Cell state · L2
NEU.INH_VIP.enkephalinergic
77 cells in the full atlas (not the displayed sample).
These are the cell-population annotations shown in the SCREATE Cell Browser.
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Marker genes
ADAMTSL1, DACH2, LMO3, LMO4, PCDH18, PENK, SEMA3C, SOX5
Annotation genes
LMO3, PCDH18, PENK, SOX5
Annotation rationales
PENK marks enkephalin production; LMO3/LMO4/SOX5 specify subtype identity; PCDH18/SEMA3C refine contact specificity. Enkephalins modulate presynaptic release and nociceptive/affective processing.
Functional implications
Provides peptide-mediated inhibition to dampen excitatory drive and stress/pain signals, modulating disinhibitory tone in limbic/sensory circuits and shaping affective state.
Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.