Cell state · L2
OLG.vesicle_trafficking
2,670 cells in the full atlas (not the displayed sample).
These are the cell-population annotations shown in the SCREATE Cell Browser.
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Marker genes
PI4K2B
Annotation genes
PI4K2B
Annotation rationales
PI4K2B (annotation gene) supports phosphoinositide metabolism that controls endo/exocytosis and membrane delivery—critical at the inner tongue and paranodes where continuous lipid/protein insertion is needed to maintain sheath geometry.
Functional implications
Enhance targeted vesicle trafficking and lipid remodeling at myelin membranes, sustaining node/paranode organization and enabling subtle sheath growth or repair.
Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.