SCREATE

Cell type · L1

muscle_stem_cell

2,765 cells in the full atlas (not the displayed sample).

These are the cell-population annotations shown in the SCREATE Cell Browser.

Read trait, study and gene evidence reports for this population →

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Marker genes

PAX7, MYF5, VCAM1, SPRY1, CDH15

Annotation genes

PAX7, MYF5, VCAM1

Annotation rationales

Muscle stem cells, or satellite cells, reside beneath the skeletal-muscle basal lamina and are maintained by a PAX7-centred quiescence program.

Functional implications

They activate after damage, expand as myogenic progenitors and fuse to repair or replace muscle fibres while renewing the stem-cell pool.

More specific populations

Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.