Cell state · L2
THYMO.proliferative_S
1,594 cells in the full atlas (not the displayed sample).
These are the cell-population annotations shown in the SCREATE Cell Browser.
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Marker genes
ANP32B, CALM3, CARHSP1, CDT1, CENPM, CENPU, CENPW, CFL1, CKS2, COX8A, DDX39A, DEK, DNAJC9, DUT, ERH, HMGA1, HMGB1, HMGB2, HMGB3, HMGN2, HNRNPAB, HNRNPF, LMNB1, LSM4, MAD2L1, MAD2L2, MCM7, NUCKS1, NUDT1, PCLAF, PCNA, PFN1, PRDX2, PSIP1, PTMA, RAN, RANBP1, RPA3, SIVA1, SNRPB, SNRPG, STMN1, TUBA1B, TUBB, TYMS, U2AF1, USP1, YBX1, ZWINT
Annotation genes
CDT1, CENPM, CENPU, MCM7, PCNA, TYMS, ZWINT
Annotation rationales
CDT1/MCM7/PCNA/TYMS mark S-phase licensing/replication; CENPM/CENPU/ZWINT coordinate kinetochore assembly in preparation for mitosis. The set maps to rapid DNA synthesis in the expanding DP pool.
Functional implications
Drive genome duplication and prepare for mitosis during DP expansion; create a large substrate for TCR repertoire selection.
Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.