Cell state · L2
NEU.EXC_IT.callosal
1,849 cells in the full atlas (not the displayed sample).
These are the cell-population annotations shown in the SCREATE Cell Browser.
Read trait, study and gene evidence reports for this population →
Explore this population in Cell Browser →
Marker genes
ADCYAP1, ADGRF5, CALB1, PIK3C2G, CNGB1, COL5A2, GRB14, LAMA2, NFIB, NTNG1, SYT10, ZBBX
Annotation genes
ADCYAP1, NTNG1, SYT10
Annotation rationales
Superficial IT identity (CALB1) combines with callosal organizer NTNG1 to wire interhemispheric links. Peptidergic ADCYAP1 modulates excitability and plasticity; SYT10 supports fast Ca²⁺-triggered exocytosis. NFIB/LAMA2 aid axon guidance and myelination.
Functional implications
Drives bilateral coordination and associative integration: high-frequency output (SYT10) supports precise timing, while ADCYAP1 tunes network gain across hemispheres for attention and context binding.
Marker and functional descriptions are atlas annotations. Explore gene expression, trait associations and regulatory elements in the interactive browsers; see the browser guide.