Cell state · L2
NEU.EXC_IT.guidance
2,160 cells in the full atlas (not the displayed sample).
These are the cell-population annotations shown in the SCREATE Cell Browser.
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Marker genes
ACVR1C, CERKL, DOCK10, EPHA6, PTPRO, GALNT13, GNAL, GREB1L, ITGA4, LAMP5, MEIS2, NEUROD1, SEMA3C, STXBP6, CDH9
Annotation genes
DOCK10, ITGA4, SEMA3C
Annotation rationales
Long-range pathfinding relies on SEMA3C/EPHA6/CDH9 gradients; DOCK10 coordinates actin dynamics for axon extension; ITGA4 mediates adhesion to guidance substrates. MEIS2/NEUROD1 support late differentiation, while GNAL integrates neuromodulatory cues.
Functional implications
Establishes precise callosal tract topology and maintains adhesion during growth. Ensures accurate area-to-area wiring that underpins multisensory binding and higher cognition.
Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.