SCREATE

Cell state · L2

NEU.EXC_IT.structural

1,832 cells in the full atlas (not the displayed sample).

These are the cell-population annotations shown in the SCREATE Cell Browser.

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Marker genes

AHI1, AKAP8, ANKRD20A1, EPB41L2, ANKRD36B, AP1G2, CDK11A, CHD5, CSNK2A3, GOLGA8B, HYDIN, NPIPA1, NPIPB13, PILRA, PUM3

Annotation genes

AP1G2, CDK11A, HYDIN

Annotation rationales

AP1G2/GOLGA8B highlight vesicle sorting and Golgi dynamics; HYDIN implicates centrosome/cilia-related cytoskeleton that can influence axon initial segment organization; CDK11A/CHD5 regulate transcription/splicing.

Functional implications

Maintains high-throughput trafficking and structural integrity needed for the intense synaptic turnover of associative IT networks, ensuring stable firing despite heavy plastic demands.

Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.