SCREATE

Cell state · L2

T.CD8_Tcm.NK_like

786 cells in the full atlas (not the displayed sample).

These are the cell-population annotations shown in the SCREATE Cell Browser.

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Marker genes

AOAH, CD300A, CHST2, CNR2, CXXC5, FBLN2, FCRL6, ITGAM, KIR3DL2, KLRC2, KLRC3, KLRD1, NCR3, RTKN2, SOX4, SPRY2, VSIG4, XCL1, ZNF683

Annotation genes

KIR3DL2, KLRC2, KLRD1, ZNF683

Annotation rationales

NK receptor array (KIR3DL2, KLRC2, KLRD1) plus ZNF683 (Hobit) suggests adaptive NK-like features; XCL1 recruits XCR1⁺ DCs for cross-priming; CD300A/VSIG4 temper activation.

Functional implications

Rapid innate-like cytotoxic responses with DC cross-talk to amplify local immunity; strong early control of viral replication before full adaptive expansion.

Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.