Cell state · L2
T.CD4_Trm.baseline
4,278 cells in the full atlas (not the displayed sample).
These are the cell-population annotations shown in the SCREATE Cell Browser.
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Marker genes
METRNL, CREM, THBS1, MYADM, ATP1B3, TIPARP, PMEPA1, LMNA, FTH1, ANKRD9, ANXA1, CCR9, RGCC, VPS37B, SRGN, ELL2, CXCR3, CD69, RUNX3
Annotation genes
CD69, CXCR3, RUNX3, CREM, ANXA1, TIPARP, PMEPA1, FTH1, SRGN
Annotation rationales
CD69 + RUNX3 program residency and Th1-skewed cytotoxic potential; CXCR3 positions cells at CXCL9/10 inflamed fronts; CCR9 in markers suggests ductal/gut bias. SRGN (granule proteoglycan) and THBS1 imply granule competence and matrix interaction. CREM/TIPARP/PMEPA1 provide AHR/TGF-β feedback brakes; ANXA1/iron handling (FTH1) support resolution and metabolic resilience.
Functional implications
Local sentinels at barriers that: (i) deliver focused cytotoxic/Th1 signals, (ii) recruit/shape myeloid partners, and (iii) protect tissue via TGF-β/AHR/pro-resolving brakes; ideal for quick containment without chronic damage.
Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.