 3.08 15 23 612 LINC00519 3.08 0 0 613 AOX1 3.08 2 1 614 FCGRT 3.07 65 213 615 AKAP12 3.07 4 13 616 INMT-MINDY4 3.06 6 12 617 CALHM2 3.06 7 15 618 DLC1 3.06 24 63 619 P4HA2 3.05 213 354 620 ASPA 3.05 1 1 621 CD276 3.05 13 27 622 LINC01894 3.04 1 1 623 BIN1 3.04 9 15 624 DLX3 3.03 5 13 625 PRR16 3.03 5 3 626 RAB13 3.03 8 20 627 MAP1LC3C 3.03 0 0 628 FKBP9 3.03 6 10 629 LINC01397 3.03 0 0 630 CDC42EP2 3.03 0 0 631 CCBE1 3.02 0 1 632 EGFL6 3.02 — — 633 AKR1B15 3.02 3 6 634 TNFRSF1A 3.02 22 43 635 ALDH1A1 3.02 5 5 636 PLEKHA4 3.01 32 66 637 PPP1R1A 3.01 0 4 638 LINC00484 3.01 13 14 639 MAFF 3.01 83 364 640 GNG12 3.01 13 26 641 LSP1 3.00 41 132 642 RUNX1T1 3.00 1 1 643 NFIA-AS2 3.00 0 0 644 LDLRAD2 3.00 20 33 645 MYC 3.00 0 0 646 ARC 2.99 5 4 647 PENK 2.99 3 13 648 LINC01091 2.99 1 2 649 TIMP4 2.99 52 199 650 EBF3 2.99 1 1 651 FAM162B 2.99 1 6 652 IFITM1 2.98 45 142 653 LIMA1 2.98 22 63 654 C1orf167 2.98 33 111 655 DEPTOR 2.98 9 15 656 IRX1 2.98 0 0 657 HMCN2 2.98 1 2 658 SPR 2.97 0 0 659 CREB3L1 2.97 51 329 660 LAMB2 2.96 16 40 661 GRM7 2.96 0 0 662 CDKN2C 2.96 0 0 663 CILP2 2.96 50 108 664 SEMA3A 2.96 47 59 665 AK1 2.96 7 16 666 ZDHHC9 2.95 — — 667 HOXD8 2.95 14 50 668 PROS1 2.95 0 0 669 PDK4 2.95 5 8 670 COL8A1 2.93 4 14 671 LINC01257 2.93 0 2 672 LGMN 2.93 6 6 673 ROBO3 2.93 2 2 674 FOXF2 2.92 7 21 675 MMP27 2.91 4 4 676 LOXL2 2.91 13 42 677 HAPLN3 2.91 8 19 678 SOCS3 2.91 33 147 679 BATF3 2.91 5 4 680 LMX1A 2.91 0 0 681 CA3 2.90 3 5 682 INMT 2.89 2 5 683 AGAP2-AS1 2.89 7 23 684 CD9 2.89 2 6 685 STMN3 2.89 62 155 686 LAMC1 2.89 60 136 687 ANPEP 2.89 13 24 688 LEFTY2 2.89 3 3 689 LINC01117 2.89 12 46 690 ARHGAP20 2.89 0 0 691 PKIG 2.88 10 20 692 CXCL6 2.88 1 1 693 IFIT3 2.87 7 8 694 SNX21 2.87 10 26 695 RGS22 2.86 0 0 696 MYO1B 2.86 3 10 697 MASP1 2.86 12 17 698 CD63 2.86 0 0 699 PDGFD 2.85 2 2 700 DNM3OS 2.85 0 0 701 LINC00575 2.85 0 0 702 MITF 2.85 3 5 703 CYB5R2 2.85 0 0 704 DOK5 2.84 — — 705 PLPP7 2.83 1 1 706 TP53I3 2.83 5 43 707 ENPP2 2.83 8 14 708 COL5A1 2.83 4 10 709 RIPOR3 2.82 4 10 710 HSD11B2 2.82 24 69 711 HOXA5 2.82 17 40 712 ACTA2 2.82 5 5 713 C1QTNF4 2.82 — — 714 MSX1 2.81 0 0 715 LINC01028 2.81 0 0 716 RAB7B 2.81 3 5 717 ABCB11 2.80 22 61 718 PLIN2 2.80 4 7 719 DRAM1 2.80 33 37 720 ANTXR1 2.80 1 3 721 SLC25A48 2.79 5 8 722 LINC00310 2.78 6 28 723 TCEAL7 2.78 — — 724 CLIP1-AS1 2.78 0 0 725 ADAMTS3 2.77 17 49 726 FKBP14 2.76 2 5 727 UAP1 2.76 8 8 728 IL34 2.76 3 1 729 GULP1 2.76 28 52 730 VAT1 2.76 9 12 731 CRTAP 2.76 7 16 732 TNFSF10 2.76 15 24 733 FAIM2 2.75 5 10 734 SLC1A3 2.75 0 0 735 BMP4 2.75 31 87 736 APOL1 2.74 8 21 737 IFNGR2 2.73 7 12 738 HES1 2.73 0 0 739 MSC-AS1 2.73 0 0 740 ATP8B4 2.72 7 22 741 PCDHB4 2.72 0 0 742 RCVRN 2.72 0 0 743 CYP11A1 2.72 19 29 744 OLFM1 2.72 4 8 745 CALHM3 2.72 4 14 746 EXOC3L4 2.72 38 45 747 COL5A3 2.72 4 8 748 SNHG18 2.72 0 0 749 CLDN11 2.71 0 0 750 GSTM1 2.71 1 1 751 HOXA3 2.71 20 38 752 MAB21L1 2.70 0 0 753 C1QL4 2.70 0 0 754 BASP1 2.70 0 0 755 BACE2 2.70 17 18 756 RAET1G 2.70 0 0 757 TNFRSF12A 2.69 1 1 758 PLXDC1 2.69 1 3 759 CDON 2.69 4 4 760 IDO1 2.69 0 0 761 LTBP4 2.69 57 146 762 CSF3 2.69 5 13 763 DCAF12L2 2.68 — — 764 FILIP1 2.68 2 1 765 HOXA9 2.67 13 44 766 NTNG1 2.67 0 0 767 LINC00648 2.67 1 1 768 ABCB5 2.67 3 4 769 SP9 2.67 0 0 770 PYCR1 2.66 2 1 771 RAB42 2.66 3 2 772 PTPRD-AS1 2.65 1 0 773 MEG8 2.65 7 22 774 CLIP3 2.65 1 1 775 ETV7 2.64 17 22 776 S100A3 2.64 0 0 777 MDK 2.64 57 347 778 CYB5A 2.64 26 35 779 SEMA3D 2.64 2 8 780 LMCD1 2.64 5 11 781 SULF1 2.64 2 3 782 NID1 2.63 6 7 783 GAS1RR 2.63 0 0 784 HOXA10-AS 2.63 10 13 785 TUBB3 2.63 13 31 786 SPHK1 2.63 1 6 787 SLC39A14 2.62 9 21 788 GALNT15 2.62 5 4 789 MSRB3 2.62 0 0 790 HIC1 2.62 36 105 791 PDLIM1 2.62 19 37 792 MC5R 2.62 0 0 793 ID1 2.62 — — 794 PTH1R 2.61 15 22 795 COL6A6 2.61 0 0 796 LINC01778 2.61 8 27 797 CYP27A1 2.61 43 170 798 NINJ2 2.61 15 54 799 PALLD 2.60 6 11 800 LINC01712 2.60 0 0 801 MAP7D3 2.60 — — 802 ZFP36 2.60 1 0 803 NQO1 2.60 2 4 804 ERRFI1 2.60 3 6 805 AMPH 2.60 3 4 806 LINC02172 2.59 0 0 807 TMEM233 2.58 0 0 808 BDH2 2.58 5 16 809 IFI16 2.58 9 21 810 RHOBTB3 2.58 5 10 811 TMEM100 2.57 0 4 812 LINC01276 2.57 1 2 813 FHL2 2.57 2 4 814 SOD2 2.56 29 53 815 ALDH1L2 2.56 0 0 816 NECTIN2 2.56 217 1,214 817 CCDC74A 2.56 0 0 818 C6 2.56 2 6 819 LINC01886 2.56 0 0 820 IFITM2 2.56 53 160 821 PLPP1 2.55 8 17 822 TCF4 2.55 9 17 823 SH3PXD2B 2.55 2 10 824 FAM180A 2.55 0 0 825 LINC01315 2.54 7 9 826 IFIT1 2.54 4 4 827 LY6E 2.54 0 0 828 NFIB 2.54 7 15 829 LINC01985 2.53 1 2 830 SLC22A11 2.53 3 11 831 CD151 2.53 20 58 832 ADGRD1 2.53 2 3 833 LINC01615 2.53 1 6 834 MARCKS 2.52 1 2 835 KCTD11 2.52 20 39 836 STOML3 2.52 0 0 837 DDAH2 2.52 146 231 838 GRINA 2.51 48 90 839 CPED1 2.51 6 14 840 C14orf180 2.51 0 1 841 MLXIPL 2.50 233 1,124 842 ARHGAP6 2.50 — — 843 SHISA4 2.50 20 62 844 PRDX4 2.49 — — 845 ZDHHC1 2.49 22 54 846 ARID5B 2.49 29 74 847 GAL3ST4 2.48 0 0 848 CRIP1 2.47 2 11 849 PTPRS 2.46 0 2 850 PABPC5 2.46 — — 851 WASF3 2.46 6 14 852 MAFB 2.46 4 11 853 PLA2R1 2.46 12 44 854 NPB 2.46 0 0 855 COCH 2.46 1 1 856 FAM228A 2.46 4 31 857 ANGPT4 2.46 0 0 858 GREM1 2.45 0 0 859 ITGA11 2.45 1 2 860 LINC01638 2.45 1 2 861 CCDC74B 2.45 0 0 862 NENF 2.45 14 43 863 ZNF385A 2.45 94 96 864 SLC29A1 2.45 7 16 865 GLI3 2.45 0 0 866 CKS1B 2.45 5 10 867 OCIAD1-AS1 2.45 0 0 868 OLFM2 2.45 2 4 869 SFTA1P 2.44 1 1 870 IGSF22 2.44 1 1 871 USP19 2.44 3 4 872 FOSL1 2.43 26 51 873 P3H3 2.43 12 24 874 VCAN-AS1 2.43 — — 875 RFX8 2.42 2 3 876 C17orf58 2.42 20 50 877 TBX18 2.42 0 0 878 PHGDH 2.42 0 0 879 DNM1 2.42 2 3 880 TCF23 2.42 3 6 881 CSRP2 2.42 0 0 882 BAG3 2.41 17 43 883 CKB 2.41 18 40 884 BEX3 2.41 — — 885 STOM 2.41 3 3 886 TYMP 2.41 15 62 887 PLP1 2.41 — — 888 ZC2HC1B 2.40 — — 889 OVOL1-AS1 2.40 1 1 890 PLAT 2.40 — — 891 GLB1L 2.40 3 20 892 MAP1LC3A 2.40 0 0 893 PITX2 2.40 0 0 894 PFN2 2.40 0 0 895 TMEM54 2.39 0 1 896 CHEK2 2.39 24 54 897 TMEM204 2.39 9 18 898 SECTM1 2.39 6 21 899 KLF14 2.39 0 0 900 CYB5R3 2.38 13 44 901 MIR99AHG 2.38 3 9 902 IL17RC 2.38 1 1 903 HSPA12B 2.38 23 45 904 GJA1 2.38 3 10 905 PRCD 2.38 6 7 906 CCDC146 2.38 4 6 907 UCHL1 2.37 0 0 908 PDE1B 2.37 1 4 909 PKDCC 2.37 23 83 910 AR 2.37 — — 911 TRIP6 2.37 16 52 912 PLPPR2 2.36 1 2 913 CPQ 2.36 1 3 914 SMIM3 2.36 4 4 915 RNF212 2.36 9 39 916 TGM4 2.36 0 0 917 CGREF1 2.35 7 15 918 CAPN6 2.35 — — 919 BMP1 2.35 25 61 920 C1orf54 2.35 7 10 921 KCP 2.35 17 44 922 FERMT2 2.34 11 62 923 WARS2-IT1 2.34 3 17 924 ARL14EPL 2.34 1 2 925 TSPAN3 2.34 14 27 926 JUNB 2.33 9 31 927 FAM110B 2.33 0 0 928 MPZL1 2.33 1 1 929 MATN2 2.33 6 10 930 NKPD1 2.33 4 4 931 CD44 2.32 4 5 932 LINC00632 2.32 — — 933 CATSPERZ 2.32 7 10 934 IGF2-AS 2.32 40 125 935 TMEM121 2.32 0 0 936 PCDHB7 2.31 0 0 937 BNC2 2.31 7 23 938 IL13RA1 2.31 — — 939 ALDH1B1 2.31 3 3 940 ZDHHC19 2.31 14 21 941 TUBB 2.31 165 310 942 MRGPRF-AS1 2.30 17 58 943 PLAGL1 2.30 21 51 944 ARMCX1 2.30 — — 945 HPSE2 2.30 3 5 946 LINC01686 2.30 10 14 947 MAOB 2.30 — — 948 CCDC8 2.30 12 37 949 ACOT1 2.29 0 0 950 NPDC1 2.29 19 47 951 NOX5 2.29 0 0 952 WDR86 2.29 4 7 953 FLRT2 2.29 1 9 954 IL32 2.29 3 5 955 CD59 2.29 5 8 956 GPX4 2.28 30 119 957 INAFM1 2.28 2 7 958 CYSTM1 2.28 11 14 959 IFT22 2.28 15 24 960 GPC1 2.28 5 8 961 SPSB1 2.28 20 38 962 FLG 2.28 0 0 963 LINC01230 2.27 1 3 964 EPB41L2 2.27 1 1 965 NRSN2 2.27 1 0 966 ASIP 2.27 0 0 967 CACNA2D1 2.27 61 83 968 HSPA1B 2.26 60 376 969 TMEM150C 2.26 1 1 970 AK4 2.26 3 3 971 BIRC7 2.26 7 8 972 LINC01711 2.26 — — 973 GAS1 2.26 0 0 974 C8orf88 2.26 0 0 975 SLC35G3 2.26 — — 976 CRLF1 2.26 18 29 977 CRIP2 2.25 0 0 978 TSPAN6 2.25 — — 979 TMEM220 2.25 0 0 980 CAB39L 2.25 1 3 981 SNX7 2.25 0 0 982 FRZB 2.25 2 7 983 SYDE1 2.24 1 1 984 ALDH2 2.24 51 130 985 FBLIM1 2.24 12 35 986 KIAA0408 2.24 3 3 987 ACADL 2.24 0 0 988 MOXD1 2.24 7 21 989 CKAP4 2.23 3 6 990 CNPY4 2.23 0 0 991 FMO3 2.23 16 19 992 TRIL 2.23 3 4 993 ABCC9 2.23 6 17 994 GADD45B 2.23 1 1 995 CMKLR1 2.23 2 12 996 FAM43B 2.23 10 20 997 EFHD1 2.23 2 7 998 LINC00398 2.22 1 0 999 GCSH 2.22 1 4 1000 GPR158 2.22 0 0