Cell state · L2
THYMO.SP_CD4_naive
1,400 cells in the full atlas (not the displayed sample).
These are the cell-population annotations shown in the SCREATE Cell Browser.
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Marker genes
ABLIM1, BACH2, CCR4, CD27, CD28, CD44, CLDN1, GZMM, HLA-E, HSP90B1, ID3, ITM2A, LBR, LY9, NUP155, SELENOI, SIRPG, ST6GAL1, SYTL2, TOX2
Annotation genes
BACH2, CD27, CD28, ID3, ITM2A
Annotation rationales
BACH2 and ID3 enforce naïve fate and restrain effector genes; CD27/CD28 provide survival/co-stimulation competence; ITM2A supports maturation/export. This combination captures newly selected CD4⁺ SP cells with naïve programming.
Functional implications
Complete positive selection and emigrate as naïve CD4⁺ T cells ready for priming in secondary lymphoid organs.
Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.