SCREATE

Cell type · L1

microglia

3,933 cells in the full atlas (not the displayed sample).

These are the cell-population annotations shown in the SCREATE Cell Browser.

Read trait, study and gene evidence reports for this population →

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Marker genes

P2RY12, TMEM119, CX3CR1, C1QA, SALL1

Annotation genes

P2RY12, TMEM119, SALL1

Annotation rationales

Microglia are yolk-sac-derived, central-nervous-system-resident macrophages with a distinct homeostatic surveillance program.

Functional implications

They continuously monitor neural tissue, clear debris, sculpt synapses and coordinate inflammatory and reparative responses to brain injury or disease.

More specific populations

Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.