Evidence reports Cell populations ASPC.baseline DE genes Static evidence for AI interpretation. These reports provide data for prompting AI and are not intended as a human-facing reading interface. Please visit the Cell Browser , Trait Browser and Genome Browser for interactive browsing. Have fun exploring SCREATE!Association counts use unique genes with 01-High Priority evidence and unique cells in the authored Specific tier (not the IC-score significance threshold). Reverse counts list meta traits and individual traits separately; these are overlapping levels of evidence, not independent totals. Counts cover the full available catalogue, not the displayed rows or sampled UMAP. Unavailable profiles are excluded from reverse counts; a dash means unavailable or an ambiguous identity, not zero. The browser initially shows 50 rows; choose Rows to change this. Complete rows remain in the HTML, and ordinary page links expose any continuation pages for AI readers and crawlers.
ASPC.baseline: DE genes
How association tiers are defined — cell–trait and gene–trait SCREATE tier definitions supplied by the atlas curator. This methods note explains the prepared classifications; it does not recompute or change any report scores or tiers.
Cell–trait tiers Cell–trait links Identify cell types whose regulatory activity is associated with a trait’s genetic signal. Required for Specific or Relevant The ICE-CREAM score derived from the mean metacell Z score must be ≥ 5.39, with BOTH nominal and adjusted ICE-CREAM P values ≤ 0.05. Specific (Tier 1) Also meets all cell-set enrichment analysis (CSEA) criteria in at least one tested comparison: nominal P ≤ 0.05 AND adjusted P ≤ 0.05 AND normalized enrichment score (NES) ≥ 1, all in that comparison. This indicates that trait-associated activity is concentrated in this cell type relative to the tested background. Relevant (Tier 2) Meets the ICE-CREAM requirements but not the additional CSEA criteria. The cell type may share trait-associated activity with other cell types. Interpretation and report values CSEA is cell-set enrichment analysis, analogous to gene-set enrichment analysis but using sets of cells along a ranked list of ICE-CREAM scores. The eligibility score derived from the mean metacell Z score is not the displayed mean IC score. Do not infer a tier from the displayed mean, its descriptive Significance column, or a single CSEA summary value. Reports preserve prepared tiers; Other means an available association outside Specific/Relevant, and unavailable is not zero or proof of biological irrelevance. Meta traits and individual traits Use the prepared tier for the exact meta trait or individual trait. A meta trait’s Best child CSEA FDR is the lowest available child FDR, not a combined or meta-trait significance test. Its displayed mean child NES is descriptive, not a new CSEA test. These summaries must not be used to reconstruct or override the meta-trait tier. Gene–trait priorities (variant–tCRE–gene evidence) Variant–tCRE–gene links Candidate variants connect to genes through overlapping promoters or distal transcribed cis-regulatory elements (tCREs) linked to gene promoters by the Activity-by-Contact (ABC) model. Required genetic support The variant belongs to a purity-passing SuSiE credible set OR qualifies for Borzoi rescue. Borzoi rescue requires BOTH a variant-causality score ≥ 0.3 AND linkage disequilibrium with the lead variant of r² ≥ 0.2. Required cellular support The overlapping promoter has positive tCRE activity OR the distal element has a passing cell-specific ABC link to the gene, in a Specific or Relevant cell subtype (L1S) or fine-grained state (L2). BOTH genetic and cellular support are required for High or Medium priority. High priority Among records meeting both minimum requirements, High requires a genetic score ≥ 0.5 AND a Layer 1 correlation > 0.3 between tCRE activity and the trait’s cellular profile across cell subtypes. Medium priority Meets both minimum requirements but not one or both additional High thresholds. The genetic score is the higher of the SuSiE posterior inclusion probability (PIP) and the Borzoi variant-causality score. Same-record evidence and aggregation Each priority requires genetic and cellular evidence supporting the SAME variant–tCRE–gene record. Do not combine thresholds or evidence from different records to create a qualifying link. A gene receives the highest priority observed among its supporting records. A tCRE summary uses supporting records for that exact tCRE, not every trait of its linked genes. Separately displayed aggregate scores do not relax the same-record rule. Limits of interpretation A priority is candidate-association evidence, not proof of a causal variant, causal gene, causal cell type or treatment efficacy. Missing evidence is unavailable, not zero. MAGMA −log10(P), displayed credibility scores, cellular-context scores and G/C tier codes must not be substituted for these eligibility tests; use the provided records and their documented fields. Meta traits · Individual traits · Gene expression · DE genes DE log fold change is a different metric from mean expression and IC score. This is the complete available browser export, limited upstream to the top 1,000 genes per population; it is not an exhaustive genome-wide differential-expression result.
All 1,000 available exported DE genes
Browsers # Gene DE log fold change Meta traits (High Priority) Individual traits (High Priority)
1 CFD 11.67 32 76 2 LUM 11.34 5 20 3 DCN 11.24 5 30 4 MGP 11.02 3 8 5 CXCL14 10.82 0 0 6 APOD 10.66 0 0 7 DPT 10.18 0 1 8 MFAP4 10.10 1 6 9 GPC3 9.68 — — 10 CXCL12 9.56 1 1 11 ADH1B 9.35 99 251 12 MYOC 8.91 6 19 13 MFAP5 8.91 — — 14 IGFBP6 8.82 2 2 15 SOD3 8.69 3 3 16 SERPINF1 8.68 91 185 17 CCDC80 8.66 7 12 18 PLAC9 8.65 19 33 19 SRPX 8.59 — — 20 PDGFRL 8.57 28 59 21 SFRP2 8.55 1 4 22 ISLR 8.48 28 62 23 C1R 8.32 2 4 24 EFEMP1 8.31 35 109 25 OLFML3 8.29 72 147 26 MXRA8 8.27 7 40 27 FBLN5 8.19 17 45 28 GSN 8.08 10 25 29 FBLN1 8.07 4 8 30 C1S 7.99 1 3 31 XG 7.96 — — 32 PODN 7.92 4 27 33 CLEC3B 7.90 5 5 34 PLA2G2A 7.82 3 13 35 THY1 7.81 8 20 36 TNNT3 7.81 24 72 37 COL1A2 7.79 19 39 38 AADAC 7.69 1 4 39 CTSK 7.63 91 236 40 CD248 7.60 2 3 41 FGF7 7.60 5 15 42 GDF10 7.53 0 0 43 CTHRC1 7.51 0 0 44 IGFBP4 7.45 28 80 45 NOVA1 7.43 0 0 46 COL3A1 7.43 3 5 47 HSPB6 7.35 1 10 48 CHRDL1 7.34 — — 49 COL6A3 7.31 20 54 50 PRELP 7.31 6 11 51 GPX3 7.31 9 17 52 ASPN 7.29 23 53 53 PRRX1 7.25 9 22 54 GSTM5 7.24 4 7 55 CD34 7.23 24 109 56 COL1A1 7.20 9 15 57 CILP 7.16 0 0 58 RARRES2 7.12 22 42 59 NTRK2 7.12 7 9 60 F10 7.11 25 56 61 GPNMB 7.10 2 6 62 OLFML1 7.05 1 6 63 TMEM119 7.04 11 22 64 MMP2 7.04 4 6 65 LRRN4CL 7.03 0 0 66 PCOLCE2 7.02 7 20 67 C3 7.01 23 35 68 FBLN2 6.98 6 13 69 ITIH5 6.97 4 4 70 PCOLCE 6.96 19 63 71 ECM1 6.96 60 158 72 OMD 6.96 22 51 73 PI16 6.95 8 13 74 PTGES 6.95 5 10 75 CFH 6.92 68 103 76 SERPING1 6.91 26 78 77 GGT5 6.91 4 5 78 MFAP2 6.86 25 65 79 IGF2 6.85 43 132 80 LHFPL6 6.80 1 3 81 OSR1 6.79 1 5 82 TIMP3 6.72 3 3 83 FXYD1 6.71 76 148 84 VIT 6.70 2 2 85 HSPB2-C11orf52 6.69 11 30 86 HSPB2 6.69 11 30 87 IGF1 6.66 36 77 88 COL6A2 6.65 34 82 89 SPARC 6.64 1 2 90 VEGFD 6.61 — — 91 SMOC2 6.61 3 11 92 TWIST2 6.59 4 6 93 FAM180B 6.52 — — 94 IGFBP3 6.51 17 93 95 PLTP 6.50 18 36 96 RAMP2 6.49 8 18 97 GSC 6.39 336 487 98 TNMD 6.38 — — 99 SVEP1 6.37 1 1 100 HTRA3 6.34 4 12 101 CPZ 6.34 11 38 102 MGST1 6.33 2 1 103 AEBP1 6.26 4 12 104 DIO3OS 6.25 1 2 105 CYGB 6.25 7 7 106 PDGFRA 6.25 9 40 107 BGN 6.24 — — 108 CPXM1 6.23 3 19 109 ACKR4 6.22 10 22 110 AKR1C2 6.20 12 28 111 APOE 6.18 351 1,543 112 RNASE4 6.17 5 7 113 ANG 6.17 5 7 114 ANGPTL2 6.17 6 16 115 COL6A1 6.16 35 85 116 TMEM176A 6.16 50 102 117 MEDAG 6.16 0 0 118 SCARA5 6.15 17 28 119 CRABP2 6.15 3 4 120 COL14A1 6.14 12 22 121 PMP22 6.14 4 13 122 AKR1C1 6.13 23 57 123 C1QTNF7 6.13 3 9 124 ADIRF 6.12 5 6 125 CST3 6.10 — — 126 NUPR1 6.10 22 50 127 MRGPRF 6.09 34 97 128 AGTR1 6.08 9 10 129 ADM 6.08 22 57 130 FIBIN 6.07 1 9 131 NNMT 6.03 19 24 132 IGFBP5 5.99 6 11 133 SLIT3 5.99 6 23 134 LINC01140 5.96 1 4 135 HTRA1 5.95 21 46 136 LINC00603 5.94 0 0 137 C16orf89 5.91 0 0 138 CAVIN3 5.91 0 0 139 ABCA8 5.90 83 140 140 IGFBP7 5.89 21 47 141 TMEM176B 5.88 39 71 142 CHL1 5.87 0 0 143 ABI3BP 5.86 6 6 144 SELENOP 5.86 3 4 145 FST 5.86 15 35 146 ELN 5.82 15 47 147 DCLK1 5.82 0 0 148 MYL9 5.80 7 17 149 TAGLN 5.80 25 92 150 EPHX1 5.78 4 4 151 SSPN 5.78 10 13 152 SERPINA5 5.77 359 512 153 PLPP3 5.77 50 135 154 SPON2 5.76 23 69 155 TNFAIP6 5.75 2 12 156 CPE 5.71 1 1 157 TMEM254 5.70 16 29 158 LMO3 5.69 3 4 159 LINC00645 5.68 3 2 160 CAVIN1 5.66 38 80 161 RSPO3 5.65 29 81 162 FMOD 5.63 9 18 163 GLT8D2 5.62 1 1 164 OLFML2B 5.61 9 18 165 S100A13 5.61 8 14 166 EMX2OS 5.61 4 10 167 CALD1 5.59 21 57 168 LOX 5.57 5 18 169 CAV1 5.56 15 135 170 COL12A1 5.55 1 1 171 SFRP4 5.54 12 39 172 ANGPTL4 5.53 66 465 173 NXPH3 5.52 3 9 174 LINC01436 5.52 0 1 175 LMOD1 5.51 34 89 176 HOXC9 5.49 6 8 177 FMO2 5.49 15 16 178 ABCB5 5.49 3 4 179 TFPI 5.48 54 106 180 CDO1 5.46 5 17 181 OSR2 5.46 0 0 182 HOXC8 5.46 5 6 183 ECM2 5.45 27 58 184 PTGFR 5.42 8 36 185 ADH1C 5.40 133 303 186 ELANE 5.36 31 86 187 CLU 5.36 11 28 188 BPIFB4 5.35 0 0 189 IL33 5.34 1 2 190 SRPX2 5.33 — — 191 ABCA6 5.33 109 193 192 IFI27 5.31 332 479 193 NDN 5.31 — — 194 TMEM37 5.30 6 11 195 RCN3 5.29 60 188 196 ANGPTL1 5.29 6 26 197 FAP 5.27 0 0 198 LAMA4 5.27 10 12 199 FGF16 5.26 — — 200 PDGFRB 5.26 11 25 201 EMX2 5.26 4 10 202 HRCT1 5.24 18 74 203 GAS6 5.23 6 25 204 DMRT3 5.22 8 27 205 FMO1 5.22 4 2 206 NOX4 5.22 9 56 207 C1QTNF2 5.20 0 0 208 GNG11 5.20 3 3 209 COX7A1 5.19 2 5 210 LINC02202 5.18 10 13 211 ITM2A 5.17 — — 212 FGF10 5.15 — — 213 STEAP1 5.13 7 30 214 OGN 5.13 8 17 215 GPX8 5.12 8 21 216 TGFB1I1 5.11 6 16 217 IL11RA 5.09 0 0 218 HOXD-AS2 5.09 12 47 219 HOXC10 5.06 0 0 220 PCDH18 5.05 0 5 221 KDELR3 5.05 7 15 222 RASD1 5.04 20 56 223 DUXA 5.04 0 0 224 CLEC11A 5.04 0 0 225 PPIC 5.03 5 11 226 COL5A2 5.02 17 35 227 LINC01133 5.01 6 11 228 SGCE 5.01 2 4 229 CNTFR 4.99 0 0 230 ADAM33 4.99 20 42 231 EMP1 4.99 5 13 232 LINC01116 4.98 6 23 233 LGALS3BP 4.97 5 5 234 CRYAB 4.97 20 64 235 POSTN 4.96 0 0 236 FSTL1 4.95 1 1 237 NEGR1 4.95 5 12 238 ABCA9 4.95 102 179 239 BMPER 4.94 0 0 240 EFEMP2 4.94 50 111 241 PPL 4.94 2 3 242 EBF1 4.93 13 22 243 SDC2 4.92 1 3 244 MT1M 4.92 29 70 245 THBS2 4.92 7 38 246 LGALS3 4.92 7 33 247 MMP27 4.91 4 4 248 HOXC-AS1 4.89 4 7 249 LINC02381 4.88 10 19 250 KAZALD1 4.86 5 7 251 FABP4 4.86 3 1 252 FKBP10 4.85 15 19 253 XPNPEP2 4.85 — — 254 RERG 4.85 5 14 255 AHNAK2 4.83 2 1 256 ABCA10 4.82 96 171 257 PTGDS 4.82 3 2 258 CYP4B1 4.81 1 8 259 FHL1 4.79 — — 260 PAMR1 4.79 1 2 261 WNT11 4.78 1 1 262 GPC4 4.77 — — 263 ADAMTS2 4.76 9 25 264 ABCC2 4.76 37 70 265 LINC01067 4.76 — — 266 TMEM98 4.76 2 2 267 NRN1 4.76 5 4 268 APOC1 4.75 301 1,434 269 TPPP3 4.75 25 66 270 IGSF10 4.74 3 11 271 HOXA10 4.74 9 12 272 EMILIN1 4.74 14 23 273 SSC5D 4.72 16 44 274 SPRY1 4.72 2 3 275 TSPAN4 4.72 20 57 276 EMP2 4.72 14 22 277 RAI2 4.71 — — 278 TWIST1 4.71 1 1 279 NEXN 4.69 21 71 280 LARP6 4.68 3 2 281 C7 4.66 2 5 282 MFGE8 4.65 17 46 283 PID1 4.64 8 10 284 DBX2 4.64 0 0 285 ACVRL1 4.63 18 37 286 MEG3 4.63 13 43 287 S100A16 4.62 5 8 288 LINC00519 4.62 0 0 289 KRT222 4.61 13 56 290 DKK2 4.61 0 0 291 GFRA1 4.61 1 3 292 C1QTNF5 4.60 8 19 293 ANGPT1 4.60 0 3 294 AKR1C3 4.59 59 224 295 VIM 4.58 32 102 296 ANGPTL5 4.56 3 6 297 CERCAM 4.55 0 0 298 PRSS23 4.55 6 15 299 COMP 4.55 6 12 300 LPAR1 4.54 2 5 301 SHOX2 4.54 0 0 302 FZD4 4.53 4 10 303 CNRIP1 4.53 26 38 304 TNXB 4.52 153 526 305 PTGIS 4.50 2 4 306 S100A4 4.50 2 2 307 SELENBP1 4.49 16 25 308 TMEM221 4.48 10 10 309 ALPL 4.48 11 20 310 LGALS1 4.47 22 66 311 LAMA2 4.45 1 0 312 CYBRD1 4.45 21 56 313 SELENOM 4.44 15 53 314 LINC02172 4.44 0 0 315 FAM180A 4.43 0 0 316 PROCR 4.43 39 86 317 CCL2 4.42 3 12 318 SERPINH1 4.42 22 57 319 SNAI2 4.41 0 0 320 A4GALT 4.41 8 37 321 LINC02130 4.40 — — 322 REM1 4.39 — — 323 INMT-MINDY4 4.38 6 12 324 GALNT16 4.37 5 8 325 CPXM2 4.37 1 1 326 MEST 4.37 3 5 327 LOXL1 4.36 52 110 328 VASN 4.36 28 75 329 ZNF503 4.33 1 2 330 DCAF12L2 4.32 — — 331 F3 4.32 0 0 332 EBF2 4.31 2 2 333 HOXC4 4.30 5 3 334 DIRC1 4.30 21 33 335 GEM 4.30 7 10 336 LINC01712 4.28 0 0 337 CBR3 4.28 1 5 338 PLBD1 4.27 4 7 339 CLMP 4.25 3 5 340 TSHZ2 4.25 6 14 341 MRC2 4.25 14 64 342 MMP23B 4.24 2 14 343 CHI3L1 4.24 9 14 344 EHD2 4.23 3 8 345 HOXC6 4.23 9 9 346 TSKU 4.22 9 19 347 MAP1B 4.22 0 0 348 BHLHE22 4.21 0 0 349 BOC 4.20 4 6 350 ALX1 4.20 0 0 351 INMT 4.19 2 5 352 CTSF 4.19 9 19 353 ASS1 4.18 1 2 354 VGLL3 4.17 5 8 355 DNASE1L3 4.16 28 45 356 HPSE2 4.16 3 5 357 FGF10-AS1 4.16 — — 358 TMEM45A 4.14 5 5 359 KCNE2 4.12 1 3 360 MAP1LC3C 4.12 0 0 361 LINC01914 4.11 7 54 362 NT5E 4.10 0 0 363 ITGBL1 4.10 1 0 364 ADAMTS5 4.10 12 23 365 CADM3 4.09 2 15 366 COLCA1 4.09 16 45 367 FBXO17 4.09 11 19 368 CD302 4.09 13 43 369 CCBE1 4.09 0 1 370 CDKN2C 4.09 0 0 371 CMBL 4.07 0 0 372 WARS2-IT1 4.07 3 17 373 TMEM200B 4.06 1 3 374 LDB2 4.06 2 2 375 MT1A 4.05 27 116 376 MAP1A 4.04 1 2 377 PLA2G5 4.04 3 12 378 FAM162B 4.03 1 6 379 TPM2 4.03 29 79 380 HOXA7 4.02 11 15 381 SPARCL1 4.02 74 301 382 PLAU 4.00 21 55 383 GSTM3 3.99 6 9 384 KIAA0408 3.98 3 3 385 BST1 3.98 2 2 386 S100A6 3.98 3 4 387 CYP7B1 3.97 0 0 388 CFB 3.96 508 1,239 389 LINC00974 3.96 0 0 390 FBLN7 3.95 2 3 391 CRNDE 3.95 0 0 392 ALDH1A1 3.94 5 5 393 IFITM3 3.94 28 58 394 SPOCK1 3.94 0 0 395 PDK4 3.94 5 8 396 CD276 3.93 13 27 397 SFRP1 3.93 2 12 398 ITGA11 3.93 1 2 399 EFHD1 3.93 2 7 400 RAB34 3.93 — — 401 C2 3.91 61 83 402 ANXA2 3.91 8 11 403 C1GALT1C1L 3.90 3 14 404 LVRN 3.90 2 4 405 LINC00644 3.90 1 2 406 MITF 3.90 3 5 407 RARRES1 3.90 2 7 408 MUSTN1 3.89 81 386 409 VCAN 3.88 11 255 410 DBN1 3.88 18 31 411 CIDEC 3.88 0 0 412 EFS 3.88 7 111 413 SPIN2A 3.87 — — 414 HSD11B2 3.86 24 69 415 KCNE4 3.86 2 2 416 ANK2 3.86 0 0 417 SEMA3D 3.86 2 8 418 PDLIM4 3.85 171 263 419 HSD3B7 3.84 46 104 420 FAM114A1 3.84 5 13 421 S100A10 3.83 5 10 422 COL15A1 3.83 10 38 423 SNX21 3.81 10 26 424 FSTL3 3.81 6 5 425 SHCBP1L 3.81 33 97 426 CYP26B1 3.80 5 6 427 ZDHHC1 3.79 22 54 428 SLPI 3.78 33 63 429 LINC02126 3.78 0 0 430 TRIP10 3.78 8 26 431 RBMS3 3.77 1 3 432 KCNK15 3.77 12 19 433 KERA 3.77 1 1 434 ROBO3 3.76 2 2 435 DDR2 3.75 2 2 436 PLSCR4 3.75 0 0 437 CES1 3.75 8 16 438 SRRM3 3.75 1 4 439 ADAMTS12 3.74 1 1 440 ANXA1 3.74 2 2 441 RUNX1T1 3.74 1 1 442 OAF 3.73 9 18 443 P4HA2 3.73 213 354 444 VAT1 3.72 9 12 445 TPBG 3.72 0 0 446 HSPB8 3.72 0 0 447 HOXA3 3.71 20 38 448 FOS 3.71 3 3 449 FKBP9 3.71 6 10 450 LINC00484 3.71 13 14 451 GAS1RR 3.71 0 0 452 ID3 3.71 4 9 453 HSPA1A 3.70 81 205 454 AKAP12 3.70 4 13 455 NPY1R 3.69 2 3 456 RGMA 3.69 3 4 457 SIX1 3.69 0 0 458 MMP14 3.68 28 53 459 FGL2 3.68 2 2 460 COL4A1 3.68 38 107 461 MXRA5 3.68 — — 462 PTPRD-AS1 3.68 1 0 463 PARVA 3.67 0 0 464 LINC01673 3.67 9 20 465 EMCN 3.67 10 11 466 HNMT 3.66 2 2 467 EBF3 3.66 1 1 468 CDH11 3.66 1 5 469 PTGER3 3.65 0 0 470 SMIM10 3.65 — — 471 LAPTM4A 3.64 14 22 472 MAFB 3.64 4 11 473 MASP1 3.63 12 17 474 PDCD1LG2 3.63 1 0 475 CDHR4 3.63 0 0 476 CLIC2 3.61 — — 477 DAB2 3.61 39 81 478 LINC00310 3.61 6 28 479 CCDC146 3.61 4 6 480 COL6A6 3.61 0 0 481 PHYHD1 3.60 15 29 482 GAS1 3.60 0 0 483 EGR1 3.60 1 1 484 TCEAL7 3.60 — — 485 LINC00648 3.59 1 1 486 TIMP1 3.59 — — 487 RASL12 3.59 1 1 488 RAB3IL1 3.59 25 205 489 ACKR3 3.58 2 4 490 MMP19 3.58 0 0 491 PTGIR 3.58 17 25 492 HOXA10-AS 3.58 10 13 493 RBP5 3.58 0 0 494 FKBP7 3.56 0 0 495 COL16A1 3.56 6 12 496 HOXA9 3.56 13 44 497 LEFTY2 3.56 3 3 498 ALDH1A3 3.56 1 4 499 LSP1 3.56 41 132 500 GALNT15 3.56 5 4 501 NPR1 3.55 6 10 502 CCL26 3.55 1 5 503 PRRX2 3.55 4 7 504 LMX1A 3.54 0 0 505 LINC01091 3.54 1 2 506 KLF4 3.54 0 0 507 LINC01886 3.54 0 0 508 ATOH8 3.54 8 12 509 HSPG2 3.54 47 92 510 LINC00517 3.54 0 0 511 GULP1 3.53 28 52 512 LRRC17 3.53 1 1 513 CDON 3.53 4 4 514 CALHM2 3.53 7 15 515 SMOC1 3.52 7 7 516 HOXD8 3.51 14 50 517 SERPINA3 3.51 330 480 518 LINC01048 3.51 0 0 519 IL17D 3.51 2 45 520 PHLDA3 3.50 16 23 521 IRX1 3.50 0 0 522 PSG2 3.50 — — 523 SLC7A10 3.49 65 311 524 RAMP2-AS1 3.49 7 17 525 ADAMTSL1 3.49 2 2 526 TCEAL9 3.49 — — 527 TCF23 3.49 3 6 528 C11orf96 3.48 3 18 529 ARMCX1 3.48 — — 530 TCF4 3.48 9 17 531 IL34 3.48 3 1 532 CD36 3.48 101 134 533 PLPP7 3.48 1 1 534 GFPT2 3.48 3 4 535 COLEC12 3.48 15 23 536 CNN3 3.47 2 3 537 PCAT4 3.47 6 8 538 VCAM1 3.47 0 0 539 CD68 3.46 33 81 540 ZFHX4-AS1 3.46 0 0 541 COL4A2 3.46 31 70 542 BMP4 3.45 31 87 543 FCGRT 3.45 65 213 544 PDPN 3.45 1 9 545 FILIP1L 3.44 16 37 546 SLC29A1 3.44 7 16 547 LRP1 3.43 53 254 548 LINC01539 3.42 0 0 549 ARHGAP20 3.42 0 0 550 LINC01638 3.41 1 2 551 ASPA 3.41 1 1 552 SPR 3.41 0 0 553 LINC01915 3.41 1 1 554 LINC01305 3.41 0 0 555 BIN1 3.41 9 15 556 COPZ2 3.41 25 92 557 COL8A1 3.39 4 14 558 SLC43A3 3.39 27 87 559 DPYSL3 3.39 1 1 560 SCARA3 3.38 16 40 561 IRX6 3.38 2 4 562 TRIL 3.38 3 4 563 AMPH 3.37 3 4 564 RAET1G 3.37 0 0 565 ANTXR1 3.37 1 3 566 LGMN 3.36 6 6 567 CDC42EP2 3.36 0 0 568 LINC01426 3.36 7 17 569 LINC01894 3.35 1 1 570 RCVRN 3.34 0 0 571 TIMP4 3.34 52 199 572 GSTM1 3.34 1 1 573 TUBB6 3.33 3 4 574 NR0B1 3.33 — — 575 CD9 3.33 2 6 576 OLFM1 3.32 4 8 577 FBN1 3.32 21 79 578 PRR16 3.31 5 3 579 CP 3.31 13 19 580 HAND2 3.31 2 5 581 RHOBTB3 3.31 5 10 582 LINC01441 3.30 — — 583 SHISA4 3.30 20 62 584 SIM1 3.30 0 0 585 TSPAN15 3.29 35 53 586 LINC02550 3.29 0 0 587 WDR86 3.28 4 7 588 ARHGEF25 3.27 15 52 589 SLC1A7 3.27 1 7 590 PCDHGC3 3.27 0 0 591 MAB21L1 3.26 0 0 592 IL15RA 3.26 0 0 593 SUSD2 3.26 2 2 594 INHBB 3.26 6 20 595 TUBA8 3.26 7 8 596 EDNRB 3.26 14 41 597 SSX3 3.25 — — 598 RTL8B 3.25 — — 599 SNCG 3.24 0 0 600 CTSL 3.24 2 3 601 TUSC3 3.24 10 10 602 CKB 3.24 18 40 603 CCDC89 3.24 2 1 604 TP53I3 3.23 5 43 605 FHL2 3.23 2 4 606 FNDC4 3.23 488 1,610 607 APOL4 3.22 11 28 608 EGFR 3.22 10 11 609 CRTAP 3.22 7 16 610 ID4 3.21 6 17 611 CYP27A1 3.21 43 170 612 LINC01028 3.20 0 0 613 PDGFD 3.20 2 2 614 HOXA5 3.19 17 40 615 PLEKHH2 3.19 19 44 616 PLAT 3.18 — — 617 RHOJ 3.18 2 6 618 CPED1 3.18 6 14 619 ANPEP 3.18 13 24 620 GPRC5A 3.17 3 6 621 PRICKLE1 3.17 1 2 622 HSD11B1 3.17 16 46 623 FGFR1 3.17 15 23 624 LINC02069 3.17 0 0 625 RBPMS 3.16 31 78 626 SNHG18 3.16 0 0 627 C1QTNF4 3.16 — — 628 C17orf58 3.16 20 50 629 AGAP2-AS1 3.16 7 23 630 MDK 3.16 57 347 631 CDC42EP1 3.16 12 29 632 CYP19A1 3.15 1 0 633 COL5A1 3.15 4 10 634 DDAH2 3.14 146 231 635 LAMC1 3.14 60 136 636 PLS3 3.14 — — 637 HORMAD2-AS1 3.14 15 52 638 BICC1 3.14 22 101 639 PTMS 3.14 15 37 640 GAL 3.13 6 12 641 LINC01985 3.13 1 2 642 LINC02518 3.13 1 2 643 RTN2 3.12 21 92 644 GNG12 3.12 13 26 645 NPB 3.12 0 0 646 TRIM47 3.12 58 138 647 ALDH1L2 3.12 0 0 648 HSPA6 3.11 198 266 649 GAL3ST4 3.11 0 0 650 LINC01239 3.11 3 4 651 LTBP4 3.11 57 146 652 ZFHX4 3.10 0 0 653 NID1 3.10 6 7 654 PKIG 3.10 10 20 655 LRRC32 3.10 3 3 656 LINC01779 3.10 2 1 657 LMNA 3.10 18 37 658 DEPTOR 3.10 9 15 659 CREB3L1 3.10 51 329 660 FAM20A 3.10 34 62 661 LAMB2 3.09 16 40 662 DLC1 3.09 24 63 663 MIR99AHG 3.09 3 9 664 PALLD 3.09 6 11 665 CDC42EP5 3.09 1 1 666 PRRG3 3.09 — — 667 CLIP3 3.09 1 1 668 CCDC8 3.08 12 37 669 HAS2-AS1 3.08 5 13 670 DNM3OS 3.08 0 0 671 PCDHB4 3.08 0 0 672 KLHDC8B 3.07 44 134 673 NPY5R 3.07 2 3 674 LINC00567 3.06 0 0 675 PLP1 3.06 — — 676 FN1 3.06 29 100 677 HMCN1 3.05 5 7 678 CSF1 3.05 5 9 679 ACADL 3.04 0 0 680 TSPAN6 3.03 — — 681 AOX1 3.02 2 1 682 CAB39L 3.02 1 3 683 HIC1 3.02 36 105 684 TBX18 3.02 0 0 685 BEX3 3.02 — — 686 RAB7B 3.01 3 5 687 CELA1 3.01 11 44 688 CRISPLD2 3.00 18 52 689 CERS3-AS1 2.99 0 0 690 TMEM100 2.99 0 4 691 LINC01117 2.99 12 46 692 AR 2.98 — — 693 CDC42EP4 2.98 2 4 694 RASL11A 2.98 3 26 695 PLXDC1 2.98 1 3 696 INSRR 2.97 2 2 697 KCNJ8 2.97 4 14 698 PDLIM2 2.97 29 58 699 PHGDH 2.96 0 0 700 PABPC5 2.95 — — 701 RCN1 2.95 5 11 702 MMP28 2.95 4 4 703 TPST1 2.95 3 3 704 LINC00972 2.95 1 0 705 SYDE1 2.95 1 1 706 ENPP2 2.95 8 14 707 PALM 2.95 16 43 708 PPARG 2.94 122 460 709 DNM1 2.94 2 3 710 C6orf132 2.94 24 122 711 AADACL4 2.94 1 0 712 PROS1 2.94 0 0 713 ERICH2 2.94 0 0 714 BHMT2 2.93 37 104 715 LINC01257 2.93 0 2 716 SLC5A3 2.93 6 28 717 RNF212 2.93 9 39 718 PFN2 2.92 0 0 719 MRPS6 2.91 6 28 720 C1QTNF1 2.91 5 9 721 CCDC74A 2.91 0 0 722 MSX1 2.91 0 0 723 SMPDL3A 2.91 1 1 724 LTBR 2.91 21 43 725 PDLIM1 2.90 19 37 726 MARCKS 2.90 1 2 727 LINC00421 2.90 0 0 728 MME 2.89 2 2 729 NID2 2.89 7 17 730 SLC40A1 2.89 7 12 731 IGF2-AS 2.89 40 125 732 KCNS3 2.88 0 1 733 LIMA1 2.88 22 63 734 MATN4 2.87 52 123 735 GLI3 2.87 0 0 736 SEMA3A 2.87 47 59 737 PLA2R1 2.87 12 44 738 CXCL9 2.87 6 5 739 DEFB126 2.86 — — 740 NFIB 2.86 7 15 741 NINJ2 2.86 15 54 742 FRZB 2.86 2 7 743 KITLG 2.85 5 6 744 CPQ 2.85 1 3 745 ATP8B4 2.85 7 22 746 LINC00703 2.85 — — 747 DMRT2 2.85 6 11 748 BDH2 2.84 5 16 749 CA12 2.84 7 15 750 AK1 2.84 7 16 751 CATSPERZ 2.84 7 10 752 IFIT1 2.83 4 4 753 ENG 2.83 9 25 754 ACTA2 2.82 5 5 755 CRIP1 2.82 2 11 756 SP5 2.82 10 21 757 SGCG 2.82 0 0 758 TMEM54 2.82 0 1 759 LY96 2.82 3 3 760 LINC01354 2.82 1 5 761 PLPP1 2.82 8 17 762 AXL 2.82 13 25 763 COCH 2.82 1 1 764 P2RY12 2.81 0 0 765 HSPA12B 2.81 23 45 766 NENF 2.80 14 43 767 CALHM3 2.80 4 14 768 C8orf48 2.80 7 28 769 TEAD2 2.79 1 2 770 S100A11 2.79 3 3 771 RND3 2.79 0 5 772 NRP1 2.79 9 18 773 CDKN1C 2.79 12 23 774 MAOB 2.78 — — 775 RIPOR3 2.78 4 10 776 CYP4X1 2.77 11 16 777 TNC 2.77 40 75 778 LINC01230 2.77 1 3 779 TEX35 2.77 6 19 780 CLDN11 2.77 0 0 781 C1orf21 2.76 1 0 782 ATF3 2.76 8 26 783 HMGCLL1 2.75 0 0 784 HAND2-AS1 2.75 2 5 785 NAALAD2 2.75 1 2 786 LINC01153 2.75 — — 787 HES1 2.75 0 0 788 HSPA1B 2.74 60 376 789 PDLIM3 2.74 2 4 790 FNDC1 2.74 26 48 791 MLXIPL 2.74 233 1,124 792 MAP7D3 2.73 — — 793 NPDC1 2.73 19 47 794 PRCD 2.73 6 7 795 C8orf88 2.72 0 0 796 FAM110B 2.72 0 0 797 RAB32 2.72 2 1 798 GLB1L 2.72 3 20 799 CD63 2.70 0 0 800 PRDX4 2.70 — — 801 LINC00237 2.70 0 0 802 TMEM150C 2.70 1 1 803 TRIP6 2.69 16 52 804 TMEM35A 2.69 — — 805 CYB5R3 2.69 13 44 806 ALDH2 2.68 51 130 807 WNT2 2.68 10 55 808 SPACA9 2.68 1 0 809 CD151 2.68 20 58 810 HEBP1 2.67 2 5 811 TAX1BP3 2.67 2 2 812 CNPY4 2.67 0 0 813 EXOC1L 2.67 0 0 814 PLAGL1 2.66 21 51 815 LIMS2 2.66 11 14 816 LMCD1 2.66 5 11 817 BASP1 2.65 0 0 818 SLC2A10 2.65 0 0 819 GRM7 2.65 0 0 820 SCPEP1 2.65 1 1 821 LBX2-AS1 2.64 5 13 822 B3GNT8 2.64 7 9 823 LINC00702 2.64 3 3 824 B3GNT9 2.63 16 33 825 UCHL1 2.63 0 0 826 GRINA 2.63 48 90 827 CYB5R2 2.63 0 0 828 TMEM47 2.63 — — 829 SH3D19 2.63 6 10 830 ERRFI1 2.63 3 6 831 CD59 2.63 5 8 832 B4GAT1 2.63 1 2 833 LINC00028 2.63 — — 834 EN1 2.62 13 14 835 TMEM9 2.62 0 1 836 FOXF2 2.62 7 21 837 TKTL1 2.62 — — 838 LINC01124 2.62 4 3 839 EPDR1 2.62 15 39 840 PGRMC1 2.62 — — 841 SGCA 2.61 6 10 842 SERTAD4-AS1 2.60 9 22 843 C14orf180 2.60 0 1 844 EGFLAM 2.60 0 0 845 CEBPD 2.60 3 10 846 SGCB 2.59 — — 847 CMTM3 2.59 23 32 848 PRKG2 2.59 0 0 849 LTBP2 2.59 7 28 850 HYI 2.57 1 2 851 NR2F2 2.57 1 1 852 JRKL-AS1 2.57 0 0 853 MCOLN3 2.57 1 3 854 SLC25A48 2.57 5 8 855 CCDC74B 2.56 0 0 856 LEPR 2.56 13 17 857 IFT22 2.55 15 24 858 LCA5 2.55 0 0 859 ROBO2 2.55 2 1 860 TBX3 2.55 11 38 861 PTCH2 2.55 0 0 862 MOXD1 2.55 7 21 863 CKS1B 2.55 5 10 864 RAB13 2.54 8 20 865 TNFSF13 2.54 27 53 866 LINC01142 2.54 0 0 867 MEG8 2.54 7 22 868 KCND2 2.53 3 3 869 MRGPRF-AS1 2.53 17 58 870 PRTFDC1 2.53 1 2 871 FEZ1 2.53 4 4 872 TIMP2 2.53 2 3 873 ST3GAL4 2.53 37 47 874 GPX4 2.53 30 119 875 FAM228A 2.52 4 31 876 NQO1 2.52 2 4 877 STEAP2 2.52 8 36 878 MAP1LC3A 2.52 0 0 879 SH3BP5 2.52 2 2 880 EGFL6 2.51 — — 881 MEIS1-AS2 2.51 0 0 882 ASIP 2.51 0 0 883 TSPAN3 2.51 14 27 884 ZFP36 2.50 1 0 885 PTGS1 2.50 0 0 886 FILIP1 2.49 2 1 887 MYL6B 2.49 0 0 888 KLF14 2.49 0 0 889 ATL1 2.49 2 11 890 FGF14 2.49 0 0 891 DIO3 2.49 1 2 892 KANK2 2.49 127 940 893 LINC01315 2.49 7 9 894 TCF7L2 2.49 24 62 895 SULF1 2.49 2 3 896 BACE2 2.49 17 18 897 KCNK15-AS1 2.49 13 20 898 PTPRS 2.48 0 2 899 TMEM204 2.48 9 18 900 SNX7 2.48 0 0 901 TMEM247 2.48 — — 902 LINC01834 2.48 0 0 903 CLEC14A 2.48 3 6 904 MSRB3 2.47 0 0 905 MGLL 2.47 16 18 906 ISM1 2.47 0 0 907 EYA2 2.47 0 0 908 MAFF 2.47 83 364 909 CAPN6 2.47 — — 910 IL17RC 2.47 1 1 911 C15orf61 2.47 1 1 912 ABCC9 2.47 6 17 913 RHOD 2.46 10 15 914 CYSTM1 2.46 11 14 915 SFTA1P 2.46 1 1 916 USP19 2.46 3 4 917 TMEM35B 2.45 0 0 918 TMEM220 2.45 0 0 919 EVC2 2.45 1 0 920 KRT36 2.45 0 0 921 AIFM2 2.45 0 1 922 RFTN2 2.44 4 34 923 ABHD14A 2.44 0 0 924 GYPC 2.44 3 4 925 ACOT1 2.44 0 0 926 CHEK2 2.44 24 54 927 STMN3 2.43 62 155 928 CYB5A 2.43 26 35 929 P3H3 2.43 12 24 930 MPZL1 2.43 1 1 931 RFX8 2.43 2 3 932 SERPINE2 2.43 6 14 933 NDNF 2.42 0 0 934 RN7SL832P 2.42 0 1 935 STXBP6 2.42 3 2 936 SH3PXD2B 2.42 2 10 937 TNFSF13B 2.42 1 0 938 PLXDC2 2.42 10 22 939 NFIA 2.42 7 14 940 PLPPR2 2.41 1 2 941 ABHD14A-ACY1 2.41 0 0 942 PITX2 2.41 0 0 943 IFITM1 2.40 45 142 944 RASSF9 2.40 0 0 945 LINC02066 2.40 0 0 946 RARG 2.40 1 1 947 CHPF 2.40 4 15 948 HMCN2 2.40 1 2 949 GJA1 2.40 3 10 950 TP53TG3 2.40 — — 951 S100A3 2.40 0 0 952 CD109 2.39 0 0 953 IER3 2.39 247 484 954 CTBP1-AS 2.39 12 46 955 CLSTN2 2.39 0 0 956 SOCS3 2.38 33 147 957 SLIT2 2.38 0 0 958 OLFM2 2.38 2 4 959 RGS9 2.38 2 4 960 SLC43A1 2.38 27 74 961 LINC01625 2.37 3 20 962 SEMA3C 2.37 69 90 963 TMEM121 2.37 0 0 964 PCGF2 2.36 0 2 965 SLC16A4 2.36 0 0 966 MATN2 2.36 6 10 967 LMO7-AS1 2.36 0 0 968 PTGR1 2.36 5 8 969 SULT1A1 2.36 62 131 970 VKORC1 2.36 51 133 971 TMEM14A 2.36 22 63 972 ANXA4 2.35 2 3 973 TNFSF10 2.35 15 24 974 BMP1 2.35 25 61 975 COLEC11 2.35 7 15 976 ADAMTS3 2.35 17 49 977 CRIP2 2.35 0 0 978 TMEM109 2.34 20 74 979 NTAN1 2.34 8 23 980 ZNF667-AS1 2.34 0 0 981 SLC35G2 2.34 46 105 982 MAP3K20 2.34 8 20 983 NTNG1 2.34 0 0 984 FMO3 2.34 16 19 985 IL6 2.34 13 38 986 OPN1LW 2.33 — — 987 CREG1 2.33 4 4 988 EIF4EBP3 2.33 1 1 989 IL13RA1 2.32 — — 990 HAAO 2.32 16 23 991 KCP 2.32 17 44 992 C1orf56 2.32 36 82 993 OXT 2.32 1 2 994 KIRREL1 2.32 8 21 995 NFIC 2.32 15 30 996 CYP11A1 2.32 19 29 997 MT1E 2.31 20 37 998 C1orf54 2.31 7 10 999 WASF3 2.31 6 14 1000 DNAJB1 2.31 1 5