Cell state · L2
T.gamma_delta.cytotoxic_effector
3,077 cells in the full atlas (not the displayed sample).
These are the cell-population annotations shown in the SCREATE Cell Browser.
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Marker genes
ADGRG1, CX3CR1, FCGR3A, FGFBP2, GNLY, GZMB, GZMH, LAIR2, LGALS1, PRF1, SPON2, ZNF683
Annotation genes
CX3CR1, FCGR3A, FGFBP2, GNLY, GZMB, PRF1, ZNF683
Annotation rationales
PRF1/GZMB/ GNLY define high lytic potential; CX3CR1 promotes vascular patrol; FCGR3A enables antibody-dependent cell-mediated cytotoxicity; FGFBP2 aligns with terminal NK-like cytotoxic states; ZNF683 (Hobit) supports tissue residency/terminal effector fate.
Functional implications
Patrol vasculature and inflamed tissues as NK-like γδ killers executing rapid ADCC and granule-mediated lysis against infected or transformed targets.
Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.