Cell state · L2
THYMO.SP_CD8_naive
5,679 cells in the full atlas (not the displayed sample).
These are the cell-population annotations shown in the SCREATE Cell Browser.
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Marker genes
ADORA2A, AQP3, BBC3, BTG1, BTG2, CCDC107, CD1C, CD52, CD8A, CD8B, CD9, CLIC3, CPLX1, EEPD1, ELOVL4, FBXL12, FLT3LG, HRK, IL32, ISCU, ISG20, ITM2C, LBH, LINC02273, LTB, PIM2, PTMA, PTPRCAP, RASSF6, RCSD1, SIT1, SNX20, STXBP2, VOPP1, YPEL3
Annotation genes
CD8A, CD8B, ITM2C
Annotation rationales
CD8A/CD8B confirm CD8 lineage; ITM2C associates with maturation/export; BTG1/2 (in markers) support quiescence; ADORA2A adds adenosine sensitivity during egress. The trio (CD8A, CD8B, ITM2C) marks newly matured SP CD8 primed for peripheral naïve pool entry.
Functional implications
Exit thymus as naïve CD8⁺ T cells with intact survival/costimulatory modules, ready for antigen-driven priming.
Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.