SCREATE

Cell state · L2

NEU.EXC_SYT2.synaptic

194 cells in the full atlas (not the displayed sample).

These are the cell-population annotations shown in the SCREATE Cell Browser.

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Marker genes

ALDOA, APLP2, ARF1, ATP6V0E2, CALM1, CALM2, CALM3, CFL1, CLSTN1, ENO1, GAPDH, MAP1B, NAPB, NDRG4, NDUFA4, NEFL, NEFM, NGRN, NORAD, NRGN, PGAM1, PHYHIP, PINK1, PKM, PPIA, PRNP, RAB3A, RGS4, RPL15, RTN3, SERINC1, SLC17A7, SNAP25, SNCB, STMN2, THY1, TOMM20, TPRG1L, VAMP2, VSNL1, YWHAB

Annotation genes

CALM1, SLC17A7, SNAP25, STMN2, VAMP2

Annotation rationales

Core glutamatergic identity SLC17A7 pairs with high-throughput release (SNAP25/VAMP2/RAB3A) and axonal stability (STMN2/NEFL/NEFM); CALM1/NRGN/VSNL1 fine-tune Ca²⁺ thresholds. Mitochondrial and glycolytic genes sustain energetic cost of rapid firing.

Functional implications

Executes fast, reliable glutamate transmission for high-frequency cortical rhythms and top–down control; robust axonal maintenance enables long-range precision over prolonged activity.

Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.