Cell state · L2
T.CD4_Trm.helper_like
1,589 cells in the full atlas (not the displayed sample).
These are the cell-population annotations shown in the SCREATE Cell Browser.
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Marker genes
ABI3, ARPC4, IL4I1, KLRB1, LGALS3, LTB, OSTF1, PRR5, SIRPG, TMIGD2, ZNRF1
Annotation genes
IL4I1, KLRB1, TMIGD2
Annotation rationales
IL4I1 modulates tryptophan catabolism and dampens T-cell activation; KLRB1 (CD161) links to Th17/ILC circuits; TMIGD2 supports costimulation/adhesion; LTB indicates lymphoid tissue organization cues.
Functional implications
Helper-modulatory Trm that fine-tunes APC and B-cell interactions, likely providing IL-4/IL-17-leaning help while limiting excessive activation via metabolic control.
Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.