Evidence reports Cell populations ASPC.activated DE genes Static evidence for AI interpretation. These reports provide data for prompting AI and are not intended as a human-facing reading interface. Please visit the Cell Browser , Trait Browser and Genome Browser for interactive browsing. Have fun exploring SCREATE!Association counts use unique genes with 01-High Priority evidence and unique cells in the authored Specific tier (not the IC-score significance threshold). Reverse counts list meta traits and individual traits separately; these are overlapping levels of evidence, not independent totals. Counts cover the full available catalogue, not the displayed rows or sampled UMAP. Unavailable profiles are excluded from reverse counts; a dash means unavailable or an ambiguous identity, not zero. The browser initially shows 50 rows; choose Rows to change this. Complete rows remain in the HTML, and ordinary page links expose any continuation pages for AI readers and crawlers.
ASPC.activated: DE genes
How association tiers are defined — cell–trait and gene–trait SCREATE tier definitions supplied by the atlas curator. This methods note explains the prepared classifications; it does not recompute or change any report scores or tiers.
Cell–trait tiers Cell–trait links Identify cell types whose regulatory activity is associated with a trait’s genetic signal. Required for Specific or Relevant The ICE-CREAM score derived from the mean metacell Z score must be ≥ 5.39, with BOTH nominal and adjusted ICE-CREAM P values ≤ 0.05. Specific (Tier 1) Also meets all cell-set enrichment analysis (CSEA) criteria in at least one tested comparison: nominal P ≤ 0.05 AND adjusted P ≤ 0.05 AND normalized enrichment score (NES) ≥ 1, all in that comparison. This indicates that trait-associated activity is concentrated in this cell type relative to the tested background. Relevant (Tier 2) Meets the ICE-CREAM requirements but not the additional CSEA criteria. The cell type may share trait-associated activity with other cell types. Interpretation and report values CSEA is cell-set enrichment analysis, analogous to gene-set enrichment analysis but using sets of cells along a ranked list of ICE-CREAM scores. The eligibility score derived from the mean metacell Z score is not the displayed mean IC score. Do not infer a tier from the displayed mean, its descriptive Significance column, or a single CSEA summary value. Reports preserve prepared tiers; Other means an available association outside Specific/Relevant, and unavailable is not zero or proof of biological irrelevance. Meta traits and individual traits Use the prepared tier for the exact meta trait or individual trait. A meta trait’s Best child CSEA FDR is the lowest available child FDR, not a combined or meta-trait significance test. Its displayed mean child NES is descriptive, not a new CSEA test. These summaries must not be used to reconstruct or override the meta-trait tier. Gene–trait priorities (variant–tCRE–gene evidence) Variant–tCRE–gene links Candidate variants connect to genes through overlapping promoters or distal transcribed cis-regulatory elements (tCREs) linked to gene promoters by the Activity-by-Contact (ABC) model. Required genetic support The variant belongs to a purity-passing SuSiE credible set OR qualifies for Borzoi rescue. Borzoi rescue requires BOTH a variant-causality score ≥ 0.3 AND linkage disequilibrium with the lead variant of r² ≥ 0.2. Required cellular support The overlapping promoter has positive tCRE activity OR the distal element has a passing cell-specific ABC link to the gene, in a Specific or Relevant cell subtype (L1S) or fine-grained state (L2). BOTH genetic and cellular support are required for High or Medium priority. High priority Among records meeting both minimum requirements, High requires a genetic score ≥ 0.5 AND a Layer 1 correlation > 0.3 between tCRE activity and the trait’s cellular profile across cell subtypes. Medium priority Meets both minimum requirements but not one or both additional High thresholds. The genetic score is the higher of the SuSiE posterior inclusion probability (PIP) and the Borzoi variant-causality score. Same-record evidence and aggregation Each priority requires genetic and cellular evidence supporting the SAME variant–tCRE–gene record. Do not combine thresholds or evidence from different records to create a qualifying link. A gene receives the highest priority observed among its supporting records. A tCRE summary uses supporting records for that exact tCRE, not every trait of its linked genes. Separately displayed aggregate scores do not relax the same-record rule. Limits of interpretation A priority is candidate-association evidence, not proof of a causal variant, causal gene, causal cell type or treatment efficacy. Missing evidence is unavailable, not zero. MAGMA −log10(P), displayed credibility scores, cellular-context scores and G/C tier codes must not be substituted for these eligibility tests; use the provided records and their documented fields. Meta traits · Individual traits · Gene expression · DE genes DE log fold change is a different metric from mean expression and IC score. This is the complete available browser export, limited upstream to the top 1,000 genes per population; it is not an exhaustive genome-wide differential-expression result.
All 1,000 available exported DE genes
Browsers # Gene DE log fold change Meta traits (High Priority) Individual traits (High Priority)
1 CFD 11.16 32 76 2 CXCL14 11.15 0 0 3 APOD 11.15 0 0 4 DCN 10.78 5 30 5 MGP 10.60 3 8 6 LUM 10.56 5 20 7 MFAP4 9.58 1 6 8 GPC3 9.52 — — 9 ADH1B 9.33 99 251 10 CXCL12 9.29 1 1 11 DPT 9.20 0 1 12 SRPX 8.62 — — 13 SERPINF1 8.49 91 185 14 MYOC 8.49 6 19 15 IGFBP6 8.41 2 2 16 SOD3 8.40 3 3 17 GSN 8.20 10 25 18 PDGFRL 8.10 28 59 19 C1R 8.04 2 4 20 FBLN5 7.98 17 45 21 EFEMP1 7.96 35 109 22 ISLR 7.89 28 62 23 OLFML3 7.88 72 147 24 GPX3 7.87 9 17 25 C1S 7.86 1 3 26 PODN 7.84 4 27 27 MXRA8 7.83 7 40 28 CCDC80 7.81 7 12 29 MFAP5 7.78 — — 30 FBLN1 7.71 4 8 31 AADAC 7.58 1 4 32 PLAC9 7.34 19 33 33 PLA2G2A 7.29 3 13 34 CLEC3B 7.27 5 5 35 CTSK 7.25 91 236 36 XG 7.24 — — 37 CD248 7.23 2 3 38 FGF7 7.16 5 15 39 HSPB6 7.15 1 10 40 SFRP2 7.14 1 4 41 CHRDL1 7.14 — — 42 IGFBP4 7.13 28 80 43 GDF10 7.12 0 0 44 NTRK2 7.11 7 9 45 PRELP 7.09 6 11 46 COL1A2 7.04 19 39 47 CD34 6.99 24 109 48 NOVA1 6.97 0 0 49 PRRX1 6.96 9 22 50 GGT5 6.94 4 5 51 GPNMB 6.93 2 6 52 TNNT3 6.83 24 72 53 COL6A3 6.81 20 54 54 TNMD 6.75 — — 55 FBLN2 6.74 6 13 56 APOE 6.73 351 1,543 57 OLFML1 6.73 1 6 58 ECM1 6.72 60 158 59 TIMP3 6.72 3 3 60 SERPING1 6.71 26 78 61 THY1 6.70 8 20 62 PCOLCE2 6.68 7 20 63 RARRES2 6.67 22 42 64 MMP2 6.67 4 6 65 PTGES 6.65 5 10 66 ITIH5 6.65 4 4 67 RAMP2 6.59 8 18 68 CFH 6.58 68 103 69 ADM 6.57 22 57 70 VIT 6.53 2 2 71 LHFPL6 6.53 1 3 72 TWIST2 6.50 4 6 73 CTHRC1 6.49 0 0 74 GSTM5 6.47 4 7 75 HSPB2-C11orf52 6.47 11 30 76 HSPB2 6.46 11 30 77 HTRA3 6.43 4 12 78 F10 6.43 25 56 79 MGST1 6.43 2 1 80 TMEM119 6.40 11 22 81 IGF1 6.39 36 77 82 COL6A2 6.37 34 82 83 TNFAIP6 6.36 2 12 84 C3 6.36 23 35 85 PCOLCE 6.32 19 63 86 MEDAG 6.32 0 0 87 FXYD1 6.29 76 148 88 IGFBP5 6.28 6 11 89 LRRN4CL 6.27 0 0 90 CPXM1 6.25 3 19 91 MFAP2 6.23 25 65 92 CYGB 6.22 7 7 93 OMD 6.20 22 51 94 CIDEC 6.20 0 0 95 PLTP 6.18 18 36 96 SPARC 6.17 1 2 97 SCARA5 6.16 17 28 98 COL3A1 6.14 3 5 99 RNASE4 6.11 5 7 100 ANG 6.11 5 7 101 CILP 6.08 0 0 102 COL1A1 6.06 9 15 103 IGFBP3 6.05 17 93 104 DUXA 6.03 0 0 105 PDGFRA 6.03 9 40 106 NNMT 6.03 19 24 107 CHL1 6.02 0 0 108 FST 6.02 15 35 109 GSC 6.00 336 487 110 LOX 5.99 5 18 111 VEGFD 5.94 — — 112 DIO3OS 5.94 1 2 113 PMP22 5.93 4 13 114 C1QTNF7 5.92 3 9 115 AGTR1 5.89 9 10 116 PLPP3 5.88 50 135 117 ANGPTL2 5.88 6 16 118 RASD1 5.87 20 56 119 CRABP2 5.87 3 4 120 CAVIN1 5.85 38 80 121 COL6A1 5.85 35 85 122 LINC01140 5.84 1 4 123 OSR1 5.84 1 5 124 SELENOP 5.84 3 4 125 AKR1C1 5.83 23 57 126 SVEP1 5.83 1 1 127 AEBP1 5.83 4 12 128 NUPR1 5.81 22 50 129 EPHX1 5.80 4 4 130 FIBIN 5.79 1 9 131 LINC01436 5.78 0 1 132 SLIT3 5.76 6 23 133 MRGPRF 5.75 34 97 134 FMO2 5.73 15 16 135 AKR1C2 5.72 12 28 136 ELN 5.71 15 47 137 COL12A1 5.69 1 1 138 ANGPTL4 5.64 66 465 139 LMO3 5.64 3 4 140 ADIRF 5.63 5 6 141 OSR2 5.63 0 0 142 CYP4B1 5.63 1 8 143 IGFBP7 5.60 21 47 144 TMEM176A 5.60 50 102 145 EMP1 5.59 5 13 146 CST3 5.58 — — 147 LMOD1 5.56 34 89 148 CAV1 5.54 15 135 149 TMEM37 5.54 6 11 150 ASPN 5.51 23 53 151 FGF10 5.51 — — 152 C7 5.49 2 5 153 MYL9 5.47 7 17 154 CAVIN3 5.46 0 0 155 ACKR4 5.46 10 22 156 SMOC2 5.45 3 11 157 TAGLN 5.45 25 92 158 IGF2 5.44 43 132 159 GLT8D2 5.44 1 1 160 EGR1 5.42 1 1 161 FMOD 5.42 9 18 162 RSPO3 5.41 29 81 163 HSPA6 5.40 198 266 164 TMEM176B 5.40 39 71 165 SSPN 5.39 10 13 166 SPON2 5.38 23 69 167 DCLK1 5.37 0 0 168 TMEM254 5.32 16 29 169 S100A13 5.32 8 14 170 LINC00645 5.31 3 2 171 ELANE 5.31 31 86 172 CDO1 5.31 5 17 173 SERPINA5 5.30 359 512 174 ADH1C 5.30 133 303 175 HTRA1 5.29 21 46 176 NXPH3 5.29 3 9 177 ECM2 5.27 27 58 178 EMX2OS 5.26 4 10 179 CALD1 5.26 21 57 180 PTGFR 5.24 8 36 181 APOC1 5.24 301 1,434 182 SRPX2 5.23 — — 183 C16orf89 5.23 0 0 184 ABCA6 5.19 109 193 185 RAI2 5.18 — — 186 CCL2 5.18 3 12 187 XPNPEP2 5.16 — — 188 KLF4 5.16 0 0 189 THBS2 5.15 7 38 190 HOXC9 5.15 6 8 191 NRN1 5.15 5 4 192 CPE 5.14 1 1 193 GAS6 5.14 6 25 194 PPL 5.14 2 3 195 CCL26 5.13 1 5 196 CPZ 5.12 11 38 197 TWIST1 5.11 1 1 198 IL33 5.11 1 2 199 PI16 5.09 8 13 200 MAFF 5.08 83 364 201 BMPER 5.08 0 0 202 TFPI 5.07 54 106 203 CRYAB 5.07 20 64 204 ABI3BP 5.05 6 6 205 PCDH18 5.05 0 5 206 NDN 5.04 — — 207 HOXC8 5.01 5 6 208 CNTFR 5.01 0 0 209 OLFML2B 4.99 9 18 210 EMX2 4.99 4 10 211 LAMA4 4.98 10 12 212 ABCA9 4.96 102 179 213 GFRA1 4.94 1 3 214 ABCA8 4.94 83 140 215 FABP4 4.93 3 1 216 NOX4 4.92 9 56 217 LINC02202 4.92 10 13 218 SDC2 4.91 1 3 219 VIM 4.89 32 102 220 EMP2 4.87 14 22 221 STEAP1 4.85 7 30 222 FSTL1 4.84 1 1 223 GEM 4.82 7 10 224 ADAMTS2 4.81 9 25 225 GNG11 4.81 3 3 226 FOS 4.80 3 3 227 PDGFRB 4.80 11 25 228 ITM2A 4.80 — — 229 TGFB1I1 4.79 6 16 230 SMOC1 4.77 7 7 231 LINC00972 4.76 1 0 232 HOXC-AS1 4.76 4 7 233 GPC4 4.75 — — 234 LGALS3BP 4.75 5 5 235 FAM180B 4.75 — — 236 HRCT1 4.74 18 74 237 NEGR1 4.73 5 12 238 ADAM33 4.72 20 42 239 LARP6 4.72 3 2 240 COX7A1 4.71 2 5 241 MAFB 4.71 4 11 242 FHL1 4.69 — — 243 PAMR1 4.67 1 2 244 SGCE 4.67 2 4 245 HOXC10 4.67 0 0 246 LPAR1 4.67 2 5 247 EBF1 4.65 13 22 248 ANGPT1 4.65 0 3 249 LINC02381 4.64 10 19 250 LINC01153 4.63 — — 251 DIRC1 4.63 21 33 252 ZNF503 4.62 1 2 253 MFGE8 4.62 17 46 254 PID1 4.61 8 10 255 ACVRL1 4.59 18 37 256 TMEM221 4.59 10 10 257 DCAF12L2 4.58 — — 258 IL11RA 4.58 0 0 259 ATF3 4.56 8 26 260 MAP1B 4.55 0 0 261 LGALS3 4.55 7 33 262 GPX8 4.54 8 21 263 RCN3 4.54 60 188 264 FKBP10 4.54 15 19 265 GFPT2 4.54 3 4 266 TSKU 4.53 9 19 267 LINC02172 4.52 0 0 268 LINC00603 4.52 0 0 269 VASN 4.52 28 75 270 FAP 4.51 0 0 271 HOXD-AS2 4.51 12 47 272 HSPA1A 4.51 81 205 273 CBR3 4.49 1 5 274 CYP26B1 4.49 5 6 275 MMP27 4.49 4 4 276 ADAMTS5 4.47 12 23 277 CYBRD1 4.45 21 56 278 LINC01916 4.45 — — 279 WNT11 4.44 1 1 280 ASS1 4.44 1 2 281 CNRIP1 4.44 26 38 282 HOXA10 4.44 9 12 283 BGN 4.41 — — 284 SNAI2 4.41 0 0 285 DBX2 4.40 0 0 286 ABCA10 4.40 96 171 287 EHD2 4.40 3 8 288 DKK2 4.39 0 0 289 TMEM98 4.39 2 2 290 CLMP 4.35 3 5 291 SSC5D 4.35 16 44 292 GPRC5A 4.35 3 6 293 LINC01116 4.35 6 23 294 MITF 4.35 3 5 295 GCM2 4.35 — — 296 NEXN 4.34 21 71 297 TSPAN4 4.34 20 57 298 ABCB5 4.34 3 4 299 EFEMP2 4.33 50 111 300 MEST 4.32 3 5 301 AHNAK2 4.32 2 1 302 FMO1 4.31 4 2 303 SHCBP1L 4.31 33 97 304 INHBB 4.31 6 20 305 IRX1 4.30 0 0 306 EMILIN1 4.30 14 23 307 ANGPTL1 4.29 6 26 308 HOXC4 4.28 5 3 309 PDK4 4.28 5 8 310 ANGPT4 4.28 0 0 311 KCNE2 4.27 1 3 312 COL15A1 4.26 10 38 313 COL5A2 4.26 17 35 314 KDELR3 4.25 7 15 315 ARC 4.25 5 4 316 SPOCK1 4.25 0 0 317 FAM162B 4.25 1 6 318 MAP1A 4.22 1 2 319 FGF10-AS1 4.21 — — 320 HOXC6 4.21 9 9 321 CERCAM 4.21 0 0 322 FGF16 4.20 — — 323 CMBL 4.20 0 0 324 IFI27 4.20 332 479 325 MT1M 4.20 29 70 326 CLU 4.19 11 28 327 LGALS1 4.19 22 66 328 ZNF280A 4.19 0 0 329 TSHZ2 4.19 6 14 330 COLCA1 4.19 16 45 331 ID3 4.19 4 9 332 PLBD1 4.18 4 7 333 SPRY1 4.17 2 3 334 RASL12 4.17 1 1 335 IGSF10 4.16 3 11 336 HOXA3 4.15 20 38 337 C11orf96 4.15 3 18 338 SERPINH1 4.15 22 57 339 CCBE1 4.15 0 1 340 FZD4 4.14 4 10 341 PPIC 4.14 5 11 342 PTGDS 4.14 3 2 343 OGN 4.14 8 17 344 CLEC11A 4.13 0 0 345 C14orf180 4.13 0 1 346 LAMA2 4.13 1 0 347 MEG3 4.12 13 43 348 FAM180A 4.12 0 0 349 PTGER3 4.12 0 0 350 AMPH 4.11 3 4 351 EDNRB 4.11 14 41 352 F3 4.11 0 0 353 HSPB8 4.11 0 0 354 CADM3 4.10 2 15 355 S100A4 4.10 2 2 356 MT1A 4.10 27 116 357 RCVRN 4.10 0 0 358 CRNDE 4.09 0 0 359 AKR1C3 4.08 59 224 360 EBF2 4.06 2 2 361 SELENBP1 4.06 16 25 362 LINC01712 4.06 0 0 363 MMP19 4.06 0 0 364 COL14A1 4.05 12 22 365 BOC 4.05 4 6 366 HPSE2 4.04 3 5 367 CTSF 4.04 9 19 368 MYC 4.03 0 0 369 ALX1 4.02 0 0 370 VCAM1 4.02 0 0 371 MUSTN1 4.02 81 386 372 KAZALD1 4.01 5 7 373 SELENOM 4.01 15 53 374 C1QTNF2 4.00 0 0 375 C1QTNF5 3.99 8 19 376 DDR2 3.98 2 2 377 FBXO17 3.98 11 19 378 PPP1R1A 3.97 0 4 379 GALNT15 3.97 5 4 380 VGLL3 3.97 5 8 381 SFRP1 3.96 2 12 382 COL4A1 3.94 38 107 383 LINC01133 3.94 6 11 384 CD276 3.94 13 27 385 A4GALT 3.94 8 37 386 SIX1 3.94 0 0 387 CDKN1A 3.94 19 29 388 SGCG 3.94 0 0 389 CYP7B1 3.93 0 0 390 SPARCL1 3.93 74 301 391 CES1 3.93 8 16 392 MMP14 3.92 28 53 393 S100A16 3.91 5 8 394 TMEM200B 3.90 1 3 395 LINC01539 3.89 0 0 396 LDB2 3.89 2 2 397 SRRM3 3.89 1 4 398 ANK2 3.88 0 0 399 KCNE4 3.87 2 2 400 TNXB 3.86 153 526 401 CD302 3.85 13 43 402 MRC2 3.85 14 64 403 HOXA7 3.84 11 15 404 TPM2 3.83 29 79 405 TRIP10 3.83 8 26 406 TUBA8 3.82 7 8 407 IER3 3.82 247 484 408 ANGPTL5 3.82 3 6 409 DMRT3 3.82 8 27 410 CPXM2 3.81 1 1 411 RERG 3.81 5 14 412 LINC00519 3.81 0 0 413 RGMA 3.81 3 4 414 EFS 3.81 7 111 415 FKBP9 3.80 6 10 416 PARVA 3.80 0 0 417 RASL11A 3.80 3 26 418 LINC00310 3.80 6 28 419 BST1 3.79 2 2 420 TCEAL7 3.77 — — 421 CDKN2C 3.77 0 0 422 DNAJB1 3.76 1 5 423 NT5E 3.76 0 0 424 LINC02126 3.75 0 0 425 ID4 3.75 6 17 426 GALNT16 3.75 5 8 427 MMP28 3.74 4 4 428 SERPINA3 3.73 330 480 429 TIMP4 3.73 52 199 430 TMEM45A 3.71 5 5 431 ATOH8 3.71 8 12 432 PTGIS 3.71 2 4 433 PLA2G5 3.71 3 12 434 LVRN 3.71 2 4 435 SHOX2 3.70 0 0 436 ANXA2 3.70 8 11 437 LINC01230 3.70 1 3 438 FBLN7 3.70 2 3 439 ANXA1 3.69 2 2 440 WDR86 3.69 4 7 441 NPY1R 3.68 2 3 442 RAMP2-AS1 3.68 7 17 443 MLXIPL 3.68 233 1,124 444 S100A6 3.67 3 4 445 FOSB 3.67 10 20 446 RBPMS 3.67 31 78 447 SNX21 3.67 10 26 448 VAT1 3.66 9 12 449 ERRFI1 3.66 3 6 450 ENPP2 3.65 8 14 451 TSPAN15 3.64 35 53 452 WARS2-IT1 3.64 3 17 453 BAG3 3.63 17 43 454 C2 3.62 61 83 455 HNMT 3.62 2 2 456 LINC01920 3.62 0 0 457 ZFP36 3.62 1 0 458 BHLHE22 3.61 0 0 459 EMCN 3.60 10 11 460 SMIM10 3.60 — — 461 FNDC4 3.60 488 1,610 462 LPL 3.59 50 219 463 SEMA3A 3.59 47 59 464 NPR1 3.59 6 10 465 S100A10 3.59 5 10 466 KIAA0408 3.59 3 3 467 GAS1 3.59 0 0 468 PDCD1LG2 3.58 1 0 469 ABCC2 3.58 37 70 470 CRISPLD2 3.58 18 52 471 ITGBL1 3.58 1 0 472 RBMS3 3.58 1 3 473 CD36 3.57 101 134 474 TMEM150C 3.57 1 1 475 SEMA3D 3.57 2 8 476 CDC42EP4 3.57 2 4 477 RAB34 3.56 — — 478 DAB2 3.55 39 81 479 SOCS3 3.55 33 147 480 ALPL 3.55 11 20 481 HSPA1B 3.55 60 376 482 C1GALT1C1L 3.54 3 14 483 ACKR3 3.53 2 4 484 IRX6 3.52 2 4 485 MASP1 3.52 12 17 486 APOL4 3.52 11 28 487 RUNX1T1 3.52 1 1 488 FAM114A1 3.52 5 13 489 ARMCX1 3.51 — — 490 TPBG 3.51 0 0 491 ZDHHC1 3.51 22 54 492 LINC01305 3.50 0 0 493 MXRA5 3.50 — — 494 IFITM3 3.50 28 58 495 DBN1 3.49 18 31 496 MAB21L1 3.49 0 0 497 BIN1 3.49 9 15 498 CTSL 3.49 2 3 499 EBF3 3.47 1 1 500 SP5 3.47 10 21 501 CDH11 3.47 1 5 502 ID1 3.47 — — 503 LINC01239 3.46 3 4 504 TPPP3 3.46 25 66 505 LINC01914 3.46 7 54 506 PLAU 3.46 21 55 507 ANPEP 3.45 13 24 508 SFRP4 3.45 12 39 509 FSTL3 3.45 6 5 510 CSF1 3.44 5 9 511 GULP1 3.43 28 52 512 ALDH1A3 3.43 1 4 513 DNASE1L3 3.43 28 45 514 TCF4 3.43 9 17 515 RARRES1 3.43 2 7 516 PCDHB4 3.42 0 0 517 LINC00974 3.42 0 0 518 PLSCR4 3.42 0 0 519 AKAP12 3.41 4 13 520 CCDC146 3.41 4 6 521 RHOBTB3 3.41 5 10 522 COLEC12 3.41 15 23 523 EFHD1 3.41 2 7 524 HOXA5 3.40 17 40 525 PPARG 3.40 122 460 526 LAPTM4A 3.39 14 22 527 HOXD8 3.39 14 50 528 HBM 3.39 7 8 529 HES1 3.38 0 0 530 TBX3 3.37 11 38 531 GRM7 3.37 0 0 532 ERICH2 3.36 0 0 533 ASPA 3.36 1 1 534 LINC00648 3.36 1 1 535 PLEKHH2 3.36 19 44 536 ARHGAP20 3.35 0 0 537 HAND2 3.35 2 5 538 LINC00484 3.35 13 14 539 COL4A2 3.35 31 70 540 REM1 3.35 — — 541 MAP1LC3C 3.34 0 0 542 CDON 3.34 4 4 543 TCEAL9 3.34 — — 544 KRT222 3.34 13 56 545 JUNB 3.34 9 31 546 PHYHD1 3.34 15 29 547 LINC01426 3.33 7 17 548 DHRS7C 3.33 0 0 549 LRP1 3.33 53 254 550 ADAMTS12 3.33 1 1 551 ROBO3 3.32 2 2 552 CLIC2 3.32 — — 553 NID1 3.32 6 7 554 LINC01091 3.31 1 2 555 PLPP7 3.30 1 1 556 PDLIM4 3.30 171 263 557 SPR 3.30 0 0 558 VCAN 3.29 11 255 559 SLC29A1 3.29 7 16 560 HSPG2 3.29 47 92 561 CRTAP 3.29 7 16 562 LMNA 3.29 18 37 563 ADAMTSL1 3.28 2 2 564 PCDHGC3 3.28 0 0 565 SLPI 3.27 33 63 566 SUSD2 3.27 2 2 567 FKBP7 3.27 0 0 568 HOXA9 3.27 13 44 569 FAM20A 3.27 34 62 570 PROCR 3.27 39 86 571 SPIN2A 3.26 — — 572 CLIP3 3.26 1 1 573 ALDH1A1 3.26 5 5 574 EXOC1L 3.25 0 0 575 SYDE1 3.24 1 1 576 CD68 3.24 33 81 577 EGFR 3.24 10 11 578 IL6 3.23 13 38 579 LINC01985 3.23 1 2 580 CERS3-AS1 3.23 0 0 581 CALHM2 3.23 7 15 582 BMP4 3.23 31 87 583 OLFM1 3.22 4 8 584 KCNS3 3.22 0 1 585 C6orf132 3.22 24 122 586 DIO3 3.21 1 2 587 PCAT4 3.21 6 8 588 GSTM3 3.21 6 9 589 HOXA10-AS 3.21 10 13 590 HSD3B7 3.21 46 104 591 INMT-MINDY4 3.21 6 12 592 DMRT2 3.21 6 11 593 FCGRT 3.20 65 213 594 PTPRD-AS1 3.19 1 0 595 LGMN 3.19 6 6 596 NR4A1 3.19 8 14 597 OAF 3.18 9 18 598 IL15RA 3.18 0 0 599 ALDH1L2 3.17 0 0 600 NTNG1 3.17 0 0 601 GADD45B 3.16 1 1 602 AR 3.16 — — 603 NPY4R2 3.15 — — 604 PKIG 3.15 10 20 605 TEAD2 3.14 1 2 606 TRIL 3.14 3 4 607 PALLD 3.14 6 11 608 ZFHX4 3.14 0 0 609 CKB 3.14 18 40 610 RND3 3.13 0 5 611 RAB3IL1 3.13 25 205 612 P4HA2 3.13 213 354 613 GNG12 3.13 13 26 614 FILIP1L 3.13 16 37 615 ANTXR1 3.12 1 3 616 SLC5A3 3.12 6 28 617 JUN 3.12 0 0 618 MME 3.12 2 2 619 KITLG 3.11 5 6 620 CDKN1C 3.11 12 23 621 LAMC1 3.10 60 136 622 MRPS6 3.10 6 28 623 LINC02550 3.09 0 0 624 CNN3 3.08 2 3 625 LSP1 3.08 41 132 626 SLC43A3 3.08 27 87 627 ACADL 3.08 0 0 628 CDC42EP2 3.08 0 0 629 NPY5R 3.07 2 3 630 RTL8B 3.07 — — 631 DLC1 3.07 24 63 632 TBX18 3.07 0 0 633 AXL 3.07 13 25 634 AOX1 3.06 2 1 635 PTGIR 3.06 17 25 636 CP 3.06 13 19 637 INSRR 3.05 2 2 638 NR0B1 3.05 — — 639 INMT 3.05 2 5 640 LIMA1 3.05 22 63 641 TUBB6 3.04 3 4 642 HMOX1 3.03 2 1 643 COPZ2 3.03 25 92 644 BHMT2 3.03 37 104 645 RHOJ 3.03 2 6 646 FGFR1 3.02 15 23 647 SERPINE1 3.01 25 41 648 PLS3 3.01 — — 649 TMEM100 3.01 0 4 650 LOXL1 3.01 52 110 651 C17orf58 3.01 20 50 652 CYP27A1 3.01 43 170 653 PHLDA3 3.00 16 23 654 TBX5 3.00 13 194 655 ICAM1 3.00 18 31 656 RN7SL832P 3.00 0 1 657 COL16A1 3.00 6 12 658 PRICKLE1 3.00 1 2 659 IL17D 2.99 2 45 660 PRR16 2.98 5 3 661 ARHGEF25 2.98 15 52 662 ITGA11 2.98 1 2 663 FGL2 2.97 2 2 664 TUSC3 2.97 10 10 665 KCNK15 2.97 12 19 666 C1QTNF1 2.97 5 9 667 ACSM5 2.97 12 31 668 LINC01228 2.96 0 0 669 TNFSF13 2.95 27 53 670 AGT 2.95 4 9 671 TMEM35A 2.93 — — 672 MEG8 2.93 7 22 673 SNHG18 2.93 0 0 674 HAS2-AS1 2.93 5 13 675 CHST7 2.93 — — 676 LINC01413 2.91 0 0 677 PDLIM1 2.91 19 37 678 PDLIM3 2.91 2 4 679 FMO3 2.91 16 19 680 RBPMS-AS1 2.90 27 73 681 BDH2 2.90 5 16 682 TRIM47 2.90 58 138 683 CDC42EP1 2.90 12 29 684 HSD11B1 2.89 16 46 685 SLC7A10 2.89 65 311 686 TP53I3 2.89 5 43 687 ARL4D 2.89 14 29 688 ALDH2 2.89 51 130 689 CEBPD 2.89 3 10 690 CATSPERZ 2.88 7 10 691 DDAH2 2.88 146 231 692 CPED1 2.88 6 14 693 SHISA4 2.88 20 62 694 CREB3L1 2.88 51 329 695 EVC2 2.88 1 0 696 RFX8 2.87 2 3 697 PTMS 2.87 15 37 698 CLSTN2 2.87 0 0 699 PRSS23 2.87 6 15 700 PROS1 2.87 0 0 701 SESTD1 2.87 2 58 702 LINC01117 2.87 12 46 703 HIC1 2.87 36 105 704 GAS1RR 2.86 0 0 705 PITX2 2.86 0 0 706 DPYSL3 2.86 1 1 707 LINC00702 2.86 3 3 708 SLC40A1 2.86 7 12 709 SLIT2 2.86 0 0 710 GAL3ST4 2.85 0 0 711 NRP1 2.84 9 18 712 MAOB 2.84 — — 713 RAET1G 2.83 0 0 714 CCDC8 2.83 12 37 715 IGF2-AS 2.83 40 125 716 RTN2 2.82 21 92 717 SOX9 2.82 14 22 718 NFIB 2.81 7 15 719 CFB 2.80 508 1,239 720 FAM110B 2.80 0 0 721 RAB7B 2.80 3 5 722 SP9 2.79 0 0 723 RIPOR3 2.78 4 10 724 DEPTOR 2.78 9 15 725 SLC7A8 2.78 0 0 726 BEX3 2.78 — — 727 RCN1 2.78 5 11 728 CLIP1-AS1 2.78 0 0 729 TIMP1 2.78 — — 730 HMGCLL1 2.77 0 0 731 C8orf88 2.77 0 0 732 PFN2 2.77 0 0 733 BICC1 2.77 22 101 734 AGAP2-AS1 2.77 7 23 735 LINC01312 2.77 1 4 736 PRRX2 2.77 4 7 737 TCF7L2 2.76 24 62 738 LINC01354 2.76 1 5 739 MSRB3 2.76 0 0 740 RGS22 2.76 0 0 741 MSX1 2.76 0 0 742 CCDC89 2.76 2 1 743 CYP19A1 2.75 1 0 744 EGFLAM 2.75 0 0 745 ISM1 2.75 0 0 746 PALM 2.75 16 43 747 SLC25A48 2.75 5 8 748 SERTAD1 2.75 7 24 749 RAB42 2.75 3 2 750 IFIT1 2.74 4 4 751 CD9 2.74 2 6 752 SPACA9 2.74 1 0 753 SIM1 2.73 0 0 754 PHGDH 2.73 0 0 755 LTBR 2.72 21 43 756 CTBP1-AS 2.72 12 46 757 SNX7 2.72 0 0 758 LAMB2 2.71 16 40 759 LINC00452 2.71 — — 760 CPLX4 2.70 — — 761 MAP3K20 2.70 8 20 762 LINC01894 2.70 1 1 763 DNM1 2.69 2 3 764 GPD1 2.69 1 0 765 P2RY12 2.69 0 0 766 FBN1 2.69 21 79 767 PDPN 2.68 1 9 768 ZBTB16 2.68 32 42 769 KLF10 2.67 5 18 770 CCL8 2.67 5 14 771 TSPAN6 2.67 — — 772 PABPC5 2.67 — — 773 AQP7 2.67 15 31 774 PRCD 2.67 6 7 775 PLK2 2.67 5 21 776 SCARA3 2.66 16 40 777 AK1 2.66 7 16 778 CDK15 2.66 0 0 779 PLCD3 2.66 2 18 780 LINC00398 2.65 1 0 781 TMEM47 2.65 — — 782 KCNK15-AS1 2.65 13 20 783 KLHDC8B 2.65 44 134 784 LINC00237 2.65 0 0 785 SMPDL3A 2.64 1 1 786 COCH 2.64 1 1 787 MIR99AHG 2.64 3 9 788 SULF1 2.64 2 3 789 STC2 2.63 3 13 790 ZFHX4-AS1 2.63 0 0 791 MATN3 2.63 17 44 792 SH3D19 2.63 6 10 793 MEIS1-AS2 2.63 0 0 794 FGFBP2 2.63 2 2 795 CA12 2.63 7 15 796 IL17RC 2.62 1 1 797 PRKG2 2.62 0 0 798 PDLIM2 2.62 29 58 799 MAMDC2 2.62 4 9 800 ENG 2.62 9 25 801 PLA2R1 2.61 12 44 802 MAGEE2 2.61 — — 803 PLAGL1 2.61 21 51 804 MRAP 2.61 0 0 805 TRIP6 2.61 16 52 806 PLXDC1 2.61 1 3 807 SH3BP5 2.61 2 2 808 OLFM2 2.61 2 4 809 ACTA2 2.61 5 5 810 HCAR1 2.61 3 10 811 NGFR 2.61 4 11 812 LINC02518 2.60 1 2 813 CYB5A 2.60 26 35 814 CYB5R3 2.59 13 44 815 FAXDC2 2.59 1 1 816 MGLL 2.59 16 18 817 TBX2-AS1 2.58 25 110 818 CDC42EP5 2.58 1 1 819 LRRC32 2.58 3 3 820 PTPRS 2.58 0 2 821 FRZB 2.58 2 7 822 KANK2 2.58 127 940 823 CLDN11 2.57 0 0 824 NFIA 2.57 7 14 825 LMX1A 2.56 0 0 826 CYB5R2 2.56 0 0 827 PLAT 2.56 — — 828 RNF212 2.56 9 39 829 CAB39L 2.56 1 3 830 NAALAD2 2.56 1 2 831 ATP8B4 2.55 7 22 832 LINC00517 2.55 0 0 833 ATL1 2.55 2 11 834 LIMS2 2.54 11 14 835 DNM3OS 2.54 0 0 836 PRTFDC1 2.54 1 2 837 LINC01625 2.54 3 20 838 LGI4 2.54 75 143 839 CPQ 2.53 1 3 840 ABCB11 2.53 22 61 841 ZDHHC9 2.53 — — 842 MAP7D3 2.52 — — 843 CYP4X1 2.52 11 16 844 RHOD 2.52 10 15 845 GRINA 2.52 48 90 846 LINC02066 2.52 0 0 847 HEBP1 2.51 2 5 848 SLC43A1 2.51 27 74 849 PPP1R15A 2.50 44 83 850 LONRF3 2.50 — — 851 PGRMC1 2.50 — — 852 WASF3 2.50 6 14 853 MCOLN3 2.50 1 3 854 CCDC74A 2.50 0 0 855 C8orf48 2.49 7 28 856 TAX1BP3 2.48 2 2 857 LINC01257 2.48 0 2 858 NR1H3 2.47 — — 859 LEPR 2.47 13 17 860 GPX4 2.47 30 119 861 RBP5 2.47 0 0 862 ARHGAP6 2.47 — — 863 MROH9 2.47 1 3 864 LTBP2 2.46 7 28 865 UAP1 2.46 8 8 866 PLP1 2.46 — — 867 PCDHB7 2.46 0 0 868 S100A11 2.46 3 3 869 BDKRB1 2.46 0 0 870 PTGR1 2.45 5 8 871 SFTA1P 2.45 1 1 872 RHOB 2.45 1 1 873 SGCB 2.45 — — 874 RGS16 2.45 5 5 875 LCA5 2.44 0 0 876 NINJ2 2.44 15 54 877 KIRREL1 2.44 8 21 878 MEIS2 2.43 0 0 879 CMTM3 2.43 23 32 880 CRIP1 2.43 2 11 881 LOXL2 2.43 13 42 882 RAB13 2.43 8 20 883 C15orf61 2.43 1 1 884 FHL2 2.43 2 4 885 LTBP4 2.43 57 146 886 TPST1 2.43 3 3 887 PLPP1 2.42 8 17 888 LINC00028 2.42 — — 889 GAL 2.42 6 12 890 HAS2 2.42 5 13 891 CHEK2 2.41 24 54 892 PYGM 2.41 8 16 893 DUSP1 2.40 12 46 894 C1orf21 2.40 1 0 895 NFIC 2.40 15 30 896 LINC01315 2.40 7 9 897 MATN2 2.39 6 10 898 SCPEP1 2.39 1 1 899 ADAMTS1 2.39 8 15 900 FN1 2.39 29 100 901 ZNF423 2.38 10 17 902 GPR146 2.38 19 73 903 CHRD 2.38 2 5 904 SMIM3 2.38 4 4 905 KIAA0930 2.38 8 7 906 RFTN2 2.38 4 34 907 GLB1L 2.38 3 20 908 SLC2A10 2.38 0 0 909 NENF 2.37 14 43 910 BCHE 2.37 2 2 911 AIFM2 2.37 0 1 912 NID2 2.37 7 17 913 MAOA 2.37 — — 914 STK32A 2.36 1 1 915 TNFSF10 2.36 15 24 916 HYI 2.36 1 2 917 TLR3 2.36 24 28 918 RASSF9 2.35 0 0 919 PTGS1 2.35 0 0 920 NAV1 2.35 12 34 921 CXCL2 2.35 12 42 922 IL17RE 2.35 2 2 923 CYSTM1 2.35 11 14 924 RET 2.35 5 4 925 IL20 2.35 12 11 926 TET1 2.35 1 1 927 EGR2 2.35 3 8 928 LINC02185 2.35 0 0 929 LBX2-AS1 2.34 5 13 930 MAP1LC3A 2.34 0 0 931 CLDN23 2.34 63 269 932 METTL27 2.34 35 78 933 ACOX2 2.34 12 16 934 RNF24 2.33 2 2 935 FOXP2 2.33 7 58 936 POSTN 2.33 0 0 937 C6 2.33 2 6 938 NPB 2.33 0 0 939 PXDC1 2.33 5 16 940 COL6A6 2.33 0 0 941 KCND2 2.33 3 3 942 LRRC2 2.32 2 3 943 ZC2HC1A 2.32 0 0 944 NQO1 2.32 2 4 945 ETNK2 2.32 8 22 946 LINC01124 2.32 4 3 947 BIRC7 2.31 7 8 948 FSCN1 2.31 0 0 949 CTSO 2.31 0 6 950 MLF1 2.31 4 11 951 RAB32 2.31 2 1 952 BACE2 2.31 17 18 953 NFATC4 2.30 23 68 954 PDGFD 2.30 2 2 955 CKS1B 2.30 5 10 956 FAM138B 2.30 0 0 957 WASF3-AS1 2.30 0 0 958 STXBP6 2.30 3 2 959 MYLK 2.30 3 5 960 COL8A1 2.29 4 14 961 PRDX4 2.29 — — 962 VSTM4 2.29 7 18 963 RARG 2.29 1 1 964 LINC01686 2.29 10 14 965 LINC01834 2.29 0 0 966 CREG1 2.29 4 4 967 MYADM 2.29 19 22 968 AADACL2-AS1 2.29 1 5 969 HAND2-AS1 2.28 2 5 970 ARHGAP10 2.28 4 6 971 PLXDC2 2.28 10 22 972 NR2F2 2.27 1 1 973 SLITRK2 2.27 — — 974 MDK 2.27 57 347 975 CD63 2.27 0 0 976 IL1R1 2.27 24 48 977 UGDH 2.26 14 26 978 MT-ND1 2.26 — — 979 HP 2.26 120 301 980 TUBB3 2.26 13 31 981 TLN2 2.26 25 55 982 PRRG3 2.26 — — 983 GDF15 2.25 43 83 984 TMEM121 2.25 0 0 985 ROBO2 2.25 2 1 986 IFT22 2.25 15 24 987 LY96 2.24 3 3 988 TMEM220 2.24 0 0 989 TIMP2 2.24 2 3 990 CEBPA 2.24 82 332 991 S100A3 2.23 0 0 992 LINC01886 2.23 0 0 993 EIF4EBP3 2.23 1 1 994 HYKK 2.23 3 5 995 HORMAD2-AS1 2.23 15 52 996 LEPROT 2.23 4 5 997 LRRC34 2.23 1 3 998 CD151 2.22 20 58 999 BASP1 2.22 0 0 1000 FGF14 2.22 0 0