Cell state · L2
T.CD4_Trm.central_like
2,578 cells in the full atlas (not the displayed sample).
These are the cell-population annotations shown in the SCREATE Cell Browser.
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Marker genes
CCR4, CCR7, CD55, DCXR, FAAH2, KLF3, LDHB, LEF1, PASK, S1PR1, SCML1, SELL, SESN3, TSHZ2
Annotation genes
CCR7, LEF1, S1PR1, SELL
Annotation rationales
Retained CCR7/SELL/S1PR1 and LEF1 signify a central-memory-like program despite CD4 Trm context—suggesting incomplete residency or a replenishment stream for Trm pools.
Functional implications
Transitional/migratory Trm precursors that balance circulation and retention, refreshing resident niches while preserving plasticity.
Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.