SCREATE

Cell state · L2

NEU.INH_LAMP5.projecting

200 cells in the full atlas (not the displayed sample).

These are the cell-population annotations shown in the SCREATE Cell Browser.

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Marker genes

ATRNL1, CALB1, CHST9, EPHB6, GAP43, GLT8D2, LHX6, NPPC, NRP2, OPCML, OPRM1, RALYL, SEMA6D, SMYD3, TIMP2, TMEM255A, UNC5D

Annotation genes

CALB1, GAP43, LHX6, NRP2, UNC5D

Annotation rationales

LHX6 interneuron program with axon growth GAP43 and guidance NRP2/UNC5D/SEMA6D supports long-range or cross-layer inhibitory projections; CALB1 buffers Ca²⁺ during rapid firing.

Functional implications

Distributes inhibition across layers/distant targets, synchronizing assemblies and shaping temporal windows for plasticity across cortical columns.

Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.