Cell state · L2
NEU.INH_PVALB.metabotropic
165 cells in the full atlas (not the displayed sample).
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Marker genes
BRINP3, CDH2, CDH8, DPY19L1, EPHA5, FAT1, FBN2, GDA, GRID2, GRM1, KCNT2, LRRC7, NDST4, NPAS1, NPAS3, NPY1R, PSD3, PTPRO, RALYL, SH3GL3, SLC8A1, SPON1, TBL1X, THSD7B
Annotation genes
GRID2, GRM1, NPY1R
Annotation rationales
Slow inhibition and plasticity modulation arise from GRM1/GRID2 metabotropic receptors; NPY1R confers peptidergic dampening; adhesion molecules (e.g., CDH2) stabilize microcircuits.
Functional implications
Sets oscillatory “set-points” and metaplastic thresholds, complementing fast PV inhibition with tonic/slow control during learning and state transitions.
Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.