Cell state · L2
T.CD8_Tem.baseline
6,350 cells in the full atlas (not the displayed sample).
These are the cell-population annotations shown in the SCREATE Cell Browser.
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Marker genes
CCL5, CTSW, CX3CR1, GZMB, GZMK, HOPX, IFNG, KLRG1, NKG7, PRF1, S1PR5, ZEB2
Annotation genes
KLRG1
Annotation rationales
KLRG1 marks late effector imprint; CX3CR1 enables vascular crawling/patrolling; GZMB/PRF1 provide hard lysis; HOPX supports tissue persistence; S1PR5 promotes egress. This is the reference Tem killer profile.
Functional implications
Effector-memory surveillance killers: fast IFN-γ/chemokine release, high cytotoxicity, and broad tissue patrolling with quick recall.
Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.